Binhua Ling

Summary

Affiliation: Tulane University
Country: USA

Publications

  1. pmc Genistein interferes with SDF-1- and HIV-mediated actin dynamics and inhibits HIV infection of resting CD4 T cells
    Jia Guo
    National Center for Biodefense and Infectious Diseases, Department of Molecular and Microbiology, George Mason University, Manassas VA 20110, USA
    Retrovirology 10:62. 2013
  2. pmc The large intestine as a major reservoir for simian immunodeficiency virus in macaques with long-term, nonprogressing infection
    Binhua Ling
    Tulane National Primate Research Center, Tulane University Health Sciences Center, Covington, Louisiana 70433, USA
    J Infect Dis 202:1846-54. 2010
  3. doi request reprint Nonpathogenic CCR2-tropic SIVrcm after serial passage and its effect on SIVmac infection of Indian rhesus macaques
    Binhua Ling
    Division of Comparative Pathology, Tulane National Primate Research Center, Tulane University Health Sciences Center, Covington, LA 70433, USA
    Virology 379:38-44. 2008
  4. pmc Control of viremia and maintenance of intestinal CD4(+) memory T cells in SHIV(162P3) infected macaques after pathogenic SIV(MAC251) challenge
    Bapi Pahar
    Tulane National Primate Research Center, Tulane University School of Medicine, Covington, LA 70433, USA
    Virology 387:273-84. 2009
  5. ncbi request reprint Early restoration of mucosal CD4 memory CCR5 T cells in the gut of SIV-infected rhesus predicts long term non-progression
    Binhua Ling
    Tulane National Primate Research Center, Covington, Louisianna, USA
    AIDS 21:2377-85. 2007
  6. pmc Classic AIDS in a sooty mangabey after an 18-year natural infection
    Binhua Ling
    Tulane National Primate Research Center, 18703 Three Rivers Rd, Covington, LA 70433, USA
    J Virol 78:8902-8. 2004
  7. pmc Detection and partial characterization of simian immunodeficiency virus SIVsm strains from bush meat samples from rural Sierra Leone
    Cristian Apetrei
    Microbiology Division, Tulane National Primate Research Center, 18703 Three Rivers Rd, Covington, LA 70433, USA
    J Virol 79:2631-6. 2005
  8. ncbi request reprint SIV(mac) pathogenesis in rhesus macaques of Chinese and Indian origin compared with primary HIV infections in humans
    Binhua Ling
    Tulane University Health Sciences Center, Department of Tropical Medicine and the Tulane Regional Primate Research Center, Covington, Louisiana 70433, USA
    AIDS 16:1489-96. 2002
  9. pmc The level of monocyte turnover predicts disease progression in the macaque model of AIDS
    Atsuhiko Hasegawa
    Division of Immunology, Tulane National Primate Research Center, Tulane University Health Science Center, Covington, LA 70433, USA
    Blood 114:2917-25. 2009
  10. ncbi request reprint A link between SIVsm in sooty mangabeys (SM) in wild-living monkeys in Sierra Leone and SIVsm in an American-based SM colony
    Binhua Ling
    Tulane National Primate Research Center, Covington, Louisiana 70433, USA
    AIDS Res Hum Retroviruses 20:1348-51. 2004

Collaborators

Detail Information

Publications14

  1. pmc Genistein interferes with SDF-1- and HIV-mediated actin dynamics and inhibits HIV infection of resting CD4 T cells
    Jia Guo
    National Center for Biodefense and Infectious Diseases, Department of Molecular and Microbiology, George Mason University, Manassas VA 20110, USA
    Retrovirology 10:62. 2013
    ..To determine whether inhibiting SDF-1-mediated chemotactic activity can also inhibit HIV infection, we screened several inhibitors known to reduce SDF-1-mediated chemotaxis of T cells...
  2. pmc The large intestine as a major reservoir for simian immunodeficiency virus in macaques with long-term, nonprogressing infection
    Binhua Ling
    Tulane National Primate Research Center, Tulane University Health Sciences Center, Covington, Louisiana 70433, USA
    J Infect Dis 202:1846-54. 2010
    ....
  3. doi request reprint Nonpathogenic CCR2-tropic SIVrcm after serial passage and its effect on SIVmac infection of Indian rhesus macaques
    Binhua Ling
    Division of Comparative Pathology, Tulane National Primate Research Center, Tulane University Health Sciences Center, Covington, LA 70433, USA
    Virology 379:38-44. 2008
    ..These results suggest that SIVrcm is nonpathogenic and may be useful for examining effective immune responses in SIV infection...
  4. pmc Control of viremia and maintenance of intestinal CD4(+) memory T cells in SHIV(162P3) infected macaques after pathogenic SIV(MAC251) challenge
    Bapi Pahar
    Tulane National Primate Research Center, Tulane University School of Medicine, Covington, LA 70433, USA
    Virology 387:273-84. 2009
    ..These results suggest that protection against pathogenic lentiviral infection or disease progression is indeed possible, and may correlate with preservation of mucosal CD4(+) T cells...
  5. ncbi request reprint Early restoration of mucosal CD4 memory CCR5 T cells in the gut of SIV-infected rhesus predicts long term non-progression
    Binhua Ling
    Tulane National Primate Research Center, Covington, Louisianna, USA
    AIDS 21:2377-85. 2007
    ..The key questions addressed were whether or not LTNP experience an early and rapid loss of mucosal CD4 T cells during the acute infection and the mechanisms by which they maintain the LTNP state...
  6. pmc Classic AIDS in a sooty mangabey after an 18-year natural infection
    Binhua Ling
    Tulane National Primate Research Center, 18703 Three Rivers Rd, Covington, LA 70433, USA
    J Virol 78:8902-8. 2004
    ..Therefore, the results also suggest that SMs have a special mechanism for resisting AIDS development...
  7. pmc Detection and partial characterization of simian immunodeficiency virus SIVsm strains from bush meat samples from rural Sierra Leone
    Cristian Apetrei
    Microbiology Division, Tulane National Primate Research Center, 18703 Three Rivers Rd, Covington, LA 70433, USA
    J Virol 79:2631-6. 2005
    ..In spite of the fact that our study doubles the number of known SIVsm strains from wild SMs, none of the simian strains were close to the groups in which HIV-2 was epidemic (groups A and B)...
  8. ncbi request reprint SIV(mac) pathogenesis in rhesus macaques of Chinese and Indian origin compared with primary HIV infections in humans
    Binhua Ling
    Tulane University Health Sciences Center, Department of Tropical Medicine and the Tulane Regional Primate Research Center, Covington, Louisiana 70433, USA
    AIDS 16:1489-96. 2002
    ..To develop a SIV-rhesus macaque (Rh) model of AIDS that more closely approximates HIV pathogenesis in humans...
  9. pmc The level of monocyte turnover predicts disease progression in the macaque model of AIDS
    Atsuhiko Hasegawa
    Division of Immunology, Tulane National Primate Research Center, Tulane University Health Science Center, Covington, LA 70433, USA
    Blood 114:2917-25. 2009
    ..Our results show the importance of monocyte/macrophages in the pathogenesis of AIDS and suggest the dynamic changes of the monocyte/macrophages as a new marker for AIDS progression...
  10. ncbi request reprint A link between SIVsm in sooty mangabeys (SM) in wild-living monkeys in Sierra Leone and SIVsm in an American-based SM colony
    Binhua Ling
    Tulane National Primate Research Center, Covington, Louisiana 70433, USA
    AIDS Res Hum Retroviruses 20:1348-51. 2004
    ..The discovery of this strain in a wild-living SM also indicates that noninvasive methods can be used for SIV detection from monkey feces collected in the field...
  11. pmc Topically applied recombinant chemokine analogues fully protect macaques from vaginal simian-human immunodeficiency virus challenge
    Ronald S Veazey
    Tulane National Primate Research Center, Covington, Louisiana, USA
    J Infect Dis 199:1525-7. 2009
    ..These highly potent molecules, which are amenable to low-cost production, represent promising new additions to the microbicides pipeline...
  12. ncbi request reprint Decreased CCR5 expression on CD4+ T cells of SIV-infected sooty mangabeys
    Ronald Veazey
    National Primate Research Center, Tulane University Health Sciences Center, Covington, Louisiana 70433, USA
    AIDS Res Hum Retroviruses 19:227-33. 2003
    ....
  13. pmc Noninvasive detection of new simian immunodeficiency virus lineages in captive sooty mangabeys: ability to amplify virion RNA from fecal samples correlates with viral load in plasma
    Binhua Ling
    Aaron Diamond AIDS Research Center, New York, New York 10016, USA
    J Virol 77:2214-26. 2003
    ..These assays will be useful for studying the phylogeny and epidemiology of SIVsm infections in the wild, and they hold promise as tools for investigating natural SIV infections in endangered nonhuman primates...
  14. ncbi request reprint Boosting of SIV-specific T cell responses in rhesus macaques that resist repeated intravaginal challenge with SIVmac251
    Barbara L Shacklett
    Gladstone Institute of Virology and Immunology, University of California San Francisco, San Francisco, California 94103, USA
    AIDS Res Hum Retroviruses 18:1081-8. 2002
    ..These results support a protective role for SIVmac-specific T cells in repeatedly exposed, persistently seronegative rhesus macaques...