- Isolation, characterization, and bioactivity of cyclotides from the Micronesian plant Psychotria leptothyrsaSamantha L Gerlach
Department of Ecology and Evolutionary Biology, Tulane University, 6823 St Charles Avenue, New Orleans, LA 70118, USA
J Nat Prod 73:1207-13. 2010..The IC(50) values of psyles A, C, and E were 26, 3.50, and 0.76 muM, respectively. This study expands the number of known rubiaceous cyclotides and shows that the linear cyclotide maintains cytotoxicity...
- Anticancer and chemosensitizing abilities of cycloviolacin 02 from Viola odorata and psyle cyclotides from Psychotria leptothyrsaSamantha L Gerlach
Department of Ecology and Evolutionary Biology, Tulane University, 2863 St Charles Avenue, 400 Boggs Center for Energy and Biotechnology, New Orleans, LA 70118, USA
Biopolymers 94:617-25. 2010..39-0.76 microM). This study documents several cyclotides with robust cytotoxicity that may be promising chemosensitizing agents against drug resistant breast cancer...