Keith S Elmslie

Summary

Affiliation: Tulane University
Country: USA

Publications

  1. ncbi request reprint Calcium channel blockers in the treatment of disease
    Keith S Elmslie
    Department of Physiology, Tulane University Health Science Center, New Orleans, Louisiana 70112, USA
    J Neurosci Res 75:733-41. 2004
  2. ncbi request reprint Neurotransmitter modulation of neuronal calcium channels
    Keith S Elmslie
    Department of Physiology, Tulane University Health Science Center, New Orleans, Louisiana 70112, USA
    J Bioenerg Biomembr 35:477-89. 2003
  3. pmc Slowed N-type calcium channel (CaV2.2) deactivation by the cyclin-dependent kinase inhibitor roscovitine
    Zafir Buraei
    Department of Physiology, Tulane University Health Sciences Center, New Orleans, Louisiana, USA
    Biophys J 89:1681-91. 2005
  4. ncbi request reprint Ca2+ enhances U-type inactivation of N-type (CaV2.2) calcium current in rat sympathetic neurons
    Yong Sook Goo
    Department of Physiology, Tulane University Medical School, New Orleans, Louisiana, USA
    J Neurophysiol 96:1075-83. 2006
  5. ncbi request reprint Roscovitine differentially affects CaV2 and Kv channels by binding to the open state
    Zafir Buraei
    Department of Physiology, Tulane University Health Sciences Center, New Orleans, LA 70112, USA
    Neuropharmacology 52:883-94. 2007
  6. doi request reprint The separation of antagonist from agonist effects of trisubstituted purines on CaV2.2 (N-type) channels
    Zafir Buraei
    Department of Physiology, Tulane University Health Sciences Center, New Orleans, Louisiana, USA
    J Neurochem 105:1450-61. 2008
  7. ncbi request reprint Rapid and reversible block of N-type calcium channels (CaV 2.2) by omega-conotoxin GVIA in the absence of divalent cations
    Haoya Liang
    Department of Physiology, Tulane University Health Science Center, New Orleans, Louisiana 70112, USA
    J Neurosci 22:8884-90. 2002

Collaborators

  • Yong Sook Goo
  • Zafir Buraei
  • Haoya Liang
  • Geoffrey Schofield
  • Mircea Anghelescu

Detail Information

Publications7

  1. ncbi request reprint Calcium channel blockers in the treatment of disease
    Keith S Elmslie
    Department of Physiology, Tulane University Health Science Center, New Orleans, Louisiana 70112, USA
    J Neurosci Res 75:733-41. 2004
    ..The goal of this review is to introduce the various types of calcium channels, their primary physiologic roles, drugs that block these channels, and diseases that are currently being treated with these drugs...
  2. ncbi request reprint Neurotransmitter modulation of neuronal calcium channels
    Keith S Elmslie
    Department of Physiology, Tulane University Health Science Center, New Orleans, Louisiana 70112, USA
    J Bioenerg Biomembr 35:477-89. 2003
    ....
  3. pmc Slowed N-type calcium channel (CaV2.2) deactivation by the cyclin-dependent kinase inhibitor roscovitine
    Zafir Buraei
    Department of Physiology, Tulane University Health Sciences Center, New Orleans, Louisiana, USA
    Biophys J 89:1681-91. 2005
    ..A model where roscovitine reduced a backward rate constant between two open states was able to reproduce the effect of roscovitine on both activation and deactivation...
  4. ncbi request reprint Ca2+ enhances U-type inactivation of N-type (CaV2.2) calcium current in rat sympathetic neurons
    Yong Sook Goo
    Department of Physiology, Tulane University Medical School, New Orleans, Louisiana, USA
    J Neurophysiol 96:1075-83. 2006
    ..Taken together, the data support a role for extracellular divalent cations in modulating U-type inactivation. CDI appears to play a role in N-channel inactivation, but on a slower (sec) time scale...
  5. ncbi request reprint Roscovitine differentially affects CaV2 and Kv channels by binding to the open state
    Zafir Buraei
    Department of Physiology, Tulane University Health Sciences Center, New Orleans, LA 70112, USA
    Neuropharmacology 52:883-94. 2007
    ..Thus, the physiology and pharmacology of slow CaV2 deactivation and potassium channel block must be explored...
  6. doi request reprint The separation of antagonist from agonist effects of trisubstituted purines on CaV2.2 (N-type) channels
    Zafir Buraei
    Department of Physiology, Tulane University Health Sciences Center, New Orleans, Louisiana, USA
    J Neurochem 105:1450-61. 2008
    ..Trisubstituted purine antagonists could become clinically important drugs to treat diseases, such as heart failure and neuropathic pain that result from elevated CaV2 channel activity...
  7. ncbi request reprint Rapid and reversible block of N-type calcium channels (CaV 2.2) by omega-conotoxin GVIA in the absence of divalent cations
    Haoya Liang
    Department of Physiology, Tulane University Health Science Center, New Orleans, Louisiana 70112, USA
    J Neurosci 22:8884-90. 2002
    ..Assuming that the toxin is a pore blocker, our findings are consistent with a model in which Ba2+ interacts at a site on the extracellular surface of the channel to regulate omegaCGVIA dissociation from N-channels...