Luis A Balart

Summary

Affiliation: Tulane University
Country: USA

Publications

  1. pmc Intracellular expression of IRF9 Stat fusion protein overcomes the defective Jak-Stat signaling and inhibits HCV RNA replication
    Bret Poat
    Department of Pathology and Laboratory Medicine, Tulane University Health Sciences Center, 1430 Tulane Avenue, New Orleans, LA 70112, USA
    Virol J 7:265. 2010
  2. doi request reprint Peginterferon α-2a plus ribavirin in Latino and Non-Latino Whites with HCV genotype 1: Histologic outcomes and tolerability from the LATINO Study
    Luis A Balart
    Tulane University Health Sciences Center, New Orleans, Louisiana 70112, USA
    Am J Gastroenterol 105:2177-85. 2010
  3. pmc Free fatty acids induce ER stress and block antiviral activity of interferon alpha against hepatitis C virus in cell culture
    Feyza Gunduz
    Department of Medicine, Gastroenterology and Hepatology, Tulane University Health Sciences Center, New Orleans, LA 70112, USA
    Virol J 9:143. 2012
  4. pmc Impaired expression of type I and type II interferon receptors in HCV-associated chronic liver disease and liver cirrhosis
    Partha K Chandra
    Pathology and Laboratory Medicine, Tulane University Health Sciences Center, New Orleans, Louisiana, United States of America
    PLoS ONE 9:e108616. 2014
  5. pmc Interferon and ribavirin combination treatment synergistically inhibit HCV internal ribosome entry site mediated translation at the level of polyribosome formation
    Rajesh Panigrahi
    Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA
    PLoS ONE 8:e72791. 2013
  6. pmc Interferon alpha induced intrahepatic pSTAT1 inversely correlate with serum HCV RNA levels in chronic HCV infection
    Feyza Gunduz
    Gastroenterology and Hepatology, Tulane University School of Medicine, New Orleans, LA 70112, USA Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA
    Exp Mol Pathol 96:36-41. 2014
  7. pmc Persistent hepatitis C virus infection impairs ribavirin antiviral activity through clathrin-mediated trafficking of equilibrative nucleoside transporter 1
    Rajesh Panigrahi
    Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA
    J Virol 89:626-42. 2015
  8. pmc Mechanism of HCV's resistance to IFN-α in cell culture involves expression of functional IFN-α receptor 1
    Sibnarayan Datta
    Department of Pathology and Laboratory Medicine, Tulane University Health Sciences Center, New Orleans, LA, USA
    Virol J 8:351. 2011
  9. doi request reprint Incidence of liver toxicity in inflammatory bowel disease patients treated with methotrexate: a meta-analysis of clinical trials
    Nabeel Khan
    Section of Gastroenterology and Hepatology at Tulane University Health Sciences Center, New Orleans, Louisiana 70112, USA
    Inflamm Bowel Dis 18:359-67. 2012
  10. pmc Hepatocellular carcinoma xenograft supports HCV replication: a mouse model for evaluating antivirals
    Sidhartha Hazari
    Department of Pathology and Laboratory Medicine, Tulane University Health Sciences Center, New Orleans, LA 70112, USA
    World J Gastroenterol 17:300-12. 2011

Collaborators

Detail Information

Publications11

  1. pmc Intracellular expression of IRF9 Stat fusion protein overcomes the defective Jak-Stat signaling and inhibits HCV RNA replication
    Bret Poat
    Department of Pathology and Laboratory Medicine, Tulane University Health Sciences Center, 1430 Tulane Avenue, New Orleans, LA 70112, USA
    Virol J 7:265. 2010
    ....
  2. doi request reprint Peginterferon α-2a plus ribavirin in Latino and Non-Latino Whites with HCV genotype 1: Histologic outcomes and tolerability from the LATINO Study
    Luis A Balart
    Tulane University Health Sciences Center, New Orleans, Louisiana 70112, USA
    Am J Gastroenterol 105:2177-85. 2010
    ..We sought to compare the histologic response, safety, and tolerability in Latino and non-Latino patients with hepatitis C virus (HCV) genotype 1 treated with peginterferon α-2a plus ribavirin (LATINO study)...
  3. pmc Free fatty acids induce ER stress and block antiviral activity of interferon alpha against hepatitis C virus in cell culture
    Feyza Gunduz
    Department of Medicine, Gastroenterology and Hepatology, Tulane University Health Sciences Center, New Orleans, LA 70112, USA
    Virol J 9:143. 2012
    ..We investigated the effect of hepatocellular steatosis on hepatitis C virus (HCV) replication and IFN-α antiviral response in a cell culture model...
  4. pmc Impaired expression of type I and type II interferon receptors in HCV-associated chronic liver disease and liver cirrhosis
    Partha K Chandra
    Pathology and Laboratory Medicine, Tulane University Health Sciences Center, New Orleans, Louisiana, United States of America
    PLoS ONE 9:e108616. 2014
    ..The goal of this study is to verify whether an increase in ER stress and autophagy response is also associated with the reduced expression of IFNAR1 and RBV transporters in chronic HCV-infected patients...
  5. pmc Interferon and ribavirin combination treatment synergistically inhibit HCV internal ribosome entry site mediated translation at the level of polyribosome formation
    Rajesh Panigrahi
    Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA
    PLoS ONE 8:e72791. 2013
    ..We aimed to determine the synergistic antiviral mechanisms of IFN-α and RBV combination treatment using HCV cell culture...
  6. pmc Interferon alpha induced intrahepatic pSTAT1 inversely correlate with serum HCV RNA levels in chronic HCV infection
    Feyza Gunduz
    Gastroenterology and Hepatology, Tulane University School of Medicine, New Orleans, LA 70112, USA Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA
    Exp Mol Pathol 96:36-41. 2014
    ..Clinical studies show that chronic HCV patients with high viral load show poor response to interferon alpha and ribavirin combination therapy...
  7. pmc Persistent hepatitis C virus infection impairs ribavirin antiviral activity through clathrin-mediated trafficking of equilibrative nucleoside transporter 1
    Rajesh Panigrahi
    Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA
    J Virol 89:626-42. 2015
    ....
  8. pmc Mechanism of HCV's resistance to IFN-α in cell culture involves expression of functional IFN-α receptor 1
    Sibnarayan Datta
    Department of Pathology and Laboratory Medicine, Tulane University Health Sciences Center, New Orleans, LA, USA
    Virol J 8:351. 2011
    ..The results of this study suggest that expression of cell surface IFNAR1 is critical for the response of HCV to exogenous IFN-α...
  9. doi request reprint Incidence of liver toxicity in inflammatory bowel disease patients treated with methotrexate: a meta-analysis of clinical trials
    Nabeel Khan
    Section of Gastroenterology and Hepatology at Tulane University Health Sciences Center, New Orleans, Louisiana 70112, USA
    Inflamm Bowel Dis 18:359-67. 2012
    ..There are limited data on methotrexate's efficacy and safety profile. Our aim was to estimate the hepatotoxicity associated with its use in inflammatory bowel diseases (IBDs)...
  10. pmc Hepatocellular carcinoma xenograft supports HCV replication: a mouse model for evaluating antivirals
    Sidhartha Hazari
    Department of Pathology and Laboratory Medicine, Tulane University Health Sciences Center, New Orleans, LA 70112, USA
    World J Gastroenterol 17:300-12. 2011
    ..To develop a hepatocellular carcinoma (HCC) xenograft model for studying hepatitis C virus (HCV) replication in a mice, and antiviral treatment...
  11. ncbi request reprint Hepatocellular carcinoma, a rapidly increasing public health problem: the Tulane experience 2003-2009
    Naveen Kumar R Tangutur
    Section of Gastroenterology and Hepatology, Tulane University Health Sciences Center, New Orleans, USA
    J La State Med Soc 163:185-90. 2011
    ..Our study confirms the rising incidence of HCC in Louisiana and provides strong support for the rapid implementation of statewide surveillance programs for the early detection of HCC in individuals at risk...