Luis A Balart
Affiliation: Tulane University
- Intracellular expression of IRF9 Stat fusion protein overcomes the defective Jak-Stat signaling and inhibits HCV RNA replicationBret Poat
Department of Pathology and Laboratory Medicine, Tulane University Health Sciences Center, 1430 Tulane Avenue, New Orleans, LA 70112, USA
Virol J 7:265. 2010....
- Peginterferon α-2a plus ribavirin in Latino and Non-Latino Whites with HCV genotype 1: Histologic outcomes and tolerability from the LATINO StudyLuis A Balart
Tulane University Health Sciences Center, New Orleans, Louisiana 70112, USA
Am J Gastroenterol 105:2177-85. 2010..We sought to compare the histologic response, safety, and tolerability in Latino and non-Latino patients with hepatitis C virus (HCV) genotype 1 treated with peginterferon α-2a plus ribavirin (LATINO study)...
- Free fatty acids induce ER stress and block antiviral activity of interferon alpha against hepatitis C virus in cell cultureFeyza Gunduz
Department of Medicine, Gastroenterology and Hepatology, Tulane University Health Sciences Center, New Orleans, LA 70112, USA
Virol J 9:143. 2012..We investigated the effect of hepatocellular steatosis on hepatitis C virus (HCV) replication and IFN-α antiviral response in a cell culture model...
- Mechanism of HCV's resistance to IFN-α in cell culture involves expression of functional IFN-α receptor 1Sibnarayan Datta
Department of Pathology and Laboratory Medicine, Tulane University Health Sciences Center, New Orleans, LA, USA
Virol J 8:351. 2011..The results of this study suggest that expression of cell surface IFNAR1 is critical for the response of HCV to exogenous IFN-α...
- Interferon and ribavirin combination treatment synergistically inhibit HCV internal ribosome entry site mediated translation at the level of polyribosome formationRajesh Panigrahi
Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA
PLoS ONE 8:e72791. 2013..We aimed to determine the synergistic antiviral mechanisms of IFN-α and RBV combination treatment using HCV cell culture...
- Incidence of liver toxicity in inflammatory bowel disease patients treated with methotrexate: a meta-analysis of clinical trialsNabeel Khan
Section of Gastroenterology and Hepatology at Tulane University Health Sciences Center, New Orleans, Louisiana 70112, USA
Inflamm Bowel Dis 18:359-67. 2012..There are limited data on methotrexate's efficacy and safety profile. Our aim was to estimate the hepatotoxicity associated with its use in inflammatory bowel diseases (IBDs)...
- Hepatocellular carcinoma xenograft supports HCV replication: a mouse model for evaluating antiviralsSidhartha Hazari
Department of Pathology and Laboratory Medicine, Tulane University Health Sciences Center, New Orleans, LA 70112, USA
World J Gastroenterol 17:300-12. 2011..To develop a hepatocellular carcinoma (HCC) xenograft model for studying hepatitis C virus (HCV) replication in a mice, and antiviral treatment...
- Hepatocellular carcinoma, a rapidly increasing public health problem: the Tulane experience 2003-2009Naveen Kumar R Tangutur
Section of Gastroenterology and Hepatology, Tulane University Health Sciences Center, New Orleans, USA
J La State Med Soc 163:185-90. 2011..Our study confirms the rising incidence of HCC in Louisiana and provides strong support for the rapid implementation of statewide surveillance programs for the early detection of HCC in individuals at risk...