Richard J Wood

Summary

Affiliation: Tufts University
Country: USA

Publications

  1. ncbi request reprint DNA microarray analysis of vitamin D-induced gene expression in a human colon carcinoma cell line
    Richard J Wood
    Mineral Bioavailability Laboratory, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston 02111, USA
    Physiol Genomics 17:122-9. 2004
  2. ncbi request reprint The iron-heart disease connection: is it dead or just hiding?
    Richard J Wood
    Mineral Bioavailability Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Ageing Res Rev 3:355-67. 2004
  3. doi request reprint Heat shock protein 90beta: a novel mediator of vitamin D action
    Giana Angelo
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Mineral Bioavailability Laboratory, 711 Washington Street, Boston, MA 02111, USA
    Biochem Biophys Res Commun 367:578-83. 2008
  4. pmc Poor iron status is more prevalent in Hispanic than in non-Hispanic white older adults in Massachusetts
    Erin L Seaverson
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Nutr 137:414-20. 2007
  5. ncbi request reprint Dietary factors associated with the risk of high iron stores in the elderly Framingham Heart Study cohort
    Diana J Fleming
    Mineral Bioavailability Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 76:1375-84. 2002
  6. ncbi request reprint Inhibition of lung carcinogenesis by 1alpha,25-dihydroxyvitamin D3 and 9-cis retinoic acid in the A/J mouse model: evidence of retinoid mitigation of vitamin D toxicity
    Heather Mernitz
    Nutrition and Cancer Biology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Int J Cancer 120:1402-9. 2007
  7. ncbi request reprint Dietary phylloquinone depletion and repletion in older women
    Sarah L Booth
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Nutr 133:2565-9. 2003
  8. ncbi request reprint Plasma changes in micronutrients following a multivitamin and mineral supplement in healthy adults
    Miguel Navarro
    Mineral Bioavailability Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
    J Am Coll Nutr 22:124-32. 2003
  9. ncbi request reprint Vitamin D status and the metabolic syndrome
    Ligia A Martini
    USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Nutr Rev 64:479-86. 2006
  10. ncbi request reprint The "anemic" enterocyte in hereditary hemochromatosis: molecular insights into the control of intestinal iron absorption
    Richard J Wood
    Mineral Bioavailability Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Nutr Rev 60:144-8. 2002

Collaborators

Detail Information

Publications22

  1. ncbi request reprint DNA microarray analysis of vitamin D-induced gene expression in a human colon carcinoma cell line
    Richard J Wood
    Mineral Bioavailability Laboratory, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston 02111, USA
    Physiol Genomics 17:122-9. 2004
    ..The known function of these genes suggests that many of them could be involved in the antiproliferative effects of 1,25-dihydroxyvitamin D3...
  2. ncbi request reprint The iron-heart disease connection: is it dead or just hiding?
    Richard J Wood
    Mineral Bioavailability Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Ageing Res Rev 3:355-67. 2004
    ..Moreover, additional efforts need to be made to find a simple, high throughput and more satisfactory measure of the forms of iron in the body that are liable to do damage...
  3. doi request reprint Heat shock protein 90beta: a novel mediator of vitamin D action
    Giana Angelo
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Mineral Bioavailability Laboratory, 711 Washington Street, Boston, MA 02111, USA
    Biochem Biophys Res Commun 367:578-83. 2008
    ..These findings indicate that Hsp90beta is needed for optimal vitamin D responsiveness in the enterocyte and demonstrate a specific role for Hsp90beta in VDR signaling...
  4. pmc Poor iron status is more prevalent in Hispanic than in non-Hispanic white older adults in Massachusetts
    Erin L Seaverson
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Nutr 137:414-20. 2007
    ..Cultural variation in dietary patterns may influence iron availability and body iron stores and contribute to an increased risk for iron deficiency anemia among some Hispanic older adults...
  5. ncbi request reprint Dietary factors associated with the risk of high iron stores in the elderly Framingham Heart Study cohort
    Diana J Fleming
    Mineral Bioavailability Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 76:1375-84. 2002
    ..High body iron stores may increase the risk of several chronic diseases. Whether dietary factors contribute to the risk of high iron stores is unknown...
  6. ncbi request reprint Inhibition of lung carcinogenesis by 1alpha,25-dihydroxyvitamin D3 and 9-cis retinoic acid in the A/J mouse model: evidence of retinoid mitigation of vitamin D toxicity
    Heather Mernitz
    Nutrition and Cancer Biology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Int J Cancer 120:1402-9. 2007
    ..The underlying mechanism behind this effect does not appear to be related to retinoid modulation of vitamin D catabolism...
  7. ncbi request reprint Dietary phylloquinone depletion and repletion in older women
    Sarah L Booth
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Nutr 133:2565-9. 2003
    ..Moreover, our findings suggest that the current recommended Adequate Intake levels of vitamin K (90 micro g/d) in women do not support maximal osteocalcin gamma-carboxylation in older women...
  8. ncbi request reprint Plasma changes in micronutrients following a multivitamin and mineral supplement in healthy adults
    Miguel Navarro
    Mineral Bioavailability Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
    J Am Coll Nutr 22:124-32. 2003
    ....
  9. ncbi request reprint Vitamin D status and the metabolic syndrome
    Ligia A Martini
    USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Nutr Rev 64:479-86. 2006
    ..Recently, the importance of vitamin D status as a risk factor in the development of metabolic syndrome has been the focus of several studies...
  10. ncbi request reprint The "anemic" enterocyte in hereditary hemochromatosis: molecular insights into the control of intestinal iron absorption
    Richard J Wood
    Mineral Bioavailability Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Nutr Rev 60:144-8. 2002
    ..Despite ever-increasing stores of body iron, the inappropriately low iron status of the hereditary hemochromatosis enterocyte continues to drive the hyper-absorption of dietary iron, eventually leading to iron overload...
  11. ncbi request reprint 1,25-Dihydroxyvitamin D and 25-hydroxyvitamin D--mediated regulation of TRPV6 (a putative epithelial calcium channel) mRNA expression in Caco-2 cells
    Shveta Taparia
    Mineral Bioavailability Laboratory, Jean Mayer USDA Human Nutrition, Research Center on Aging, Tufts University, 711 Washington Street, Boston MA 02111, USA
    Eur J Nutr 45:196-204. 2006
    ..TRPV6 mRNA expression is strongly regulated by 1,25-dihydroxyvitamin D (1,25VD), the active hormonal form of vitamin D, in intestine and in Caco-2 cells, a human colon cancer cell line...
  12. doi request reprint Vitamin D and adipogenesis: new molecular insights
    Richard J Wood
    Mineral Bioavailability Laboratory at Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Nutr Rev 66:40-6. 2008
    ....
  13. ncbi request reprint Iron treatment downregulates DMT1 and IREG1 mRNA expression in Caco-2 cells
    Ligia A Martini
    Mineral Bioavailability Laboratory, Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Nutr 132:693-6. 2002
    ....
  14. ncbi request reprint Novel intracellular proteins associated with cellular vitamin D action
    Giana Angelo
    Mineral Bioavailability Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Nutr Rev 60:209-11. 2002
    ..By contrast, a "vitamin D response element-binding protein" inhibits vitamin D receptor binding to the DNA and is responsible for vitamin D resistance in New World primates...
  15. ncbi request reprint Preconception hemoglobin and ferritin concentrations are associated with pregnancy outcome in a prospective cohort of Chinese women
    Alayne G Ronnenberg
    Department of Environmental Health, Harvard School of Public Health, Boston, USA
    J Nutr 134:2586-91. 2004
    ..9, 5.7; P = 0.09) and FGR (OR: 2.7; 95% CI: 1.3, 5.6; P = 0.008). Preconception anemia, particularly iron-deficiency anemia, was associated with reduced infant growth and increased risk of adverse pregnancy outcome in Chinese women...
  16. ncbi request reprint Relative bioavailability of calcium-rich dietary sources in the elderly
    Ligia Martini
    Mineral Bioavailability Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston
    Am J Clin Nutr 76:1345-50. 2002
    ....
  17. ncbi request reprint Comparison of low fat and low carbohydrate diets on circulating fatty acid composition and markers of inflammation
    Cassandra E Forsythe
    Department of Kinesiology, University of Connecticut, 2095 Hillside Road, Unit 1110, Storrs, CT, 06269 1110, USA
    Lipids 43:65-77. 2008
    ..In summary, a very low carbohydrate diet resulted in profound alterations in fatty acid composition and reduced inflammation compared to a low fat diet...
  18. ncbi request reprint A prospective study of serum C-reactive protein and colorectal cancer risk in men
    Marc J Gunter
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
    Cancer Res 66:2483-7. 2006
    ..018). These results support the notion that chronic low-grade inflammation is a marker for increased risk of colorectal cancer...
  19. ncbi request reprint Iron and colorectal cancer risk in the alpha-tocopherol, beta-carotene cancer prevention study
    Amanda J Cross
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD, USA
    Int J Cancer 118:3147-52. 2006
    ..7, 95% CI = 1.4-15.1, p trend = 0.009). In summary, we found a significant inverse association between several serum iron indices and colon cancer risk...
  20. ncbi request reprint Grape polyphenols exert a cardioprotective effect in pre- and postmenopausal women by lowering plasma lipids and reducing oxidative stress
    Tosca L Zern
    Department of Nutritional Sciences, University of Connecticut, Storrs, 06269, USA
    J Nutr 135:1911-7. 2005
    ..Through alterations in lipoprotein metabolism, oxidative stress, and inflammatory markers, LGP intake beneficially affected key risk factors for coronary heart disease in both pre- and postmenopausal women...
  21. ncbi request reprint Vitamin D-inducible calcium transport and gene expression in three Caco-2 cell lines
    James C Fleet
    Department of Foods and Nutrition, Purdue University, West Lafayette, Indiana 47906, USA
    Am J Physiol Gastrointest Liver Physiol 283:G618-25. 2002
    ..Basal CaBP mRNA (86 times greater than P) and protein levels were highest in TC7 cells and were not associated with higher net CaTx, suggesting CaBP may not be rate limiting for CaTx in these cells...
  22. pmc Raisins and additional walking have distinct effects on plasma lipids and inflammatory cytokines
    Michael J Puglisi
    Department of Nutritional Sciences University of Connecticut, Storrs, CT 06269, USA
    Lipids Health Dis 7:14. 2008
    ..The purpose of this study was to determine the effects of consuming raisins, increasing steps walked, or a combination of these interventions on blood pressure, plasma lipids, glucose, insulin and inflammatory cytokines...