C A Wanke

Summary

Affiliation: Tufts University
Country: USA

Publications

  1. ncbi request reprint Clinical evaluation and management of metabolic and morphologic abnormalities associated with human immunodeficiency virus
    Christine A Wanke
    Tufts University School of Medicine, Boston, MA 02111, USA
    Clin Infect Dis 34:248-59. 2002
  2. ncbi request reprint Pathogenesis and consequences of HIV-associated wasting
    Christine Wanke
    Department of Medicine, Tufts University School of Medicine, Boston, MA 02111, USA
    J Acquir Immune Defic Syndr 37:S277-9. 2004
  3. ncbi request reprint Role of acquired immune deficiency syndrome-defining conditions in human immunodeficiency virus-associated wasting
    C A Wanke
    Department of Community Health, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Clin Infect Dis 37:S81-4. 2003
  4. ncbi request reprint Guidelines for using body composition measurement in patients with human immunodeficiency virus infection
    Christine Wanke
    Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    AIDS Patient Care STDS 16:375-88. 2002
  5. ncbi request reprint Alterations in lipid profiles in HIV-infected patients treated with protease inhibitor therapy are not influenced by diet
    Christine Wanke
    Department of Public Health and Nutrition Infection Unit, Tufts University School of Medicine, Boston, MA 02111, USA
    Nutr Clin Pract 20:668-73. 2005
  6. ncbi request reprint Weight loss and wasting remain common complications in individuals infected with human immunodeficiency virus in the era of highly active antiretroviral therapy
    C A Wanke
    Tufts School of Medicine, Boston, MA 02111, USA
    Clin Infect Dis 31:803-5. 2000
  7. ncbi request reprint Collaborative recommendations: the approach to diagnosis and treatment of HIV wasting
    Christine Wanke
    Department of Medicine, Tufts University School of Medicine, Boston, MA 02111, USA
    J Acquir Immune Defic Syndr 37:S284-8. 2004
  8. ncbi request reprint Nutrition and HIV in the international setting
    Christine Wanke
    Nutrition Infection Unit, Department of Public Health and Family Medicine, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Nutr Clin Care 8:44-8. 2005
  9. ncbi request reprint Enteroaggregative Escherichia coli as a potential cause of diarrheal disease in adults infected with human immunodeficiency virus
    C A Wanke
    Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Infect Dis 178:185-90. 1998
  10. ncbi request reprint Malabsorption and wasting in AIDS patients with microsporidia and pathogen-negative diarrhea
    B B Lambl
    Division of Infectious Diseases, New England Deaconess Hospital, Boston, MA 02215, USA
    AIDS 10:739-44. 1996

Research Grants

  1. Nutrition and HIV Progression
    Christine A Wanke; Fiscal Year: 2010
  2. NEMCH CLINICAL RESEARCH ON AIDS TRAINING GRANT
    Christine Wanke; Fiscal Year: 2007
  3. The Impact of Omega three Fatty Acids on Vascular Function and cIMT in HIV
    Christine A Wanke; Fiscal Year: 2010
  4. PROTEASE INHIBITOR RELATED DYSLIPIDEMIA
    Christine A Wanke; Fiscal Year: 2010
  5. The Impact of Omega three Fatty Acids on Vascular Function and cIMT in HIV
    Christine Wanke; Fiscal Year: 2009
  6. PROTEASE INHIBITOR RELATED DYSLIPIDEMIA
    Christine Wanke; Fiscal Year: 2009
  7. PROTEASE INHIBITOR RELATED DYSLIPIDEMIA
    Christine Wanke; Fiscal Year: 2007
  8. MIDCAREER INVESTIGATOR AWARD IN PATIENT ORIENTED RESEA
    Christine Wanke; Fiscal Year: 2007
  9. Feasibility Study of Probiotics for Growth Faltering
    Christine Wanke; Fiscal Year: 2006
  10. PROTEASE INHIBITOR RELATED DYSLIPIDEMIA
    Christine Wanke; Fiscal Year: 2004

Detail Information

Publications44

  1. ncbi request reprint Clinical evaluation and management of metabolic and morphologic abnormalities associated with human immunodeficiency virus
    Christine A Wanke
    Tufts University School of Medicine, Boston, MA 02111, USA
    Clin Infect Dis 34:248-59. 2002
    ..We also suggest treatments and strategies to manage metabolic and morphologic changes in patients with HIV...
  2. ncbi request reprint Pathogenesis and consequences of HIV-associated wasting
    Christine Wanke
    Department of Medicine, Tufts University School of Medicine, Boston, MA 02111, USA
    J Acquir Immune Defic Syndr 37:S277-9. 2004
    ..In patients with HIV wasting, therapies should be directed both at reversing the underlying source of protein energy malnutrition and at other factors that may be contributing to weight loss...
  3. ncbi request reprint Role of acquired immune deficiency syndrome-defining conditions in human immunodeficiency virus-associated wasting
    C A Wanke
    Department of Community Health, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Clin Infect Dis 37:S81-4. 2003
    ..These risks were not altered when adjusted for socioeconomic status, CD4 cell count, energy intake, or baseline BMI. Although ADCs contribute to the development of wasting, their contribution is relatively small...
  4. ncbi request reprint Guidelines for using body composition measurement in patients with human immunodeficiency virus infection
    Christine Wanke
    Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    AIDS Patient Care STDS 16:375-88. 2002
    ..Portability, low cost, ease of use, and patient acceptance make anthropometry and BIA ideally suited for the clinical setting...
  5. ncbi request reprint Alterations in lipid profiles in HIV-infected patients treated with protease inhibitor therapy are not influenced by diet
    Christine Wanke
    Department of Public Health and Nutrition Infection Unit, Tufts University School of Medicine, Boston, MA 02111, USA
    Nutr Clin Pract 20:668-73. 2005
    ..The use of protease inhibitor (PI) -based highly active antiretroviral therapy (HAART) in patients infected with human immunodeficiency virus (HIV) has been linked to alterations in lipid profiles...
  6. ncbi request reprint Weight loss and wasting remain common complications in individuals infected with human immunodeficiency virus in the era of highly active antiretroviral therapy
    C A Wanke
    Tufts School of Medicine, Boston, MA 02111, USA
    Clin Infect Dis 31:803-5. 2000
    ..More than 50% of the cohort was receiving HAART at the time that they met 1 of the definitions of wasting; with regard to the occurrence of wasting; no differences were related to therapy...
  7. ncbi request reprint Collaborative recommendations: the approach to diagnosis and treatment of HIV wasting
    Christine Wanke
    Department of Medicine, Tufts University School of Medicine, Boston, MA 02111, USA
    J Acquir Immune Defic Syndr 37:S284-8. 2004
    ..A collaborative meeting of clinicians and researchers with an interest in HIV wasting was held to evaluate published guidelines in the context of current clinical data...
  8. ncbi request reprint Nutrition and HIV in the international setting
    Christine Wanke
    Nutrition Infection Unit, Department of Public Health and Family Medicine, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Nutr Clin Care 8:44-8. 2005
    ..The introduction of highly active antiretroviral therapy will have a significant impact on the mortality of HIV, but will not completely alleviate the malnutrition associated with HIV infection in the global setting...
  9. ncbi request reprint Enteroaggregative Escherichia coli as a potential cause of diarrheal disease in adults infected with human immunodeficiency virus
    C A Wanke
    Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Infect Dis 178:185-90. 1998
    ..EAggEc may be a pathogen in HIV-infected patients with diarrhea; HIV-infected patients with EAggEc appear to be more symptomatic when HIV disease is more advanced...
  10. ncbi request reprint Malabsorption and wasting in AIDS patients with microsporidia and pathogen-negative diarrhea
    B B Lambl
    Division of Infectious Diseases, New England Deaconess Hospital, Boston, MA 02215, USA
    AIDS 10:739-44. 1996
    ..To define the clinical syndrome, nutritional status and malabsorptive status in patients with HIV and chronic diarrhea and either microsporidia or no identified pathogen...
  11. ncbi request reprint Declines in dietary macronutrient intake in persons with HIV infection who develop depression
    Rita Isaac
    1Nutrition Infection Unit, Department of Public Health and Family Medicine, Tufts University School of Medicine, Boston, MA, USA
    Public Health Nutr 11:124-31. 2008
    ..The effect of depression on dietary intake has not, to our knowledge, been examined in persons with HIV infection...
  12. ncbi request reprint Incidence of metabolic syndrome in a cohort of HIV-infected adults and prevalence relative to the US population (National Health and Nutrition Examination Survey)
    Denise L Jacobson
    Department of Public Health and Family Medicine, Tufts University School of Medicine, 136 Harrison Avenue Posner 4, Boston, MA 02111, USA
    J Acquir Immune Defic Syndr 43:458-66. 2006
    ..Metabolic syndrome increases the risk of cardiovascular outcomes and type II diabetes. Most of the metabolic abnormalities defining metabolic syndrome are observed in HIV...
  13. ncbi request reprint CD4+ cell count, viral load, and highly active antiretroviral therapy use are independent predictors of body composition alterations in HIV-infected adults: a longitudinal study
    Ann Yelmokas McDermott
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Clin Infect Dis 41:1662-70. 2005
    ....
  14. ncbi request reprint Insulin resistance in HIV-infected men and women in the nutrition for healthy living cohort
    Clara Y Jones
    Division of Nutrition and Infectious Disease, Department of Public Health and Family Medicine, Tufts University School of Medicine, Boston, MA 02111, USA
    J Acquir Immune Defic Syndr 40:202-11. 2005
    ..We evaluated insulin resistance (IR) in an HIV-infected cohort and compared our results with those of the National Health and Nutrition Examination Survey III (NHANES III)...
  15. ncbi request reprint Increasing risk of 5% or greater unintentional weight loss in a cohort of HIV-infected patients, 1995 to 2003
    Alice M Tang
    Division of Nutrition and Infection, Department of Family Medicine and Community Health, Tufts University School of Medicine, Boston, MA 02111, USA
    J Acquir Immune Defic Syndr 40:70-6. 2005
    ..This is particularly important because recent studies have shown that even a 5% weight loss in 6 months markedly increases the risk of death...
  16. pmc Regional adipose tissue and elevations in serum aminotransferases in HIV-infected individuals
    Phyllis C Tien
    Department of Medicine, University of California, San Francisco, CA 94121, USA
    J Acquir Immune Defic Syndr 48:169-76. 2008
    ..Obesity is associated with hepatic steatosis, and ALT is a marker of steatosis in the general population...
  17. pmc Incident depression symptoms are associated with poorer HAART adherence: a longitudinal analysis from the Nutrition for Healthy Living study
    Deborah Kacanek
    Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA
    J Acquir Immune Defic Syndr 53:266-72. 2010
    ..To determine the relationship between incident depression symptoms and suboptimal adherence to HIV highly active antiretroviral therapy (HAART)...
  18. pmc Heavy injection drug use is associated with lower percent body fat in a multi-ethnic cohort of HIV-positive and HIV-negative drug users from three U.S. cities
    Alice M Tang
    Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Am J Drug Alcohol Abuse 36:78-86. 2010
    ..The clinical implications of lower body weight in drug using populations are uncertain given that lower mean weights may still fall within the healthy range...
  19. ncbi request reprint The effect of micronutrient supplementation on disease progression and death in simian immunodeficiency virus-infected juvenile male rhesus macaques
    Barry R Goldin
    Department of Public Health and Family Medicine, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    J Infect Dis 192:311-8. 2005
    ..We investigated the impact that micronutrient supplementation has on the progression of simian acquired immunodeficiency syndrome (SAIDS)...
  20. ncbi request reprint Protease inhibitor-based HAART, HDL, and CHD-risk in HIV-infected patients
    Bela F Asztalos
    Lipid Metabolism Laboratory, Jean Mayer USDA Human Nutrition Center on Aging, Tufts University, Boston, MA 02111, USA
    Atherosclerosis 184:72-7. 2006
    ....
  21. ncbi request reprint Prevalence of, evolution of, and risk factors for fat atrophy and fat deposition in a cohort of HIV-infected men and women
    Denise L Jacobson
    Department of Public Health and Family Medicine, Tufts University School of Medicine, Boston, MA 02066, USA
    Clin Infect Dis 40:1837-45. 2005
    ..The risk factors for fat atrophy (FA) and central fat deposition (FD) are multifactorial. We assessed the evolution and predictors of FA and FD in HIV-infected men and women...
  22. ncbi request reprint Difficulty swallowing and lack of receipt of highly active antiretroviral therapy predict acute weight loss in human immunodeficiency virus disease
    Denise L Jacobson
    Department of Family Medicine and Community Health, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Clin Infect Dis 37:1349-56. 2003
    ..Even when HAART is being administered, clinicians should remain vigilant regarding weight loss, oral symptoms, and trouble swallowing...
  23. ncbi request reprint Nutrition and HIV infection: review of weight loss and wasting in the era of highly active antiretroviral therapy from the nutrition for healthy living cohort
    A Mangili
    Division of Geographic Medicine and Infectious Diseases, Department of Medicine, Tufts New England Medical Center, Boston, MA, USA
    Clin Infect Dis 42:836-42. 2006
    ..This information is intended to raise awareness among health care providers of HIV-infected patients that weight loss and wasting remain important acquired immunodeficiency syndrome-defining conditions, despite the advent of HAART...
  24. pmc Regional adipose tissue and lipid and lipoprotein levels in HIV-infected women
    Judith Currier
    Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA
    J Acquir Immune Defic Syndr 48:35-43. 2008
    ..HIV infection and antiretroviral therapy are associated with dyslipidemia, but the association between regional body fat and lipid levels is not well described...
  25. ncbi request reprint Parasitic sinusitis and otitis in patients infected with human immunodeficiency virus: report of five cases and review
    V A Dunand
    Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Clin Infect Dis 25:267-72. 1997
    ..The general outcome for HIV-infected patients with parasitic sinusitis and otitis was poor; however, deaths were generally associated with other complications of the underlying HIV infection...
  26. ncbi request reprint Successful treatment of diarrheal disease associated with enteroaggregative Escherichia coli in adults infected with human immunodeficiency virus
    C A Wanke
    Department of Medicine, Division of Infectious Diseases, Beth Israel Deaconess Medical Center, New England, USA
    J Infect Dis 178:1369-72. 1998
    ..It is likely that EAggEc are a treatable cause of diarrheal disease in some persons with HIV and no other apparent enteric pathogen...
  27. doi request reprint Comparison of standard PCR/cloning to single genome sequencing for analysis of HIV-1 populations
    Michael R Jordan
    Tufts University School of Medicine, Tufts Medical Center, Boston, MA 02111, USA
    J Virol Methods 168:114-20. 2010
    ....
  28. ncbi request reprint Use of recombinant human growth hormone in HIV-associated lipodystrophy
    Elizabeth Burgess
    Division of Nutrition and Infection, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Curr Opin Infect Dis 18:17-24. 2005
    ..This review examines the studies that have focused on the effects of recombinant human growth hormone as a treatment for the central fat accumulation that is part of this syndrome...
  29. pmc Circulating Nef induces dyslipidemia in simian immunodeficiency virus-infected macaques by suppressing cholesterol efflux
    Bela F Asztalos
    Lipid Metabolism Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA
    J Infect Dis 202:614-23. 2010
    ..These results indicate that SIV infection is a significant contributor to primary dyslipidemia, likely through the ability of Nef to suppress ABCA1-dependent reverse cholesterol transport...
  30. pmc HIV-1 seroprevalence and awareness of mother-to-child transmission issues among women seeking antenatal care in Tamil Nadu, India
    Jacqueline Firth
    Department of Medicine, Warren Alpert Medical School at Brown University, Providence, RI, USA
    J Int Assoc Physicians AIDS Care (Chic) 9:206-13. 2010
    ..Conclusions: There is a need to educate South Indian women about HIV to give them information and the means to protect themselves and their unborn children from acquiring HIV...
  31. ncbi request reprint Management of HIV wasting syndrome: a consensus conference
    Donald Kotler
    Section of GI Immunology, HIV Clinical and Research Program, St Luke s Roosevelt Hospital Center, Department of Medicine, Columbia College of Physicians and Surgeons, New York, NY, USA
    J Acquir Immune Defic Syndr 37:S261. 2004
  32. doi request reprint Drug use and other risk factors related to lower body mass index among HIV-infected individuals
    Lien A Quach
    Tufts University School of Medicine, Boston, MA 02111, USA
    Drug Alcohol Depend 95:30-6. 2008
    ..BMI was also directly associated with CD4 count and inversely related to age more than 55 years old. HIV-infected cocaine users may be at higher risk of developing malnutrition, suggesting the need for anticipatory nutritional support...
  33. ncbi request reprint High-fiber diet in HIV-positive men is associated with lower risk of developing fat deposition
    Kristy M Hendricks
    Department of Community Health and Family Medicine, Tufts University School of Medicine, Boston, MA 02111, USA
    Am J Clin Nutr 78:790-5. 2003
    ..Lipodystrophy has been described with increasing frequency in patients infected with HIV. This study focused on the identification of dietary components that may predispose HIV-positive patients to the development of fat deposition...
  34. ncbi request reprint Risk of cardiovascular disease in a cohort of HIV-infected adults: a study using carotid intima-media thickness and coronary artery calcium score
    Alexandra Mangili
    Department of Medicine, Tufts New England Medical Center, Boston, MA 02111, USA
    Clin Infect Dis 43:1482-9. 2006
    ..We measured 2 surrogate markers of subclinical atherosclerosis, carotid intima-media thickness (c-IMT) and coronary artery calcium (CAC) scores, in HIV-infected adults...
  35. ncbi request reprint Dietary glycemic index of human immunodeficiency virus-positive men with and without fat deposition
    Kimberly R Dong
    Department of Public Health and Family Medicine, Tufts University School of Medicine, Boston, MA 02111, USA
    J Am Diet Assoc 106:728-32. 2006
    ..Instead, results of this study depict the potential benefits associated with eating high-quality diets, primarily adequate fiber and protein intake. Diet can be important in preventing development of fat deposition in patients with HIV...
  36. ncbi request reprint Understanding the role of HIV load in determining weight change in the era of highly active antiretroviral therapy
    D Mkaya Mwamburi
    Division of Geographic Medicine and Infectious Diseases, Tufts New England Medical Center, Boston, MA 02111, USA
    Clin Infect Dis 40:167-73. 2005
    ..In this prospective cohort study, we determined the relationship between human immunodeficiency virus (HIV) RNA load and body weight in patients with HIV infection...
  37. ncbi request reprint Body composition in adults infected with human immunodeficiency virus in Khon Kaen, Thailand
    Mary Jon Ludy
    Frances Stern Nutrition Center, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Am J Trop Med Hyg 73:815-9. 2005
    ..86) and the lowest between BIA and triceps skinfold (r = 0.54). Insights were gained about relative value of using various measurements to assess nutritional status of HIV-infected populations...
  38. ncbi request reprint Predicting CD4 count using total lymphocyte count: a sustainable tool for clinical decisions during HAART use
    D Mkaya Mwamburi
    Division of Geographic Medicine and Infectious Diseases, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Am J Trop Med Hyg 73:58-62. 2005
    ..Including the additional factors improves performance. TLC is simple and inexpensive and can be used in many ways to develop clinical decision-making tools in underserved resource-poor settings during HAART therapy...
  39. ncbi request reprint Dietary supplement use and nutrient intake in HIV-infected persons
    Kristy M Hendricks
    Department of Public Health and Family Medicine, Tufts University School of Medicine, Boston, Massachusetts, USA
    AIDS Read 17:211-6, 223-7. 2007
    ..Micronutrient inadequacy and excess are relatively common in persons living with HIV infection. Practitioners need to judiciously address optimal nutrient intake from both diet and dietary supplements in this population...
  40. pmc Metabolic syndrome and subclinical atherosclerosis in patients infected with HIV
    Alexandra Mangili
    Department of Medicine, Tufts New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Clin Infect Dis 44:1368-74. 2007
    ..The present study examines the association between carotid and coronary atherosclerosis and metabolic syndrome in human immunodeficiency virus (HIV)-infected adults...
  41. ncbi request reprint Comparing megestrol acetate therapy with oxandrolone therapy for HIV-related weight loss: similar results in 2 months
    D Mkaya Mwamburi
    Division of Geographic Medicine and Infectious Diseases, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Clin Infect Dis 38:895-902. 2004
    ..74). In conclusion, megestrol acetate therapy and oxandrolone therapy have similar effects on body weight and composition and are safe and well-tolerated during HAART...
  42. pmc Multilocus genotyping of Cryptosporidium sp. isolates from human immunodeficiency virus-infected individuals in South India
    Dheepa Muthusamy
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, 632004, India
    J Clin Microbiol 44:632-4. 2006
    ..meleagridis were identified. Cpgp40/15 PCR-restriction fragment length polymorphism identified six subgenotypes. Cryptosporidial diarrhea was associated with decreased CD4 counts, below 200 (P = 0.009), but not high viral loads...
  43. ncbi request reprint Analysis of generic antiretroviral formulations manufactured in India
    Geetha Ramachandran
    AIDS 18:1482-4. 2004
  44. doi request reprint Screening and assessment of coronary heart disease in HIV-infected patients
    Priscilla Y Hsue
    Circulation 118:e41-7. 2008

Research Grants17

  1. Nutrition and HIV Progression
    Christine A Wanke; Fiscal Year: 2010
    ..We propose to collect data on 200 women who are documented to be HIV-negative from Voi Division at a single visit, the Division that will also provide the HIV -infected women for the intervention study. ..
  2. NEMCH CLINICAL RESEARCH ON AIDS TRAINING GRANT
    Christine Wanke; Fiscal Year: 2007
    ....
  3. The Impact of Omega three Fatty Acids on Vascular Function and cIMT in HIV
    Christine A Wanke; Fiscal Year: 2010
    ....
  4. PROTEASE INHIBITOR RELATED DYSLIPIDEMIA
    Christine A Wanke; Fiscal Year: 2010
    ..The longitudinal determination of HDL subpopulations, the simultaneous determination of both cIMT and coronary calcium scores at 6 years in an HIV infected cohort are novel to this project. ..
  5. The Impact of Omega three Fatty Acids on Vascular Function and cIMT in HIV
    Christine Wanke; Fiscal Year: 2009
    ....
  6. PROTEASE INHIBITOR RELATED DYSLIPIDEMIA
    Christine Wanke; Fiscal Year: 2009
    ..The longitudinal determination of HDL subpopulations, the simultaneous determination of both cIMT and coronary calcium scores at 6 years in an HIV infected cohort are novel to this project. ..
  7. PROTEASE INHIBITOR RELATED DYSLIPIDEMIA
    Christine Wanke; Fiscal Year: 2007
    ..The longitudinal determination of HDL subpopulations, the simultaneous determination of both cIMT and coronary calcium scores at 6 years in an HIV infected cohort are novel to this project. ..
  8. MIDCAREER INVESTIGATOR AWARD IN PATIENT ORIENTED RESEA
    Christine Wanke; Fiscal Year: 2007
    ..I hope to be able to work toward some elucidation of these issues with the support of this award. In addition, this award will support my ability to mentor trainees in these important clinical research questions. ..
  9. Feasibility Study of Probiotics for Growth Faltering
    Christine Wanke; Fiscal Year: 2006
    ..These data will be used, with the feasibility data obtained, to prepare a proposal for a full clinical trial of LGG as an intervention for growth faltering and diarrheal disease at the time of weaning in these children. ..
  10. PROTEASE INHIBITOR RELATED DYSLIPIDEMIA
    Christine Wanke; Fiscal Year: 2004
    ..This research should define the nature of the problem, its mechanism, and methods for treatment wit regard to the hyperlipidemia induced by protease inhibitors in HIV patients. ..