Katherine Tucker

Summary

Affiliation: Tufts University
Country: USA

Publications

  1. ncbi Osteoporosis prevention and nutrition
    Katherine L Tucker
    USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Curr Osteoporos Rep 7:111-7. 2009
  2. pmc Disparities in allele frequencies and population differentiation for 101 disease-associated single nucleotide polymorphisms between Puerto Ricans and non-Hispanic whites
    Josiemer Mattei
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
    BMC Genet 10:45. 2009
  3. ncbi Assessment of usual dietary intake in population studies of gene-diet interaction
    Katherine L Tucker
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Nutr Metab Cardiovasc Dis 17:74-81. 2007
  4. ncbi Colas, but not other carbonated beverages, are associated with low bone mineral density in older women: The Framingham Osteoporosis Study
    Katherine L Tucker
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 84:936-42. 2006
  5. ncbi High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study
    Katherine L Tucker
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 82:627-35. 2005
  6. ncbi Dietary intake and bone status with aging
    Katherine L Tucker
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington St, Boston, MA 02111, USA
    Curr Pharm Des 9:2687-704. 2003
  7. ncbi Commentary: Dietary patterns in transition can inform health risk, but detailed assessments are needed to guide recommendations
    Katherine Tucker
    Dietary Assessment and Epidemiology Research Program, Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Int J Epidemiol 36:610-1. 2007
  8. ncbi A regional food-frequency questionnaire for the US Mississippi Delta
    Katherine L Tucker
    Jean Mayer US Department of Agriculture USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Public Health Nutr 8:87-96. 2005
  9. ncbi Low plasma vitamin B12 is associated with lower BMD: the Framingham Osteoporosis Study
    Katherine L Tucker
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    J Bone Miner Res 20:152-8. 2005
  10. ncbi Breakfast cereal fortified with folic acid, vitamin B-6, and vitamin B-12 increases vitamin concentrations and reduces homocysteine concentrations: a randomized trial
    Katherine L Tucker
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Am J Clin Nutr 79:805-11. 2004

Research Grants

Detail Information

Publications89

  1. ncbi Osteoporosis prevention and nutrition
    Katherine L Tucker
    USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Curr Osteoporos Rep 7:111-7. 2009
    ..Current research on diet and bone status supports encouragement of balanced diets with plenty of fruit and vegetables, adequate dairy and other protein foods, and limitation of foods with low nutrient density...
  2. pmc Disparities in allele frequencies and population differentiation for 101 disease-associated single nucleotide polymorphisms between Puerto Ricans and non-Hispanic whites
    Josiemer Mattei
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
    BMC Genet 10:45. 2009
    ....
  3. ncbi Assessment of usual dietary intake in population studies of gene-diet interaction
    Katherine L Tucker
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Nutr Metab Cardiovasc Dis 17:74-81. 2007
    ..Dietary intake is a critical environmental exposure when considering the effect of many genetic factors on disease risk. However, dietary intake is a complex and changing measure that requires particular care in assessment...
  4. ncbi Colas, but not other carbonated beverages, are associated with low bone mineral density in older women: The Framingham Osteoporosis Study
    Katherine L Tucker
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 84:936-42. 2006
    ..In addition to displacing healthier beverages, colas contain caffeine and phosphoric acid (H3PO4), which may adversely affect bone...
  5. ncbi High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study
    Katherine L Tucker
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 82:627-35. 2005
    ..It is not clear whether the observed associations between homocysteine and cognitive measures are causal or whether they are due to homocysteine, to independent actions of the B vitamins, or to both...
  6. ncbi Dietary intake and bone status with aging
    Katherine L Tucker
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington St, Boston, MA 02111, USA
    Curr Pharm Des 9:2687-704. 2003
    ..With advances in both genetics and nutrition, improved understanding of all these interactions will contribute to effective recommendations for prevention of bone loss and osteoporosis in the aging population...
  7. ncbi Commentary: Dietary patterns in transition can inform health risk, but detailed assessments are needed to guide recommendations
    Katherine Tucker
    Dietary Assessment and Epidemiology Research Program, Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Int J Epidemiol 36:610-1. 2007
  8. ncbi A regional food-frequency questionnaire for the US Mississippi Delta
    Katherine L Tucker
    Jean Mayer US Department of Agriculture USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Public Health Nutr 8:87-96. 2005
    ....
  9. ncbi Low plasma vitamin B12 is associated with lower BMD: the Framingham Osteoporosis Study
    Katherine L Tucker
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    J Bone Miner Res 20:152-8. 2005
    ..Men with plasma B12 < 148 pM had significantly lower BMD at the hip, and women at the spine, relative to those with higher B12, and trends were similar for both at all sites. Low vitamin B12 may be a risk factor for low BMD...
  10. ncbi Breakfast cereal fortified with folic acid, vitamin B-6, and vitamin B-12 increases vitamin concentrations and reduces homocysteine concentrations: a randomized trial
    Katherine L Tucker
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Am J Clin Nutr 79:805-11. 2004
    ..High homocysteine and low B vitamin concentrations have been linked to the risk of vascular disease, stroke, and dementia and are relatively common in older adults...
  11. pmc Effects of beer, wine, and liquor intakes on bone mineral density in older men and women
    Katherine L Tucker
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 89:1188-96. 2009
    ..Moderate intake of alcohol has been reported to have beneficial effects on bone. However, different classes of alcoholic beverages have not been investigated...
  12. ncbi Assessing dietary intake of drug-abusing Hispanic adults with and without human immunodeficiency virus infection
    Shivani Sahni
    Jean Mayer US Department of Agriculture, Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111 1524, USA
    J Am Diet Assoc 107:968-76. 2007
    ..The selection of a dietary assessment method most appropriate for Hispanic adults with/without HIV infection who may be drug abusers remains unclear...
  13. ncbi Associations of empirically derived eating patterns with plasma lipid biomarkers: a comparison of factor and cluster analysis methods
    P K Newby
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Am J Clin Nutr 80:759-67. 2004
    ..Despite the growing use of patterning methods in nutritional epidemiology, a direct comparison of factor and cluster analysis methods has not been performed...
  14. ncbi Dietary factors associated with the risk of high iron stores in the elderly Framingham Heart Study cohort
    Diana J Fleming
    Mineral Bioavailability Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 76:1375-84. 2002
    ..High body iron stores may increase the risk of several chronic diseases. Whether dietary factors contribute to the risk of high iron stores is unknown...
  15. pmc Inverse association of carotenoid intakes with 4-y change in bone mineral density in elderly men and women: the Framingham Osteoporosis Study
    Shivani Sahni
    Dietary Assessment and Epidemiology Research Program and the Antioxidants Research Laboratory, Jean Mayer US Department of Agriculture, HNRCA, Tufts University, Boston, MA 02111 1524, USA
    Am J Clin Nutr 89:416-24. 2009
    ..Few studies have examined the association between carotenoid intake (other than beta-carotene) and bone mineral density (BMD)...
  16. pmc APOA2, dietary fat, and body mass index: replication of a gene-diet interaction in 3 independent populations
    Dolores Corella
    Nutrition and Genomics Laboratory, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, 711 Washington St, Boston, MA 02111 1524, USA
    Arch Intern Med 169:1897-906. 2009
    ..However, replication has been low. Our aim was to study interaction among a functional APOA2 polymorphism, food intake, and body mass index (BMI) in independent populations to replicate findings and to increase their evidence level...
  17. pmc Association between glucokinase regulatory protein (GCKR) and apolipoprotein A5 (APOA5) gene polymorphisms and triacylglycerol concentrations in fasting, postprandial, and fenofibrate-treated states
    Pablo Perez-Martinez
    Nutrition and Genomics Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    Am J Clin Nutr 89:391-9. 2009
    ..Hypertriglyceridemia is a risk factor for cardiovascular disease. Variation in the apolipoprotein A5 (APOA5) and glucokinase regulatory protein (GCKR) genes has been associated with fasting plasma triacylglycerol...
  18. pmc Intake of whole grains, refined grains, and cereal fiber measured with 7-d diet records and associations with risk factors for chronic disease
    P K Newby
    Department of Pediatrics, Boston University School of Medicine, Boston Medical Center, Boston, MA 02118, USA
    Am J Clin Nutr 86:1745-53. 2007
    ..Single-nutrient studies are also needed to explore the mechanisms by which foods may be protective...
  19. pmc Serum carotenoid and tocopherol concentrations vary by dietary pattern among African Americans
    Sameera A Talegawkar
    Tufts University, Boston, MA, USA
    J Am Diet Assoc 108:2013-20. 2008
    ..Intakes and biochemical concentrations of carotenoids and tocopherols have been associated with chronic diseases...
  20. ncbi Higher dietary variety is associated with better nutritional status in frail elderly people
    Melissa A Bernstein
    Gerald J and Dorothy R Friedman School of Nutrition Science and Policy, Tufts University, USA
    J Am Diet Assoc 102:1096-104. 2002
    ..A narrow range of food choices may lead to dietary inadequacies, a particular concern in elderly people. We hypothesized that consumption of a more diverse diet would predict better nutritional status in frail elderly persons...
  21. pmc Apolipoprotein A5 and lipoprotein lipase interact to modulate anthropometric measures in Hispanics of Caribbean origin
    Caren E Smith
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA
    Obesity (Silver Spring) 18:327-32. 2010
    ..Analyses of gene-gene interactions may improve understanding of genetically based obesity risk, and underscore the need for further study of groups with multiple ancestral admixtures...
  22. ncbi alpha-Tocopherol intake and plasma concentration of Hispanic and non-Hispanic white elders is associated with dietary intake pattern
    Xiang Gao
    The Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Nutr 136:2574-9. 2006
    ..05 for all), although they had similar intakes. A large proportion of these elders (>90%) have inadequate intake of alpha-tocopherol, and plasma concentrations were associated with intake patterns...
  23. ncbi Longitudinal changes in food patterns predict changes in weight and body mass index and the effects are greatest in obese women
    P K Newby
    The Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Nutr 136:2580-7. 2006
    ..Pattern analysis is helpful in generating hypotheses regarding the role of diet in obesity, and additional research is needed to understand which elements of our patterns are protective or risk factors for weight gain...
  24. pmc WDTC1, the ortholog of Drosophila adipose gene, associates with human obesity, modulated by MUFA intake
    Chao Qiang Lai
    JM USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts, USA
    Obesity (Silver Spring) 17:593-600. 2009
    ..Given the high frequency of the major alleles in both populations, we suggest that WDTC1 variation may be an important risk factor contributing to obesity in these populations...
  25. pmc Apolipoprotein A5 polymorphisms interact with total dietary fat intake in association with markers of metabolic syndrome in Puerto Rican older adults
    Josiemer Mattei
    Jean Mayer USDA Human Nutrition Research Center on Aging, Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA
    J Nutr 139:2301-8. 2009
    ..Dietary fat intake seems to modulate these associations. The results contribute to the understanding of health disparities in this population...
  26. ncbi Plasma C-reactive protein and homocysteine concentrations are related to frequent fruit and vegetable intake in Hispanic and non-Hispanic white elders
    Xiang Gao
    The Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Nutr 134:913-8. 2004
    ..Because both of these metabolites are known risk factors for CVD, these findings contribute to the evidence that a higher intake of fruit and vegetables may reduce the risk of CVD...
  27. pmc Polymorphisms in uracil-processing genes, but not one-carbon nutrients, are associated with altered DNA uracil concentrations in an urban Puerto Rican population
    Aurelie Chanson
    Jean Mayer US Department of Agriculture, Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 89:1927-36. 2009
    ..Because of their metabolic function, folate and other one-carbon micronutrients may be important factors in the control of uracil misincorporation...
  28. pmc Vitamin B6 is associated with depressive symptomatology in Massachusetts elders
    CRISTINA MERETE
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Am Coll Nutr 27:421-7. 2008
    ....
  29. ncbi The maximal amount of dietary alpha-tocopherol intake in U.S. adults (NHANES 2001-2002)
    Xiang Gao
    The Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
    J Nutr 136:1021-6. 2006
    ..Careful selection of the highest vitamin E source foods within these groups could further increase the likelihood of meeting the current recommended daily allowance...
  30. pmc A traditional rice and beans pattern is associated with metabolic syndrome in Puerto Rican older adults
    Sabrina E Noel
    USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Nutr 139:1360-7. 2009
    ..8, 95% CI: 1.03, 3.3). Dietary patterns were significantly associated with metabolic syndrome and its components. More research is needed to make appropriate nutritional recommendations for this high-risk population...
  31. ncbi Dietary and nondietary determinants of vitamin K biochemical measures in men and women
    Nicola M McKeown
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Nutr 132:1329-34. 2002
    ..Despite these caveats, these findings support the use of a FFQ for a relative assessment of vitamin K status in population-based studies...
  32. ncbi The 2005 USDA Food Guide Pyramid is associated with more adequate nutrient intakes within energy constraints than the 1992 Pyramid
    Xiang Gao
    Harvard School of Public Health, Boston, MA, USA
    J Nutr 136:1341-6. 2006
    ..Our analysis suggests that following the 2005 FGP may be associated with lower energy and optimal nutrient intake. Careful restriction of discretionary calories appears necessary for appropriate energy intakes to be maintained...
  33. pmc Carotenoid intakes, assessed by food-frequency questionnaires (FFQs), are associated with serum carotenoid concentrations in the Jackson Heart Study: validation of the Jackson Heart Study Delta NIRI Adult FFQs
    Sameera A Talegawkar
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Public Health Nutr 11:989-97. 2008
    ....
  34. pmc Allostatic load is associated with chronic conditions in the Boston Puerto Rican Health Study
    Josiemer Mattei
    Tufts University, Boston, MA, USA
    Soc Sci Med 70:1988-96. 2010
    ..These results have prospective research implications for Puerto Ricans and other ethnic groups...
  35. ncbi Polyunsaturated fatty acids interact with the PPARA-L162V polymorphism to affect plasma triglyceride and apolipoprotein C-III concentrations in the Framingham Heart Study
    E Shyong Tai
    Nutrition and Genomics Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111 1524, USA
    J Nutr 135:397-403. 2005
    ..Our data show that the effect of the L162V polymorphism on plasma TG and apoC-III concentrations depends on the dietary PUFA, with a high intake triggering lower TG in carriers of the 162V allele...
  36. ncbi Intake of added sugar and sugar-sweetened drink and serum uric acid concentration in US men and women
    Xiang Gao
    Department of Nutrition, Harvard University School of Public Health, Boston, MA 02115, USA
    Hypertension 50:306-12. 2007
    ..2; P for interaction <0.01). Further research is needed to confirm causality of these associations and the observed difference by gender...
  37. ncbi A home-based nutrition intervention to increase consumption of fruits, vegetables, and calcium-rich foods in community dwelling elders
    A Bernstein
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Am Diet Assoc 102:1421-7. 2002
    ..To increase fruit, vegetable, and calcium-rich food consumption in community-dwelling, functionally impaired elderly...
  38. pmc Population admixture associated with disease prevalence in the Boston Puerto Rican health study
    Chao Qiang Lai
    Nutrition and Genomics Laboratory, JM USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington St, Boston, MA 02111, USA
    Hum Genet 125:199-209. 2009
    ....
  39. ncbi APOA5 gene variation modulates the effects of dietary fat intake on body mass index and obesity risk in the Framingham Heart Study
    Dolores Corella
    Nutrition and Genomics Laboratory, JM USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111 1524, USA
    J Mol Med (Berl) 85:119-28. 2007
    ..In conclusion, the APOA5-1131T>C SNP, which is present in approximately 13% of this population, modulates the effect of fat intake on BMI and obesity risk in both men and women...
  40. ncbi Low vitamin B-12 intake and status are more prevalent in Hispanic older adults of Caribbean origin than in neighborhood-matched non-Hispanic whites
    Laurinda L Kwan
    The Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Nutr 132:2059-64. 2002
    ..As in other populations, sources of unbound vitamin B-12 such as supplements and fortified cereal appear to be protective. Dietary intervention programs targeted to the Hispanic population should promote these vitamin B-12 sources...
  41. pmc Validity of estimated dietary eicosapentaenoic acid and docosahexaenoic acid intakes determined by interviewer-administered food frequency questionnaire among older adults with mild-to-moderate cognitive impairment or dementia
    Lisa N Arsenault
    Tufts University, Boston, Massachusetts 02124, USA
    Am J Epidemiol 170:95-103. 2009
    ..This frequency was consistently high across all cognitive categories. With interviewer administration, this FFQ seems to be a valid method of assessing dietary EPA + DHA intake in older adults with mild-to-moderate cognitive impairment...
  42. ncbi Dietary pattern is associated with homocysteine and B vitamin status in an urban Chinese population
    Xiang Gao
    The Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Nutr 133:3636-42. 2003
    ..Dietary patterns appear to play an important role in the micronutrient and homocysteine status of these Chinese adults...
  43. ncbi High intra/interindividual variance ratios for energy and nutrient intakes of pregnant women in rural Malawi show that many days are required to estimate usual intake
    Joshua Nyambose
    School of Nutrition Science and Policy, the Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging HNRCA, Tufts University, Boston, MA 02111, USA
    J Nutr 132:1313-8. 2002
    ....
  44. pmc MAT1A variants are associated with hypertension, stroke, and markers of DNA damage and are modulated by plasma vitamin B-6 and folate
    Chao Qiang Lai
    Nutrition and Genomics Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 91:1377-86. 2010
    ..The S-adenosylmethionine synthetase type 1 (MAT1A) gene encodes a key enzyme in one-carbon nutrient metabolism...
  45. doi Air pollution and homocysteine: more evidence that oxidative stress-related genes modify effects of particulate air pollution
    Cizao Ren
    Exposure, Epidemiology, and Risk Program, Harvard School of Public Health, Boston, MA 02215, USA
    Epidemiology 21:198-206. 2010
    ..nondeletion), and HMOX-1 (any short vs. both long). We attempted to replicate identified genes in an analysis of heart rate variability and in other outcomes reported in the literature...
  46. pmc Poor iron status is more prevalent in Hispanic than in non-Hispanic white older adults in Massachusetts
    Erin L Seaverson
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Nutr 137:414-20. 2007
    ..Cultural variation in dietary patterns may influence iron availability and body iron stores and contribute to an increased risk for iron deficiency anemia among some Hispanic older adults...
  47. ncbi Meeting adequate intake for dietary calcium without dairy foods in adolescents aged 9 to 18 years (National Health and Nutrition Examination Survey 2001-2002)
    Xiang Gao
    Department of Nutrition, Harvard University School of Public Health, Boston, MA 02111, USA
    J Am Diet Assoc 106:1759-65. 2006
    ..However, no studies have addressed whether dairy-free diets can provide adequate calcium while meeting other nutrient recommendations...
  48. ncbi Association of a common polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene with bone phenotypes depends on plasma folate status
    Robert R McLean
    Research and Training Institute, Hebrew Rehabilitation Center for Aged, Boston, Massachusetts 01702, USA
    J Bone Miner Res 19:410-8. 2004
    ..Our findings support the hypothesis that the association between an MTHFR polymorphism and bone phenotypes depends on folate status...
  49. pmc Association of vitamin B-6 status with inflammation, oxidative stress, and chronic inflammatory conditions: the Boston Puerto Rican Health Study
    Jian Shen
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111 1524, USA
    Am J Clin Nutr 91:337-42. 2010
    ..Low vitamin B-6 status has been linked to an increased risk of cardiovascular diseases. The cardioprotective effects of vitamin B-6 independent of homocysteine suggest that additional mechanisms may be involved...
  50. pmc High vitamin C intake is associated with lower 4-year bone loss in elderly men
    Shivani Sahni
    Dietary Assessment and Epidemiology Research Program, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Nutr 138:1931-8. 2008
    ..Null associations were observed among women. These results suggest a possible protective role of vitamin C for bone health in older men...
  51. ncbi Diet and risk of adult glioma in eastern Nebraska, United States
    Honglei Chen
    Tufts University, Human Nutrition Research Center on Aging, Boston, MA, USA
    Cancer Causes Control 13:647-55. 2002
    ..To investigate potential associations between diet and adult glioma...
  52. ncbi Dietary patterns of Hispanic elders are associated with acculturation and obesity
    Hai Lin
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Nutr 133:3651-7. 2003
    ..Total and central obesity were positively associated with the rice pattern. Longitudinal studies are needed to clarify the causal nature of these associations...
  53. ncbi Long-term stability of food patterns identified by use of factor analysis among Swedish women
    P K Newby
    Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Nutr 136:626-33. 2006
    ..Testing whether patterns measured over a long time period can be used in analytic studies is the next step in assessing the validity of this method...
  54. ncbi Relative influence of diet and physical activity on body composition in urban Chinese adults
    Manjiang Yao
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 77:1409-16. 2003
    ..The relative influence of diet and physical activity on body fatness remains uncertain...
  55. ncbi The combination of high fruit and vegetable and low saturated fat intakes is more protective against mortality in aging men than is either alone: the Baltimore Longitudinal Study of Aging
    Katherine L Tucker
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
    J Nutr 135:556-61. 2005
    ..In addition, they extend these findings by demonstrating that the combination of both behaviors is more protective than either alone, suggesting that their beneficial effects are mediated by different mechanisms...
  56. ncbi Hispanic and non-Hispanic white elders from Massachusetts have different patterns of carotenoid intake and plasma concentrations
    Odilia I Bermudez
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Nutr 135:1496-502. 2005
    ..Because of the potential importance of carotenoids as protective factors against chronic diseases, more attention to food-related practices associated with carotenoid intake in differing population groups is warranted...
  57. ncbi The effect of drug abuse on body mass index in Hispanics with and without HIV infection
    Janet E Forrester
    Department of Family Medicine and Community Health, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA
    Public Health Nutr 8:61-8. 2005
    ..The purpose of this study was to examine non-dietary factors that could affect the weight of drug abusers with and without HIV infection...
  58. ncbi Stress and nutrition in relation to excess development of chronic disease in Puerto Rican adults living in the Northeastern USA
    Katherine L Tucker
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111 1524, USA
    J Med Invest 52:252-8. 2005
    ..We further propose that the association between life stress, physiologic response and chronic conditions is modified by nutritional status, with a focus on B vitamins and antioxidant vitamins...
  59. ncbi A randomized controlled trial of resistance exercise training to improve glycemic control in older adults with type 2 diabetes
    Carmen Castaneda
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    Diabetes Care 25:2335-41. 2002
    ..To determine the efficacy of high-intensity progressive resistance training (PRT) on glycemic control in older adults with type 2 diabetes...
  60. doi Intake of lutein and zeaxanthin differ with age, sex, and ethnicity
    Elizabeth J Johnson
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Am Diet Assoc 110:1357-62. 2010
    ..Our findings suggest that the relative intake of lutein and zeaxanthin may be important to age-related macular degeneration risk. Future studies are needed to assess the individual associations of lutein and zeaxanthin in eye health...
  61. pmc Plasma B vitamins, homocysteine, and their relation with bone loss and hip fracture in elderly men and women
    Robert R McLean
    Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, Boston, MA 02131, USA
    J Clin Endocrinol Metab 93:2206-12. 2008
    ..Elevated homocysteine is a strong risk factor for osteoporotic fractures among elders, yet it may be a marker for low B-vitamin status...
  62. ncbi Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: the Framingham Heart Study
    Ernst J Schaefer
    Lipid Metabolism Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tuffs University, Boston, MA 02111, USA
    Arch Neurol 63:1545-50. 2006
    ..Docosahexaenoic acid (DHA) is an abundant fatty acid in the brain. In the diet, DHA is found mostly in fatty fish. The content of DHA has been shown to be decreased in the brain and plasma of patients with dementia...
  63. doi Dietary patterns, approaches, and multicultural perspective
    Katherine L Tucker
    Department of Health Sciences, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA
    Appl Physiol Nutr Metab 35:211-8. 2010
    ..Still, dietary pattern research has great potential for use in nutrition policy, particularly as it demonstrates the importance of total diet in health promotion...
  64. ncbi Television viewing is associated with prevalence of metabolic syndrome in Hispanic elders
    Xiang Gao
    Jean Mayer USDA HNRCA at Tufts University, 711 Washington St, Boston, MA 02111 1524, USA
    Diabetes Care 30:694-700. 2007
    ..We examined associations between television viewing and prevalence of the metabolic syndrome among a representative sample of Caribbean-origin Hispanic elders living in Massachusetts...
  65. ncbi Homocysteine as a predictive factor for hip fracture in older persons
    Robert R McLean
    Hebrew Rehabilitation Center for Aged Research and Training Institute, Boston, USA
    N Engl J Med 350:2042-9. 2004
    ..We examined the association between the total homocysteine concentration and the risk of hip fracture in men and women enrolled in the Framingham Study...
  66. pmc Residential traffic exposure, pulse pressure, and C-reactive protein: consistency and contrast among exposure characterization methods
    Christine L Rioux
    Department of Public Health and Community Medicine, Tufts University, Boston, Massachusetts 02155, USA
    Environ Health Perspect 118:803-11. 2010
    ..Traffic exposure may increase cardiovascular disease (CVD) risk via systemic inflammation and elevated blood pressure, two important clinical markers for managing disease progression...
  67. ncbi Dietary and plasma lipid, lipoprotein, and apolipoprotein profiles among elderly Hispanics and non-Hispanics and their association with diabetes
    Odilia I Bermudez
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 76:1214-21. 2002
    ..There are limited data about dietary intakes and plasma lipids of elderly US Hispanics...
  68. ncbi Dietary fat intake determines the effect of a common polymorphism in the hepatic lipase gene promoter on high-density lipoprotein metabolism: evidence of a strong dose effect in this gene-nutrient interaction in the Framingham Study
    Jose M Ordovas
    Nutrition and Genomics Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, Mass 02111, USA
    Circulation 106:2315-21. 2002
    ..This allele has been associated with decreased HL activity and increased HDL-C concentrations. However, the effect is variable among populations...
  69. ncbi Vitamin K intake and bone mineral density in women and men
    Sarah L Booth
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 77:512-6. 2003
    ..Low dietary vitamin K intake has been associated with an increased risk of hip fracture in men and women. Few data exist on the association between dietary vitamin K intake and bone mineral density (BMD)...
  70. ncbi Trends in dietary patterns of Latin American populations
    Odilia I Bermudez
    Jean Mayer U S Department of Agriculture, Human Nutrition Research Center on Aging, Tufts University, Boston, MA, 02111 1524, USA
    Cad Saude Publica 19:S87-99. 2003
    ..Efforts to educate the population on the importance of a healthy diet and to issue policies to improve the availability of a healthy food supply can help to reduce the rapid escalation of obesity and chronic diseases...
  71. ncbi Dietary intake of n-6 fatty acids modulates effect of apolipoprotein A5 gene on plasma fasting triglycerides, remnant lipoprotein concentrations, and lipoprotein particle size: the Framingham Heart Study
    Chao Qiang Lai
    Nutrition and Genomics Laboratory, JM USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Circulation 113:2062-70. 2006
    ..Apolipoprotein A5 gene (APOA5) variation is associated with plasma triglycerides (TGs). However, little is known about whether dietary fat modulates this association...
  72. ncbi Bone mineral density and dietary patterns in older adults: the Framingham Osteoporosis Study
    Katherine L Tucker
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 76:245-52. 2002
    ..Several nutrients are known to affect bone mineral density (BMD). However, these nutrients occur together in foods and dietary patterns, and the overall effects of dietary choices are not well understood...
  73. ncbi Dietary intake and body mass index in HIV-positive and HIV-negative drug abusers of Hispanic ethnicity
    Janet E Forrester
    Department of Familly Medicine and Community Health, Tufts University School of Medicine, Boston, MA 02111, USA
    Public Health Nutr 7:863-70. 2004
    ..Many studies have not considered possible concurrent HIV disease. The purpose of this study was to determine the relationship between drug abuse and dietary intake in Hispanic Americans with and without HIV infection...
  74. ncbi Polyunsaturated fatty acids modulate the effects of the APOA1 G-A polymorphism on HDL-cholesterol concentrations in a sex-specific manner: the Framingham Study
    Jose M Ordovas
    Nutrition and Genomics Laboratory, the Lipid Metabolism Laboratory and the Epidemiology Program, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston 02111, USA
    Am J Clin Nutr 75:38-46. 2002
    ..The A allele was shown to be associated with higher HDL-cholesterol concentrations in some studies but not in others...
  75. doi Social support, life events, and psychological distress among the Puerto Rican population in the Boston area of the United States
    Luis M Falcon
    Northeastern University, Boston, MA, USA
    Aging Ment Health 13:863-73. 2009
    ..The aim of this article is to investigate the role of social network support in ameliorating the psychological impact of life stressors that are prevalent for the older Puerto Rican population...
  76. pmc 25-Hydroxyvitamin D, dementia, and cerebrovascular pathology in elders receiving home services
    J S Buell
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington St, Boston, MA 02111, USA
    Neurology 74:18-26. 2010
    ..However, no studies have examined the association between vitamin D status, dementia, and cranial MRI indicators of cerebrovascular disease (CVD)...
  77. ncbi The maximal amount of alpha-tocopherol intake from foods alone in U.S. adults (1994-1996 CSFII): an analysis by linear programming
    Xiang Gao
    The Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Ann N Y Acad Sci 1031:385-6. 2004
  78. ncbi Nutritional, immunological and health status of the elderly population living in poor neighbourhoods of Quito, Ecuador
    Fernando Sempertegui
    Corporación Ecuatoriana de Biotecnología, Ave Colón 1468 y Nueve de Octubre Of 508, Quito, Ecuador
    Br J Nutr 96:845-53. 2006
    ..In conclusion, while few elderly Ecuadorians were underweight, obesity was common. Micronutrient deficiencies were prevalent and may contribute to reduced immunological responses in this population...
  79. ncbi Calcium intake and prostate cancer risk in a long-term aging study: the Baltimore Longitudinal Study of Aging
    Sonja I Berndt
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Urology 60:1118-23. 2002
    ..To investigate the association between prostate cancer and calcium and other nutrients thought to influence the synthesis of 1,25-dihydroxyvitamin D [1,25(OH)2D]...
  80. ncbi Food patterns measured by factor analysis and anthropometric changes in adults
    P K Newby
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, 9th Floor, Boston, MA 02111, USA
    Am J Clin Nutr 80:504-13. 2004
    ..Sixty-five percent of US adults are overweight, and 31% of these adults are obese. Obesity results from weight gains over time; however, dietary determinants of weight gain remain controversial...
  81. ncbi Hypertension among Hispanic elders of a Caribbean origin in Massachusetts
    Hai Lin
    Jean Mayer US Department of Agriculture, Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    Ethn Dis 12:499-507. 2002
    ..We determined the prevalence and associated risk factors of hypertension in Hispanic elders, ages 60-92 years, living in Massachusetts...
  82. ncbi A study of dietary patterns in the Mexican-American population and their association with obesity
    Patricia M Carrera
    Department of Nutrition, University of Maryland, College Park, USA
    J Am Diet Assoc 107:1735-42. 2007
    ..We hypothesized that Mexican-American adults following a traditional diet would have a lower prevalence of obesity than those following a more typical American diet...
  83. ncbi Association of energy intake with prostate cancer in a long-term aging study: Baltimore Longitudinal Study of Aging (United States)
    Lillian J Hsieh
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Urology 61:297-301. 2003
    ..To examine the association of total energy intake and macronutrient contributors to energy with prostate cancer risk among men in the Baltimore Longitudinal Study of Aging...
  84. ncbi Homocysteine and B vitamins relate to brain volume and white-matter changes in geriatric patients with psychiatric disorders
    Tammy Maria Scott
    Department of Psychiatry, Tufts New England Medical Center, and Tufts University School of Medicine, Boston, MA 02446, USA
    Am J Geriatr Psychiatry 12:631-8. 2004
    ..The authors examined the relationship of homocysteine, folate, and vitamin B12 with magnetic resonance imaging (MRI) markers of neuropathology...
  85. pmc Traffic-related particles are associated with elevated homocysteine: the VA normative aging study
    Sung Kyun Park
    Department of Environmental Health Sciences, University of Michigan School of Public Health, 109 S Observatory Street, SPH II M6240, Ann Arbor, MI 48109, USA
    Am J Respir Crit Care Med 178:283-9. 2008
    ..Particulate air pollution has been related to cardiovascular death and hospital admission, but the underlying mechanisms are not fully elucidated...
  86. ncbi Dietary silicon intake is positively associated with bone mineral density in men and premenopausal women of the Framingham Offspring cohort
    Ravin Jugdaohsingh
    Gastrointestinal Laboratory, The Rayne Institute, St Thomas Hospital, London, United Kingdom
    J Bone Miner Res 19:297-307. 2004
    ....
  87. ncbi Dietary behaviors, physical activity, and cigarette smoking among pregnant Puerto Rican women
    Audra Gollenberg
    Division of Biostatistics and Epidemiology, Department of Public Health, the School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA, USA
    Am J Clin Nutr 87:1844-51. 2008
    ..Few studies have examined predictors of meeting health guidelines in pregnancy among Latina women...
  88. pmc PPARG by dietary fat interaction influences bone mass in mice and humans
    Cheryl L Ackert-Bicknell
    The Jackson Laboratory, Bar Harbor, Maine 04609, USA
    J Bone Miner Res 23:1398-408. 2008
    ..These findings suggest that dietary fat has a significant influence on BMD that is dependent on the alleles present for the PPARG gene...
  89. ncbi Risk of overweight and obesity among semivegetarian, lactovegetarian, and vegan women
    P K Newby
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 81:1267-74. 2005
    ..Observational studies suggest that a plant-based diet is inversely related to body mass index (BMI), overweight, and obesity...

Research Grants3

  1. Nutrition, Stress and Bone in Older Puerto Ricans
    Katherine Tucker; Fiscal Year: 2007
    ....
  2. Center for Research/Nutrition & Health among the Elderly
    Katherine Tucker; Fiscal Year: 2007
    ..Three cores will work with all projects, including administrative, statistical, and laboratory cores. A pilot grants program during years 2 through 4 will encourage additional investigations relevant to the Center theme. ..
  3. Center for Research/Nutrition & Health among the Elderly
    Katherine Tucker; Fiscal Year: 2007
    ..Three cores will work with all projects, including administrative, statistical and laboratory cores. A pilot grants program during years 2-4 will encourage additional investigations relevant to the Center theme. ..