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Species | Katherine TuckerSummaryAffiliation: Tufts University Country: USA Publications
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Publications
Disparities in allele frequencies and population differentiation for 101 disease-associated single nucleotide polymorphisms between Puerto Ricans and non-Hispanic whitesJosiemer Mattei
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
BMC Genet 10:45. 2009....- Osteoporosis prevention and nutritionKatherine L Tucker
USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
Curr Osteoporos Rep 7:111-7. 2009..Current research on diet and bone status supports encouragement of balanced diets with plenty of fruit and vegetables, adequate dairy and other protein foods, and limitation of foods with low nutrient density... - Assessment of usual dietary intake in population studies of gene-diet interactionKatherine L Tucker
Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
Nutr Metab Cardiovasc Dis 17:74-81. 2007..Dietary intake is a critical environmental exposure when considering the effect of many genetic factors on disease risk. However, dietary intake is a complex and changing measure that requires particular care in assessment... - Colas, but not other carbonated beverages, are associated with low bone mineral density in older women: The Framingham Osteoporosis StudyKatherine L Tucker
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
Am J Clin Nutr 84:936-42. 2006..In addition to displacing healthier beverages, colas contain caffeine and phosphoric acid (H3PO4), which may adversely affect bone... - High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging StudyKatherine L Tucker
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
Am J Clin Nutr 82:627-35. 2005..It is not clear whether the observed associations between homocysteine and cognitive measures are causal or whether they are due to homocysteine, to independent actions of the B vitamins, or to both... - Dietary intake and bone status with agingKatherine L Tucker
Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington St, Boston, MA 02111, USA
Curr Pharm Des 9:2687-704. 2003..With advances in both genetics and nutrition, improved understanding of all these interactions will contribute to effective recommendations for prevention of bone loss and osteoporosis in the aging population... - Commentary: Dietary patterns in transition can inform health risk, but detailed assessments are needed to guide recommendationsKatherine Tucker
Dietary Assessment and Epidemiology Research Program, Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
Int J Epidemiol 36:610-1. 2007 - A regional food-frequency questionnaire for the US Mississippi DeltaKatherine L Tucker
Jean Mayer US Department of Agriculture USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
Public Health Nutr 8:87-96. 2005.... - Low plasma vitamin B12 is associated with lower BMD: the Framingham Osteoporosis StudyKatherine L Tucker
Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
J Bone Miner Res 20:152-8. 2005..Men with plasma B12 < 148 pM had significantly lower BMD at the hip, and women at the spine, relative to those with higher B12, and trends were similar for both at all sites. Low vitamin B12 may be a risk factor for low BMD... - Breakfast cereal fortified with folic acid, vitamin B-6, and vitamin B-12 increases vitamin concentrations and reduces homocysteine concentrations: a randomized trialKatherine L Tucker
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
Am J Clin Nutr 79:805-11. 2004..High homocysteine and low B vitamin concentrations have been linked to the risk of vascular disease, stroke, and dementia and are relatively common in older adults... - Effects of beer, wine, and liquor intakes on bone mineral density in older men and womenKatherine L Tucker
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
Am J Clin Nutr 89:1188-96. 2009..Moderate intake of alcohol has been reported to have beneficial effects on bone. However, different classes of alcoholic beverages have not been investigated... - Assessing dietary intake of drug-abusing Hispanic adults with and without human immunodeficiency virus infectionShivani Sahni
Jean Mayer US Department of Agriculture, Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111 1524, USA
J Am Diet Assoc 107:968-76. 2007..The selection of a dietary assessment method most appropriate for Hispanic adults with/without HIV infection who may be drug abusers remains unclear... - Associations of empirically derived eating patterns with plasma lipid biomarkers: a comparison of factor and cluster analysis methodsP K Newby
Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
Am J Clin Nutr 80:759-67. 2004..Despite the growing use of patterning methods in nutritional epidemiology, a direct comparison of factor and cluster analysis methods has not been performed... - Dietary factors associated with the risk of high iron stores in the elderly Framingham Heart Study cohortDiana J Fleming
Mineral Bioavailability Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
Am J Clin Nutr 76:1375-84. 2002..Individual dietary patterns may be important modulators of high iron stores... - Inverse association of carotenoid intakes with 4-y change in bone mineral density in elderly men and women: the Framingham Osteoporosis StudyShivani Sahni
Dietary Assessment and Epidemiology Research Program and the Antioxidants Research Laboratory, Jean Mayer US Department of Agriculture, HNRCA, Tufts University, Boston, MA 02111 1524, USA
Am J Clin Nutr 89:416-24. 2009..Few studies have examined the association between carotenoid intake (other than beta-carotene) and bone mineral density (BMD)... - APOA2, dietary fat, and body mass index: replication of a gene-diet interaction in 3 independent populationsDolores Corella
Nutrition and Genomics Laboratory, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, 711 Washington St, Boston, MA 02111 1524, USA
Arch Intern Med 169:1897-906. 2009..However, replication has been low. Our aim was to study interaction among a functional APOA2 polymorphism, food intake, and body mass index (BMI) in independent populations to replicate findings and to increase their evidence level... - Association between glucokinase regulatory protein (GCKR) and apolipoprotein A5 (APOA5) gene polymorphisms and triacylglycerol concentrations in fasting, postprandial, and fenofibrate-treated statesPablo Perez-Martinez
Nutrition and Genomics Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
Am J Clin Nutr 89:391-9. 2009..Hypertriglyceridemia is a risk factor for cardiovascular disease. Variation in the apolipoprotein A5 (APOA5) and glucokinase regulatory protein (GCKR) genes has been associated with fasting plasma triacylglycerol... - Intake of whole grains, refined grains, and cereal fiber measured with 7-d diet records and associations with risk factors for chronic diseaseP K Newby
Department of Pediatrics, Boston University School of Medicine, Boston Medical Center, Boston, MA 02118, USA
Am J Clin Nutr 86:1745-53. 2007..Single-nutrient studies are also needed to explore the mechanisms by which foods may be protective... - Serum carotenoid and tocopherol concentrations vary by dietary pattern among African AmericansSameera A Talegawkar
Tufts University, Boston, MA, USA
J Am Diet Assoc 108:2013-20. 2008..Intakes and biochemical concentrations of carotenoids and tocopherols have been associated with chronic diseases... - Higher dietary variety is associated with better nutritional status in frail elderly peopleMelissa A Bernstein
Gerald J and Dorothy R. Friedman School of Nutrition Science and Policy, Tufts University, USA
J Am Diet Assoc 102:1096-104. 2002..Preventive measures to improve dietary variety, as measured by the dietary variety score, should be evaluated and introduced before nutrition and health complications arise... - Apolipoprotein A5 and lipoprotein lipase interact to modulate anthropometric measures in Hispanics of Caribbean originCaren E Smith
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA
Obesity (Silver Spring) 18:327-32. 2010..Analyses of gene-gene interactions may improve understanding of genetically based obesity risk, and underscore the need for further study of groups with multiple ancestral admixtures... - alpha-Tocopherol intake and plasma concentration of Hispanic and non-Hispanic white elders is associated with dietary intake patternXiang Gao
The Jean Mayer U.S. Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
J Nutr 136:2574-9. 2006..05 for all), although they had similar intakes. A large proportion of these elders (>90%) have inadequate intake of alpha-tocopherol, and plasma concentrations were associated with intake patterns... - Longitudinal changes in food patterns predict changes in weight and body mass index and the effects are greatest in obese womenP K Newby
The Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
J Nutr 136:2580-7. 2006..Pattern analysis is helpful in generating hypotheses regarding the role of diet in obesity, and additional research is needed to understand which elements of our patterns are protective or risk factors for weight gain... - WDTC1, the ortholog of Drosophila adipose gene, associates with human obesity, modulated by MUFA intakeChao Qiang Lai
JM USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts, USA
Obesity (Silver Spring) 17:593-600. 2009..Given the high frequency of the major alleles in both populations, we suggest that WDTC1 variation may be an important risk factor contributing to obesity in these populations... - Apolipoprotein A5 polymorphisms interact with total dietary fat intake in association with markers of metabolic syndrome in Puerto Rican older adultsJosiemer Mattei
Jean Mayer USDA Human Nutrition Research Center on Aging, Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA
J Nutr 139:2301-8. 2009..Dietary fat intake seems to modulate these associations. The results contribute to the understanding of health disparities in this population... - Plasma C-reactive protein and homocysteine concentrations are related to frequent fruit and vegetable intake in Hispanic and non-Hispanic white eldersXiang Gao
The Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
J Nutr 134:913-8. 2004..Because both of these metabolites are known risk factors for CVD, these findings contribute to the evidence that a higher intake of fruit and vegetables may reduce the risk of CVD... - Polymorphisms in uracil-processing genes, but not one-carbon nutrients, are associated with altered DNA uracil concentrations in an urban Puerto Rican populationAurelie Chanson
Jean Mayer US Department of Agriculture, Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
Am J Clin Nutr 89:1927-36. 2009..Because of their metabolic function, folate and other one-carbon micronutrients may be important factors in the control of uracil misincorporation... - Vitamin B6 is associated with depressive symptomatology in Massachusetts eldersCRISTINA MERETE
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
J Am Coll Nutr 27:421-7. 2008.... - The maximal amount of dietary alpha-tocopherol intake in U.S. adults (NHANES 2001-2002)Xiang Gao
The Jean Mayer U.S. Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
J Nutr 136:1021-6. 2006..Careful selection of the highest vitamin E source foods within these groups could further increase the likelihood of meeting the current recommended daily allowance... - A traditional rice and beans pattern is associated with metabolic syndrome in Puerto Rican older adultsSabrina E Noel
USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
J Nutr 139:1360-7. 2009..8, 95% CI: 1.03, 3.3). Dietary patterns were significantly associated with metabolic syndrome and its components. More research is needed to make appropriate nutritional recommendations for this high-risk population... - Dietary and nondietary determinants of vitamin K biochemical measures in men and womenNicola M McKeown
Jean Mayer U.S. Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
J Nutr 132:1329-34. 2002..Despite these caveats, these findings support the use of a FFQ for a relative assessment of vitamin K status in population-based studies... - The 2005 USDA Food Guide Pyramid is associated with more adequate nutrient intakes within energy constraints than the 1992 PyramidXiang Gao
Harvard School of Public Health, Boston, MA, USA
J Nutr 136:1341-6. 2006..Our analysis suggests that following the 2005 FGP may be associated with lower energy and optimal nutrient intake. Careful restriction of discretionary calories appears necessary for appropriate energy intakes to be maintained... - Carotenoid intakes, assessed by food-frequency questionnaires (FFQs), are associated with serum carotenoid concentrations in the Jackson Heart Study: validation of the Jackson Heart Study Delta NIRI Adult FFQsSameera A Talegawkar
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
Public Health Nutr 11:989-97. 2008.... - Allostatic load is associated with chronic conditions in the Boston Puerto Rican Health StudyJosiemer Mattei
Tufts University, Boston, MA, USA
Soc Sci Med 70:1988-96. 2010..These results have prospective research implications for Puerto Ricans and other ethnic groups... - Polyunsaturated fatty acids interact with the PPARA-L162V polymorphism to affect plasma triglyceride and apolipoprotein C-III concentrations in the Framingham Heart StudyE Shyong Tai
Nutrition and Genomics Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111 1524, USA
J Nutr 135:397-403. 2005..Our data show that the effect of the L162V polymorphism on plasma TG and apoC-III concentrations depends on the dietary PUFA, with a high intake triggering lower TG in carriers of the 162V allele... - Intake of added sugar and sugar-sweetened drink and serum uric acid concentration in US men and womenXiang Gao
Department of Nutrition, Harvard University School of Public Health, Boston, MA 02115, USA
Hypertension 50:306-12. 2007..2; P for interaction <0.01). Further research is needed to confirm causality of these associations and the observed difference by gender... - A home-based nutrition intervention to increase consumption of fruits, vegetables, and calcium-rich foods in community dwelling eldersA Bernstein
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
J Am Diet Assoc 102:1421-7. 2002..Compliance should be encouraged with record keeping as well as through continuous monitoring and positive reinforcement... - Population admixture associated with disease prevalence in the Boston Puerto Rican health studyChao Qiang Lai
Nutrition and Genomics Laboratory, JM USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington St, Boston, MA 02111, USA
Hum Genet 125:199-209. 2009.... - APOA5 gene variation modulates the effects of dietary fat intake on body mass index and obesity risk in the Framingham Heart StudyDolores Corella
Nutrition and Genomics Laboratory, JM USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111 1524, USA
J Mol Med (Berl) 85:119-28. 2007..In conclusion, the APOA5-1131T>C SNP, which is present in approximately 13% of this population, modulates the effect of fat intake on BMI and obesity risk in both men and women... - Low vitamin B-12 intake and status are more prevalent in Hispanic older adults of Caribbean origin than in neighborhood-matched non-Hispanic whitesLaurinda L Kwan
The Jean Mayer U.S. Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
J Nutr 132:2059-64. 2002..As in other populations, sources of unbound vitamin B-12 such as supplements and fortified cereal appear to be protective. Dietary intervention programs targeted to the Hispanic population should promote these vitamin B-12 sources... - Validity of estimated dietary eicosapentaenoic acid and docosahexaenoic acid intakes determined by interviewer-administered food frequency questionnaire among older adults with mild-to-moderate cognitive impairment or dementiaLisa N Arsenault
Tufts University, Boston, Massachusetts 02124, USA
Am J Epidemiol 170:95-103. 2009..This frequency was consistently high across all cognitive categories. With interviewer administration, this FFQ seems to be a valid method of assessing dietary EPA + DHA intake in older adults with mild-to-moderate cognitive impairment... - Dietary pattern is associated with homocysteine and B vitamin status in an urban Chinese populationXiang Gao
The Jean Mayer U.S. Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
J Nutr 133:3636-42. 2003..Dietary patterns appear to play an important role in the micronutrient and homocysteine status of these Chinese adults... - High intra/interindividual variance ratios for energy and nutrient intakes of pregnant women in rural Malawi show that many days are required to estimate usual intakeJoshua Nyambose
School of Nutrition Science and Policy, the Jean Mayer U.S. Department of Agriculture Human Nutrition Research Center on Aging (HNRCA, Tufts University, Boston, MA 02111, USA
J Nutr 132:1313-8. 2002.... - MAT1A variants are associated with hypertension, stroke, and markers of DNA damage and are modulated by plasma vitamin B-6 and folateChao Qiang Lai
Nutrition and Genomics Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
Am J Clin Nutr 91:1377-86. 2010..The S-adenosylmethionine synthetase type 1 (MAT1A) gene encodes a key enzyme in one-carbon nutrient metabolism... - Air pollution and homocysteine: more evidence that oxidative stress-related genes modify effects of particulate air pollutionCizao Ren
Exposure, Epidemiology, and Risk Program, Harvard School of Public Health, Boston, MA 02215, USA
Epidemiology 21:198-206. 2010..nondeletion), and HMOX-1 (any short vs. both long). We attempted to replicate identified genes in an analysis of heart rate variability and in other outcomes reported in the literature... - Poor iron status is more prevalent in Hispanic than in non-Hispanic white older adults in MassachusettsErin L Seaverson
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
J Nutr 137:414-20. 2007..Cultural variation in dietary patterns may influence iron availability and body iron stores and contribute to an increased risk for iron deficiency anemia among some Hispanic older adults... - Meeting adequate intake for dietary calcium without dairy foods in adolescents aged 9 to 18 years (National Health and Nutrition Examination Survey 2001-2002)Xiang Gao
Department of Nutrition, Harvard University School of Public Health, Boston, MA 02111, USA
J Am Diet Assoc 106:1759-65. 2006..In addition, greater physical activity and responsible sunlight exposure should be encouraged to promote vitamin D adequacy... - Association of a common polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene with bone phenotypes depends on plasma folate statusRobert R McLean
Research and Training Institute, Hebrew Rehabilitation Center for Aged, Boston, Massachusetts 01702, USA
J Bone Miner Res 19:410-8. 2004..Our findings support the hypothesis that the association between an MTHFR polymorphism and bone phenotypes depends on folate status... - Association of vitamin B-6 status with inflammation, oxidative stress, and chronic inflammatory conditions: the Boston Puerto Rican Health StudyJian Shen
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111 1524, USA
Am J Clin Nutr 91:337-42. 2010..Low vitamin B-6 status has been linked to an increased risk of cardiovascular diseases. The cardioprotective effects of vitamin B-6 independent of homocysteine suggest that additional mechanisms may be involved... - High vitamin C intake is associated with lower 4-year bone loss in elderly menShivani Sahni
Dietary Assessment and Epidemiology Research Program, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
J Nutr 138:1931-8. 2008..Null associations were observed among women. These results suggest a possible protective role of vitamin C for bone health in older men... - Diet and risk of adult glioma in eastern Nebraska, United StatesHonglei Chen
Tufts University, Human Nutrition Research Center on Aging, Boston, MA, USA
Cancer Causes Control 13:647-55. 2002..CONCLUSION: Our study does not support the N-nitroso compound hypothesis, but suggests potential roles for carotenoids and possibly other phytochemicals in reducing risk of adult glioma... - Dietary patterns of Hispanic elders are associated with acculturation and obesityHai Lin
Jean Mayer U.S. Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
J Nutr 133:3651-7. 2003..Total and central obesity were positively associated with the rice pattern. Longitudinal studies are needed to clarify the causal nature of these associations... - Long-term stability of food patterns identified by use of factor analysis among Swedish womenP K Newby
Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
J Nutr 136:626-33. 2006..Testing whether patterns measured over a long time period can be used in analytic studies is the next step in assessing the validity of this method... - Relative influence of diet and physical activity on body composition in urban Chinese adultsManjiang Yao
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
Am J Clin Nutr 77:1409-16. 2003..These findings support previous studies in US adults and suggest that dietary variables other than fat have an important influence on adult body composition... - The combination of high fruit and vegetable and low saturated fat intakes is more protective against mortality in aging men than is either alone: the Baltimore Longitudinal Study of AgingKatherine L Tucker
Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
J Nutr 135:556-61. 2005..In addition, they extend these findings by demonstrating that the combination of both behaviors is more protective than either alone, suggesting that their beneficial effects are mediated by different mechanisms... - Hispanic and non-Hispanic white elders from Massachusetts have different patterns of carotenoid intake and plasma concentrationsOdilia I Bermudez
Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
J Nutr 135:1496-502. 2005..Because of the potential importance of carotenoids as protective factors against chronic diseases, more attention to food-related practices associated with carotenoid intake in differing population groups is warranted... - The effect of drug abuse on body mass index in Hispanics with and without HIV infectionJanet E Forrester
Department of Family Medicine and Community Health, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA
Public Health Nutr 8:61-8. 2005..The purpose of this study was to examine non-dietary factors that could affect the weight of drug abusers with and without HIV infection... - Stress and nutrition in relation to excess development of chronic disease in Puerto Rican adults living in the Northeastern USAKatherine L Tucker
Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111-1524, USA
J Med Invest 52:252-8. 2005..We further propose that the association between life stress, physiologic response and chronic conditions is modified by nutritional status, with a focus on B vitamins and antioxidant vitamins... - A randomized controlled trial of resistance exercise training to improve glycemic control in older adults with type 2 diabetesCarmen Castaneda
Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
Diabetes Care 25:2335-41. 2002..To determine the efficacy of high-intensity progressive resistance training (PRT) on glycemic control in older adults with type 2 diabetes... - Intake of lutein and zeaxanthin differ with age, sex, and ethnicityElizabeth J Johnson
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
J Am Diet Assoc 110:1357-62. 2010..Our findings suggest that the relative intake of lutein and zeaxanthin may be important to age-related macular degeneration risk. Future studies are needed to assess the individual associations of lutein and zeaxanthin in eye health... - Plasma B vitamins, homocysteine, and their relation with bone loss and hip fracture in elderly men and womenRobert R McLean
Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, Boston, MA 02131, USA
J Clin Endocrinol Metab 93:2206-12. 2008..Elevated homocysteine is a strong risk factor for osteoporotic fractures among elders, yet it may be a marker for low B-vitamin status... - Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: the Framingham Heart StudyErnst J Schaefer
Lipid Metabolism Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tuffs University, Boston, MA 02111, USA
Arch Neurol 63:1545-50. 2006..Docosahexaenoic acid (DHA) is an abundant fatty acid in the brain. In the diet, DHA is found mostly in fatty fish. The content of DHA has been shown to be decreased in the brain and plasma of patients with dementia... - Dietary patterns, approaches, and multicultural perspectiveKatherine L Tucker
Department of Health Sciences, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA
Appl Physiol Nutr Metab 35:211-8. 2010..Still, dietary pattern research has great potential for use in nutrition policy, particularly as it demonstrates the importance of total diet in health promotion... - Television viewing is associated with prevalence of metabolic syndrome in Hispanic eldersXiang Gao
Jean Mayer USDA HNRCA at Tufts University, 711 Washington St, Boston, MA 02111 1524, USA
Diabetes Care 30:694-700. 2007..We examined associations between television viewing and prevalence of the metabolic syndrome among a representative sample of Caribbean-origin Hispanic elders living in Massachusetts... - Homocysteine as a predictive factor for hip fracture in older personsRobert R McLean
Hebrew Rehabilitation Center for Aged Research and Training Institute, Boston, USA
N Engl J Med 350:2042-9. 2004..We examined the association between the total homocysteine concentration and the risk of hip fracture in men and women enrolled in the Framingham Study... - Residential traffic exposure, pulse pressure, and C-reactive protein: consistency and contrast among exposure characterization methodsChristine L Rioux
Department of Public Health and Community Medicine, Tufts University, Boston, Massachusetts 02155, USA
Environ Health Perspect 118:803-11. 2010..Traffic exposure may increase cardiovascular disease (CVD) risk via systemic inflammation and elevated blood pressure, two important clinical markers for managing disease progression... - Dietary and plasma lipid, lipoprotein, and apolipoprotein profiles among elderly Hispanics and non-Hispanics and their association with diabetesOdilia I Bermudez
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
Am J Clin Nutr 76:1214-21. 2002..There are limited data about dietary intakes and plasma lipids of elderly US Hispanics... - Dietary fat intake determines the effect of a common polymorphism in the hepatic lipase gene promoter on high-density lipoprotein metabolism: evidence of a strong dose effect in this gene-nutrient interaction in the Framingham StudyJose M Ordovas
Nutrition and Genomics Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, Mass 02111, USA
Circulation 106:2315-21. 2002..This allele has been associated with decreased HL activity and increased HDL-C concentrations. However, the effect is variable among populations... - Vitamin K intake and bone mineral density in women and menSarah L Booth
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
Am J Clin Nutr 77:512-6. 2003..Low dietary vitamin K intake has been associated with an increased risk of hip fracture in men and women. Few data exist on the association between dietary vitamin K intake and bone mineral density (BMD)... - Trends in dietary patterns of Latin American populationsOdilia I Bermudez
Jean Mayer U S Department of Agriculture, Human Nutrition Research Center on Aging, Tufts University, Boston, MA, 02111 1524, USA
Cad Saude Publica 19:S87-99. 2003..Efforts to educate the population on the importance of a healthy diet and to issue policies to improve the availability of a healthy food supply can help to reduce the rapid escalation of obesity and chronic diseases... - Dietary intake of n-6 fatty acids modulates effect of apolipoprotein A5 gene on plasma fasting triglycerides, remnant lipoprotein concentrations, and lipoprotein particle size: the Framingham Heart StudyChao Qiang Lai
Nutrition and Genomics Laboratory, JM USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
Circulation 113:2062-70. 2006..Apolipoprotein A5 gene (APOA5) variation is associated with plasma triglycerides (TGs). However, little is known about whether dietary fat modulates this association... - Bone mineral density and dietary patterns in older adults: the Framingham Osteoporosis StudyKatherine L Tucker
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
Am J Clin Nutr 76:245-52. 2002..Several nutrients are known to affect bone mineral density (BMD). However, these nutrients occur together in foods and dietary patterns, and the overall effects of dietary choices are not well understood... - Dietary intake and body mass index in HIV-positive and HIV-negative drug abusers of Hispanic ethnicityJanet E Forrester
Department of Familly Medicine and Community Health, Tufts University School of Medicine, Boston, MA 02111, USA
Public Health Nutr 7:863-70. 2004..Many studies have not considered possible concurrent HIV disease. The purpose of this study was to determine the relationship between drug abuse and dietary intake in Hispanic Americans with and without HIV infection... - Polyunsaturated fatty acids modulate the effects of the APOA1 G-A polymorphism on HDL-cholesterol concentrations in a sex-specific manner: the Framingham StudyJose M Ordovas
Nutrition and Genomics Laboratory, the Lipid Metabolism Laboratory and the Epidemiology Program, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston 02111, USA
Am J Clin Nutr 75:38-46. 2002..The A allele was shown to be associated with higher HDL-cholesterol concentrations in some studies but not in others... - Social support, life events, and psychological distress among the Puerto Rican population in the Boston area of the United StatesLuis M Falcon
Northeastern University, Boston, MA, USA
Aging Ment Health 13:863-73. 2009..The aim of this article is to investigate the role of social network support in ameliorating the psychological impact of life stressors that are prevalent for the older Puerto Rican population... - 25-Hydroxyvitamin D, dementia, and cerebrovascular pathology in elders receiving home servicesJ S Buell
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington St, Boston, MA 02111, USA
Neurology 74:18-26. 2010..However, no studies have examined the association between vitamin D status, dementia, and cranial MRI indicators of cerebrovascular disease (CVD)... - The maximal amount of alpha-tocopherol intake from foods alone in U.S. adults (1994-1996 CSFII): an analysis by linear programmingXiang Gao
The Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
Ann N Y Acad Sci 1031:385-6. 2004 - Nutritional, immunological and health status of the elderly population living in poor neighbourhoods of Quito, EcuadorFernando Sempertegui
Corporación Ecuatoriana de Biotecnología, Ave Colón 1468 y Nueve de Octubre Of 508, Quito, Ecuador
Br J Nutr 96:845-53. 2006..In conclusion, while few elderly Ecuadorians were underweight, obesity was common. Micronutrient deficiencies were prevalent and may contribute to reduced immunological responses in this population... - Calcium intake and prostate cancer risk in a long-term aging study: the Baltimore Longitudinal Study of AgingSonja I Berndt
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Urology 60:1118-23. 2002..73) for men with high dairy intakes compared with those with low dairy intakes. CONCLUSIONS: The results of this study suggest that calcium intake within moderate limits is not associated with a notably increased risk of prostate cancer... - Food patterns measured by factor analysis and anthropometric changes in adultsP K Newby
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, 9th Floor, Boston, MA 02111, USA
Am J Clin Nutr 80:504-13. 2004..Sixty-five percent of US adults are overweight, and 31% of these adults are obese. Obesity results from weight gains over time; however, dietary determinants of weight gain remain controversial... - Hypertension among Hispanic elders of a Caribbean origin in MassachusettsHai Lin
Jean Mayer US Department of Agriculture, Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
Ethn Dis 12:499-507. 2002..Investigation of genetic or other factors associated with this apparent excess risk of systolic hypertension among elderly Hispanics, particularly among women, is warranted... - A study of dietary patterns in the Mexican-American population and their association with obesityPatricia M Carrera
Department of Nutrition, University of Maryland, College Park, USA
J Am Diet Assoc 107:1735-42. 2007..We hypothesized that Mexican-American adults following a traditional diet would have a lower prevalence of obesity than those following a more typical American diet... - Association of energy intake with prostate cancer in a long-term aging study: Baltimore Longitudinal Study of Aging (United States)Lillian J Hsieh
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Urology 61:297-301. 2003..CONCLUSIONS: This analysis, in which we used current energy intake as a surrogate for past prediagnostic intake, suggests a higher risk of prostate cancer with increased energy intake... - Homocysteine and B vitamins relate to brain volume and white-matter changes in geriatric patients with psychiatric disordersTammy Maria Scott
Department of Psychiatry, Tufts New England Medical Center, and Tufts University School of Medicine, Boston, MA 02446, USA
Am J Geriatr Psychiatry 12:631-8. 2004..The authors examined the relationship of homocysteine, folate, and vitamin B12 with magnetic resonance imaging (MRI) markers of neuropathology... - Traffic-related particles are associated with elevated homocysteine: the VA normative aging studySung Kyun Park
Department of Environmental Health Sciences, University of Michigan School of Public Health, 109 S Observatory Street, SPH II M6240, Ann Arbor, MI 48109, USA
Am J Respir Crit Care Med 178:283-9. 2008..Particulate air pollution has been related to cardiovascular death and hospital admission, but the underlying mechanisms are not fully elucidated... - Dietary silicon intake is positively associated with bone mineral density in men and premenopausal women of the Framingham Offspring cohortRavin Jugdaohsingh
Gastrointestinal Laboratory, The Rayne Institute, St Thomas Hospital, London, United Kingdom
J Bone Miner Res 19:297-307. 2004.... - Dietary behaviors, physical activity, and cigarette smoking among pregnant Puerto Rican womenAudra Gollenberg
Division of Biostatistics and Epidemiology, Department of Public Health, the School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA, USA
Am J Clin Nutr 87:1844-51. 2008..Few studies have examined predictors of meeting health guidelines in pregnancy among Latina women... - PPARG by dietary fat interaction influences bone mass in mice and humansCheryl L Ackert-Bicknell
The Jackson Laboratory, Bar Harbor, Maine 04609, USA
J Bone Miner Res 23:1398-408. 2008..These findings suggest that dietary fat has a significant influence on BMD that is dependent on the alleles present for the PPARG gene... - Risk of overweight and obesity among semivegetarian, lactovegetarian, and vegan womenP K Newby
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
Am J Clin Nutr 81:1267-74. 2005..Observational studies suggest that a plant-based diet is inversely related to body mass index (BMI), overweight, and obesity...
Research Grants
- Nutrition, Stress and Bone in Older Puerto RicansKatherine Tucker; Fiscal Year: 2007....
- Center for Research/Nutrition & Health among the ElderlyKatherine Tucker; Fiscal Year: 2007..Three cores will work with all projects, including administrative, statistical, and laboratory cores. A pilot grants program during years 2 through 4 will encourage additional investigations relevant to the Center theme. ..
- Center for Research/Nutrition & Health among the ElderlyKatherine Tucker; Fiscal Year: 2007..Three cores will work with all projects, including administrative, statistical and laboratory cores. A pilot grants program during years 2-4 will encourage additional investigations relevant to the Center theme. ..