K L Tucker

Summary

Affiliation: Tufts University
Country: USA

Publications

  1. ncbi request reprint alpha-Tocopherol intake and plasma concentration of Hispanic and non-Hispanic white elders is associated with dietary intake pattern
    Xiang Gao
    The Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Nutr 136:2574-9. 2006
  2. pmc PPARG by dietary fat interaction influences bone mass in mice and humans
    Cheryl L Ackert-Bicknell
    The Jackson Laboratory, Bar Harbor, Maine 04609, USA
    J Bone Miner Res 23:1398-408. 2008
  3. ncbi request reprint Nutrition and aging in developing countries
    K L Tucker
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Nutr 131:2417S-23S. 2001
  4. pmc Type 2 diabetes is prevalent and poorly controlled among Hispanic elders of Caribbean origin
    K L Tucker
    USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Public Health 90:1288-93. 2000
  5. ncbi request reprint The acid-base hypothesis: diet and bone in the Framingham Osteoporosis Study
    K L Tucker
    Jean Mayer USDA Human Nutrition Research, Center on Aging at Tufts University, Boston, MA 02111, USA
    Eur J Nutr 40:231-7. 2001
  6. ncbi request reprint Bone mineral density and dietary patterns in older adults: the Framingham Osteoporosis Study
    Katherine L Tucker
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 76:245-52. 2002
  7. ncbi request reprint Self-reported prevalence and health correlates of functional limitation among Massachusetts elderly Puerto Ricans, Dominicans, and non-Hispanic white neighborhood comparison group
    K L Tucker
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Gerontol A Biol Sci Med Sci 55:M90-7. 2000
  8. ncbi request reprint Plasma vitamin B-12 concentrations relate to intake source in the Framingham Offspring study
    K L Tucker
    Jean Mayer Human Nutrition Research Center on Aging at Tufts University, Boston MA 02111, USA
    Am J Clin Nutr 71:514-22. 2000
  9. ncbi request reprint Potassium, magnesium, and fruit and vegetable intakes are associated with greater bone mineral density in elderly men and women
    K L Tucker
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 69:727-36. 1999
  10. pmc 25-Hydroxyvitamin D, dementia, and cerebrovascular pathology in elders receiving home services
    J S Buell
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington St, Boston, MA 02111, USA
    Neurology 74:18-26. 2010

Collaborators

Detail Information

Publications113 found, 100 shown here

  1. ncbi request reprint alpha-Tocopherol intake and plasma concentration of Hispanic and non-Hispanic white elders is associated with dietary intake pattern
    Xiang Gao
    The Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Nutr 136:2574-9. 2006
    ..05 for all), although they had similar intakes. A large proportion of these elders (>90%) have inadequate intake of alpha-tocopherol, and plasma concentrations were associated with intake patterns...
  2. pmc PPARG by dietary fat interaction influences bone mass in mice and humans
    Cheryl L Ackert-Bicknell
    The Jackson Laboratory, Bar Harbor, Maine 04609, USA
    J Bone Miner Res 23:1398-408. 2008
    ..These findings suggest that dietary fat has a significant influence on BMD that is dependent on the alleles present for the PPARG gene...
  3. ncbi request reprint Nutrition and aging in developing countries
    K L Tucker
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Nutr 131:2417S-23S. 2001
    ..To reduce the impending burden of disease and disability worldwide, urgent action is needed to understand and to address the nutritional needs of the aging population...
  4. pmc Type 2 diabetes is prevalent and poorly controlled among Hispanic elders of Caribbean origin
    K L Tucker
    USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Public Health 90:1288-93. 2000
    ....
  5. ncbi request reprint The acid-base hypothesis: diet and bone in the Framingham Osteoporosis Study
    K L Tucker
    Jean Mayer USDA Human Nutrition Research, Center on Aging at Tufts University, Boston, MA 02111, USA
    Eur J Nutr 40:231-7. 2001
    ..There continues to be considerable debate about the role of acid vs. basic components of the diet on the long-term status of bone mineral density...
  6. ncbi request reprint Bone mineral density and dietary patterns in older adults: the Framingham Osteoporosis Study
    Katherine L Tucker
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 76:245-52. 2002
    ..Several nutrients are known to affect bone mineral density (BMD). However, these nutrients occur together in foods and dietary patterns, and the overall effects of dietary choices are not well understood...
  7. ncbi request reprint Self-reported prevalence and health correlates of functional limitation among Massachusetts elderly Puerto Ricans, Dominicans, and non-Hispanic white neighborhood comparison group
    K L Tucker
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Gerontol A Biol Sci Med Sci 55:M90-7. 2000
    ..Limited data suggest that Puerto Ricans experience greater disability than other ethnic groups, but few studies have examined the factors associated with this apparent difference...
  8. ncbi request reprint Plasma vitamin B-12 concentrations relate to intake source in the Framingham Offspring study
    K L Tucker
    Jean Mayer Human Nutrition Research Center on Aging at Tufts University, Boston MA 02111, USA
    Am J Clin Nutr 71:514-22. 2000
    ..Low vitamin B-12 status is prevalent among the elderly, but few studies have examined the association between vitamin B-12 status and intake...
  9. ncbi request reprint Potassium, magnesium, and fruit and vegetable intakes are associated with greater bone mineral density in elderly men and women
    K L Tucker
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 69:727-36. 1999
    ..Osteoporosis and related fractures will be growing public health problems as the population ages. It is therefore of great importance to identify modifiable risk factors...
  10. pmc 25-Hydroxyvitamin D, dementia, and cerebrovascular pathology in elders receiving home services
    J S Buell
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington St, Boston, MA 02111, USA
    Neurology 74:18-26. 2010
    ..However, no studies have examined the association between vitamin D status, dementia, and cranial MRI indicators of cerebrovascular disease (CVD)...
  11. ncbi request reprint Protein nutritional status and function are associated with type 2 diabetes in Hispanic elders
    C Castaneda
    US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston
    Am J Clin Nutr 72:89-95. 2000
    ..Hispanic elders have a high prevalence of diabetes and poor glycemic control, leading to inadequate nutritional status, muscle wasting, and impaired function...
  12. ncbi request reprint Assessing dietary intake of drug-abusing Hispanic adults with and without human immunodeficiency virus infection
    Shivani Sahni
    Jean Mayer US Department of Agriculture, Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111 1524, USA
    J Am Diet Assoc 107:968-76. 2007
    ..The selection of a dietary assessment method most appropriate for Hispanic adults with/without HIV infection who may be drug abusers remains unclear...
  13. ncbi request reprint Dietary vitamin K intakes are associated with hip fracture but not with bone mineral density in elderly men and women
    S L Booth
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, USA
    Am J Clin Nutr 71:1201-8. 2000
    ..Vitamin K has been associated with bone mineral density (BMD) and risk of hip fracture. The apolipoprotein (apo) E4 allele (APOE*E4) has been associated with bone fracture through a putative effect on vitamin K transport in blood...
  14. ncbi request reprint Associations of empirically derived eating patterns with plasma lipid biomarkers: a comparison of factor and cluster analysis methods
    P K Newby
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Am J Clin Nutr 80:759-67. 2004
    ..Despite the growing use of patterning methods in nutritional epidemiology, a direct comparison of factor and cluster analysis methods has not been performed...
  15. ncbi request reprint Dietary factors associated with the risk of high iron stores in the elderly Framingham Heart Study cohort
    Diana J Fleming
    Mineral Bioavailability Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 76:1375-84. 2002
    ..High body iron stores may increase the risk of several chronic diseases. Whether dietary factors contribute to the risk of high iron stores is unknown...
  16. pmc Inverse association of carotenoid intakes with 4-y change in bone mineral density in elderly men and women: the Framingham Osteoporosis Study
    Shivani Sahni
    Dietary Assessment and Epidemiology Research Program and the Antioxidants Research Laboratory, Jean Mayer US Department of Agriculture, HNRCA, Tufts University, Boston, MA 02111 1524, USA
    Am J Clin Nutr 89:416-24. 2009
    ..Few studies have examined the association between carotenoid intake (other than beta-carotene) and bone mineral density (BMD)...
  17. ncbi request reprint Total and central obesity among elderly Hispanics and the association with Type 2 diabetes
    O I Bermudez
    Dietary Assessment Research Program, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Obes Res 9:443-51. 2001
    ....
  18. doi request reprint A composite scoring of genotypes discriminates coronary heart disease risk beyond conventional risk factors in the Boston Puerto Rican Health Study
    M Junyent
    The Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University School of Medicine, Boston, MA 02111, USA
    Nutr Metab Cardiovasc Dis 20:157-64. 2010
    ....
  19. ncbi request reprint Plasma 25-hydroxyvitamin D and its determinants in an elderly population sample
    P F Jacques
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 66:929-36. 1997
    ..Results from this population-based sample of elderly individuals suggest that inadequate vitamin D status is an important public health problem, which could be readily addressed by adequate vitamin D intake or sunlight exposure...
  20. pmc Association between glucokinase regulatory protein (GCKR) and apolipoprotein A5 (APOA5) gene polymorphisms and triacylglycerol concentrations in fasting, postprandial, and fenofibrate-treated states
    Pablo Perez-Martinez
    Nutrition and Genomics Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    Am J Clin Nutr 89:391-9. 2009
    ..Hypertriglyceridemia is a risk factor for cardiovascular disease. Variation in the apolipoprotein A5 (APOA5) and glucokinase regulatory protein (GCKR) genes has been associated with fasting plasma triacylglycerol...
  21. pmc Intake of whole grains, refined grains, and cereal fiber measured with 7-d diet records and associations with risk factors for chronic disease
    P K Newby
    Department of Pediatrics, Boston University School of Medicine, Boston Medical Center, Boston, MA 02118, USA
    Am J Clin Nutr 86:1745-53. 2007
    ..Single-nutrient studies are also needed to explore the mechanisms by which foods may be protective...
  22. pmc Serum carotenoid and tocopherol concentrations vary by dietary pattern among African Americans
    Sameera A Talegawkar
    Tufts University, Boston, MA, USA
    J Am Diet Assoc 108:2013-20. 2008
    ..Intakes and biochemical concentrations of carotenoids and tocopherols have been associated with chronic diseases...
  23. ncbi request reprint Higher dietary variety is associated with better nutritional status in frail elderly people
    Melissa A Bernstein
    Gerald J and Dorothy R Friedman School of Nutrition Science and Policy, Tufts University, USA
    J Am Diet Assoc 102:1096-104. 2002
    ..A narrow range of food choices may lead to dietary inadequacies, a particular concern in elderly people. We hypothesized that consumption of a more diverse diet would predict better nutritional status in frail elderly persons...
  24. ncbi request reprint The energy expenditure of postmenopausal women classified as restrained or unrestrained eaters
    G P Bathalon
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
    Eur J Clin Nutr 55:1059-67. 2001
    ..SPONSORSHIP: NIH grants AG12829, DK46124 and T32AG00209, and US Cooperative Agreement number 58-1950-9-001...
  25. pmc Protective effect of total and supplemental vitamin C intake on the risk of hip fracture--a 17-year follow-up from the Framingham Osteoporosis Study
    S Sahni
    Dietary Assessment and Epidemiology Research Program, Jean Mayer USDA Human Nutrition Research Center on Aging HNRCA and Friedman School of Nutrition Science and Policy FSNSP, Tufts University, Boston, MA, USA
    Osteoporos Int 20:1853-61. 2009
    ..Therefore, vitamin C may have a protective effect on bone health in older adults...
  26. ncbi request reprint Longitudinal changes in food patterns predict changes in weight and body mass index and the effects are greatest in obese women
    P K Newby
    The Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Nutr 136:2580-7. 2006
    ..Pattern analysis is helpful in generating hypotheses regarding the role of diet in obesity, and additional research is needed to understand which elements of our patterns are protective or risk factors for weight gain...
  27. pmc Apolipoprotein A5 and lipoprotein lipase interact to modulate anthropometric measures in Hispanics of Caribbean origin
    Caren E Smith
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA
    Obesity (Silver Spring) 18:327-32. 2010
    ..Analyses of gene-gene interactions may improve understanding of genetically based obesity risk, and underscore the need for further study of groups with multiple ancestral admixtures...
  28. pmc Apolipoprotein A5 polymorphisms interact with total dietary fat intake in association with markers of metabolic syndrome in Puerto Rican older adults
    Josiemer Mattei
    Jean Mayer USDA Human Nutrition Research Center on Aging, Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA
    J Nutr 139:2301-8. 2009
    ..Dietary fat intake seems to modulate these associations. The results contribute to the understanding of health disparities in this population...
  29. pmc WDTC1, the ortholog of Drosophila adipose gene, associates with human obesity, modulated by MUFA intake
    Chao Qiang Lai
    JM USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts, USA
    Obesity (Silver Spring) 17:593-600. 2009
    ..Given the high frequency of the major alleles in both populations, we suggest that WDTC1 variation may be an important risk factor contributing to obesity in these populations...
  30. ncbi request reprint Iron status of the free-living, elderly Framingham Heart Study cohort: an iron-replete population with a high prevalence of elevated iron stores
    D J Fleming
    Mineral Bioavailability Laboratory and the Epidemiology Program, Jean Mayer-US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    Am J Clin Nutr 73:638-46. 2001
    ..The likely liability in iron nutriture in free-living, elderly white Americans eating a Western diet is high iron stores, not iron deficiency...
  31. doi request reprint The effects of ABCG5/G8 polymorphisms on HDL-cholesterol concentrations depend on ABCA1 genetic variants in the Boston Puerto Rican Health Study
    M Junyent
    The Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University School of Medicine, Boston, MA 02111, USA
    Nutr Metab Cardiovasc Dis 20:558-66. 2010
    ....
  32. ncbi request reprint Development of sex-specific equations for estimating stature of frail elderly Hispanics living in the northeastern United States
    O I Bermudez
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    Am J Clin Nutr 69:992-8. 1999
    ..The accurate measurement of stature is not possible in many frail elderly persons because of problems affecting their ability to stand straight. In such cases, knee height may be used to estimate stature...
  33. pmc Does dietary protein reduce hip fracture risk in elders? The Framingham Osteoporosis Study
    D Misra
    Department of Rheumatology, Boston University Medical Center, Boston, MA, USA
    Osteoporos Int 22:345-9. 2011
    ..We examined association between energy-adjusted protein intake and hip fracture risk in elders. The risk of hip fracture was reduced in upper quartiles of protein intake when compared with lowest quartile...
  34. ncbi request reprint Dietary and nondietary determinants of vitamin K biochemical measures in men and women
    Nicola M McKeown
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Nutr 132:1329-34. 2002
    ..Despite these caveats, these findings support the use of a FFQ for a relative assessment of vitamin K status in population-based studies...
  35. ncbi request reprint Plasma C-reactive protein and homocysteine concentrations are related to frequent fruit and vegetable intake in Hispanic and non-Hispanic white elders
    Xiang Gao
    The Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Nutr 134:913-8. 2004
    ..Because both of these metabolites are known risk factors for CVD, these findings contribute to the evidence that a higher intake of fruit and vegetables may reduce the risk of CVD...
  36. pmc Vitamin B6 is associated with depressive symptomatology in Massachusetts elders
    CRISTINA MERETE
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Am Coll Nutr 27:421-7. 2008
    ....
  37. pmc Polymorphisms in uracil-processing genes, but not one-carbon nutrients, are associated with altered DNA uracil concentrations in an urban Puerto Rican population
    Aurelie Chanson
    Jean Mayer US Department of Agriculture, Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 89:1927-36. 2009
    ..Because of their metabolic function, folate and other one-carbon micronutrients may be important factors in the control of uracil misincorporation...
  38. pmc Carotenoid intakes, assessed by food-frequency questionnaires (FFQs), are associated with serum carotenoid concentrations in the Jackson Heart Study: validation of the Jackson Heart Study Delta NIRI Adult FFQs
    Sameera A Talegawkar
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Public Health Nutr 11:989-97. 2008
    ....
  39. pmc A traditional rice and beans pattern is associated with metabolic syndrome in Puerto Rican older adults
    Sabrina E Noel
    USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Nutr 139:1360-7. 2009
    ..8, 95% CI: 1.03, 3.3). Dietary patterns were significantly associated with metabolic syndrome and its components. More research is needed to make appropriate nutritional recommendations for this high-risk population...
  40. ncbi request reprint The maximal amount of dietary alpha-tocopherol intake in U.S. adults (NHANES 2001-2002)
    Xiang Gao
    The Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
    J Nutr 136:1021-6. 2006
    ..Careful selection of the highest vitamin E source foods within these groups could further increase the likelihood of meeting the current recommended daily allowance...
  41. ncbi request reprint The 2005 USDA Food Guide Pyramid is associated with more adequate nutrient intakes within energy constraints than the 1992 Pyramid
    Xiang Gao
    Harvard School of Public Health, Boston, MA, USA
    J Nutr 136:1341-6. 2006
    ..Our analysis suggests that following the 2005 FGP may be associated with lower energy and optimal nutrient intake. Careful restriction of discretionary calories appears necessary for appropriate energy intakes to be maintained...
  42. pmc The APOA1/C3/A4/A5 cluster and markers of allostatic load in the Boston Puerto Rican Health Study
    J Mattei
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Nutr Metab Cardiovasc Dis 21:862-70. 2011
    ..We aimed to determine the association between polymorphisms in the APOA1/C3/A4/A5 cluster with allostatic load parameters, alone, and in interaction with dietary fat intake in Puerto Ricans adults...
  43. ncbi request reprint Polyunsaturated fatty acids interact with the PPARA-L162V polymorphism to affect plasma triglyceride and apolipoprotein C-III concentrations in the Framingham Heart Study
    E Shyong Tai
    Nutrition and Genomics Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111 1524, USA
    J Nutr 135:397-403. 2005
    ..Our data show that the effect of the L162V polymorphism on plasma TG and apoC-III concentrations depends on the dietary PUFA, with a high intake triggering lower TG in carriers of the 162V allele...
  44. ncbi request reprint A home-based nutrition intervention to increase consumption of fruits, vegetables, and calcium-rich foods in community dwelling elders
    A Bernstein
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Am Diet Assoc 102:1421-7. 2002
    ..To increase fruit, vegetable, and calcium-rich food consumption in community-dwelling, functionally impaired elderly...
  45. ncbi request reprint High intra/interindividual variance ratios for energy and nutrient intakes of pregnant women in rural Malawi show that many days are required to estimate usual intake
    Joshua Nyambose
    School of Nutrition Science and Policy, the Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging HNRCA, Tufts University, Boston, MA 02111, USA
    J Nutr 132:1313-8. 2002
    ....
  46. ncbi request reprint Intake of added sugar and sugar-sweetened drink and serum uric acid concentration in US men and women
    Xiang Gao
    Department of Nutrition, Harvard University School of Public Health, Boston, MA 02115, USA
    Hypertension 50:306-12. 2007
    ..2; P for interaction <0.01). Further research is needed to confirm causality of these associations and the observed difference by gender...
  47. pmc Population admixture associated with disease prevalence in the Boston Puerto Rican health study
    Chao Qiang Lai
    Nutrition and Genomics Laboratory, JM USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington St, Boston, MA 02111, USA
    Hum Genet 125:199-209. 2009
    ....
  48. ncbi request reprint Low vitamin B-12 intake and status are more prevalent in Hispanic older adults of Caribbean origin than in neighborhood-matched non-Hispanic whites
    Laurinda L Kwan
    The Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Nutr 132:2059-64. 2002
    ..As in other populations, sources of unbound vitamin B-12 such as supplements and fortified cereal appear to be protective. Dietary intervention programs targeted to the Hispanic population should promote these vitamin B-12 sources...
  49. ncbi request reprint APOA5 gene variation modulates the effects of dietary fat intake on body mass index and obesity risk in the Framingham Heart Study
    Dolores Corella
    Nutrition and Genomics Laboratory, JM USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111 1524, USA
    J Mol Med (Berl) 85:119-28. 2007
    ..In conclusion, the APOA5-1131T>C SNP, which is present in approximately 13% of this population, modulates the effect of fat intake on BMI and obesity risk in both men and women...
  50. doi request reprint Air pollution and homocysteine: more evidence that oxidative stress-related genes modify effects of particulate air pollution
    Cizao Ren
    Exposure, Epidemiology, and Risk Program, Harvard School of Public Health, Boston, MA 02215, USA
    Epidemiology 21:198-206. 2010
    ..nondeletion), and HMOX-1 (any short vs. both long). We attempted to replicate identified genes in an analysis of heart rate variability and in other outcomes reported in the literature...
  51. pmc MAT1A variants are associated with hypertension, stroke, and markers of DNA damage and are modulated by plasma vitamin B-6 and folate
    Chao Qiang Lai
    Nutrition and Genomics Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 91:1377-86. 2010
    ..The S-adenosylmethionine synthetase type 1 (MAT1A) gene encodes a key enzyme in one-carbon nutrient metabolism...
  52. ncbi request reprint Dietary pattern is associated with homocysteine and B vitamin status in an urban Chinese population
    Xiang Gao
    The Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Nutr 133:3636-42. 2003
    ..Dietary patterns appear to play an important role in the micronutrient and homocysteine status of these Chinese adults...
  53. pmc Validity of estimated dietary eicosapentaenoic acid and docosahexaenoic acid intakes determined by interviewer-administered food frequency questionnaire among older adults with mild-to-moderate cognitive impairment or dementia
    Lisa N Arsenault
    Tufts University, Boston, Massachusetts 02124, USA
    Am J Epidemiol 170:95-103. 2009
    ..This frequency was consistently high across all cognitive categories. With interviewer administration, this FFQ seems to be a valid method of assessing dietary EPA + DHA intake in older adults with mild-to-moderate cognitive impairment...
  54. ncbi request reprint Frequency of ApoB and ApoE gene mutations as causes of hypobetalipoproteinemia in the framingham offspring population
    F K Welty
    Lipid Metabolism Laboratory, Jean Mayer Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
    Arterioscler Thromb Vasc Biol 18:1745-51. 1998
    ..21). In conclusion, a truncated apoB was a rare cause of HBLP, whereas the E2/E3 genotype was a much more common cause. A large prospective study is needed to evaluate the incidence of cancer and atherosclerosis in subjects with HBLP...
  55. ncbi request reprint Multivitamin use and B vitamin status in a homebound elderly population
    J S Buell
    K L Tucker, USDA HNRCA at Tufts University, 711 Washington Street 9th Floor, Boston, MA 02111, USA
    J Nutr Health Aging 11:299-303. 2007
    ..The purpose of this analysis is to investigate, in a racially diverse group of homebound elders, the association of multivitamin use with measures of plasma B vitamin concentrations...
  56. ncbi request reprint Prevalence and correlates of depressive symptoms among Hispanic elders in Massachusetts
    L M Falcon
    Department of Sociology, Northeastern University, Boston, Massachusetts 02115, USA
    J Gerontol B Psychol Sci Soc Sci 55:S108-16. 2000
    ....
  57. ncbi request reprint Relationships between use of television during meals and children's food consumption patterns
    K A Coon
    School of Nutrition, Science and Policy, Tufts University, Boston, Massachusetts, USA
    Pediatrics 107:E7. 2001
    ....
  58. ncbi request reprint Association of a common polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene with bone phenotypes depends on plasma folate status
    Robert R McLean
    Research and Training Institute, Hebrew Rehabilitation Center for Aged, Boston, Massachusetts 01702, USA
    J Bone Miner Res 19:410-8. 2004
    ..Our findings support the hypothesis that the association between an MTHFR polymorphism and bone phenotypes depends on folate status...
  59. ncbi request reprint Meeting adequate intake for dietary calcium without dairy foods in adolescents aged 9 to 18 years (National Health and Nutrition Examination Survey 2001-2002)
    Xiang Gao
    Department of Nutrition, Harvard University School of Public Health, Boston, MA 02111, USA
    J Am Diet Assoc 106:1759-65. 2006
    ..However, no studies have addressed whether dairy-free diets can provide adequate calcium while meeting other nutrient recommendations...
  60. ncbi request reprint Dietary patterns of Hispanic elders are associated with acculturation and obesity
    Hai Lin
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Nutr 133:3651-7. 2003
    ..Total and central obesity were positively associated with the rice pattern. Longitudinal studies are needed to clarify the causal nature of these associations...
  61. pmc High vitamin C intake is associated with lower 4-year bone loss in elderly men
    Shivani Sahni
    Dietary Assessment and Epidemiology Research Program, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Nutr 138:1931-8. 2008
    ..Null associations were observed among women. These results suggest a possible protective role of vitamin C for bone health in older men...
  62. ncbi request reprint Long-term stability of food patterns identified by use of factor analysis among Swedish women
    P K Newby
    Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Nutr 136:626-33. 2006
    ..Testing whether patterns measured over a long time period can be used in analytic studies is the next step in assessing the validity of this method...
  63. pmc Poor iron status is more prevalent in Hispanic than in non-Hispanic white older adults in Massachusetts
    Erin L Seaverson
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Nutr 137:414-20. 2007
    ..Cultural variation in dietary patterns may influence iron availability and body iron stores and contribute to an increased risk for iron deficiency anemia among some Hispanic older adults...
  64. ncbi request reprint Diet and risk of adult glioma in eastern Nebraska, United States
    Honglei Chen
    Tufts University, Human Nutrition Research Center on Aging, Boston, MA, USA
    Cancer Causes Control 13:647-55. 2002
    ..To investigate potential associations between diet and adult glioma...
  65. ncbi request reprint Relative influence of diet and physical activity on body composition in urban Chinese adults
    Manjiang Yao
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 77:1409-16. 2003
    ..The relative influence of diet and physical activity on body fatness remains uncertain...
  66. pmc Association of vitamin B-6 status with inflammation, oxidative stress, and chronic inflammatory conditions: the Boston Puerto Rican Health Study
    Jian Shen
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111 1524, USA
    Am J Clin Nutr 91:337-42. 2010
    ..Low vitamin B-6 status has been linked to an increased risk of cardiovascular diseases. The cardioprotective effects of vitamin B-6 independent of homocysteine suggest that additional mechanisms may be involved...
  67. doi request reprint The value of physiologic vitamin D as a biomarker of dementia
    J S Buell
    Harvard Clinical Research Institute, Boston, Massachusetts, USA
    Drugs Today (Barc) 47:223-31. 2011
    ....
  68. pmc Dietary intake of vitamin B-6, plasma pyridoxal 5'-phosphate, and homocysteine in Puerto Rican adults
    Xingwang Ye
    Department of Health Sciences, Northeastern University, Boston, MA 02115, USA
    J Am Diet Assoc 110:1660-8. 2010
    ..Vitamin B-6 is an important cofactor in many metabolic processes. However, vitamin B-6 intake and plasma status have not been well studied in the Puerto Rican population, a group with documented health disparities...
  69. ncbi request reprint The effect of drug abuse on body mass index in Hispanics with and without HIV infection
    Janet E Forrester
    Department of Family Medicine and Community Health, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA
    Public Health Nutr 8:61-8. 2005
    ..The purpose of this study was to examine non-dietary factors that could affect the weight of drug abusers with and without HIV infection...
  70. pmc Perilipin polymorphism interacts with dietary carbohydrates to modulate anthropometric traits in hispanics of Caribbean origin
    Caren E Smith
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University School of Medicine, Boston, MA 02111, USA
    J Nutr 138:1852-8. 2008
    ..These interactions may be relevant to dietary management of obesity...
  71. ncbi request reprint Homocysteine as a predictive factor for hip fracture in older persons
    Robert R McLean
    Hebrew Rehabilitation Center for Aged Research and Training Institute, Boston, USA
    N Engl J Med 350:2042-9. 2004
    ..We examined the association between the total homocysteine concentration and the risk of hip fracture in men and women enrolled in the Framingham Study...
  72. pmc Effects of beer, wine, and liquor intakes on bone mineral density in older men and women
    Katherine L Tucker
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 89:1188-96. 2009
    ..Moderate intake of alcohol has been reported to have beneficial effects on bone. However, different classes of alcoholic beverages have not been investigated...
  73. ncbi request reprint Breakfast cereal fortified with folic acid, vitamin B-6, and vitamin B-12 increases vitamin concentrations and reduces homocysteine concentrations: a randomized trial
    Katherine L Tucker
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Am J Clin Nutr 79:805-11. 2004
    ..High homocysteine and low B vitamin concentrations have been linked to the risk of vascular disease, stroke, and dementia and are relatively common in older adults...
  74. ncbi request reprint Vitamin K intake and bone mineral density in women and men
    Sarah L Booth
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 77:512-6. 2003
    ..Low dietary vitamin K intake has been associated with an increased risk of hip fracture in men and women. Few data exist on the association between dietary vitamin K intake and bone mineral density (BMD)...
  75. ncbi request reprint Hypertension among Hispanic elders of a Caribbean origin in Massachusetts
    Hai Lin
    Jean Mayer US Department of Agriculture, Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    Ethn Dis 12:499-507. 2002
    ..We determined the prevalence and associated risk factors of hypertension in Hispanic elders, ages 60-92 years, living in Massachusetts...
  76. ncbi request reprint A randomized controlled trial of resistance exercise training to improve glycemic control in older adults with type 2 diabetes
    Carmen Castaneda
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    Diabetes Care 25:2335-41. 2002
    ..To determine the efficacy of high-intensity progressive resistance training (PRT) on glycemic control in older adults with type 2 diabetes...
  77. ncbi request reprint Osteoporosis prevention and nutrition
    Katherine L Tucker
    USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Curr Osteoporos Rep 7:111-7. 2009
    ..Current research on diet and bone status supports encouragement of balanced diets with plenty of fruit and vegetables, adequate dairy and other protein foods, and limitation of foods with low nutrient density...
  78. pmc Residential traffic exposure, pulse pressure, and C-reactive protein: consistency and contrast among exposure characterization methods
    Christine L Rioux
    Department of Public Health and Community Medicine, Tufts University, Boston, Massachusetts 02155, USA
    Environ Health Perspect 118:803-11. 2010
    ..Traffic exposure may increase cardiovascular disease (CVD) risk via systemic inflammation and elevated blood pressure, two important clinical markers for managing disease progression...
  79. doi request reprint Dietary patterns, approaches, and multicultural perspective
    Katherine L Tucker
    Department of Health Sciences, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA
    Appl Physiol Nutr Metab 35:211-8. 2010
    ..Still, dietary pattern research has great potential for use in nutrition policy, particularly as it demonstrates the importance of total diet in health promotion...
  80. doi request reprint Intake of lutein and zeaxanthin differ with age, sex, and ethnicity
    Elizabeth J Johnson
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Am Diet Assoc 110:1357-62. 2010
    ..Our findings suggest that the relative intake of lutein and zeaxanthin may be important to age-related macular degeneration risk. Future studies are needed to assess the individual associations of lutein and zeaxanthin in eye health...
  81. ncbi request reprint The combination of high fruit and vegetable and low saturated fat intakes is more protective against mortality in aging men than is either alone: the Baltimore Longitudinal Study of Aging
    Katherine L Tucker
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
    J Nutr 135:556-61. 2005
    ..In addition, they extend these findings by demonstrating that the combination of both behaviors is more protective than either alone, suggesting that their beneficial effects are mediated by different mechanisms...
  82. ncbi request reprint Hispanic and non-Hispanic white elders from Massachusetts have different patterns of carotenoid intake and plasma concentrations
    Odilia I Bermudez
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Nutr 135:1496-502. 2005
    ..Because of the potential importance of carotenoids as protective factors against chronic diseases, more attention to food-related practices associated with carotenoid intake in differing population groups is warranted...
  83. ncbi request reprint Television viewing is associated with prevalence of metabolic syndrome in Hispanic elders
    Xiang Gao
    Jean Mayer USDA HNRCA at Tufts University, 711 Washington St, Boston, MA 02111 1524, USA
    Diabetes Care 30:694-700. 2007
    ..We examined associations between television viewing and prevalence of the metabolic syndrome among a representative sample of Caribbean-origin Hispanic elders living in Massachusetts...
  84. pmc Plasma B vitamins, homocysteine, and their relation with bone loss and hip fracture in elderly men and women
    Robert R McLean
    Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, Boston, MA 02131, USA
    J Clin Endocrinol Metab 93:2206-12. 2008
    ..Elevated homocysteine is a strong risk factor for osteoporotic fractures among elders, yet it may be a marker for low B-vitamin status...
  85. ncbi request reprint Stress and nutrition in relation to excess development of chronic disease in Puerto Rican adults living in the Northeastern USA
    Katherine L Tucker
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111 1524, USA
    J Med Invest 52:252-8. 2005
    ..We further propose that the association between life stress, physiologic response and chronic conditions is modified by nutritional status, with a focus on B vitamins and antioxidant vitamins...
  86. ncbi request reprint Dietary intake of n-6 fatty acids modulates effect of apolipoprotein A5 gene on plasma fasting triglycerides, remnant lipoprotein concentrations, and lipoprotein particle size: the Framingham Heart Study
    Chao Qiang Lai
    Nutrition and Genomics Laboratory, JM USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Circulation 113:2062-70. 2006
    ..Apolipoprotein A5 gene (APOA5) variation is associated with plasma triglycerides (TGs). However, little is known about whether dietary fat modulates this association...
  87. ncbi request reprint Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: the Framingham Heart Study
    Ernst J Schaefer
    Lipid Metabolism Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tuffs University, Boston, MA 02111, USA
    Arch Neurol 63:1545-50. 2006
    ..Docosahexaenoic acid (DHA) is an abundant fatty acid in the brain. In the diet, DHA is found mostly in fatty fish. The content of DHA has been shown to be decreased in the brain and plasma of patients with dementia...
  88. doi request reprint Drug use and weight loss in HIV-infected Hispanic men
    J E Forrester
    Tufts University School of Medicine, Boston, MA, USA
    AIDS Care 20:868-75. 2008
    ..We conclude that the use of opiates or combined opiates and cocaine does not increase the risk of weight loss in the presence or absence of HIV infection. Exclusive cocaine use may exacerbate weight loss in HIV-infection...
  89. ncbi request reprint Eat a variety of healthful foods: old advice with new support
    K L Tucker
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Nutr Rev 59:156-8. 2001
    ..Studies identifying associations between diet quality and mortality are beginning to quantify the importance of eating a variety of healthful foods and are helping to refine that advice...
  90. ncbi request reprint Relative influence of diet and physical activity on cardiovascular risk factors in urban Chinese adults
    M Yao
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111 1524, USA
    Int J Obes Relat Metab Disord 27:920-32. 2003
    ..We investigated these factors in a population whose traditional diet may have both positive (high plant-based) and negative (high refined carbohydrate) aspects, and whose physical activity levels (PALs) vary widely...
  91. ncbi request reprint Benefits of fatty fish on dementia risk are stronger for those without APOE epsilon4
    T L Huang
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Neurology 65:1409-14. 2005
    ..To compare associations of lean fish vs fatty fish (tuna or other fish) intake with dementia, Alzheimer disease (AD), and vascular dementia (VaD) and in relation to APOE epsilon4 status in the Cardiovascular Health Cognition Study (CHCS)...
  92. ncbi request reprint Television and children's consumption patterns. A review of the literature
    K A Coon
    Nutritional Epidemiology, Jean Mayer USDA Human, Nutrition Research Center on Aging, Tufts University, Boston, USA
    Minerva Pediatr 54:423-36. 2002
    ..The combination of lifestyle factors that accompany heavy television use appear to place children at risk of obesity and poor nutritional status...
  93. ncbi request reprint Nutritional, immunological and health status of the elderly population living in poor neighbourhoods of Quito, Ecuador
    Fernando Sempertegui
    Corporación Ecuatoriana de Biotecnología, Ave Colón 1468 y Nueve de Octubre Of 508, Quito, Ecuador
    Br J Nutr 96:845-53. 2006
    ..In conclusion, while few elderly Ecuadorians were underweight, obesity was common. Micronutrient deficiencies were prevalent and may contribute to reduced immunological responses in this population...
  94. ncbi request reprint Dietary and plasma lipid, lipoprotein, and apolipoprotein profiles among elderly Hispanics and non-Hispanics and their association with diabetes
    Odilia I Bermudez
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 76:1214-21. 2002
    ..There are limited data about dietary intakes and plasma lipids of elderly US Hispanics...
  95. ncbi request reprint High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study
    Katherine L Tucker
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 82:627-35. 2005
    ..It is not clear whether the observed associations between homocysteine and cognitive measures are causal or whether they are due to homocysteine, to independent actions of the B vitamins, or to both...
  96. ncbi request reprint Calcium intake and prostate cancer risk in a long-term aging study: the Baltimore Longitudinal Study of Aging
    Sonja I Berndt
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Urology 60:1118-23. 2002
    ..To investigate the association between prostate cancer and calcium and other nutrients thought to influence the synthesis of 1,25-dihydroxyvitamin D [1,25(OH)2D]...
  97. ncbi request reprint Assessment of usual dietary intake in population studies of gene-diet interaction
    Katherine L Tucker
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Nutr Metab Cardiovasc Dis 17:74-81. 2007
    ..Dietary intake is a critical environmental exposure when considering the effect of many genetic factors on disease risk. However, dietary intake is a complex and changing measure that requires particular care in assessment...
  98. ncbi request reprint Dietary intake and body mass index in HIV-positive and HIV-negative drug abusers of Hispanic ethnicity
    Janet E Forrester
    Department of Familly Medicine and Community Health, Tufts University School of Medicine, Boston, MA 02111, USA
    Public Health Nutr 7:863-70. 2004
    ..Many studies have not considered possible concurrent HIV disease. The purpose of this study was to determine the relationship between drug abuse and dietary intake in Hispanic Americans with and without HIV infection...
  99. ncbi request reprint Association of energy intake with prostate cancer in a long-term aging study: Baltimore Longitudinal Study of Aging (United States)
    Lillian J Hsieh
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Urology 61:297-301. 2003
    ..To examine the association of total energy intake and macronutrient contributors to energy with prostate cancer risk among men in the Baltimore Longitudinal Study of Aging...
  100. pmc Traffic-related particles are associated with elevated homocysteine: the VA normative aging study
    Sung Kyun Park
    Department of Environmental Health Sciences, University of Michigan School of Public Health, 109 S Observatory Street, SPH II M6240, Ann Arbor, MI 48109, USA
    Am J Respir Crit Care Med 178:283-9. 2008
    ..Particulate air pollution has been related to cardiovascular death and hospital admission, but the underlying mechanisms are not fully elucidated...
  101. ncbi request reprint Dietary behaviors, physical activity, and cigarette smoking among pregnant Puerto Rican women
    Audra Gollenberg
    Division of Biostatistics and Epidemiology, Department of Public Health, the School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA, USA
    Am J Clin Nutr 87:1844-51. 2008
    ..Few studies have examined predictors of meeting health guidelines in pregnancy among Latina women...