Lisa M Shin

Summary

Affiliation: Tufts University
Country: USA

Publications

  1. pmc Diminished rostral anterior cingulate cortex activation during trauma-unrelated emotional interference in PTSD
    Reid Offringa
    Department of Psychology, Tufts University, Medford, MA, USA
    Biol Mood Anxiety Disord 3:10. 2013
  2. pmc The neurocircuitry of fear, stress, and anxiety disorders
    Lisa M Shin
    Department of Psychology, Tufts University, Medford, MA 02155, USA
    Neuropsychopharmacology 35:169-91. 2010
  3. ncbi request reprint Hippocampal function in posttraumatic stress disorder
    Lisa M Shin
    Department of Psychology, Tufts University, 490 Boston Avenue, Medford, MA 02155, USA
    Hippocampus 14:292-300. 2004
  4. ncbi request reprint Regional cerebral blood flow in the amygdala and medial prefrontal cortex during traumatic imagery in male and female Vietnam veterans with PTSD
    Lisa M Shin
    Department of Psychology, Tufts University, Medford, MA 02155, USA
    Arch Gen Psychiatry 61:168-76. 2004
  5. pmc Resting metabolic activity in the cingulate cortex and vulnerability to posttraumatic stress disorder
    Lisa M Shin
    Department of Psychology, Tufts University, 490 Boston Ave, Medford, MA 02155, USA
    Arch Gen Psychiatry 66:1099-107. 2009
  6. doi request reprint Is posttraumatic stress disorder a stress-induced fear circuitry disorder?
    Lisa M Shin
    Department of Psychology, Tufts University, Medford, MA 02155, USA
    J Trauma Stress 22:409-15. 2009
  7. ncbi request reprint Amygdala, medial prefrontal cortex, and hippocampal function in PTSD
    Lisa M Shin
    Department of Psychology, Tufts University, 490 Boston Avenue, Medford, MA 02155, USA
    Ann N Y Acad Sci 1071:67-79. 2006
  8. pmc Exaggerated activation of dorsal anterior cingulate cortex during cognitive interference: a monozygotic twin study of posttraumatic stress disorder
    Lisa M Shin
    Department of Psychology, Tufts University, Medford, Mass, USA
    Am J Psychiatry 168:979-85. 2011
  9. ncbi request reprint Dorsal anterior cingulate function in posttraumatic stress disorder
    Lisa M Shin
    Department of Psychology, Tufts University, Medford, MA 02155, USA
    J Trauma Stress 20:701-12. 2007
  10. ncbi request reprint A functional magnetic resonance imaging study of amygdala and medial prefrontal cortex responses to overtly presented fearful faces in posttraumatic stress disorder
    Lisa M Shin
    Department of Psychology, Tufts University, Medford, Mass, USA
    Arch Gen Psychiatry 62:273-81. 2005

Detail Information

Publications36

  1. pmc Diminished rostral anterior cingulate cortex activation during trauma-unrelated emotional interference in PTSD
    Reid Offringa
    Department of Psychology, Tufts University, Medford, MA, USA
    Biol Mood Anxiety Disord 3:10. 2013
    ..The present study employed functional magnetic resonance imaging (fMRI) and an interference task that involves emotional facial expressions and elicits rACC activation in healthy participants...
  2. pmc The neurocircuitry of fear, stress, and anxiety disorders
    Lisa M Shin
    Department of Psychology, Tufts University, Medford, MA 02155, USA
    Neuropsychopharmacology 35:169-91. 2010
    ....
  3. ncbi request reprint Hippocampal function in posttraumatic stress disorder
    Lisa M Shin
    Department of Psychology, Tufts University, 490 Boston Avenue, Medford, MA 02155, USA
    Hippocampus 14:292-300. 2004
    ....
  4. ncbi request reprint Regional cerebral blood flow in the amygdala and medial prefrontal cortex during traumatic imagery in male and female Vietnam veterans with PTSD
    Lisa M Shin
    Department of Psychology, Tufts University, Medford, MA 02155, USA
    Arch Gen Psychiatry 61:168-76. 2004
    ..However, the functional relationship between these brain regions in PTSD has not been directly examined...
  5. pmc Resting metabolic activity in the cingulate cortex and vulnerability to posttraumatic stress disorder
    Lisa M Shin
    Department of Psychology, Tufts University, 490 Boston Ave, Medford, MA 02155, USA
    Arch Gen Psychiatry 66:1099-107. 2009
    ..Recent neuroimaging research has revealed functional abnormalities in the anterior cingulate cortex, amygdala, and hippocampus in individuals with posttraumatic stress disorder (PTSD)...
  6. doi request reprint Is posttraumatic stress disorder a stress-induced fear circuitry disorder?
    Lisa M Shin
    Department of Psychology, Tufts University, Medford, MA 02155, USA
    J Trauma Stress 22:409-15. 2009
    ..Implications for future diagnostic classifications are discussed...
  7. ncbi request reprint Amygdala, medial prefrontal cortex, and hippocampal function in PTSD
    Lisa M Shin
    Department of Psychology, Tufts University, 490 Boston Avenue, Medford, MA 02155, USA
    Ann N Y Acad Sci 1071:67-79. 2006
    ..Lastly, the reviewed research suggests diminished volumes, neuronal integrity, and functional integrity of the hippocampus in PTSD. Remaining research questions and related future directions are presented...
  8. pmc Exaggerated activation of dorsal anterior cingulate cortex during cognitive interference: a monozygotic twin study of posttraumatic stress disorder
    Lisa M Shin
    Department of Psychology, Tufts University, Medford, Mass, USA
    Am J Psychiatry 168:979-85. 2011
    ..The goal of this study was to determine whether hyperresponsivity of the dorsal anterior cingulate in PTSD is an acquired characteristic or a familial risk factor...
  9. ncbi request reprint Dorsal anterior cingulate function in posttraumatic stress disorder
    Lisa M Shin
    Department of Psychology, Tufts University, Medford, MA 02155, USA
    J Trauma Stress 20:701-12. 2007
  10. ncbi request reprint A functional magnetic resonance imaging study of amygdala and medial prefrontal cortex responses to overtly presented fearful faces in posttraumatic stress disorder
    Lisa M Shin
    Department of Psychology, Tufts University, Medford, Mass, USA
    Arch Gen Psychiatry 62:273-81. 2005
    ..Previous functional neuroimaging studies have demonstrated exaggerated amygdala responses and diminished medial prefrontal cortex responses during the symptomatic state in posttraumatic stress disorder (PTSD)...
  11. doi request reprint The neural correlates of emotional memory in posttraumatic stress disorder
    Kathryn Handwerger Brohawn
    Department of Psychology, Tufts University, Medford, Massachusetts 02155, USA
    Biol Psychiatry 68:1023-30. 2010
    ..As the functional integrity of these regions may be compromised in PTSD, the current study examined the neural correlates of emotional memory in PTSD...
  12. pmc Amygdala and fusiform gyrus temporal dynamics: responses to negative facial expressions
    Jennifer C Britton
    Psychiatric Neuroimaging Research Program and Martinos Biomedical Imaging Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    BMC Neurosci 9:44. 2008
    ..Percent signal changes within anatomic regions-of-interest (amygdala and fusiform gyrus) were calculated to examine the temporal dynamics of neural response and any response differences based on face type...
  13. doi request reprint Threat facilitates subsequent executive control during anxious mood
    Jeffrey L Birk
    Department of Psychology, Tufts University, Medford, MA 02155, USA
    Emotion 11:1291-304. 2011
    ..The findings are partially consistent with the predictions of DCF in that low-level threat improved executive control, at least during a state of anxiety...
  14. ncbi request reprint Predictors of fluvoxamine response in contamination-related obsessive compulsive disorder: a PET symptom provocation study
    Scott L Rauch
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Neuropsychopharmacology 27:782-91. 2002
    ..Finally, this pattern is sufficiently robust as to be relatively independent of symptomatic state at the time of tracer uptake...
  15. doi request reprint Mood-induced shifts in attentional bias to emotional information predict ill- and well-being
    Sarah R Cavanagh
    Department of Psychology, Assumption College, Worcester, MA 01609, USA
    Emotion 11:241-8. 2011
    ....
  16. ncbi request reprint Psychiatric and emotional sequelae of surgical amputation
    Sarah R Cavanagh
    Department of Psychology, Tufts University, Medford, MA, USA
    Psychosomatics 47:459-64. 2006
    ..In contrast, data suggest that amputation resulting from accidental injury may lead to a higher prevalence of PTSD, in part because of the emotional stress surrounding the accident...
  17. pmc Functional neuroimaging studies of post-traumatic stress disorder
    Katherine C Hughes
    Department of Psychology, Tufts University, MA, USA
    Expert Rev Neurother 11:275-85. 2011
    ..We will then review functional neuroimaging studies that have reported significant findings in the amygdala, medial prefrontal cortex, hippocampus and insula. Finally, we will suggest future directions for research...
  18. ncbi request reprint Ventromedial prefrontal cortex and amygdala dysfunction during an anger induction positron emission tomography study in patients with major depressive disorder with anger attacks
    Darin D Dougherty
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA
    Arch Gen Psychiatry 61:795-804. 2004
    ....
  19. ncbi request reprint Increased medial temporal lobe activation during the passive viewing of emotional and neutral facial expressions in schizophrenia
    Daphne J Holt
    Massachusetts General Hospital, Department of Psychiatry, Harvard Medical School, Boston, MA 02129, USA
    Schizophr Res 82:153-62. 2006
    ..Here we tested whether MTL responses to human faces in schizophrenia are abnormal when unconstrained by a cognitive task and measured relative to a low-level baseline (fixation) condition...
  20. pmc Neurobiological basis of failure to recall extinction memory in posttraumatic stress disorder
    Mohammed R Milad
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02129, USA
    Biol Psychiatry 66:1075-82. 2009
    ..amygdala, hippocampus, ventromedial prefrontal cortex (vmPFC), and dorsal anterior cingulate cortex (dACC)...
  21. ncbi request reprint Neuroimaging studies of amygdala function in anxiety disorders
    Scott L Rauch
    Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02129, USA
    Ann N Y Acad Sci 985:389-410. 2003
    ..We conclude that such tools hold great promise for facilitating progress in relevant basic neuroscience as well as clinical research domains...
  22. pmc Emotion and cognition interactions in PTSD: a review of neurocognitive and neuroimaging studies
    Jasmeet P Hayes
    National Center for PTSD, VA Boston Healthcare System Boston, MA, USA Department of Psychiatry, Boston University School of Medicine Boston, MA, USA
    Front Integr Neurosci 6:89. 2012
    ..The results are reviewed to provide future directions for research that may direct better and more effective treatments for PTSD...
  23. ncbi request reprint Functional magnetic resonance imaging study of regional brain activation during implicit sequence learning in obsessive-compulsive disorder
    Scott L Rauch
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02129, USA
    Biol Psychiatry 61:330-6. 2007
    ..Here, we used the SRT and functional magnetic resonance imaging (fMRI) to replicate prior results in a larger sample and to test for relationships between regional activation and OCD symptom dimensions...
  24. doi request reprint Functional magnetic resonance imaging of methylphenidate and placebo in attention-deficit/hyperactivity disorder during the multi-source interference task
    George Bush
    Departments of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
    Arch Gen Psychiatry 65:102-14. 2008
    ..Stimulant medications are effective treatments for ADHD, but their neural effects have not been fully characterized...
  25. ncbi request reprint Brain habituation during repeated exposure to fearful and neutral faces: a functional MRI study
    Hakan Fischer
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA
    Brain Res Bull 59:387-92. 2003
    ..These results indicate that brain regions involved in novelty detection and memory processing habituate at similar rates regardless of whether the face in focus displays an aversive emotional expression or not...
  26. ncbi request reprint Neurocircuitry models of posttraumatic stress disorder and extinction: human neuroimaging research--past, present, and future
    Scott L Rauch
    Psychiatric Neuroscience Division, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, USA
    Biol Psychiatry 60:376-82. 2006
    ..The recent development of such imaging probes now sets the stage for directly testing hypotheses regarding the neural substrates of fear conditioning and extinction abnormalities in PTSD...
  27. ncbi request reprint Enhanced amygdala responses to emotional versus neutral schematic facial expressions
    Christopher I Wright
    Psychiatric Neuroimaging Research Group and Nuclear Magnetic Resonance Center, Massachusetts General Hospital, Harvard Medical School, 13th St, Bldg 149, CNY 9, Charlestown, MA 02129, USA
    Neuroreport 13:785-90. 2002
    ....
  28. ncbi request reprint A magnetic resonance imaging study of cortical thickness in animal phobia
    Scott L Rauch
    Department of Psychiatry, Massachusetts General Hospital East, 2nd Floor, Building 149, 13th Street, Charlestown, MA 02129, USA
    Biol Psychiatry 55:946-52. 2004
    ....
  29. ncbi request reprint Amygdala and insular responses to emotionally valenced human faces in small animal specific phobia
    Christopher I Wright
    Psychiatric Neuroimaging Research Group and Nuclear Magnetic Resonance Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Biol Psychiatry 54:1067-76. 2003
    ..However, it is not clear to what extent this concept applies across anxiety disorders. Several studies have examined brain function in specific phobias but did not demonstrate amygdala responses or use specific probes of the amygdala...
  30. ncbi request reprint Amygdala responses to human faces in obsessive-compulsive disorder
    Paul A Cannistraro
    Psychiatric Neuroimaging Research Program, Department of Psychiatry, Massachusetts General Hospital, Building 149, Thirteenth Street, Charlestown, MA 02129, USA
    Biol Psychiatry 56:916-20. 2004
    ..To assess the amygdala response to emotional faces in obsessive-compulsive disorder (OCD) using functional magnetic resonance imaging (fMRI)...
  31. ncbi request reprint Selectively reduced regional cortical volumes in post-traumatic stress disorder
    Scott L Rauch
    Psychiatric Neuroimaging Research Group, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, 13th St, Bldg 149, CNY 9, Charlestown, MA 02129, USA
    Neuroreport 14:913-6. 2003
    ..These results are consistent with contemporary schemes regarding functional and structural dissection of frontal cortex, and suggest specific regional cortical pathology in PTSD...
  32. ncbi request reprint Differential amygdalar response to novel versus newly familiar neutral faces: a functional MRI probe developed for studying inhibited temperament
    Carl E Schwartz
    Developmental Psychopathology Research Group CES, Massachusetts General Hospital, Charlestown 02129, USA
    Biol Psychiatry 53:854-62. 2003
    ..Prior neuroimaging studies of the amygdala in humans to date have focused principally on responses to emotional stimuli, primarily aversive, rather than to novelty per se...
  33. ncbi request reprint Novelty responses and differential effects of order in the amygdala, substantia innominata, and inferior temporal cortex
    Christopher I Wright
    Psychiatric Neuroimaging Research Group, Massachusetts General Hospital, Harvard Medical School, 13th St, Bldg 149, CNY 9, Charlestown, MA 02129, USA
    Neuroimage 18:660-9. 2003
    ....
  34. ncbi request reprint Contextual modulation of amygdala responsivity to surprised faces
    Hackjin Kim
    University of Wisconsin Madison, Madison, WI 53705, USA
    J Cogn Neurosci 16:1730-45. 2004
    ..Connectivity analyses identified candidate cortical-subcortical systems subserving this modulation...
  35. ncbi request reprint Functional neuroimaging studies of the amygdala in depression
    Paul J Whalen
    Department of Psychiatry, W M Keck Laboratory for Functional Brain Imaging and Behavior, University of Wisconsin, Madison, WI 53705, USA
    Semin Clin Neuropsychiatry 7:234-42. 2002
    ..Furthermore, we suggest that the scope of the amygdala's involvement may go beyond its well-known role in fear to its more subtle and generalized role in modulating moment-to-moment vigilance levels...
  36. ncbi request reprint Inhibited and uninhibited infants "grown up": adult amygdalar response to novelty
    Carl E Schwartz
    Developmental Psychopathology Research Group, Department of Psychiatry, Massachusetts General Hospital MGH, Harvard Medical School, 13th Street, Building 149, CNY 9, Charlestown, MA 02129, USA
    Science 300:1952-3. 2003
    ....