Research Topics
| Lisa M ShinSummaryAffiliation: Tufts University Country: USA Publications
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Detail Information
Publications
Amygdala and fusiform gyrus temporal dynamics: responses to negative facial expressionsJennifer C Britton
Psychiatric Neuroimaging Research Program and Martinos Biomedical Imaging Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
BMC Neurosci 9:44. 2008..Percent signal changes within anatomic regions-of-interest (amygdala and fusiform gyrus) were calculated to examine the temporal dynamics of neural response and any response differences based on face type...- The neurocircuitry of fear, stress, and anxiety disordersLisa M Shin
Department of Psychology, Tufts University, Medford, MA 02155, USA
Neuropsychopharmacology 35:169-91. 2010.... 
Exaggerated activation of dorsal anterior cingulate cortex during cognitive interference: a monozygotic twin study of posttraumatic stress disorderLisa M Shin
Department of Psychology, Tufts University, Medford, Mass, USA
Am J Psychiatry 168:979-85. 2011..The goal of this study was to determine whether hyperresponsivity of the dorsal anterior cingulate in PTSD is an acquired characteristic or a familial risk factor...
Amygdala, medial prefrontal cortex, and hippocampal function in PTSDLisa M Shin
Department of Psychology, Tufts University, 490 Boston Avenue, Medford, MA 02155, USA
Ann N Y Acad Sci 1071:67-79. 2006..Lastly, the reviewed research suggests diminished volumes, neuronal integrity, and functional integrity of the hippocampus in PTSD. Remaining research questions and related future directions are presented...- Hippocampal function in posttraumatic stress disorderLisa M Shin
Department of Psychology, Tufts University, 490 Boston Avenue, Medford, MA 02155, USA
Hippocampus 14:292-300. 2004.... - Dorsal anterior cingulate function in posttraumatic stress disorderLisa M Shin
Department of Psychology, Tufts University, Medford, MA 02155, USA
J Trauma Stress 20:701-12. 2007 - Resting metabolic activity in the cingulate cortex and vulnerability to posttraumatic stress disorderLisa M Shin
Department of Psychology, Tufts University, 490 Boston Ave, Medford, MA 02155, USA
Arch Gen Psychiatry 66:1099-107. 2009..Recent neuroimaging research has revealed functional abnormalities in the anterior cingulate cortex, amygdala, and hippocampus in individuals with posttraumatic stress disorder (PTSD)... - Regional cerebral blood flow in the amygdala and medial prefrontal cortex during traumatic imagery in male and female Vietnam veterans with PTSDLisa M Shin
Department of Psychology, Tufts University, Medford, MA 02155, USA
Arch Gen Psychiatry 61:168-76. 2004..However, the functional relationship between these brain regions in PTSD has not been directly examined... - Is posttraumatic stress disorder a stress-induced fear circuitry disorder?Lisa M Shin
Department of Psychology, Tufts University, Medford, MA 02155, USA
J Trauma Stress 22:409-15. 2009..Implications for future diagnostic classifications are discussed... - A functional magnetic resonance imaging study of amygdala and medial prefrontal cortex responses to overtly presented fearful faces in posttraumatic stress disorderLisa M Shin
Department of Psychology, Tufts University, Medford, Mass, USA
Arch Gen Psychiatry 62:273-81. 2005.... - Threat facilitates subsequent executive control during anxious moodJeffrey L Birk
Department of Psychology, Tufts University, Medford, MA 02155, USA
Emotion 11:1291-304. 2011..The findings are partially consistent with the predictions of DCF in that low-level threat improved executive control, at least during a state of anxiety... - The neural correlates of emotional memory in posttraumatic stress disorderKathryn Handwerger Brohawn
Department of Psychology, Tufts University, Medford, Massachusetts 02155, USA
Biol Psychiatry 68:1023-30. 2010..As the functional integrity of these regions may be compromised in PTSD, the current study examined the neural correlates of emotional memory in PTSD... - Mood-induced shifts in attentional bias to emotional information predict ill- and well-beingSarah R Cavanagh
Department of Psychology, Assumption College, Worcester, MA 01609, USA
Emotion 11:241-8. 2011.... - Functional neuroimaging studies of post-traumatic stress disorderKatherine C Hughes
Department of Psychology, Tufts University, MA, USA
Expert Rev Neurother 11:275-85. 2011..We will then review functional neuroimaging studies that have reported significant findings in the amygdala, medial prefrontal cortex, hippocampus and insula. Finally, we will suggest future directions for research... - Ventromedial prefrontal cortex and amygdala dysfunction during an anger induction positron emission tomography study in patients with major depressive disorder with anger attacksDarin D Dougherty
Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA
Arch Gen Psychiatry 61:795-804. 2004.... - Psychiatric and emotional sequelae of surgical amputationSarah R Cavanagh
Department of Psychology, Tufts University, Medford, MA, USA
Psychosomatics 47:459-64. 2006..In contrast, data suggest that amputation resulting from accidental injury may lead to a higher prevalence of PTSD, in part because of the emotional stress surrounding the accident... - Neurobiological basis of failure to recall extinction memory in posttraumatic stress disorderMohammed R Milad
Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02129, USA
Biol Psychiatry 66:1075-82. 2009..amygdala, hippocampus, ventromedial prefrontal cortex (vmPFC), and dorsal anterior cingulate cortex (dACC)... - Increased medial temporal lobe activation during the passive viewing of emotional and neutral facial expressions in schizophreniaDaphne J Holt
Massachusetts General Hospital, Department of Psychiatry, Harvard Medical School, Boston, MA 02129, USA
Schizophr Res 82:153-62. 2006..Here we tested whether MTL responses to human faces in schizophrenia are abnormal when unconstrained by a cognitive task and measured relative to a low-level baseline (fixation) condition... - Predictors of fluvoxamine response in contamination-related obsessive compulsive disorder: a PET symptom provocation studyScott L Rauch
Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
Neuropsychopharmacology 27:782-91. 2002..Finally, this pattern is sufficiently robust as to be relatively independent of symptomatic state at the time of tracer uptake... - Neuroimaging studies of amygdala function in anxiety disordersScott L Rauch
Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02129, USA
Ann N Y Acad Sci 985:389-410. 2003..We conclude that such tools hold great promise for facilitating progress in relevant basic neuroscience as well as clinical research domains... - Functional magnetic resonance imaging study of regional brain activation during implicit sequence learning in obsessive-compulsive disorderScott L Rauch
Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02129, USA
Biol Psychiatry 61:330-6. 2007..Here, we used the SRT and functional magnetic resonance imaging (fMRI) to replicate prior results in a larger sample and to test for relationships between regional activation and OCD symptom dimensions... - Brain habituation during repeated exposure to fearful and neutral faces: a functional MRI studyHakan Fischer
Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA
Brain Res Bull 59:387-92. 2003..These results indicate that brain regions involved in novelty detection and memory processing habituate at similar rates regardless of whether the face in focus displays an aversive emotional expression or not... - Functional magnetic resonance imaging of methylphenidate and placebo in attention-deficit/hyperactivity disorder during the multi-source interference taskGeorge Bush
Departments of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
Arch Gen Psychiatry 65:102-14. 2008..Stimulant medications are effective treatments for ADHD, but their neural effects have not been fully characterized... - Enhanced amygdala responses to emotional versus neutral schematic facial expressionsChristopher I Wright
Psychiatric Neuroimaging Research Group and Nuclear Magnetic Resonance Center, Massachusetts General Hospital, Harvard Medical School, 13th St, Bldg 149, CNY-9, Charlestown, MA 02129, USA
Neuroreport 13:785-90. 2002.... - Neurocircuitry models of posttraumatic stress disorder and extinction: human neuroimaging research--past, present, and futureScott L Rauch
Psychiatric Neuroscience Division, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, USA
Biol Psychiatry 60:376-82. 2006..The recent development of such imaging probes now sets the stage for directly testing hypotheses regarding the neural substrates of fear conditioning and extinction abnormalities in PTSD... - Amygdala and insular responses to emotionally valenced human faces in small animal specific phobiaChristopher I Wright
Psychiatric Neuroimaging Research Group and Nuclear Magnetic Resonance Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
Biol Psychiatry 54:1067-76. 2003..g., posttraumatic stress disorder). This suggests a restricted role for the amygdala in specific phobia. The insular hyperresponsivity to fearful versus neutral faces in the subjects with specific phobias warrants further study... - Functional neuroimaging studies of the amygdala in depressionPaul J Whalen
Department of Psychiatry, W M Keck Laboratory for Functional Brain Imaging and Behavior, University of Wisconsin, Madison, WI 53705, USA
Semin Clin Neuropsychiatry 7:234-42. 2002..Furthermore, we suggest that the scope of the amygdala's involvement may go beyond its well-known role in fear to its more subtle and generalized role in modulating moment-to-moment vigilance levels... - Contextual modulation of amygdala responsivity to surprised facesHackjin Kim
University of Wisconsin-Madison, Madison, WI 53705, USA
J Cogn Neurosci 16:1730-45. 2004..Connectivity analyses identified candidate cortical-subcortical systems subserving this modulation... - Novelty responses and differential effects of order in the amygdala, substantia innominata, and inferior temporal cortexChristopher I Wright
Psychiatric Neuroimaging Research Group, Massachusetts General Hospital, Harvard Medical School, 13th St, Bldg 149, CNY 9, Charlestown, MA 02129, USA
Neuroimage 18:660-9. 2003.... - Amygdala responses to human faces in obsessive-compulsive disorderPaul A Cannistraro
Psychiatric Neuroimaging Research Program, Department of Psychiatry, Massachusetts General Hospital, Building 149, Thirteenth Street, Charlestown, MA 02129, USA
Biol Psychiatry 56:916-20. 2004..Therefore, the present findings are consistent with abnormal amygdala function in OCD and are of a character that may distinguish OCD from other anxiety disorders... - Differential amygdalar response to novel versus newly familiar neutral faces: a functional MRI probe developed for studying inhibited temperamentCarl E Schwartz
Developmental Psychopathology Research Group (CES, Massachusetts General Hospital, Charlestown 02129, USA
Biol Psychiatry 53:854-62. 2003..We propose that this experimental paradigm will be useful for examining brain responses to novelty in different temperamental groups, as well as various psychiatric disorders... - A magnetic resonance imaging study of cortical thickness in animal phobiaScott L Rauch
Department of Psychiatry, Massachusetts General Hospital-East, 2nd Floor, Building 149, 13th Street, Charlestown, MA 02129, USA
Biol Psychiatry 55:946-52. 2004..Further research will be necessary to replicate these findings and to determine their specificity as well as their pathophysiologic significance... - Inhibited and uninhibited infants "grown up": adult amygdalar response to noveltyCarl E Schwartz
Developmental Psychopathology Research Group, Department of Psychiatry, Massachusetts General Hospital MGH, Harvard Medical School, 13th Street, Building 149, CNY 9, Charlestown, MA 02129, USA
Science 300:1952-3. 2003.... - Selectively reduced regional cortical volumes in post-traumatic stress disorderScott L Rauch
Psychiatric Neuroimaging Research Group, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, 13th St, Bldg 149, CNY 9, Charlestown, MA 02129, USA
Neuroreport 14:913-6. 2003..These results are consistent with contemporary schemes regarding functional and structural dissection of frontal cortex, and suggest specific regional cortical pathology in PTSD...