Affiliation: Tufts Medical Center
- Frequency of and risk factors for poor cognitive performance in hemodialysis patientsMark J Sarnak
Division of Nephrology, Tufts Medical Center, Boston, MA, USA
Neurology 80:471-80. 2013..There are few detailed data on cognition in patients undergoing dialysis. We evaluated the frequency of and risk factors for poor cognitive performance using detailed neurocognitive testing...
- Filtration markers may have prognostic value independent of glomerular filtration rateNavdeep Tangri
Department of Medicine, Division of Nephrology, Tufts Medical Center, Boston, MA 02111, USA
J Am Soc Nephrol 23:351-9. 2012..trace protein and cystatin C seem to provide more consistent prognostic information than creatinine...
- CKD classification based on estimated GFR over three years and subsequent cardiac and mortality outcomes: a cohort studyDaniel E Weiner
Division of Nephrology, Tufts Medical Center, 800 Washington Street, Boston, MA 02111, USA
BMC Nephrol 10:26. 2009..It is unknown whether defining chronic kidney disease (CKD) based on one versus two estimated glomerular filtration rate (eGFR) assessments changes the prognostic importance of reduced eGFR in a community-based population...
- Implications of proteinuria: CKD progression and cardiovascular outcomesMark J Sarnak
Division of Nephrology, Department of Medicine, Tufts Medical Center, Boston, MA 02111, USA
Adv Chronic Kidney Dis 18:258-66. 2011..Finally, we provide some theories as to why proteinuria may be a risk factor for development of CVD...
- Predictors of sudden cardiac death: a competing risk approach in the hemodialysis studyShani Shastri
Division of Nephrology, Tufts Medical Center, 800 Washington Street, Box 391, Boston, MA 02111, USA
Clin J Am Soc Nephrol 7:123-30. 2012..The study objective was to identify predictors associated with various causes of death in the Hemodialysis (HEMO) Study and to develop a prediction model for SCD using a competing risk approach...
- Racial and ethnic differences in kidney function decline among persons without chronic kidney diseaseCarmen A Peralta
Department of Medicine, University of California San Francisco, San Francisco, California 94121, USA
J Am Soc Nephrol 22:1327-34. 2011..Traditional risk factors do not explain these differences fully, highlighting the need to explore these disparities...
- Association of arterial rigidity with incident kidney disease and kidney function decline: the Health ABC studyMagdalena Madero
Department of Medicine, Division of Nephrology, National Heart Institute, Mexico City, Mexico
Clin J Am Soc Nephrol 8:424-33. 2013..This study evaluated the association of aortic pulse wave velocity (aPWV) and pulse pressure (PP) with rapid kidney function decline and incident CKD in the Health, Aging and Body Composition study...
- The Nutrition, Aging, and Memory in Elders (NAME) study: design and methods for a study of micronutrients and cognitive function in a homebound elderly populationTammy M Scott
Tufts New England Medical Center, Boston, MA 02111, USA
Int J Geriatr Psychiatry 21:519-28. 2006..Understanding mediating factors by which micronutrient status affects cognitive function would contribute to elders' quality of life and their ability to remain in the home...
- Inflammation, oxidative stress, and insulin resistance in polycystic kidney diseaseVandana Menon
Division of Nephrology, Tufts Medical Center, Boston, Massachusetts, USA
Clin J Am Soc Nephrol 6:7-13. 2011..Most deaths in autosomal dominant polycystic kidney disease (ADPKD) are attributable to cardiovascular disease (CVD). We examined novel CVD biomarkers in different stages of ADPKD...
- Low 25-hydroxyvitamin D levels and cognitive impairment in hemodialysis patientsKamran Shaffi
Division of Nephrology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts 02111, USA
Clin J Am Soc Nephrol 8:979-86. 2013..This study tested the hypothesis that 25(OH)D deficiency may be associated with cognitive impairment because of its vasculoprotective, neuroprotective, and immune-modulatory properties...
- Cystatin C and subclinical brain infarctionStephen L Seliger
Division of Nephrology, University of Maryland, Baltimore, MD 21201, USA
J Am Soc Nephrol 16:3721-7. 2005..Compared with creatinine, CysC, a novel marker of renal function, has a stronger and more direct association with SBI in the elderly...
- Chronic kidney disease in octogenariansShani Shastri
Tufts Medical Center, Boston, MA 02111, USA
Clin J Am Soc Nephrol 6:1410-7. 2011..There are limited data on the prevalence of chronic kidney disease (CKD) and its clinical importance in the very old. We examined the prevalence of CKD in octogenarians and its association with cardiovascular disease (CVD)...
- Does Kidney Function Determine Aging SuccessMark Sarnak; Fiscal Year: 2007..The goal of this application is to evaluate whether cystatin-C is associated with complications of aging. If so, preservation of kidney function may be key to successful aging. ..
- Cognition and DialysisMark Sarnak; Fiscal Year: 2009....
- Cognition and DialysisMark J Sarnak; Fiscal Year: 2010....