I H Rosenberg

Summary

Affiliation: Tufts University
Country: USA

Publications

  1. ncbi request reprint Challenges and opportunities in the translation of the science of vitamins
    Irwin H Rosenberg
    Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 85:325S-7S. 2007
  2. ncbi request reprint Further evidence that food fortification improves micronutrient status
    Irwin H Rosenberg
    Friedman School of Nutrition, Science and Policy, Tufts University, Boston, USA
    Br J Nutr 97:1051-2. 2007
  3. ncbi request reprint Effects of folate and vitamin B12 on cognitive function in adults and the elderly
    Irwin H Rosenberg
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    Food Nutr Bull 29:S132-42. 2008
  4. ncbi request reprint Nutritional enhancement of US Title II food aid products
    Irwin Rosenberg
    Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA
    Food Nutr Bull 32:S134-51. 2011
  5. doi request reprint Sarcopenia: origins and clinical relevance
    Irwin H Rosenberg
    Tufts University, Jaharis Building, Boston, MA 02111, USA
    Clin Geriatr Med 27:337-9. 2011
  6. ncbi request reprint Metabolic programming of offspring by vitamin B12/folate imbalance during pregnancy
    I H Rosenberg
    Friedman School of Nutrition Science and Policy, Tufts University, 150 Harrison Avenue, Boston, MA 02111, USA
    Diabetologia 51:6-7. 2008
  7. doi request reprint Translating nutrition science into policy as witness and actor
    Irwin H Rosenberg
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
    Annu Rev Nutr 28:1-12. 2008
  8. ncbi request reprint Interdepartmental Committee on Nutrition for National Defense surveys in Asia and Africa
    Irwin H Rosenberg
    Tufts University Friedman School of Nutrition Science and Policy, Boston, MA, USA
    J Nutr 135:1272-5. 2005
  9. ncbi request reprint Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort
    P F Jacques
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    Am J Clin Nutr 73:613-21. 2001
  10. ncbi request reprint Relationship between plasma homocysteine and vitamin status in the Framingham study population. Impact of folic acid fortification
    J Selhub
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    Public Health Rev 28:117-45. 2000

Research Grants

  1. Micronutrients, stroke and cognition in aging
    Irwin Rosenberg; Fiscal Year: 2006
  2. Renal Transplantation, Homocysteine Lowering & Cognition
    Irwin Rosenberg; Fiscal Year: 2007

Collaborators

Detail Information

Publications72

  1. ncbi request reprint Challenges and opportunities in the translation of the science of vitamins
    Irwin H Rosenberg
    Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 85:325S-7S. 2007
    ..At its best, all of these disparate types of research will require a robust interaction between the public and private sectors in a regulatory framework that supports and rewards investment in good science...
  2. ncbi request reprint Further evidence that food fortification improves micronutrient status
    Irwin H Rosenberg
    Friedman School of Nutrition, Science and Policy, Tufts University, Boston, USA
    Br J Nutr 97:1051-2. 2007
  3. ncbi request reprint Effects of folate and vitamin B12 on cognitive function in adults and the elderly
    Irwin H Rosenberg
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    Food Nutr Bull 29:S132-42. 2008
  4. ncbi request reprint Nutritional enhancement of US Title II food aid products
    Irwin Rosenberg
    Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA
    Food Nutr Bull 32:S134-51. 2011
    ..This article presents findings and recommendations of that review relating to product enhancements...
  5. doi request reprint Sarcopenia: origins and clinical relevance
    Irwin H Rosenberg
    Tufts University, Jaharis Building, Boston, MA 02111, USA
    Clin Geriatr Med 27:337-9. 2011
    ....
  6. ncbi request reprint Metabolic programming of offspring by vitamin B12/folate imbalance during pregnancy
    I H Rosenberg
    Friedman School of Nutrition Science and Policy, Tufts University, 150 Harrison Avenue, Boston, MA 02111, USA
    Diabetologia 51:6-7. 2008
  7. doi request reprint Translating nutrition science into policy as witness and actor
    Irwin H Rosenberg
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
    Annu Rev Nutr 28:1-12. 2008
    ..My current interest in world hunger and famine and their impact on human security may circle back to studies of the great Bengal famine and the first Bangladesh survey of malnutrition...
  8. ncbi request reprint Interdepartmental Committee on Nutrition for National Defense surveys in Asia and Africa
    Irwin H Rosenberg
    Tufts University Friedman School of Nutrition Science and Policy, Boston, MA, USA
    J Nutr 135:1272-5. 2005
    ..S. domestic survey outside of an Indian reservation, culminating in the Ten State Nutrition Survey (5), which documented that there was hunger in America, as well as abroad...
  9. ncbi request reprint Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort
    P F Jacques
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    Am J Clin Nutr 73:613-21. 2001
    ..Established determinants of fasting total homocysteine (tHcy) concentration include folate and vitamin B-12 status, serum creatinine concentration, and renal function...
  10. ncbi request reprint Relationship between plasma homocysteine and vitamin status in the Framingham study population. Impact of folic acid fortification
    J Selhub
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    Public Health Rev 28:117-45. 2000
    ..The impact of fortification on the US population is likely to be similar; however it awaits the next survey for further confirmation...
  11. ncbi request reprint Hyperhomocysteinemia and hypercholesterolemia associated with hypothyroidism in the third US National Health and Nutrition Examination Survey
    M S Morris
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Atherosclerosis 155:195-200. 2001
    ..Hyperhomocysteinemia and hypercholesterolemia could help to explain the increased risk for arteriosclerotic coronary artery disease in hypothyroidism...
  12. ncbi request reprint Total homocysteine and estrogen status indicators in the Third National Health and Nutrition Examination Survey
    M S Morris
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Epidemiol 152:140-8. 2000
    ....
  13. pmc 25-Hydroxyvitamin D, dementia, and cerebrovascular pathology in elders receiving home services
    J S Buell
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington St, Boston, MA 02111, USA
    Neurology 74:18-26. 2010
    ..However, no studies have examined the association between vitamin D status, dementia, and cranial MRI indicators of cerebrovascular disease (CVD)...
  14. ncbi request reprint Low circulating vitamin B(6) is associated with elevation of the inflammation marker C-reactive protein independently of plasma homocysteine levels
    S Friso
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Circulation 103:2788-91. 2001
    ..This observation may reflect a vitamin B(6) utilization in the presence of an underlying inflammatory process and represent a possible mechanism to explain the decreased vitamin B(6) levels in CVD...
  15. ncbi request reprint Serum total homocysteine concentrations in adolescent and adult Americans: results from the third National Health and Nutrition Examination Survey
    P F Jacques
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 69:482-9. 1999
    ..The elevation of circulating total homocysteine concentrations in a fasting state is associated with an increased risk of occlusive vascular disease...
  16. ncbi request reprint Plasma 25-hydroxyvitamin D and its determinants in an elderly population sample
    P F Jacques
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 66:929-36. 1997
    ..Results from this population-based sample of elderly individuals suggest that inadequate vitamin D status is an important public health problem, which could be readily addressed by adequate vitamin D intake or sunlight exposure...
  17. ncbi request reprint Folic acid fortification increases red blood cell folate concentrations in the Framingham study
    S F Choumenkovitch
    Vitamin Metabolism and Aging Laboratory, and Epidemiology Program, Jean Mayer U.S. Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Nutr 131:3277-80. 2001
    ..The results of this study showed that in this cohort, the introduction of folic acid fortification significantly improved folate nutritional status measured as RBC folate...
  18. ncbi request reprint Nonfasting plasma total homocysteine levels and all-cause and cardiovascular disease mortality in elderly Framingham men and women
    A G Bostom
    Tufts Jean Mayer USDA Human Nutrition Research Center on Aging, Boston, Mass, USA
    Arch Intern Med 159:1077-80. 1999
    ..We examined whether elevated fasting plasma tHcy levels were predictive of all-cause and CVD mortality in a large, population-based sample of elderly US women and men...
  19. pmc MAT1A variants are associated with hypertension, stroke, and markers of DNA damage and are modulated by plasma vitamin B-6 and folate
    Chao Qiang Lai
    Nutrition and Genomics Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 91:1377-86. 2010
    ..The S-adenosylmethionine synthetase type 1 (MAT1A) gene encodes a key enzyme in one-carbon nutrient metabolism...
  20. ncbi request reprint Vitamin B6, B12, and folic acid supplementation and cognitive function: a systematic review of randomized trials
    Ethan M Balk
    Tufts New England Medical Center Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Boston, MA 02111, USA
    Arch Intern Med 167:21-30. 2007
    ....
  21. ncbi request reprint Age and gender affect the relation between methylenetetrahydrofolate reductase C677T genotype and fasting plasma homocysteine concentrations in the Framingham Offspring Study Cohort
    Giuseppina T Russo
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Nutr 133:3416-21. 2003
    ..001). Our results suggest that age and sex modify the contribution of the MTHFR C677T mutation to fasting tHcy concentrations...
  22. ncbi request reprint Folic acid intake from fortification in United States exceeds predictions
    Silvina F Choumenkovitch
    Vitamin Metabolism Laboratory and Nutritional Epidemiology Program, Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Nutr 132:2792-8. 2002
    ..By these estimations, folic acid fortification resulted in a mean increase in folic acid intake that was approximately twice as large as previously projected...
  23. ncbi request reprint Multivitamin use and B vitamin status in a homebound elderly population
    J S Buell
    K L Tucker, USDA HNRCA at Tufts University, 711 Washington Street 9th Floor, Boston, MA 02111, USA
    J Nutr Health Aging 11:299-303. 2007
    ..The purpose of this analysis is to investigate, in a racially diverse group of homebound elders, the association of multivitamin use with measures of plasma B vitamin concentrations...
  24. ncbi request reprint B vitamins, homocysteine, and neurocognitive function in the elderly
    J Selhub
    Jean Mayer US Department of Agriculture Human Nutrition Research Centeron Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 71:614S-620S. 2000
    ....
  25. ncbi request reprint Hyperhomocysteinemia associated with poor recall in the third National Health and Nutrition Examination Survey
    M S Morris
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 73:927-33. 2001
    ..Blood homocysteine concentrations are inversely correlated with performance on some cognitive-function tests and a relation was recently shown between hyperhomocysteinemia and Alzheimer disease...
  26. pmc Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification
    Martha Savaria Morris
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 85:193-200. 2007
    ..This idea is controversial, however, because observational data are few and inconclusive. Furthermore, experimental investigation is unethical...
  27. ncbi request reprint Age-related changes in neutral sphingomyelin-specific phospholipase C activity in striatum, hippocampus, and frontal cortex: implication for sensitivity to stress and inflammation
    Natalia A Crivello
    Nutrition and Neurocognition Laboratory, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Neurochem Int 47:573-9. 2005
    ..1.4.12; N-Sase), a key enzyme of sphingolipid metabolism and sphingolipid-induced signaling...
  28. ncbi request reprint A temporal association between folic acid fortification and an increase in colorectal cancer rates may be illuminating important biological principles: a hypothesis
    Joel B Mason
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Cancer Epidemiol Biomarkers Prev 16:1325-9. 2007
    ..Further work is needed to definitively establish the nature of this relationship. In the meantime, deliberations about the institution or enhancement of fortification programs should be undertaken with these considerations in mind...
  29. ncbi request reprint Public health significance of supplementation or fortification of grain products with folic acid
    Jacob Selhub
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Food Nutr Bull 29:S173-6. 2008
  30. pmc B-vitamin deficiency causes hyperhomocysteinemia and vascular cognitive impairment in mice
    Aron M Troen
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111 1524, USA
    Proc Natl Acad Sci U S A 105:12474-9. 2008
    ..Similar microvascular changes may mediate the association of hyperhomocysteinemia with human age-related cognitive decline...
  31. pmc Folate-vitamin B-12 interaction in relation to cognitive impairment, anemia, and biochemical indicators of vitamin B-12 deficiency
    Jacob Selhub
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 89:702S-6S. 2009
    ....
  32. pmc Aging modifies brain region-specific vulnerability to experimental oxidative stress induced by low dose hydrogen peroxide
    Natalia A Crivello
    Nutrition and Neurocognition Laboratory, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA, 02111, USA
    Age (Dordr) 29:191-203. 2007
    ....
  33. doi request reprint Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors
    Martha Savaria Morris
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 91:1733-44. 2010
    ..However, clinical consequences of vitamin B-12 deficiency may be worsened by high folic acid intakes, perhaps as a direct result of unmetabolized folic acid, which does not occur naturally in body tissues...
  34. doi request reprint B vitamins and the aging brain
    Jacob Selhub
    Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts, USA
    Nutr Rev 68:S112-8. 2010
    ..In light of this, it is imperative to find safe ways of improving vitamin B status in the elderly without exposing some individuals to undue risk...
  35. ncbi request reprint Breakfast cereal fortified with folic acid, vitamin B-6, and vitamin B-12 increases vitamin concentrations and reduces homocysteine concentrations: a randomized trial
    Katherine L Tucker
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Am J Clin Nutr 79:805-11. 2004
    ..High homocysteine and low B vitamin concentrations have been linked to the risk of vascular disease, stroke, and dementia and are relatively common in older adults...
  36. ncbi request reprint Elevated serum methylmalonic acid concentrations are common among elderly Americans
    Martha Savaria Morris
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Nutr 132:2799-803. 2002
    ..We conclude that many elderly Americans demonstrate metabolic evidence of low B-12 status, that elevations occur frequently in the absence of traditional deficiency indicators and that levels vary with race/ethnicity and renal function...
  37. ncbi request reprint Depression and folate status in the US Population
    Martha S Morris
    Jean Mayer United States Department of Agriculture, Human Nutrition Research Center on Aging, Tufts University, Boston, Mass, USA
    Psychother Psychosom 72:80-7. 2003
    ..These relationships have not been demonstrated in general populations. This study examined associations between depression and folate status indicators in an ethnically diverse general US population sample aged 15-39 years...
  38. ncbi request reprint Serum total homocysteine concentrations in children and adolescents: results from the third National Health and Nutrition Examination Survey (NHANES III)
    Aviva Must
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
    J Nutr 133:2643-9. 2003
    ..Improved understanding of the determinants of levels during growth and development may provide important clues to the etiology of adult disease...
  39. ncbi request reprint Hyperhomocysteinemia in renal transplant recipients
    Allon N Friedman
    Vitamin Metabolism and Aging, Tufts Jean Mayer USDA HNRCA, Boston, MA, USA
    Am J Transplant 2:308-13. 2002
    ..For this reason, RTRs have been chosen as an ideal study population in investigating the effect of reducing hyperhomocysteinemia on CVD outcomes...
  40. ncbi request reprint Tropical enteritis: nutritional consequences and connections with the riddle of cholera
    Irwin H Rosenberg
    Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA
    J Nutr 133:333S-335S. 2003
    ....
  41. ncbi request reprint The relationship between riboflavin and plasma total homocysteine in the Framingham Offspring cohort is influenced by folate status and the C677T transition in the methylenetetrahydrofolate reductase gene
    Paul F Jacques
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Nutr 132:283-8. 2002
    ..Our data suggest that riboflavin status may affect homocysteine metabolism, but only in a small segment of the population who have both low folate status and are homozygotes for the MTHFR C677T mutation...
  42. ncbi request reprint Plasma total homocysteine levels among patients undergoing nocturnal versus standard hemodialysis
    Allon N Friedman
    Vitamin Metabolism and Aging, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    J Am Soc Nephrol 13:265-8. 2002
    ..Clinical trials will be necessary to confirm that NHD is effective in reducing tHcy levels among patients with dialysis-dependent end-stage renal disease...
  43. pmc The atherogenic effect of excess methionine intake
    Aron M Troen
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Proc Natl Acad Sci U S A 100:15089-94. 2003
    ..Some product of excess methionine metabolism rather than high plasma homocysteine per se may underlie the association of homocysteine with vascular disease...
  44. pmc Cognitive impairment in folate-deficient rats corresponds to depleted brain phosphatidylcholine and is prevented by dietary methionine without lowering plasma homocysteine
    Aron M Troen
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Nutr 138:2502-9. 2008
    ....
  45. ncbi request reprint Chronic diuretic therapy with moderate doses of triamterene is not associated with folate deficiency
    J B Mason
    Bioavailability Laboratory, USDA Human Nutrition Research Center on Aging, Tufts University, Boston
    J Lab Clin Med 117:365-9. 1991
    ..05). These data suggest that chronic triamterene administration in individuals not living in institutions, at the doses examined in this study, is not associated with indications of folate deficiency...
  46. ncbi request reprint Heterogeneity and lack of good quality studies limit association between folate, vitamins B-6 and B-12, and cognitive function
    Gowri Raman
    Tufts New England Medical Center Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, Boston, MA 02111, USA
    J Nutr 137:1789-94. 2007
    ....
  47. ncbi request reprint Folate and brain function in the elderly
    Kristen E D'Anci
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA
    Curr Opin Clin Nutr Metab Care 7:659-64. 2004
    ..Over the past several decades, folate has emerged as an important nutrient in several key conditions of concern to the elderly. Subclinical levels of folate inadequacy can have significant negative impacts on health in older individuals...
  48. pmc Association of plasma total homocysteine levels with subclinical brain injury: cerebral volumes, white matter hyperintensity, and silent brain infarcts at volumetric magnetic resonance imaging in the Framingham Offspring Study
    Sudha Seshadri
    Department of Neurology, School of Medicine, Boston University, Boston, Massachusetts 02118 2526, USA
    Arch Neurol 65:642-9. 2008
    ..Elevated plasma total homocysteine (tHcy) levels have been associated with increased risk of dementia and stroke, but it is uncertain whether the mediating mechanisms are predominantly cellular, vascular, or both...
  49. pmc A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status
    Simonetta Friso
    Vitamin Metabolism Laboratory, Jean Mayer U S Department of Agriculture Human Nutrition Research on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Proc Natl Acad Sci U S A 99:5606-11. 2002
    ..03) that is known to be solely represented in those individuals. These results indicate that the MTHFR C677T polymorphism influences DNA methylation status through an interaction with folate status...
  50. ncbi request reprint The kidney and homocysteine metabolism
    A N Friedman
    Vitamin Metabolism and Aging, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    J Am Soc Nephrol 12:2181-9. 2001
    ..Efforts to resolve this important issue will advance the search for effective Hcy-lowering therapies in patients with renal disease...
  51. ncbi request reprint Relations of plasma homocysteine to left ventricular structure and function: the Framingham Heart Study
    Johan Sundstrom
    The Framingham Heart Study, Framingham, MA, USA
    Eur Heart J 25:523-30. 2004
    ..Hyperhomocysteinaemia is a risk factor for congestive heart failure, especially in women. We investigated if homocysteine promotes left ventricular (LV) remodelling...
  52. ncbi request reprint Preliminary evidence shows that folic acid fortification of the food supply is associated with higher methotrexate dosing in patients with rheumatoid arthritis
    Senada Arabelovic
    US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
    J Am Coll Nutr 26:453-5. 2007
    ..However, an increase in dietary folate intake could theoretically reduce the effectiveness of the anti-folate medication, methotrexate (MTX) in treating rheumatoid arthritis (RA) and other inflammatory diseases...
  53. ncbi request reprint Fitting nutrition into the medical model: the role of decision analytic cost-effectiveness techniques
    E M Ross
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
    Eur J Clin Nutr 53:S25-8. 1999
    ....
  54. ncbi request reprint The nature of scientific evidence and its relevance to policy
    Irwin H Rosenberg
    Tufts University Human Nutrition Research Center, Boston, Massachusetts 02111, USA
    Forum Nutr 56:184-5. 2003
  55. pmc Vitamin D is associated with cognitive function in elders receiving home health services
    Jennifer S Buell
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
    J Gerontol A Biol Sci Med Sci 64:888-95. 2009
    ..The objective of this study was to examine the association between 25-hydroxyvitamin D, 25(OH)D, and cognitive function...
  56. ncbi request reprint Fish -- food to calm the heart
    Irwin H Rosenberg
    Friedman School of Nutrition Science and Policy at Tufts University, Boston, MA 02111, USA
    N Engl J Med 346:1102-3. 2002
  57. ncbi request reprint Hydration and cognitive function in children
    Kristen E D'Anci
    Nutrition and Neurocognition Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    Nutr Rev 64:457-64. 2006
    ..Dehydration in infants is associated with confusion, irritability, and lethargy; in children, it may produce decrements in cognitive performance...
  58. ncbi request reprint Correspondence: will increasing folic acid in fortified grain products further reduce neural tube defects without causing harm?
    Martha Savaria Morris
    Pediatr Res 63:450; author reply 450-1. 2008
  59. ncbi request reprint Science-based micronutrient fortification: which nutrients, how much, and how to know?
    Irwin H Rosenberg
    Am J Clin Nutr 82:279-80. 2005
  60. ncbi request reprint Plasma homocysteine, hypertension incidence, and blood pressure tracking: the Framingham Heart Study
    Johan Sundstrom
    Framingham Heart Study, Framingham, Mass 01702 5803, USA
    Hypertension 42:1100-5. 2003
    ....
  61. ncbi request reprint Plasma homocysteine as a risk factor for dementia and Alzheimer's disease
    Sudha Seshadri
    Department of Neurology, Boston University School of Medicine, MA 02118 2526, USA
    N Engl J Med 346:476-83. 2002
    ..Studies of newly diagnosed dementia are required in order to establish whether the elevated homocysteine levels precede the onset of dementia or result from dementia-related nutritional and vitamin deficiencies...
  62. ncbi request reprint Plasma homocysteine and risk for congestive heart failure in adults without prior myocardial infarction
    Ramachandran S Vasan
    National Heart, Lung, and Blood Institute s Framingham Heart Study, 73 Mt Wayte Ave, Site 2, Framingham, MA 01702 5803, USA
    JAMA 289:1251-7. 2003
    ..Elevated plasma homocysteine levels are associated with increased risk of vascular disease. It is unclear whether elevated homocysteine levels are a risk factor for congestive heart failure (CHF)...
  63. ncbi request reprint Total homocysteine lowering treatment among coronary artery disease patients in the era of folic acid-fortified cereal grain flour
    Andrew G Bostom
    Division of Renal Diseases, Rhode Island Hospital, Providence 02903, USA
    Arterioscler Thromb Vasc Biol 22:488-91. 2002
    ..These findings have important implications for the statistical power of clinical trials testing the hypothesis that tHcy-lowering treatment may reduce recurrent atherothrombotic event rates...
  64. ncbi request reprint Skeletal muscle cutpoints associated with elevated physical disability risk in older men and women
    Ian Janssen
    Department of Community Health and Epidemiology, Queen s University, Kingston, Ontario, Canada
    Am J Epidemiol 159:413-21. 2004
    ....
  65. ncbi request reprint Agricultural biotechnology: the road to improved nutrition and increased production?
    Kathleen A Merrigan
    Agriculture, Food and Environment Program, Tufts University Friedman School of Nutrition, USA
    Nutr Rev 61:S95-100. 2003
  66. ncbi request reprint Editor's comment. The science and policy feature of this issue
    Irwin H Rosenberg
    Nutr Rev 65:503. 2007
  67. ncbi request reprint Is it time to standardize and to measure blood homocysteine levels in patients with heart disease?
    Irwin H Rosenberg
    Am J Med 112:582-3. 2002
  68. ncbi request reprint Endothelial function in healthy younger and older hyperhomocysteinemic subjects
    Sandra Hirsch
    INTA, Institute of Nutrition and Food Technology, University of Chile, Macul 5540, Casilla 138 11, Santiago, Chile
    J Am Geriatr Soc 50:1019-23. 2002
    ..To compare endothelium-dependent vasomotor response in healthy younger and older subjects without classic cardiovascular risk factors, with high and normal fasting homocysteine (tHcy) levels...
  69. ncbi request reprint Demographics and trends in overweight and obesity in patients at time of kidney transplantation
    Allon N Friedman
    Division of Nephrology, Indiana University School of Medicine, Indianapolis, IN, USA
    Am J Kidney Dis 41:480-7. 2003
    ..The authors describe the prevalence, demographics, and trends in overweight and obesity at the time of kidney transplantation...
  70. ncbi request reprint Child Nutrition Initiative in Israel and Palestine: Status of food security, micronutrient malnutrition, and behavioral change and communication programs
    Aron M Troen
    Ben Gurion University, Beersheba, Israel
    Food Nutr Bull 27:180-5. 2006
  71. ncbi request reprint Trials that matter: should we routinely measure homocysteine levels and "treat" mild hyperhomocysteinemia?
    Irwin H Rosenberg
    Ann Intern Med 145:226-7. 2006
  72. ncbi request reprint Rethinking brain food
    Irwin H Rosenberg
    Am J Clin Nutr 86:1259-60. 2007

Research Grants6

  1. Micronutrients, stroke and cognition in aging
    Irwin Rosenberg; Fiscal Year: 2006
    ..abstract_text> ..
  2. Renal Transplantation, Homocysteine Lowering & Cognition
    Irwin Rosenberg; Fiscal Year: 2007
    ..Demonstrating the cognitive benefits of lowering homocysteine may pave the way to nutritional modification of cognitive decline in RTRs and other high-risk groups and even in the general population. ..