Research Topics
Genomes and GenesSpecies | Ayan R. PatelSummaryAffiliation: Tufts Medical Center Location: Boston, USA Publications
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Publications
The pulmonary artery pulsatility index identifies severe right ventricular dysfunction in acute inferior myocardial infarctionRavi Korabathina
Division of Cardiology, Tufts Medical Center, Boston, Massachusetts 02111, USA
Catheter Cardiovasc Interv 80:593-600. 2012..We defined a novel hemodynamic index, the pulmonary artery pulsatility index (PAPi), and explored whether the PAPi correlates with severe RVD in acute IWMI...
Influence of donor cocaine use on outcome after cardiac transplantation: analysis of the United Network for Organ Sharing Thoracic RegistryAndreas Brieke
Division of Cardiology, University of Colorado at Denver and Health Sciences Center, Aurora, Colorado 80045, USA
J Heart Lung Transplant 27:1350-2. 2008....
Imaging modalities in valvular heart diseaseFrancisco Aguilar
Center for Cardiovascular Imaging, Tufts New England Medical Center, 750 Washington Street, Box 32, Boston, MA 02111, USA
Curr Cardiol Rep 10:98-103. 2008..This array of imaging modalities is likely to provide greater insights into the pathophysiology of valvular heart disease, new pointers to prognosis, and also guide innovative treatment strategies...
Usefulness of tricuspid annular velocity in identifying global RV dysfunction in patients with primary pulmonary hypertension: a comparison with 3D echo-derived right ventricular ejection fractionStefano De Castro
La Sapienza, University of Rome, Rome, Italy
Echocardiography 25:289-93. 2008..5 cm/sec yields significantly high sensitivity and specificity and appears to be a valid compromise in detecting RV dysfunction, TAPSV values however are not useful in evaluating the severity of RV dysfunction...
Has the clinical presentation and clinician's index of suspicion of cardiac tamponade changed over the past decade?Sachin Gandhi
Cardiovascular Imaging and Hemodynamic Laboratory, Division of Cardiology, Tufts New England Medical Center, Boston, MA, USA
Echocardiography 25:237-41. 2008..However, the diagnosis of CT still remains delayed, and the present data emphasize the need for a heightened index of suspicion for recognizing this hemodynamically-important process...
Association of aortic atherosclerosis and renal dysfunctionMilind Y Desai
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio 44195, USA
J Am Soc Echocardiogr 21:751-5. 2008..Both aortic atherosclerosis (AA) and renal dysfunction are associated with increased morbidity and mortality. We sought to assess the association between AA and renal dysfunction...
Treatment of hypercholesterolemia with ezetimibe in cardiac transplant recipientsAyan R Patel
Heart Failure and Cardiac Transplant Center, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
J Heart Lung Transplant 26:281-4. 2007..This initial experience indicates that ezetimibe is well tolerated in cardiac transplant recipients and is effective in reducing total and low-density lipoprotein cholesterol levels...
A 32-year-old woman with arthralgias and severe hypotensionEdgar A Martorell
Tufts Medical Center, Boston, Massachusetts 02111, USA
Arthritis Rheum 59:1670-5. 2008
Low levels of high-density lipoprotein cholesterol are associated with vascular remodeling in cardiac transplant recipientsM S Ambrose
Tufts-New England Medical Center, Boston, Massachusetts 02111, USA
Transplant Proc 38:3016-20. 2006..These findings suggest that suboptimal HDL-C levels may be associated with the development of vascular remodeling and atherosclerosis in this population...
Prevalence and clinical characteristics of right ventricular dysfunction in transient stress cardiomyopathyTimothy P Fitzgibbons
Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts, Medical School, Worcester, MA, USA
Am J Cardiol 104:133-6. 2009....
Three-dimensional echocardiography--state-of-the-artAntonietta Evangelista
Center for Cardiovascular Imaging, Tufts University Medical Center, Boston, MA 02111, USA
Indian Heart J 60:C3-9. 2008
Endothelial function and soluble endoglin in smokers with heart failureKevin S Heffernan
Department of Exercise Science, Human Performance Laboratory, Syracuse University, Syracuse, New York 13244, USA
Clin Cardiol 34:729-33. 2011..We examined vascular endothelial function in chronic smokers and nonsmokers with HF as it relates to this smoker's paradox...
Left ventricular twist mechanics in hypertrophic cardiomyopathy assessed by three-dimensional speckle tracking echocardiographyJose A Urbano Moral
Cardiovascular Imaging and Hemodynamic Laboratory, Tufts Medical Center, Boston Massachusetts, USA
Am J Cardiol 108:1788-95. 2011..Elucidating the characteristics of the wringing motion of the heart might help to broaden the understanding of the hyperdynamic contraction and impaired relaxation observed in these patients...
Pre-operative left atrial mechanical function predicts risk of atrial fibrillation following cardiac surgeryJessica A Haffajee
Cardiovascular Imaging and Hemodynamic Laboratory, Tufts Medical Center, Boston, Massachusetts 02111, USA
JACC Cardiovasc Imaging 4:833-40. 2011....
ACCF/ASE/AHA/ASNC/HFSA/HRS/SCAI/SCCM/SCCT/SCMR 2011 Appropriate Use Criteria for Echocardiography. A Report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, American Society of Echocardiography, American Heart AssociatPamela S Douglas
J Am Coll Cardiol 57:1126-66. 2011
Health-related quality of life in a multicenter randomized controlled comparison of telephonic disease management and automated home monitoring in patients recently hospitalized with heart failure: SPAN-CHF II trialVarda Konstam
Department of Counseling and School Psychology, University of Massachusetts, 2 Avery Street, Boston, MA, USA
J Card Fail 17:151-7. 2011....
Left ventricular remodeling in heart failure: current concepts in clinical significance and assessmentMarvin A Konstam
Cardiovascular Center, Tufts Medical Center and Tufts University School of Medicine, Boston, Massachusetts, USA
JACC Cardiovasc Imaging 4:98-108. 2011....
Pressure-volume relationships in patients with transthyretin (ATTR) cardiac amyloidosis secondary to V122I mutations and wild-type transthyretin: Transthyretin Cardiac Amyloid Study (TRACS)Taslima Bhuiyan
Clinical Cardiovascular Research Laboratory for the Elderly, Columbia University, New York, NY 10034, USA
Circ Heart Fail 4:121-8. 2011..We evaluated pressure-volume (PV) indices at baseline and over time to further characterize abnormal pump function in these subjects...
A multicenter randomized controlled evaluation of automated home monitoring and telephonic disease management in patients recently hospitalized for congestive heart failure: the SPAN-CHF II trialAndrew Weintraub
Division of Cardiology, Tufts Medical Center, Boston, MA, USA
J Card Fail 16:285-92. 2010..The AHM system measured and transmitted body weight, blood pressure, and heart rate data as well as subjective patient self-assessments via a standard telephone line to a central server...
Quantification of right ventricular volumes and function by real time three-dimensional echocardiographic longitudinal axial plane method: validation in the clinical settingYuka Endo
Cardiovascular Imaging and Hemodynamic Laboratory, Division of Cardiology, Tufts-New England Medical Center, Boston, Massachusetts 02111, USA
Echocardiography 23:853-9. 2006..0001 for all comparisons). CONCLUSION: 3DE longitudinal-axis analysis is a promising technique for the evaluation of RV function, and may provide an alternative method of assessment in patients with suboptimal short-axis images...
Quantitation of right ventricular volumes and ejection fraction by three-dimensional echocardiography in patients: comparison with magnetic resonance imaging and radionuclide ventriculographyH Joachim Nesser
Department of Cardiology, Public Hospital Elisabethinen, Linz, Austria
Echocardiography 23:666-80. 2006..The accuracy of transthoracic 3DE was comparable to that of the transesophageal approach. Three-dimensional echocardiography has the potential to be useful in the clinical assessment of RV disorders...
Left ventricular remodelling index (LVRI) in various pathophysiological conditions: a real-time three-dimensional echocardiographic studyStefano De Castro
Department of Cardiovascular, Respiratory and Morphological Sciences, La Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy
Heart 93:205-9. 2007..Various studies have reported a close correlation between real-time three-dimensional echocardiography (RT3DE) and cine magnetic resonance imaging studies for the assessment of cardiac volumes and mass...
Is the mitral valve area flow-dependent in mitral stenosis? A dobutamine stress echocardiographic studyJagdish C Mohan
Department of Cardiology, G B Pant Hospital, New Delhi, India
J Am Coll Cardiol 40:1809-15. 2002....
Randomized, controlled evaluation of short- and long-term benefits of heart failure disease management within a diverse provider network: the SPAN-CHF trialCarey Kimmelstiel
Division of Cardiology, Tufts-New England Medical Center, and Tufts University School of Medicine, Boston, Mass 02111, USA
Circulation 110:1450-5. 2004..Longer-term benefit likely requires more active chronic intervention, even among patients who appear clinically stable...
Recent advances in the treatment of heart failureAyan R Patel
Division of Cardiology, New England Medical Center and Tufts University, Boston, Massachusetts 02111, USA
Circ J 66:117-21. 2002..As the importance of neurohormonal activation in the progression of heart failure becomes increasingly apparent, new therapeutic strategies targeting these neurohormonal systems are being investigated...
Intraoperative transesophageal echocardiography: correlation of echocardiographic findings and surgical pathologyY Mochizuki
Division of Cardiology, Tufts New England Medical Center Hospitals, 750 Washington Street, Boston, MA 02111, USA
Cardiol Rev 7:270-6. 1999..TEE is helpful for the assessment of the immediate result of surgery and detection of complications that may need a prompt response. Thus, intraoperative TEE has a vital impact on management of cardiac surgery...
Heart failure etiology affects peripheral vascular endothelial function after cardiac transplantationA R Patel
Cardiovascular Imaging and Hemodynamic Laboratory, New England Medical Center Hospitals Inc, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
J Am Coll Cardiol 37:195-200. 2001..These findings indicate that cardiac transplantation corrects peripheral endothelial function for patients without ischemic heart disease, but not in those with prior atherosclerotic coronary disease...
Does chronic mitral regurgitation influence Doppler pressure half-time-derived calculation of the mitral valve area in patients with mitral stenosis?Jagdish C Mohan
Division of Cardiology, G B Pant Hospital, New Delhi, India
Am Heart J 148:703-9. 2004..This study was undertaken to assess whether the presence of concomitant mitral regurgitation (MR) affects mitral valve area (MVA) estimation by PHT...
Mitral regurgitation: comprehensive assessment by echocardiographyA R Patel
Cardiovascular Imaging and Hemodynamic Laboratory, New England Medical Center, 750 Washington Street, Box 32, Boston, MA 02111, USA
Echocardiography 17:275-83. 2000..In patients with severe mitral regurgitation, echocardiographic assessment of ventricular size and function plays a critical role in determining the optimal timing of surgery...
Role of noninvasive testing in the clinical evaluation of women with suspected coronary artery disease: Consensus statement from the Cardiac Imaging Committee, Council on Clinical Cardiology, and the Cardiovascular Imaging and Intervention Committee, CounJennifer H Mieres
Circulation 111:682-96. 2005....
Echocardiographic analysis of regional and global left ventricular shape in Chagas' cardiomyopathyA R Patel
Cardiovascular Imaging and Hemodynamic Laboratory, New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA
Am J Cardiol 82:197-202. 1998..15) (apical 2-chamber view). In Chagas' cardiomyopathy, LV apical deformation results in disruption of the optimal global prolate-ellipsoid shape, even in patients with relatively preserved LV volumes...
Right ventricular dilation in primary amyloidosis: an independent predictor of survivalA R Patel
Evans Memorial Department of Clinical Research, Arthritis Research Center, Boston University Medical Center, Massachusetts 02118, USA
Am J Cardiol 80:486-92. 1997..RV dilation in patients with amyloid heart disease appears to be associated with more severe involvement and is associated with a very poor prognosis with a median survival of only 4 months...
Echocardiographic diagnosis of air embolism associated with central venous catheter placement: case report and review of the literaturePrasad Maddukuri
Cardiovascular Imaging and Hemodynamic Laboratory, Division of Cardiology, Tufts-New England Medical Center, Boston, Massachusetts 02111, USA
Echocardiography 23:315-8. 2006..This case report highlights this uncommon but potentially life-threatening complication of central line placement and the utility of echocardiography in its evaluation...
What is the best approach for the assessment of left atrial size? Comparison of various unidimensional and two-dimensional parameters with three-dimensional echocardiographically determined left atrial volumePrasad V Maddukuri
Cardiovascular Imaging and Hemodynamic Laboratory, Division of Cardiology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
J Am Soc Echocardiogr 19:1026-32. 2006..This study examined the accuracy of these 2DE parameters compared to 3-dimensional echocardiographic LA volume (3DV)...
Modestly overweight women have vascular endothelial dysfunctionAyan R Patel
Division of Cardiology, Tufts Medical Center, Boston, Massachusetts, USA
Clin Cardiol 32:269-73. 2009....
Echocardiographic characterization of left ventricular apical hypoplasia accompanied by a patent ductus arteriosusJessica A Haffajee
Cardiovascular Imaging and Hemodynamic Laboratory, Tufts Medical Center, Boston 02111 MA, USA
Eur J Echocardiogr 12:E17. 2011..As more cases are recognized and patients are followed over time, the natural history and optimal treatment for this cardiomyopathy may be further elucidated...
Pulse wave amplitude is associated with brachial artery diameter: implications for gender differences in microvascular functionKevin S Heffernan
Vascular Function Study Group, Department of Medicine, Division of Cardiology, Tufts Medical Center, Boston, MA 02111, USA
Vasc Med 15:39-45. 2010..In conclusion, PWA-RHI obtained from PAT is associated with BAD. Studies examining gender differences in microvascular endothelial function with PAT may need to correct for BAD as a potential confounder...
Assessment of peripheral vascular endothelial function with finger arterial pulse wave amplitudeJeffrey T Kuvin
Department of Medicine, Division of Cardiology, Tufts New England Medical Center Hospitals, Tufts University School of Medicine, Boston, MA 02111, USA
Am Heart J 146:168-74. 2003..We evaluated the relationship between changes in PWA of the finger and peripheral endothelial function...
Peripheral vascular endothelial function correlates with exercise capacity in cardiac transplant recipientsAyan R Patel
Division of Cardiology/Department of Medicine, Molecular Cardiology Research Institute, Tufts-New England Medical Center, Boston, Massachusetts 02111, USA
Am J Cardiol 91:897-9. 2003
Relation between high-density lipoprotein cholesterol and peripheral vasomotor functionJeffrey T Kuvin
Department of Medicine Division of Cardiology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
Am J Cardiol 92:275-9. 2003..These data suggest that impaired endothelial function associated with low HDL cholesterol may be an additional, previously unrecognized mechanism contributing to the increased risk of atherosclerosis in these patients...
Peripheral vascular endothelial function in patients with hypertrophic cardiomyopathyKevin S Heffernan
The Vascular Function Study Group, The Hypertrophic Cardiomyopathy Center, Tufts Medical Center, Boston, Massachusetts, USA
Am J Cardiol 105:112-5. 2010..Patients with HC have impaired peripheral conduit vessel endothelial function, and the magnitude of impairment is similar to that seen in older patients with advanced CAD...
Comparison of flow-mediated dilatation of the brachial artery in coronary patients with low-density lipoprotein cholesterol levels <80 mg/dl versus patients with levels 80 to 100 mg/dlJeffrey T Kuvin
Division of Cardiology, Department of Medicine, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
Am J Cardiol 95:93-5. 2005..These data support recent reports that decreasing levels of LDL cholesterol below those currently recommended provides additional benefits and suggest that this benefit may be due in part to increased endothelial function...
Gender-based differences in brachial artery flow-mediated vasodilation as an indicator of significant coronary artery diseaseAyan R Patel
The Division of Cardiology, Department of Medicine, Tufts New England Medical Center, Boston, Massachusetts, USA
Am J Cardiol 96:1223-6. 2005..In studies using FMD to evaluate cardiovascular risk, different standards should be applied for women and men...
Peripheral vascular endothelial function correlates with exercise capacity in womenAyan R Patel
Division of Cardiology, Department of Medicine, Tufts New England Medical Center, Boston, MA 02111, USA
Clin Cardiol 28:433-6. 2005..These observations raise the possibility that the relationship between endothelial function and exercise capacity in women may differ from that in men...
A novel mechanism for the beneficial vascular effects of high-density lipoprotein cholesterol: enhanced vasorelaxation and increased endothelial nitric oxide synthase expressionJeffrey T Kuvin
Department of Medicine, New England Medical Center Hospitals, Inc, Tufts University School of Medicine, Boston, Mass, USA
Am Heart J 144:165-72. 2002....
3D echocardiography to evaluate right atrial pressure in acutely decompensated heart failure correlation with invasive hemodynamicsAyan R Patel
Cardiovascular Imaging and Hemodynamic Laboratory, Tufts Medical Center, Boston, Massachusetts 02111, USA
JACC Cardiovasc Imaging 4:938-45. 2011....
Vascular endothelial dysfunction is associated with reversible myocardial perfusion defects in the absence of obstructive coronary artery diseasePrem Soman
Division of Cardiology, Tufts New England Medical Center, Boston, Mass, USA
J Nucl Cardiol 13:756-60. 2006..Recent evidence suggests that coronary endothelial dysfunction might play a role in the pathogenesis of these defects...
Effect of short-term antibiotic treatment on Chlamydia pneumoniae and peripheral endothelial functionJeffrey T Kuvin
Division of Cardiology, Department of Medicine, Tufts-New England Medical Center, Boston, Massachusetts, USA
Am J Cardiol 91:732-5. 2003
