Martha Savaria Morris

Summary

Affiliation: Tufts University
Country: USA

Publications

  1. pmc The role of B vitamins in preventing and treating cognitive impairment and decline
    Martha Savaria Morris
    Nutritional Epidemiology Program, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    Adv Nutr 3:801-12. 2012
  2. pmc Vitamin B-12 and folate status in relation to decline in scores on the mini-mental state examination in the framingham heart study
    Martha Savaria Morris
    Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    J Am Geriatr Soc 60:1457-64. 2012
  3. doi Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors
    Martha Savaria Morris
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 91:1733-44. 2010
  4. pmc Vitamin B-6 intake is inversely related to, and the requirement is affected by, inflammation status
    Martha Savaria Morris
    Nutritional Epidemiology Program, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Nutr 140:103-10. 2010
  5. ncbi Plasma pyridoxal 5'-phosphate in the US population: the National Health and Nutrition Examination Survey, 2003-2004
    Martha Savaria Morris
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 87:1446-54. 2008
  6. ncbi Intake of zinc and antioxidant micronutrients and early age-related maculopathy lesions
    Martha Savaria Morris
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
    Ophthalmic Epidemiol 14:288-98. 2007
  7. ncbi The association between serum thyroid-stimulating hormone in its reference range and bone status in postmenopausal American women
    Martha Savaria Morris
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington St, Room 901D, Boston, MA 02111, USA
    Bone 40:1128-34. 2007
  8. pmc Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification
    Martha Savaria Morris
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 85:193-200. 2007
  9. ncbi Relation between homocysteine and B-vitamin status indicators and bone mineral density in older Americans
    Martha Savaria Morris
    Nutritional Epidemiology Program, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University Boston, Tufts JM USDA HNRCA, 711 Washington Street, Room 901D, Boston, MA 02111, USA
    Bone 37:234-42. 2005
  10. ncbi Elevated serum methylmalonic acid concentrations are common among elderly Americans
    Martha Savaria Morris
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Nutr 132:2799-803. 2002

Research Grants

  1. Vitamin B12 Status of Elderly Americans
    MARTHA MORRIS; Fiscal Year: 2003

Detail Information

Publications19

  1. pmc The role of B vitamins in preventing and treating cognitive impairment and decline
    Martha Savaria Morris
    Nutritional Epidemiology Program, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    Adv Nutr 3:801-12. 2012
    ..Although consistency of findings across studies is often touted as essential to distinguishing causal from coincidental relationships, discrepancies among study findings can be even more informative...
  2. pmc Vitamin B-12 and folate status in relation to decline in scores on the mini-mental state examination in the framingham heart study
    Martha Savaria Morris
    Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    J Am Geriatr Soc 60:1457-64. 2012
    ..To investigate the cognitive significance of low to low-normal plasma vitamin B-12 concentrations and to shed light on the role that folate status plays in the association between vitamin B-12 status and cognitive decline...
  3. doi Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors
    Martha Savaria Morris
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 91:1733-44. 2010
    ..However, clinical consequences of vitamin B-12 deficiency may be worsened by high folic acid intakes, perhaps as a direct result of unmetabolized folic acid, which does not occur naturally in body tissues...
  4. pmc Vitamin B-6 intake is inversely related to, and the requirement is affected by, inflammation status
    Martha Savaria Morris
    Nutritional Epidemiology Program, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Nutr 140:103-10. 2010
    ....
  5. ncbi Plasma pyridoxal 5'-phosphate in the US population: the National Health and Nutrition Examination Survey, 2003-2004
    Martha Savaria Morris
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 87:1446-54. 2008
    ....
  6. ncbi Intake of zinc and antioxidant micronutrients and early age-related maculopathy lesions
    Martha Savaria Morris
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
    Ophthalmic Epidemiol 14:288-98. 2007
    ..Results of observational and intervention studies have been inconsistent...
  7. ncbi The association between serum thyroid-stimulating hormone in its reference range and bone status in postmenopausal American women
    Martha Savaria Morris
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington St, Room 901D, Boston, MA 02111, USA
    Bone 40:1128-34. 2007
    ..88-0.99). These results may reflect the existence of clinically significant thyroid hyperfunction in women with serum TSH in the reference range. Alternatively, TSH itself may play a role in the preservation of bone after menopause...
  8. pmc Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification
    Martha Savaria Morris
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 85:193-200. 2007
    ..This idea is controversial, however, because observational data are few and inconclusive. Furthermore, experimental investigation is unethical...
  9. ncbi Relation between homocysteine and B-vitamin status indicators and bone mineral density in older Americans
    Martha Savaria Morris
    Nutritional Epidemiology Program, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University Boston, Tufts JM USDA HNRCA, 711 Washington Street, Room 901D, Boston, MA 02111, USA
    Bone 37:234-42. 2005
    ..Whether this association reflects a causal relation remains unclear and merits further study in light of age-related declines in B12 status and BMD, and the need for low-risk, easily implemented strategies for osteoporosis prevention...
  10. ncbi Elevated serum methylmalonic acid concentrations are common among elderly Americans
    Martha Savaria Morris
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Nutr 132:2799-803. 2002
    ..We conclude that many elderly Americans demonstrate metabolic evidence of low B-12 status, that elevations occur frequently in the absence of traditional deficiency indicators and that levels vary with race/ethnicity and renal function...
  11. ncbi Homocysteine and Alzheimer's disease
    Martha Savaria Morris
    Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Lancet Neurol 2:425-8. 2003
    ..Future research should focus on early detection of AD and on the possibility that the disease itself, or its primary symptom, could be prevented by folate supplementation...
  12. pmc Folate-vitamin B-12 interaction in relation to cognitive impairment, anemia, and biochemical indicators of vitamin B-12 deficiency
    Jacob Selhub
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 89:702S-6S. 2009
    ....
  13. pmc In vitamin B12 deficiency, higher serum folate is associated with increased total homocysteine and methylmalonic acid concentrations
    Jacob Selhub
    Vitamin Metabolism Laboratory and Nutritional Epidemiology Program, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Proc Natl Acad Sci U S A 104:19995-20000. 2007
    ..These results suggest a worsening of vitamin B(12)'s enzymatic functions as folate status increases in people who are vitamin B(12)-deficient...
  14. ncbi Moderate alcoholic beverage intake and early nuclear and cortical lens opacities
    Martha Savaria Morris
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Channing Laboratory, Harvard School of Public Health, Boston, MA 02111, USA
    Ophthalmic Epidemiol 11:53-65. 2004
    ..To study the relationship between alcoholic beverage intake and early lens opacities...
  15. ncbi Folate, homocysteine, and neurological function
    Martha Savaria Morris
    Nutritional Epidemiology Program, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, 9th Floor, Boston, MA 02111, USA
    Nutr Clin Care 5:124-32. 2002
    ....
  16. ncbi Depression and folate status in the US Population
    Martha S Morris
    Jean Mayer United States Department of Agriculture, Human Nutrition Research Center on Aging, Tufts University, Boston, Mass, USA
    Psychother Psychosom 72:80-7. 2003
    ..These relationships have not been demonstrated in general populations. This study examined associations between depression and folate status indicators in an ethnically diverse general US population sample aged 15-39 years...
  17. doi Total protein, animal protein and physical activity in relation to muscle mass in middle-aged and older Americans
    Martha Savaria Morris
    Nutritional Epidemiology Program, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Room 901D, Boston, MA 02111, USA
    Br J Nutr 109:1294-303. 2013
    ..The present findings reinforce the idea that muscle-strengthening exercise preserves muscle when combined with adequate dietary protein. Vigorous aerobic activity may also help...
  18. ncbi Carbohydrate intake and glycemic index in relation to the odds of early cortical and nuclear lens opacities
    Chung Jung Chiu
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 81:1411-6. 2005
    ..Animal studies suggest a role for dietary carbohydrate in cataractogenesis. However, few published human studies have evaluated associations between carbohydrate nutrition and lens opacification...
  19. ncbi Correspondence: will increasing folic acid in fortified grain products further reduce neural tube defects without causing harm?
    Martha Savaria Morris
    Pediatr Res 63:450; author reply 450-1. 2008

Research Grants1

  1. Vitamin B12 Status of Elderly Americans
    MARTHA MORRIS; Fiscal Year: 2003
    ..The third aim is to evaluate the usefulness of a serum vitamin B12 cut-off point of 258 pmol/L, either as the sole indicator of vitamin B12 deficiency in the elderly, or in conjunction with anemia or an elevated metabolite level. ..