Nicola M McKeown

Summary

Affiliation: Tufts University
Country: USA

Publications

  1. doi request reprint Higher magnesium intake reduces risk of impaired glucose and insulin metabolism and progression from prediabetes to diabetes in middle-aged americans
    Adela Hruby
    Corresponding author Nicola M McKeown
    Diabetes Care 37:419-27. 2014
  2. pmc Whole-grain intake and cereal fiber are associated with lower abdominal adiposity in older adults
    Nicola M McKeown
    Nutritional Epidemiology Program, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Nutr 139:1950-5. 2009
  3. pmc Whole- and refined-grain intakes are differentially associated with abdominal visceral and subcutaneous adiposity in healthy adults: the Framingham Heart Study
    Nicola M McKeown
    Nutritional Epidemiology Program, US Department of Agriculture, Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 92:1165-71. 2010
  4. ncbi request reprint Dietary carbohydrates and cardiovascular disease risk factors in the Framingham offspring cohort
    Nicola M McKeown
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street Boston, MA 02111, USA
    J Am Coll Nutr 28:150-8. 2009
  5. doi request reprint Dietary magnesium intake is related to metabolic syndrome in older Americans
    Nicola M McKeown
    Nutritional Epidemiology Department, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Eur J Nutr 47:210-6. 2008
  6. ncbi request reprint Carbohydrate nutrition, insulin resistance, and the prevalence of the metabolic syndrome in the Framingham Offspring Cohort
    Nicola M McKeown
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    Diabetes Care 27:538-46. 2004
  7. pmc Predicted 25-hydroxyvitamin D score and incident type 2 diabetes in the Framingham Offspring Study
    Enju Liu
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 91:1627-33. 2010
  8. pmc Carbohydrate nutrition differs by diabetes status and is associated with dyslipidemia in Boston Puerto Rican adults without diabetes
    Maria I Van Rompay
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
    J Nutr 143:182-8. 2013
  9. ncbi request reprint Magnesium intake is related to improved insulin homeostasis in the framingham offspring cohort
    Marcella E Rumawas
    Nutritional Epidemiology Program, JM USDA HNRC at Tufts University, Boston, MA 02111 1524, USA
    J Am Coll Nutr 25:486-92. 2006
  10. pmc Plasma alkylresorcinols, biomarkers of whole-grain intake, are related to lower BMI in older adults
    Jiantao Ma
    Nutrition Epidemiology Program, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Nutr 142:1859-64. 2012

Detail Information

Publications28

  1. doi request reprint Higher magnesium intake reduces risk of impaired glucose and insulin metabolism and progression from prediabetes to diabetes in middle-aged americans
    Adela Hruby
    Corresponding author Nicola M McKeown
    Diabetes Care 37:419-27. 2014
    ..To assess 7-year associations between magnesium intake and incident prediabetes and/or insulin resistance (IR), and progression from these states to type 2 diabetes...
  2. pmc Whole-grain intake and cereal fiber are associated with lower abdominal adiposity in older adults
    Nicola M McKeown
    Nutritional Epidemiology Program, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Nutr 139:1950-5. 2009
    ..Higher intakes of cereal fiber, particularly from whole-grain sources, are associated with lower total percent body fat and percent trunk fat mass in older adults...
  3. pmc Whole- and refined-grain intakes are differentially associated with abdominal visceral and subcutaneous adiposity in healthy adults: the Framingham Heart Study
    Nicola M McKeown
    Nutritional Epidemiology Program, US Department of Agriculture, Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 92:1165-71. 2010
    ..Observational studies have linked higher intakes of whole grains to lower abdominal adiposity; however, the association between whole- and refined-grain intake and body fat compartments has yet to be reported...
  4. ncbi request reprint Dietary carbohydrates and cardiovascular disease risk factors in the Framingham offspring cohort
    Nicola M McKeown
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street Boston, MA 02111, USA
    J Am Coll Nutr 28:150-8. 2009
    ..The aim of this study was to examine the relationship between carbohydrate intake and dietary glycemic index and several cardiovascular disease risk factors...
  5. doi request reprint Dietary magnesium intake is related to metabolic syndrome in older Americans
    Nicola M McKeown
    Nutritional Epidemiology Department, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Eur J Nutr 47:210-6. 2008
    ..Magnesium (Mg) is an essential cofactor for enzymes involved in glucose and insulin metabolism. Low intakes of dietary magnesium may be linked to greater risk of metabolic syndrome (MS) in older adults...
  6. ncbi request reprint Carbohydrate nutrition, insulin resistance, and the prevalence of the metabolic syndrome in the Framingham Offspring Cohort
    Nicola M McKeown
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    Diabetes Care 27:538-46. 2004
    ..The aim of this study was to examine the relation between carbohydrate-related dietary factors, insulin resistance, and the prevalence of the metabolic syndrome in the Framingham Offspring Cohort...
  7. pmc Predicted 25-hydroxyvitamin D score and incident type 2 diabetes in the Framingham Offspring Study
    Enju Liu
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 91:1627-33. 2010
    ..Accumulating evidence suggests that vitamin D is involved in the development of type 2 diabetes (T2D)...
  8. pmc Carbohydrate nutrition differs by diabetes status and is associated with dyslipidemia in Boston Puerto Rican adults without diabetes
    Maria I Van Rompay
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
    J Nutr 143:182-8. 2013
    ..Longitudinal research on carbohydrate nutrition in relation to diabetes risk factors and blood lipids in Puerto Ricans is warranted...
  9. ncbi request reprint Magnesium intake is related to improved insulin homeostasis in the framingham offspring cohort
    Marcella E Rumawas
    Nutritional Epidemiology Program, JM USDA HNRC at Tufts University, Boston, MA 02111 1524, USA
    J Am Coll Nutr 25:486-92. 2006
    ..Higher dietary intake of magnesium may protect against development of type 2 diabetes. The aim of this study was to examine the association between dietary magnesium intake and metabolic risk factors for diabetes...
  10. pmc Plasma alkylresorcinols, biomarkers of whole-grain intake, are related to lower BMI in older adults
    Jiantao Ma
    Nutrition Epidemiology Program, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Nutr 142:1859-64. 2012
    ....
  11. pmc Acculturation and sociocultural influences on dietary intake and health status among Puerto Rican adults in Massachusetts
    Maria I Van Rompay
    Gerald J and Dorothy R Friedman School of Nutrition Science and Policy, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
    J Acad Nutr Diet 112:64-74. 2012
    ..Despite prevalent type 2 diabetes and low socioeconomic status (SES) among Puerto Rican adults living on the US mainland, little is known about acculturation in this group...
  12. pmc Plasma 25-hydroxyvitamin d is associated with markers of the insulin resistant phenotype in nondiabetic adults
    Enju Liu
    Jean Mayer USDA Human Nutrition Research Center on Aging, Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA
    J Nutr 139:329-34. 2009
    ..Among adults without diabetes, vitamin D status was inversely associated with surrogate fasting measures of insulin resistance. These results suggest that vitamin D status may be an important determinant for type 2 diabetes mellitus...
  13. ncbi request reprint Whole-grain intake is favorably associated with metabolic risk factors for type 2 diabetes and cardiovascular disease in the Framingham Offspring Study
    Nicola M McKeown
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 76:390-8. 2002
    ..The influence of whole grains on cardiovascular disease risk may be mediated through multiple pathways, eg, a reduction in blood lipids and blood pressure, an enhancement of insulin sensitivity, and an improvement in blood glucose control...
  14. pmc Cross-sectional association of dietary patterns with insulin-resistant phenotypes among adults without diabetes in the Framingham Offspring Study
    Enju Liu
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
    Br J Nutr 102:576-83. 2009
    ....
  15. ncbi request reprint Surrogate markers of insulin resistance are associated with consumption of sugar-sweetened drinks and fruit juice in middle and older-aged adults
    Makiko Yoshida
    Nutritional Epidemiology Program, Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Nutr 137:2121-7. 2007
    ..Studies of long-term beverage consumption using more direct measures of insulin sensitivity are clearly warranted...
  16. doi request reprint Whole grain consumption is inversely associated with BMI Z-score in rural school-aged children
    Silvina F Choumenkovitch
    John Hancock Research Center on Physical Activity, Nutrition, and Obesity Prevention, Friedman School of Nutrition Science and Policy, Tufts University, 150 Harrison Avenue, Boston, MA 02111, USA
    Public Health Nutr 16:212-8. 2013
    ..To examine the relationship between intake of whole grains and BMI Z-score in rural children...
  17. pmc The development of the Mediterranean-style dietary pattern score and its application to the American diet in the Framingham Offspring Cohort
    Marcella E Rumawas
    Nutritional Epidemiology, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Nutr 139:1150-6. 2009
    ..The MSDPS is a useful instrument to measure overall diet quality according to the principles of a Mediterranean-style dietary pattern...
  18. pmc Mediterranean-style dietary pattern, reduced risk of metabolic syndrome traits, and incidence in the Framingham Offspring Cohort
    Marcella E Rumawas
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111 1524, USA
    Am J Clin Nutr 90:1608-14. 2009
    ..The benefit of the Mediterranean-style dietary pattern in mitigating metabolic risk factors for type 2 diabetes and cardiovascular disease has not been well investigated among nondiabetic Americans...
  19. ncbi request reprint Dietary and nondietary determinants of vitamin K biochemical measures in men and women
    Nicola M McKeown
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Nutr 132:1329-34. 2002
    ..Despite these caveats, these findings support the use of a FFQ for a relative assessment of vitamin K status in population-based studies...
  20. doi request reprint Magnesium intake is inversely associated with coronary artery calcification: the Framingham Heart Study
    Adela Hruby
    Nutritional Epidemiology Program, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts
    JACC Cardiovasc Imaging 7:59-69. 2014
    ..The aim of this study was to examine whether magnesium intake is associated with coronary artery calcification (CAC) and abdominal aortic calcification (AAC)...
  21. ncbi request reprint Whole grain intake and insulin sensitivity: evidence from observational studies
    Nicola M McKeown
    Nutritional Epidemiology Program, Jean Mayer USDA Human Nutrition Research Center, Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Nutr Rev 62:286-91. 2004
    ..The improved insulin sensitivity may be mediated in part by magnesium and dietary fiber, two nutrients found in whole-grain foods. By incorporating whole-grain foods into the diet, therefore, insulin sensitivity might be improved...
  22. ncbi request reprint Sugar-sweetened beverages and prevalence of the metabolically abnormal phenotype in the Framingham Heart Study
    Angela K Green
    Tufts University Medical School, Boston, Massachusetts, USA
    Obesity (Silver Spring) 22:E157-63. 2014
    ..The purpose of this study was to examine the relationship between usual sugar-sweetened beverage (SSB) consumption and prevalence of abnormal metabolic health across body mass index (BMI) categories...
  23. pmc Higher magnesium intake is associated with lower fasting glucose and insulin, with no evidence of interaction with select genetic loci, in a meta-analysis of 15 CHARGE Consortium Studies
    Adela Hruby
    Tufts University Friedman School of Nutrition Science and Policy, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Nutr 143:345-53. 2013
    ..Nominal evidence of TRPM6 influence and magnesium interaction with select loci suggests that further investigation is warranted...
  24. doi request reprint Whole grains and health: from theory to practice--highlights of The Grains for Health Foundation's Whole Grains Summit 2012
    Nicola M McKeown
    Nutritional Epidemiology Program, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
    J Nutr 143:744S-758S. 2013
    ..A prerequisite of that is the need to build trust among diverse multidisciplinary professionals involved in the growing, producing, marketing, and regulating of whole-grain products and between the grain and public health communities...
  25. doi request reprint Prevalence of cardiovascular disease risk factors among older Puerto Rican adults living in Massachusetts
    Maria I Van Rompay
    Nutrition and Genomics Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
    J Immigr Minor Health 13:825-33. 2011
    ..Puerto Rican adults living in the Boston area showed several metabolic abnormalities and high CVD risk, likely due to pervasive obesity and socio-economic disparities...
  26. pmc Dietary magnesium and genetic interactions in diabetes and related risk factors: a brief overview of current knowledge
    Adela Hruby
    Department of Nutrition, Harvard School of Public Health, 677 Huntington Avenue, Building 2, Boston, MA 02115, USA
    Nutrients 5:4990-5011. 2013
    ..This brief review summarizes the recent evidence on dietary magnesium's role in diabetes and related traits in the presence of underlying genetic risk, and discusses future potential research directions. ..
  27. doi request reprint Hepatic biotransformation of alkylresorcinols is mediated via cytochrome P450 and β-oxidation: a proof of concept study
    Matti Marklund
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Food Chem 139:925-30. 2013
    ..Our results are consistent with a metabolic pathway by which AR are degraded to phenolic acids via CYP4F2-mediated ω-oxidation and subsequent β-oxidation...
  28. ncbi request reprint Whole-grain intake is inversely associated with the metabolic syndrome and mortality in older adults
    Nadine R Sahyoun
    Department of Nutrition and Food Science, University of Maryland, College Park, MD 20742, USA
    Am J Clin Nutr 83:124-31. 2006
    ..The metabolic consequence of consuming high whole-grain diets may differ in elderly persons, who are prone to greater insulin resistance and impaired glucose tolerance...