Timothy E McAlindon

Summary

Affiliation: Tufts Medical Center
Country: USA

Publications

  1. doi request reprint Change in knee osteoarthritis cartilage detected by delayed gadolinium enhanced magnetic resonance imaging following treatment with collagen hydrolysate: a pilot randomized controlled trial
    T E McAlindon
    Division of Rheumatology, Tufts Medical Center, Box 406, 800 Washington Street, Boston, MA 02111, USA
    Osteoarthritis Cartilage 19:399-405. 2011
  2. ncbi request reprint Development of a rapid knee cartilage damage quantification method using magnetic resonance images
    Ming Zhang
    Division of Rheumatology, Tufts Medical Center, 800 Washington Street, Box 406, Boston, MA 02111, USA
    BMC Musculoskelet Disord 15:264. 2014
  3. ncbi request reprint OARSI guidelines for the non-surgical management of knee osteoarthritis
    T E McAlindon
    Division of Rheumatology, Tufts Medical Center, Boston, MA, USA Electronic address
    Osteoarthritis Cartilage 22:363-88. 2014
  4. pmc Individual patient data meta-analysis of trials investigating the effectiveness of intra-articular glucocorticoid injections in patients with knee or hip osteoarthritis: an OA Trial Bank protocol for a systematic review
    Marienke van Middelkoop
    Department of General Practice, Erasmus MC Medical University, PO Box 2040, 3000, CA, Rotterdam, The Netherlands
    Syst Rev 2:54. 2013
  5. pmc Physiological effects of oral glucosamine on joint health: current status and consensus on future research priorities
    Yves Henrotin
    Bone and Cartilage Research Unit, University of Liege, Institute of Pathology, Level 5, CHU Sart Tilman, Liege, 4000, Belgium
    BMC Res Notes 6:115. 2013
  6. pmc Quantification of bone marrow lesion volume and volume change using semi-automated segmentation: data from the osteoarthritis initiative
    Jincheng Pang
    Department of Electrical and Computer Engineering, Tufts University, 216 Halligan Hall, Medford, MA 02155, USA
    BMC Musculoskelet Disord 14:3. 2013
  7. pmc Racial differences in symptom management approaches among persons with radiographic knee osteoarthritis
    Shibing Yang
    Department of Epidemiology and Community Health, Virginia Commonwealth University, Richmond, USA
    BMC Complement Altern Med 12:86. 2012
  8. pmc Effect of vitamin D supplementation on progression of knee pain and cartilage volume loss in patients with symptomatic osteoarthritis: a randomized controlled trial
    Timothy McAlindon
    Division of Rheumatology, Tufts Medical Center, Box 406, 800 Washington St, Boston, MA 02111, USA
    JAMA 309:155-62. 2013
  9. doi request reprint Osteoarthritis year 2011 in review: clinical
    T E McAlindon
    Division of Rheumatology, Tufts Medical Center, Boston, MA 02111, USA
    Osteoarthritis Cartilage 20:197-200. 2012
  10. pmc Phase 1 safety and tolerability study of BMP-7 in symptomatic knee osteoarthritis
    David J Hunter
    Division of Research, New England Baptist Hospital, 125 Parker Hill Ave, Boston, MA 02120, US
    BMC Musculoskelet Disord 11:232. 2010

Research Grants

  1. Trial of Vitamin D to Reduce Progression of Knee OA
    Timothy McAlindon; Fiscal Year: 2007
  2. FEASIBILITY OF INTERNET-BASED TRIALS FOR OSTEOARTHRITIS
    Timothy McAlindon; Fiscal Year: 2000
  3. FEASIBILITY OF INTERNET-BASED TRIALS FOR OSTEOARTHRITIS
    Timothy McAlindon; Fiscal Year: 2001
  4. Trial of Vitamin D to Reduce Progression of Knee OA
    Timothy McAlindon; Fiscal Year: 2005
  5. The Role of Bone in Osteoarthritis Progression
    Timothy McAlindon; Fiscal Year: 2009
  6. The Role of Bone in Osteoarthritis Progression
    Timothy E McAlindon; Fiscal Year: 2010
  7. FEASIBILITY OF INTERNET-BASED TRIALS FOR OSTEOARTHRITIS
    Timothy McAlindon; Fiscal Year: 1999
  8. Trial of Vitamin D to Reduce Progression of Knee OA
    Timothy McAlindon; Fiscal Year: 2006
  9. FEASIBILITY OF INTERNET-BASED TRIALS FOR OSTEOARTHRITIS
    Timothy McAlindon; Fiscal Year: 2000
  10. Effect of Intra-Articular Steroids on Structural Progression of Knee OA: An RCT
    Timothy E McAlindon; Fiscal Year: 2010

Collaborators

Detail Information

Publications23

  1. doi request reprint Change in knee osteoarthritis cartilage detected by delayed gadolinium enhanced magnetic resonance imaging following treatment with collagen hydrolysate: a pilot randomized controlled trial
    T E McAlindon
    Division of Rheumatology, Tufts Medical Center, Box 406, 800 Washington Street, Boston, MA 02111, USA
    Osteoarthritis Cartilage 19:399-405. 2011
    ....
  2. ncbi request reprint Development of a rapid knee cartilage damage quantification method using magnetic resonance images
    Ming Zhang
    Division of Rheumatology, Tufts Medical Center, 800 Washington Street, Box 406, Boston, MA 02111, USA
    BMC Musculoskelet Disord 15:264. 2014
    ..In this study we tested the feasibility, reliability, and construct validity of a novel osteoarthritis cartilage damage quantification method (Cartilage Damage Index [CDI]) that utilizes informative locations on knee MRIs...
  3. ncbi request reprint OARSI guidelines for the non-surgical management of knee osteoarthritis
    T E McAlindon
    Division of Rheumatology, Tufts Medical Center, Boston, MA, USA Electronic address
    Osteoarthritis Cartilage 22:363-88. 2014
    ..To develop concise, up-to-date, patient-focused, evidence-based, expert consensus guidelines for the management of knee osteoarthritis (OA), intended to inform patients, physicians, and allied healthcare professionals worldwide...
  4. pmc Individual patient data meta-analysis of trials investigating the effectiveness of intra-articular glucocorticoid injections in patients with knee or hip osteoarthritis: an OA Trial Bank protocol for a systematic review
    Marienke van Middelkoop
    Department of General Practice, Erasmus MC Medical University, PO Box 2040, 3000, CA, Rotterdam, The Netherlands
    Syst Rev 2:54. 2013
    ....
  5. pmc Physiological effects of oral glucosamine on joint health: current status and consensus on future research priorities
    Yves Henrotin
    Bone and Cartilage Research Unit, University of Liege, Institute of Pathology, Level 5, CHU Sart Tilman, Liege, 4000, Belgium
    BMC Res Notes 6:115. 2013
    ..This paper summarizes the available evidence for beneficial effects of GlcN on joint health and proposes new insight into the design of future clinical trials aimed at identifying beneficial physiological effect of GlcN on joint tissues...
  6. pmc Quantification of bone marrow lesion volume and volume change using semi-automated segmentation: data from the osteoarthritis initiative
    Jincheng Pang
    Department of Electrical and Computer Engineering, Tufts University, 216 Halligan Hall, Medford, MA 02155, USA
    BMC Musculoskelet Disord 14:3. 2013
    ..To determine the validity of a semi-automated segmentation of bone marrow lesions (BMLs) in the knee...
  7. pmc Racial differences in symptom management approaches among persons with radiographic knee osteoarthritis
    Shibing Yang
    Department of Epidemiology and Community Health, Virginia Commonwealth University, Richmond, USA
    BMC Complement Altern Med 12:86. 2012
    ..The purpose of this study was to describe the differences between African Americans (AA) and Caucasian Americans (CA) in using treatment approaches to manage symptoms among individuals with radiographic-confirmed knee OA...
  8. pmc Effect of vitamin D supplementation on progression of knee pain and cartilage volume loss in patients with symptomatic osteoarthritis: a randomized controlled trial
    Timothy McAlindon
    Division of Rheumatology, Tufts Medical Center, Box 406, 800 Washington St, Boston, MA 02111, USA
    JAMA 309:155-62. 2013
    ..Knee osteoarthritis (OA), a disorder of cartilage and periarticular bone, is a public health problem without effective medical treatments. Some studies have suggested that vitamin D may protect against structural progression...
  9. doi request reprint Osteoarthritis year 2011 in review: clinical
    T E McAlindon
    Division of Rheumatology, Tufts Medical Center, Boston, MA 02111, USA
    Osteoarthritis Cartilage 20:197-200. 2012
    ..In addition to chondroitin sulfate there were interesting preliminary findings that meniscal implants and joint distractions may modify OA progression...
  10. pmc Phase 1 safety and tolerability study of BMP-7 in symptomatic knee osteoarthritis
    David J Hunter
    Division of Research, New England Baptist Hospital, 125 Parker Hill Ave, Boston, MA 02120, US
    BMC Musculoskelet Disord 11:232. 2010
    ..The secondary objectives were to determine the effect on symptomatic responses through 24 weeks...
  11. pmc Tai Chi for treating knee osteoarthritis: designing a long-term follow up randomized controlled trial
    Chenchen Wang
    Division of Rheumatology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA
    BMC Musculoskelet Disord 9:108. 2008
    ..The study will be completed by July 2009...
  12. pmc Quantitative bone marrow lesion size in osteoarthritic knees correlates with cartilage damage and predicts longitudinal cartilage loss
    Jeffrey B Driban
    Division of Rheumatology, Tufts Medical Center, 800 Washington Street, Box 406, Boston, MA 02111, USA
    BMC Musculoskelet Disord 12:217. 2011
    ....
  13. pmc Validation of quantitative magnetic resonance imaging-based apparent bone volume fraction in peri-articular tibial bone of cadaveric knees
    Jeffrey B Driban
    Division of Rheumatology, Tufts Medical Center, 800 Washington Street, Box 406, Boston, MA 02111, USA
    BMC Musculoskelet Disord 15:143. 2014
    ..g., micro-computed tomography [microCT]). In this cadaveric validation study we explored the association between MR-based apparent BV/TV and microCT-based BV/TV in the proximal peri-articular medial tibia...
  14. pmc Relationship of bone mineral density to progression of knee osteoarthritis
    Ji Y Lee
    Tufts Medical Center, Boston, MA 02111, USA
    Arthritis Rheum 65:1541-6. 2013
    ..To evaluate the longitudinal relationship between bone mineral density (BMD) and BMD changes and the progression of knee osteoarthritis (OA), as measured by cartilage outcomes...
  15. pmc Is lipstick associated with the development of systemic lupus erythematosus (SLE)?
    Jun Wang
    Division of Rheumatology, Tufts Medical Center, Boston, MA 02111, USA
    Clin Rheumatol 27:1183-7. 2008
    ..Epidemiologic studies of SLE should include this exposure in exploring its environmental triggers...
  16. ncbi request reprint Glucosamine for pain in osteoarthritis: why do trial results differ?
    Steven C Vlad
    Boston University Medical Center, Boston, Massachusetts 02118, USA
    Arthritis Rheum 56:2267-77. 2007
    ..Investigators in trials of glucosamine report a range of estimates for efficacy, making conclusions difficult. We undertook this study to identify factors that explain heterogeneity in trials of glucosamine...
  17. ncbi request reprint Nutritional factors and osteoarthritis: recent developments
    Timothy E McAlindon
    Tufts New England Medical Center, Boston, MA 02111, USA
    Curr Opin Rheumatol 17:647-52. 2005
    ..This review focuses on how the evidence for a role of nutritional factors or nutritional supplements in the management of knee osteoarthritis has been changed by recent research...
  18. ncbi request reprint Nutraceuticals: do they work and when should we use them?
    Timothy E McAlindon
    Tufts New England Medical Center, Boston, MA 02111, USA
    Best Pract Res Clin Rheumatol 20:99-115. 2006
    ....
  19. ncbi request reprint Small vessel vasculitis in a patient with botryomycosis
    Monica J Snowden
    Division of Rheumatology, Tufts University, Boston, Massachusetts 02111, USA
    J Rheumatol 33:2545-7. 2006
    ..With guidance from the skin biopsy findings, the patient was appropriately treated with antibiotics, resulting in complete resolution of symptoms...
  20. ncbi request reprint Relative efficacy of hyaluronic acid in comparison with NSAIDs for knee osteoarthritis: a systematic review and meta-analysis
    Raveendhara R Bannuru
    Center for Treatment Comparison and Integrative Analysis CTCIA, Tufts Medical Center, 800 Washington St 63, Boston, MA 02111 Division of Rheumatology, Tufts Medical Center, Boston, MA Electronic address
    Semin Arthritis Rheum 43:593-9. 2014
    ..To assess the relative efficacy of intra-articular hyaluronic acid (IAHA) in comparison with non-steroidal anti-inflammatory drugs (NSAIDs) for knee osteoarthritis (OA)...
  21. doi request reprint Therapeutic trajectory of hyaluronic acid versus corticosteroids in the treatment of knee osteoarthritis: a systematic review and meta-analysis
    Raveendhara R Bannuru
    Tufts University School of Medicine, Boston, MA, USA
    Arthritis Rheum 61:1704-11. 2009
    ..To compare the efficacy of intraarticular hyaluronic acid with corticosteroids for knee osteoarthritis (OA)...
  22. ncbi request reprint Considerations in the treatment of early osteoarthritis
    Senada Arabelovic
    Tufts New England Medical Center, Division of Rheumatology, 750 Washington Street, NEMC Box 406, Boston, MA 02111, USA
    Curr Rheumatol Rep 7:29-35. 2005
    ....
  23. ncbi request reprint Effect of glutathione S-transferase polymorphisms and proximity to hazardous waste sites on time to systemic lupus erythematosus diagnosis: results from the Roxbury lupus project
    Elizabeth W Karlson
    Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Arthritis Rheum 56:244-54. 2007
    ..Our goal was to assess association of residential proximity to hazardous waste sites and genetic variation in 3 glutathione Stransferase (GST) genes (GSTM1, GSTT1, and GSTP1) with age at diagnosis of SLE...

Research Grants12

  1. Trial of Vitamin D to Reduce Progression of Knee OA
    Timothy McAlindon; Fiscal Year: 2007
    ..We will test effectiveness of vitamin D using cross-sectional time series regression models with first-order autoregressive disturbance adjusting for informative dropouts. ..
  2. FEASIBILITY OF INTERNET-BASED TRIALS FOR OSTEOARTHRITIS
    Timothy McAlindon; Fiscal Year: 2000
    ..abstract_text> ..
  3. FEASIBILITY OF INTERNET-BASED TRIALS FOR OSTEOARTHRITIS
    Timothy McAlindon; Fiscal Year: 2001
    ..abstract_text> ..
  4. Trial of Vitamin D to Reduce Progression of Knee OA
    Timothy McAlindon; Fiscal Year: 2005
    ..We will test effectiveness of vitamin D using cross-sectional time series regression models with first-order autoregressive disturbance adjusting for informative dropouts. ..
  5. The Role of Bone in Osteoarthritis Progression
    Timothy McAlindon; Fiscal Year: 2009
    ..All these data will join and enrich the OAI public data set at specified time points. ..
  6. The Role of Bone in Osteoarthritis Progression
    Timothy E McAlindon; Fiscal Year: 2010
    ..All these data will join and enrich the OAI public data set at specified time points. ..
  7. FEASIBILITY OF INTERNET-BASED TRIALS FOR OSTEOARTHRITIS
    Timothy McAlindon; Fiscal Year: 1999
    ..abstract_text> ..
  8. Trial of Vitamin D to Reduce Progression of Knee OA
    Timothy McAlindon; Fiscal Year: 2006
    ..We will test effectiveness of vitamin D using cross-sectional time series regression models with first-order autoregressive disturbance adjusting for informative dropouts. ..
  9. FEASIBILITY OF INTERNET-BASED TRIALS FOR OSTEOARTHRITIS
    Timothy McAlindon; Fiscal Year: 2000
    ..abstract_text> ..
  10. Effect of Intra-Articular Steroids on Structural Progression of Knee OA: An RCT
    Timothy E McAlindon; Fiscal Year: 2010
    ..Confirmation of this hypothesis would lead to an easily-deployable and inexpensive disease-modification strategy for knee OA. ..