Andrew S Levey

Summary

Affiliation: Tufts Medical Center
Country: USA

Publications

  1. doi request reprint Conceptual model of CKD: applications and implications
    Andrew S Levey
    Division of Nephrology, Tufts Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 53:S4-16. 2009
  2. doi request reprint Comprehensive public health strategies for preventing the development, progression, and complications of CKD: report of an expert panel convened by the Centers for Disease Control and Prevention
    Andrew S Levey
    Division of Nephrology, Tufts Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 53:522-35. 2009
  3. doi request reprint The definition, classification, and prognosis of chronic kidney disease: a KDIGO Controversies Conference report
    Andrew S Levey
    Division of Nephrology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts, USA
    Kidney Int 80:17-28. 2011
  4. doi request reprint Chronic kidney disease, diabetes, and hypertension: what's in a name?
    Andrew S Levey
    Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Kidney Int 78:19-22. 2010
  5. doi request reprint Living donor kidney transplantation in the United States--looking back, looking forward
    Andrew S Levey
    Division of Nephrology, Tufts Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 58:343-8. 2011
  6. doi request reprint Chronic kidney disease
    Andrew S Levey
    William B Schwartz Division of Nephrology, Tufts Medical Center, Boston, MA 02111, USA
    Lancet 379:165-80. 2012
  7. doi request reprint Waist-to-hip ratio, body mass index, and subsequent kidney disease and death
    Essam F Elsayed
    Nephrology Research Center, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 52:29-38. 2008
  8. pmc Waist-to-hip ratio and body mass index as risk factors for cardiovascular events in CKD
    Essam F Elsayed
    Department of Medicine, Tufts Medical Center, Boston, MA, USA
    Am J Kidney Dis 52:49-57. 2008
  9. ncbi request reprint Factors associated with lipoprotein(a) in chronic kidney disease
    Katrin Uhlig
    Department of Medicine, Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 45:28-38. 2005
  10. ncbi request reprint Relationship between C-reactive protein, albumin, and cardiovascular disease in patients with chronic kidney disease
    Vandana Menon
    Department of Medicine, Division of Clinical Care Research, Tufts New England Medical Center, Boston, MA, USA
    Am J Kidney Dis 42:44-52. 2003

Collaborators

Detail Information

Publications91

  1. doi request reprint Conceptual model of CKD: applications and implications
    Andrew S Levey
    Division of Nephrology, Tufts Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 53:S4-16. 2009
    ....
  2. doi request reprint Comprehensive public health strategies for preventing the development, progression, and complications of CKD: report of an expert panel convened by the Centers for Disease Control and Prevention
    Andrew S Levey
    Division of Nephrology, Tufts Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 53:522-35. 2009
    ..Cooperation among federal, state, and local governmental and private organizations will be necessary to carry out these recommendations...
  3. doi request reprint The definition, classification, and prognosis of chronic kidney disease: a KDIGO Controversies Conference report
    Andrew S Levey
    Division of Nephrology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts, USA
    Kidney Int 80:17-28. 2011
    ..KDIGO has now convened a workgroup to develop a global clinical practice guideline for the definition, classification, and prognosis of chronic kidney disease...
  4. doi request reprint Chronic kidney disease, diabetes, and hypertension: what's in a name?
    Andrew S Levey
    Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Kidney Int 78:19-22. 2010
    ..We provide data on the frequency of diabetes, hypertension, or both, according to albumin-to-creatinine ratio and eGFR, and review the rationale for retaining the current name...
  5. doi request reprint Living donor kidney transplantation in the United States--looking back, looking forward
    Andrew S Levey
    Division of Nephrology, Tufts Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 58:343-8. 2011
    ....
  6. doi request reprint Chronic kidney disease
    Andrew S Levey
    William B Schwartz Division of Nephrology, Tufts Medical Center, Boston, MA 02111, USA
    Lancet 379:165-80. 2012
    ..In this Seminar we discuss disease burden, recommendations for assessment and management, and future challenges. We emphasise clinical practice guidelines, clinical trials, and areas of uncertainty...
  7. doi request reprint Waist-to-hip ratio, body mass index, and subsequent kidney disease and death
    Essam F Elsayed
    Nephrology Research Center, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 52:29-38. 2008
    ..Chronic kidney disease (CKD) and obesity are important public health concerns. We examined the association between anthropomorphic measures and incident CKD and mortality...
  8. pmc Waist-to-hip ratio and body mass index as risk factors for cardiovascular events in CKD
    Essam F Elsayed
    Department of Medicine, Tufts Medical Center, Boston, MA, USA
    Am J Kidney Dis 52:49-57. 2008
    ..Waist-to-hip ratio (WHR) is less influenced by muscle and bone mass than body mass index (BMI). We compared WHR and BMI as risk factors for cardiac events (myocardial infarction and fatal coronary disease) in persons with CKD...
  9. ncbi request reprint Factors associated with lipoprotein(a) in chronic kidney disease
    Katrin Uhlig
    Department of Medicine, Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 45:28-38. 2005
    ....
  10. ncbi request reprint Relationship between C-reactive protein, albumin, and cardiovascular disease in patients with chronic kidney disease
    Vandana Menon
    Department of Medicine, Division of Clinical Care Research, Tufts New England Medical Center, Boston, MA, USA
    Am J Kidney Dis 42:44-52. 2003
    ..Data are limited regarding relationships between CRP levels and glomerular filtration rate (GFR), nutritional indices, and CVD in patients with earlier stages of kidney disease...
  11. doi request reprint A predictive model for progression of chronic kidney disease to kidney failure
    Navdeep Tangri
    Department of Medicine, Tufts Medical Center, 800 Washington St, PO Box 391, Boston, MA 02111, USA
    JAMA 305:1553-9. 2011
    ....
  12. ncbi request reprint Relationship of phosphorus and calcium-phosphorus product with mortality in CKD
    Vandana Menon
    Division of Nephrology, Department of Medicine, Tufts New England Medical Center, Boston, MA, USA
    Am J Kidney Dis 46:455-63. 2005
    ..There are limited data investigating relationships of phosphorus and calcium-phosphorus product with outcomes in patients with chronic kidney disease (CKD) stages 3 to 4...
  13. ncbi request reprint The Framingham predictive instrument in chronic kidney disease
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    J Am Coll Cardiol 50:217-24. 2007
    ..We sought to determine the utility of the Framingham equations in individuals with chronic kidney disease (CKD)...
  14. pmc Role of adipose tissue in determining muscle mass in patients with chronic kidney disease
    Carmen Castaneda-Sceppa
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    J Ren Nutr 17:314-22. 2007
    ..Arm muscle area was used as an indicator of muscle mass...
  15. doi request reprint The relationship between nontraditional risk factors and outcomes in individuals with stage 3 to 4 CKD
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 51:212-23. 2008
    ..Chronic kidney disease is associated with increased risk for cardiovascular disease and mortality. Both traditional and nontraditional cardiovascular disease risk factors may contribute...
  16. doi request reprint A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease
    Marc A Pfeffer
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    N Engl J Med 361:2019-32. 2009
    ..Although darbepoetin alfa can effectively increase hemoglobin levels, its effect on clinical outcomes in these patients has not been adequately tested...
  17. ncbi request reprint Glycosylated hemoglobin and mortality in patients with nondiabetic chronic kidney disease
    Vandana Menon
    Department of Medicine, Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts, USA
    J Am Soc Nephrol 16:3411-7. 2005
    ..43; P = 0.07). HbA(1c) is associated with increased mortality in nondiabetic kidney disease. Hyperglycemia may be a potential therapeutic target and HbA(1c) may be important as a risk stratification tool in this high-risk population...
  18. doi request reprint Erythropoietic response and outcomes in kidney disease and type 2 diabetes
    Scott D Solomon
    Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02114, USA
    N Engl J Med 363:1146-55. 2010
    ..However, target-based strategies are confounded by each patient's individual hematopoietic response...
  19. pmc Interferon for hepatitis C virus in hemodialysis--an individual patient meta-analysis of factors associated with sustained virological response
    Craig E Gordon
    Division of Nephrology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts, USA
    Clin J Am Soc Nephrol 4:1449-58. 2009
    ..The authors aimed to identify factors associated with SVR in hemodialysis patients through analysis of individual patient data obtained from systematic review of published literature...
  20. ncbi request reprint Cystatin C as a risk factor for outcomes in chronic kidney disease
    Vandana Menon
    Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Ann Intern Med 147:19-27. 2007
    ....
  21. ncbi request reprint Relationship between homocysteine and mortality in chronic kidney disease
    Vandana Menon
    Division of Nephrology, Department of Medicine, Tufts New England Medical Center, Boston, MA, USA
    Circulation 113:1572-7. 2006
    ..The relationship between total homocysteine (tHcy) and outcomes has not been investigated in patients with chronic kidney disease stages 3 to 4...
  22. doi request reprint Effect of a very low-protein diet on outcomes: long-term follow-up of the Modification of Diet in Renal Disease (MDRD) Study
    Vandana Menon
    Department of Medicine, Division of Nephrology, Tufts Medical Center, Boston, MA, USA
    Am J Kidney Dis 53:208-17. 2009
    ..We examined the effect of a very low-protein diet on the development of kidney failure and death during long-term follow-up of the Modification of Diet in Renal Disease (MDRD) Study...
  23. ncbi request reprint Predicting 1 year mortality in an outpatient haemodialysis population: a comparison of comorbidity instruments
    Dana C Miskulin
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Nephrol Dial Transplant 19:413-20. 2004
    ..We compare the discriminatory accuracy of 1 year mortality predictions derived from four comorbidity instruments in a large representative US dialysis population...
  24. ncbi request reprint Early, intermediate, and long-term risk factors for mortality in incident dialysis patients: the Choices for Healthy Outcomes in Caring for ESRD (CHOICE) Study
    Laura C Plantinga
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Kidney Dis 49:831-40. 2007
    ..Knowing whether risk factors for mortality differ in dialysis patients who survive longer and the strengths of these risk factors for mortality change over time would assist physicians in making better prognostic judgments...
  25. ncbi request reprint Anemia as a risk factor for cardiovascular disease and all-cause mortality in diabetes: the impact of chronic kidney disease
    Panagiotis T Vlagopoulos
    Division of Nephrology, Tufts New England Medical Center, 750 Washington Street, Box 391, Boston, MA 02111, USA
    J Am Soc Nephrol 16:3403-10. 2005
    ..66) for all-cause mortality. Anemia was not a risk factor for any outcome in those without CKD (P > 0.2 for all outcomes). In persons with diabetes, anemia is primarily a risk factor for adverse outcomes in those who also have CKD...
  26. pmc Uric acid and long-term outcomes in CKD
    Magdalena Madero
    Department of Medicine, Division of Nephrology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Am J Kidney Dis 53:796-803. 2009
    ..Hyperuricemia is prevalent in patients with chronic kidney disease (CKD); however, data are limited about the relationship of uric acid levels with long-term outcomes in this patient population...
  27. pmc Serum β-trace protein and risk of mortality in incident hemodialysis patients
    Tariq Shafi
    Division of Nephrology, Johns Hopkins University School of Medicine, 301 Mason Lord Drive, Suite 2500, Baltimore, MD 21224 2780, USA
    Clin J Am Soc Nephrol 7:1435-45. 2012
    ..The objective of this study was to determine the association of serum β-trace protein with mortality in incident hemodialysis patients...
  28. ncbi request reprint Progression of chronic kidney disease: the role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition: a patient-level meta-analysis
    Tazeen H Jafar
    Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Ann Intern Med 139:244-52. 2003
    ..Angiotensin-converting enzyme (ACE) inhibitors reduce blood pressure and urine protein excretion and slow the progression of chronic kidney disease...
  29. ncbi request reprint Cardiovascular disease and subsequent kidney disease
    Essam F Elsayed
    Division of Nephrology, Department of Medicine, Tufts New England Medical Center, Campus Box 391, Boston, MA 02111
    Arch Intern Med 167:1130-6. 2007
    ..Chronic kidney disease is a risk factor for cardiovascular disease (CVD); however, it is uncertain if CVD is a risk factor for progression or development of kidney disease...
  30. ncbi request reprint Level of kidney function as a risk factor for cardiovascular outcomes in the elderly
    Guruprasad Manjunath
    Department of Medicine, New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA
    Kidney Int 63:1121-9. 2003
    ..We evaluated whether the level of kidney function is an independent risk factor for CVD outcomes in the Cardiovascular Health Study (CHS), a cohort of subjects whose age at baseline was 65 years old or older...
  31. ncbi request reprint Comorbidity and its change predict survival in incident dialysis patients
    Dana C Miskulin
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 41:149-61. 2003
    ..Longitudinal change in the comorbid illness burden of incident dialysis patients has not been measured. Comorbidity severity and its change may serve as important prognostic markers of survival, independent of other case-mix factors...
  32. ncbi request reprint The rate of progression of renal disease may not be slower in women compared with men: a patient-level meta-analysis
    Tazeen H Jafar
    New England Medical Center, Tufts University School of Medicine, Boston, MA, USA
    Nephrol Dial Transplant 18:2047-53. 2003
    ..Therefore, we undertook this analysis to explore the independent association of renal disease progression with gender...
  33. doi request reprint Factors other than glomerular filtration rate affect serum cystatin C levels
    Lesley A Stevens
    Division of Nephrology, Clinical Care Research, Tufts Medical Center, Boston, Massachusetts 02111, USA
    Kidney Int 75:652-60. 2009
    ..Hence, we found that cystatin C is affected by factors other than GFR which should be considered when the GFR is estimated using serum levels of cystatin C...
  34. pmc Estimating GFR using serum cystatin C alone and in combination with serum creatinine: a pooled analysis of 3,418 individuals with CKD
    Lesley A Stevens
    Division of Nephrology, Tufts New England Medical Center, 750 Washington St, Box 391, Boston, MA 02111, USA
    Am J Kidney Dis 51:395-406. 2008
    ..We report the development and evaluation of GFR-estimating equations using serum cystatin C alone and serum cystatin C, serum creatinine, or both with demographic variables...
  35. ncbi request reprint Kidney disease as a risk factor for recurrent cardiovascular disease and mortality
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 44:198-206. 2004
    ..Few studies have evaluated the effect of CKD on cardiovascular events in a diverse community-based population with underlying CVD...
  36. ncbi request reprint Homocysteine in chronic kidney disease: Effect of low protein diet and repletion with B vitamins
    Vandana Menon
    Department of Medicine, Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Kidney Int 67:1539-46. 2005
    ..Data are limited on the determinants of homocysteine (tHcy) and its relationship with nutritional indices, and dietary protein intake, in the earlier stages of chronic kidney disease (CKD)...
  37. ncbi request reprint Body mass index and mortality in CKD
    Magdalena Madero
    Department of Medicine, Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 50:404-11. 2007
    ..Data are limited on the relationship of BMI with mortality in patients in the earlier stages of chronic kidney disease (CKD)...
  38. pmc A new equation to estimate glomerular filtration rate
    Andrew S Levey
    Tufts Medical Center, Boston, Massachusetts 02111, USA
    Ann Intern Med 150:604-12. 2009
    ..Equations to estimate glomerular filtration rate (GFR) are routinely used to assess kidney function. Current equations have limited precision and systematically underestimate measured GFR at higher values...
  39. ncbi request reprint C-reactive protein and albumin as predictors of all-cause and cardiovascular mortality in chronic kidney disease
    Vandana Menon
    Department of Medicine, Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Kidney Int 68:766-72. 2005
    ..There are limited data evaluating the relationships between CRP, albumin, and outcomes in chronic kidney disease (CKD) stages 3 and 4...
  40. ncbi request reprint The effect of angiotensin-converting-enzyme inhibitors on progression of advanced polycystic kidney disease
    Tazeen H Jafar
    Division of Nephrology, New England Medical Center, Boston, Massachusetts, USA
    Kidney Int 67:265-71. 2005
    ..We performed a patient-level meta-analysis to compare the effect of antihypertensive regimens, including ACE inhibitors, to those without ACE inhibitors (controls) on kidney disease progression in patients with PKD...
  41. ncbi request reprint Effect of dietary protein restriction on the progression of kidney disease: long-term follow-up of the Modification of Diet in Renal Disease (MDRD) Study
    Andrew S Levey
    Division of Nephrology, Tufts New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Am J Kidney Dis 48:879-88. 2006
    ..We evaluated effects of protein restriction on kidney failure and all-cause mortality during extended follow-up of the Modification of Diet in Renal Disease Study...
  42. ncbi request reprint Proteinuria and other markers of chronic kidney disease: a position statement of the national kidney foundation (NKF) and the national institute of diabetes and digestive and kidney diseases (NIDDK)
    Garabed Eknoyan
    Department of Medicine, Baylor College of Medicine, Houston, TX, USA
    Am J Kidney Dis 42:617-22. 2003
  43. doi request reprint Changes in dietary protein intake has no effect on serum cystatin C levels independent of the glomerular filtration rate
    Navdeep Tangri
    Division of Nephrology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts 02111, USA
    Kidney Int 79:471-7. 2011
    ..Hence, cystatin C may allow more accurate estimates of GFR than creatinine for patients with reduced protein intake. Further study of other non-GFR determinants of cystatin C is needed before the widespread adoption...
  44. ncbi request reprint Impact of creatinine calibration on performance of GFR estimating equations in a pooled individual patient database
    Lesley A Stevens
    Division of Nephrology, Tufts New England Medical Center, 750 Washington St, Box 391, Boston, MA 02111, USA
    Am J Kidney Dis 50:21-35. 2007
    ..Variation in performance of glomerular filtration rate (GFR) estimating equations is related to variation in calibration of the creatinine assay across clinical laboratories...
  45. doi request reprint Estimating glomerular filtration rate from serum creatinine and cystatin C
    Lesley A Inker
    Division of Nephrology, Tufts Medical Center, 800 Washington St, Box 391, Boston, MA 02111, USA
    N Engl J Med 367:20-9. 2012
    ..Cystatin C is an alternative filtration marker for estimating GFR...
  46. pmc Filtration markers may have prognostic value independent of glomerular filtration rate
    Navdeep Tangri
    Department of Medicine, Division of Nephrology, Tufts Medical Center, Boston, MA 02111, USA
    J Am Soc Nephrol 23:351-9. 2012
    ..trace protein and cystatin C seem to provide more consistent prognostic information than creatinine...
  47. pmc CKD classification based on estimated GFR over three years and subsequent cardiac and mortality outcomes: a cohort study
    Daniel E Weiner
    Division of Nephrology, Tufts Medical Center, 800 Washington Street, Boston, MA 02111, USA
    BMC Nephrol 10:26. 2009
    ..It is unknown whether defining chronic kidney disease (CKD) based on one versus two estimated glomerular filtration rate (eGFR) assessments changes the prognostic importance of reduced eGFR in a community-based population...
  48. ncbi request reprint Association between body mass index and CKD in apparently healthy men
    Rebecca P Gelber
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
    Am J Kidney Dis 46:871-80. 2005
    ..Conversely, their association with the development of CKD is less clear...
  49. ncbi request reprint Prevalence of ICD-9-CM codes for chronic kidney disease in individuals with cardiovascular disease risk factors
    Ashish Mahajan
    Tufts Medical Center Scientific and Clinical Research Center, Boston, Massachusetts, USA
    J Nephrol 22:523-33. 2009
    ..Chronic kidney disease (CKD) is a risk factor for cardiovascular disease (CVD)...
  50. ncbi request reprint The effect of a lower target blood pressure on the progression of kidney disease: long-term follow-up of the modification of diet in renal disease study
    Mark J Sarnak
    Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Ann Intern Med 142:342-51. 2005
    ..Hypertension is a risk factor for progression of chronic kidney disease. The optimal blood pressure to slow progression is unknown...
  51. pmc Agreement of self-reported comorbid conditions with medical and physician reports varied by disease among end-stage renal disease patients
    Sharon Stein Merkin
    Division of Geriatrics, Department of Medicine, Geffen School of Medicine, University of California Los Angeles, California, USA
    J Clin Epidemiol 60:634-42. 2007
    ..To compare self-report of eight diseases with review of medical records and physician reports...
  52. ncbi request reprint Adiponectin and mortality in patients with chronic kidney disease
    Vandana Menon
    Tufts New England Medical Center, Division of Nephrology, 750 Washington Street, NEMC 391, Boston, MA 02111, USA
    J Am Soc Nephrol 17:2599-606. 2006
    ..Further studies are necessary to confirm this association and to elucidate the underlying mechanisms...
  53. ncbi request reprint Level of kidney function as a risk factor for atherosclerotic cardiovascular outcomes in the community
    Guruprasad Manjunath
    Division of Nephrology, New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    J Am Coll Cardiol 41:47-55. 2003
    ....
  54. ncbi request reprint Cardiovascular outcomes and all-cause mortality: exploring the interaction between CKD and cardiovascular disease
    Daniel E Weiner
    Division of Nephrology, Department of Internal Medicine, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 48:392-401. 2006
    ..Concurrently, CVD may promote CKD, resulting in a vicious cycle. We evaluated this hypothesis by exploring whether CKD and CVD have an additive or synergistic effect on future cardiovascular and mortality outcomes...
  55. ncbi request reprint Lowest systolic blood pressure is associated with stroke in stages 3 to 4 chronic kidney disease
    Daniel E Weiner
    Division of Nephrology, Box 391, Tufts New England Medical Center, Boston, MA 02111, USA
    J Am Soc Nephrol 18:960-6. 2007
    ..CKD and elevated SBP are independent risk factors for incident stroke. In CKD, individuals with the lowest BP are at increased risk for stroke. This pattern is not seen in the general population...
  56. pmc Key comorbid conditions that are predictive of survival among hemodialysis patients
    Dana Miskulin
    Division of Nephrology, Tufts Medical Center, 800 Washington Street, Box 391, Boston, MA 02111, USA
    Clin J Am Soc Nephrol 4:1818-26. 2009
    ..We sought to determine which conditions are most prognostic and whether comorbidity continues to contribute to a survival model once laboratory and clinical parameters have been accounted for...
  57. pmc Comparative performance of the CKD Epidemiology Collaboration (CKD-EPI) and the Modification of Diet in Renal Disease (MDRD) Study equations for estimating GFR levels above 60 mL/min/1.73 m2
    Lesley A Stevens
    Tufts Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 56:486-95. 2010
    ..Here, performance of a more accurate GFR-estimating equation, the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation, is reported by level of GFR and clinical characteristics...
  58. ncbi request reprint Expressing the Modification of Diet in Renal Disease Study equation for estimating glomerular filtration rate with standardized serum creatinine values
    Andrew S Levey
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Clin Chem 53:766-72. 2007
    ..We sought to reexpress the 4-variable Modification of Diet in Renal Disease (MDRD) Study equation for estimation of glomerular filtration rate (GFR) using serum creatinine (S(cr)) standardized to reference methods...
  59. doi request reprint Cognitive dysfunction and depression in adult kidney transplant recipients: baseline findings from the FAVORIT Ancillary Cognitive Trial (FACT)
    Aron M Troen
    Nutrition and Neurocognition Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA
    J Ren Nutr 22:268-76.e1-3. 2012
    ..Accordingly, we assessed the prevalence of cognitive impairment and depressive symptoms in transplant recipients and their association with kidney function, plasma total homocysteine, and B-vitamin concentrations...
  60. pmc Development and validation of GFR-estimating equations using diabetes, transplant and weight
    Lesley A Stevens
    Tufts Medical Center, Boston, MA, USA
    Nephrol Dial Transplant 25:449-57. 2010
    ..Here, we describe the development and validation of this equation as well as other equations that incorporate diabetes, transplant and weight as additional predictor variables...
  61. doi request reprint Association between cardiac biomarkers and the development of ESRD in patients with type 2 diabetes mellitus, anemia, and CKD
    Akshay S Desai
    Cardiovascular Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    Am J Kidney Dis 58:717-28. 2011
    ..We examined the value of troponin T (TnT) and N-terminal pro-brain natriuretic peptide (NT-pro-BNP) in assessing the risk of developing end-stage renal disease (ESRD) in diabetic patients with CKD...
  62. doi request reprint Baseline characteristics in the Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT)
    Marc A Pfeffer
    Cardiovascular Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    Am J Kidney Dis 54:59-69. 2009
    ....
  63. ncbi request reprint Assessing kidney function--measured and estimated glomerular filtration rate
    Lesley A Stevens
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    N Engl J Med 354:2473-83. 2006
  64. ncbi request reprint Demographics and trends in overweight and obesity in patients at time of kidney transplantation
    Allon N Friedman
    Division of Nephrology, Indiana University School of Medicine, Indianapolis, IN, USA
    Am J Kidney Dis 41:480-7. 2003
    ..The authors describe the prevalence, demographics, and trends in overweight and obesity at the time of kidney transplantation...
  65. ncbi request reprint Frequency of sit-down patient care rounds, attainment of clinical performance targets, hospitalization, and mortality in hemodialysis patients
    Laura C Plantinga
    Welch Center for Prevention, Epidemiology and Clinical Research, Department of Medicine, Johns Hopkins Medical Institutions, 2024 E Monument Street, Suite 2 600, Baltimore, MD 21205, USA
    J Am Soc Nephrol 15:3144-53. 2004
    ..This association may be due to the positive effect of collaborative discussion by the patient care team of short- and long-term care goals for individual patients...
  66. ncbi request reprint Progression risk, urinary protein excretion, and treatment effects of angiotensin-converting enzyme inhibitors in nondiabetic kidney disease
    David M Kent
    Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, 750 Washington Street 63, Boston, MA 02111, USA
    J Am Soc Nephrol 18:1959-65. 2007
    ..Patients with proteinuria <500 mg/d do not seem to benefit, even when at relatively high risk for progression...
  67. ncbi request reprint Effects of anemia and left ventricular hypertrophy on cardiovascular disease in patients with chronic kidney disease
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, 750 Washington Street, Box 391, Boston, MA 02111, USA
    J Am Soc Nephrol 16:1803-10. 2005
    ..15 [95% CI, 2.62 to 6.56] and 3.92 [95% CI, 2.05 to 7.48]; P = 0.02 and 0.01 for interaction term, respectively). The combination of anemia and LVH in CKD identifies a high-risk population...
  68. ncbi request reprint Chronic kidney disease as a risk factor for cardiovascular disease and all-cause mortality: a pooled analysis of community-based studies
    Daniel E Weiner
    Division of Nephrology, Department of Clinical Care Research, Tufts New England Medical Center, Boston, Massachusetts, USA
    J Am Soc Nephrol 15:1307-15. 2004
    ..It is hypothesized that this effect may be due to more frequent or more severe subclinical vascular disease secondary to hypertension or diabetes in black individuals...
  69. ncbi request reprint Serum C-reactive protein and leptin as predictors of kidney disease progression in the Modification of Diet in Renal Disease Study
    Mark J Sarnak
    New England Medical Center and Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Kidney Int 62:2208-15. 2002
    ..In vitro and in vivo data suggest that markers of inflammation and nutritional status may be risk factors for the progression of chronic kidney disease...
  70. ncbi request reprint Kidney disease, Framingham risk scores, and cardiac and mortality outcomes
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, Mass 02111, USA
    Am J Med 120:552.e1-8. 2007
    ..The Framingham equations were developed to predict incident coronary heart disease. It remains unknown how the presence of chronic kidney disease affects their performance...
  71. ncbi request reprint Low rates of testing and diagnostic codes usage in a commercial clinical laboratory: evidence for lack of physician awareness of chronic kidney disease
    Lesley A Stevens
    Tufts New England Medical Center, 750 Washington Street, Box 391, Boston, MA 02111, USA
    J Am Soc Nephrol 16:2439-48. 2005
    ....
  72. ncbi request reprint Comorbidity and other factors associated with modality selection in incident dialysis patients: the CHOICE Study. Choices for Healthy Outcomes in Caring for End-Stage Renal Disease
    Dana C Miskulin
    Division of Nephrology, New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 39:324-36. 2002
    ..Adjustment for case-mix differences in patients treated with PD versus HD is essential to the assessment of the independent effect of the dialysis modality on outcomes...
  73. doi request reprint Proteinuria as a surrogate outcome in CKD: report of a scientific workshop sponsored by the National Kidney Foundation and the US Food and Drug Administration
    Andrew S Levey
    Tufts Medical Center, Boston, MA, USA
    Am J Kidney Dis 54:205-26. 2009
    ..We recommend collaboration among many groups, including academia, industry, the FDA, and the National Institutes of Health, to share data from past and future studies...
  74. ncbi request reprint Surrogate end points for clinical trials of kidney disease progression
    Lesley A Stevens
    Division of Nephrology, Tufts New England Medical Center, 750 Washington Street, Box 391, Boston, MA 02111, USA
    Clin J Am Soc Nephrol 1:874-84. 2006
  75. doi request reprint Evaluation of the Chronic Kidney Disease Epidemiology Collaboration equation for estimating the glomerular filtration rate in multiple ethnicities
    Lesley A Stevens
    Division of Nephrology, Tufts Medical Center, Boston, Massachusetts 02111, USA
    Kidney Int 79:555-62. 2011
    ..Thus, heterogeneity in performance among the ethnic and geographic groups precludes use of the four-level race equation. The CKD-EPI two-level race equation can be used in the United States and Europe across a wide range of ethnicity...
  76. doi request reprint Nephrotic syndrome in diabetic kidney disease: an evaluation and update of the definition
    Nicholas Stoycheff
    Division of Nephrology, Tufts Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 54:840-9. 2009
    ..These threshold levels have not been rigorously evaluated in patients with diabetic kidney disease or by using urine albumin excretion, the preferred measure of proteinuria in patients with diabetes...
  77. pmc Albuminuria, cognitive functioning, and white matter hyperintensities in homebound elders
    Daniel E Weiner
    Division of Nephrology, Tufts Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 53:438-47. 2009
    ..Albuminuria, a kidney marker of microvascular disease, may herald microvascular disease elsewhere, including in the brain...
  78. ncbi request reprint Traditional cardiac risk factors in individuals with chronic kidney disease
    Katrin Uhlig
    Division of Nephrology, Department of Medicine, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Semin Dial 16:118-27. 2003
    ..Treatment recommendations are provided using evidence available from populations with CKD or evidence extrapolated from the general population when there are insufficient data on individuals with CKD...
  79. pmc Comparison of drug dosing recommendations based on measured GFR and kidney function estimating equations
    Lesley A Stevens
    Division of Nephrology, Tufts Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 54:33-42. 2009
    ....
  80. ncbi request reprint Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO)
    Andrew S Levey
    Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Kidney Int 67:2089-100. 2005
    ..Kidney disease treatment by dialysis and transplantation should be noted. Simple, uniform classifications of CKD by cause and by risks for kidney disease progression and CVD should be developed...
  81. ncbi request reprint Automatic reporting of estimated glomerular filtration rate--just what the doctor ordered
    Andrew S Levey
    Division of Nephrology, Department of Medicine, Tufts New England Medical Center, Boston, MA 02111, USA
    Clin Chem 52:2188-93. 2006
  82. doi request reprint Measured GFR as a confirmatory test for estimated GFR
    Lesley A Stevens
    Tufts Medical Center, Boston, Massachusetts, USA
    J Am Soc Nephrol 20:2305-13. 2009
    ..We suggest plasma clearance of nonradioactive markers be more widely implemented in clinical settings. Further research is necessary on the impact of the use of measured GFR as a confirmatory test...
  83. doi request reprint Current status and future perspectives for CKD testing
    Lesley A Stevens
    Division of Nephrology, Tufts Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 53:S17-26. 2009
    ..Repeated testing for urine protein and interpretation of GFR estimates in the context of kidney damage and the clinical context of patient presentation can help overcome these limitations...
  84. doi request reprint Cystatin C and creatinine in an HIV cohort: the nutrition for healthy living study
    Clara Y Jones
    Tufts University School of Medicine, Boston, MA 02111, USA
    Am J Kidney Dis 51:914-24. 2008
    ..Serum creatinine level may underestimate the prevalence of CKD in subjects with decreased lean body mass or liver disease. Level of serum cystatin C, an alternative kidney function marker, is independent of lean body mass...
  85. doi request reprint Impact of reporting estimated glomerular filtration rate: it's not just about us
    Lesley A Stevens
    Tufts Medical Center, Boston, Massachusetts 02111, USA
    Kidney Int 76:245-7. 2009
    ..In our view, a complete assessment requires a broader perspective. Most patients with CKD do not require referral to a nephrologist. Improving outcomes requires coordinated efforts of all physicians...
  86. pmc Advances in glomerular filtration rate-estimating equations
    Lesley A Stevens
    Division of Nephrology, Tufts Medical Center, Boston, Massachusetts 02111, USA
    Curr Opin Nephrol Hypertens 19:298-307. 2010
    ..Here, we review the performance of current creatinine and cystatin C-based estimating equations as well as demonstration of their utility in public health and clinical practice...
  87. pmc Early change in proteinuria as a surrogate outcome in kidney disease progression: a systematic review of previous analyses and creation of a patient-level pooled dataset
    Nicholas Stoycheff
    Tufts Medical Center, Boston, MA, USA
    Nephrol Dial Transplant 26:848-57. 2011
    ..There is a reasonably sound biological basis for this hypothesis, but only preliminary empirical evidence currently exists...
  88. ncbi request reprint Ethnic subgroup differences in hypertension in Pakistan
    Tazeen H Jafar
    Department of Community Health Sciences, Tufts University Medical School, Boston, Massachusetts, USA
    J Hypertens 21:905-12. 2003
    ..We conducted this study to explore the variations in hypertension within ethnic subgroups among South Asians...
  89. ncbi request reprint Evaluation of the modification of diet in renal disease study equation in a large diverse population
    Lesley A Stevens
    Division of Nephrology, Tufts New England Medical Center, 750 Washington Street, Box 391, Boston, MA 02111, USA
    J Am Soc Nephrol 18:2749-57. 2007
    ..73 m(2). In individual patients, interpretation of GFR estimates near 60 ml/min per 1.73 m(2) should be interpreted with caution to avoid misclassification of chronic kidney disease in the context of the clinical setting...
  90. ncbi request reprint National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification
    Andrew S Levey
    Tufts New England Medical Center and Tufts University School of Medicine, Boston, Massachusetts, USA
    Ann Intern Med 139:137-47. 2003
    ..Because of the high prevalence of early stages of chronic kidney disease in the general population (approximately 11% of adults), this information is particularly important for general internists and specialists...
  91. ncbi request reprint Should the K/DOQI definition of chronic kidney disease be changed?
    Andrew S Levey
    Division of Nephrology, Tufts University School of Medicine, Tufts New England Medical Center, Boston, MA, USA
    Am J Kidney Dis 42:626-30. 2003