Susan S Harris

..This study was conducted to determine whether vitamin D supplementation improves insulin secretion, insulin sensitivity and glycaemia in African Americans with prediabetes or early diabetes...

..Greater adiposity is associated with lower blood levels of 25-hydroxyvitamin D [25(OH)D]. The extent to which this results from reduced sun exposure among heavier individuals is unknown...

..Clinicians and educators should be encouraged to promote improved vitamin D status among blacks (and others) because of the low risk and low cost of vitamin D supplementation and its potentially broad health benefits...

..001) but had no effect on fasting plasma glucose, serum insulin, or HOMA-IR. In conclusion, bicarbonate supplementation does not appear to improve insulin sensitivity or glucose control in non-diabetic older adults...

..Because of the low 25(OH)D concentrations of many, if not most, African Americans, and the low risk associated with vitamin D supplementation, it is important to obtain more definitive answers to these questions...

..Bicarbonate has been implicated in bone health in older subjects on acid-producing diets in short-term studies...

..Osteocalcin has been reported to contribute to the regulation of glucose tolerance and insulin secretion and sensitivity in experimental animals...

..CONCLUSIONS: Diet changes that increase renal NAE are associated with increases in serum PTH, bone resorption, and calcium excretion over a 60-day period...

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..This is important in view of worldwide increases in overweight and obesity and the potential contribution of elevated PTH to morbidity and mortality...

..Protein is an essential component of muscle and bone. However, the acidic byproducts of protein metabolism may have a negative impact on the musculoskeletal system, particularly in older individuals with declining renal function...

..Mono- and polyunsaturated fats may have opposing effects on vitamin D absorption...

..We sought to compare the effects of combined calcium and vitamin D supplementation versus placebo on blood glucose and markers of inflammation in nondiabetic adults aged > or =65 years...

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..This study was conducted to determine whether there are age differences in the plasma parent vitamin D and 25-hydroxyvitamin D (25OHD) responses to eight weeks of supplementation with 20 microg/day of vitamin D3...

..Compatible with the long-standing concept that fat tissue is a storage site for vitamin D, fat tissue and serum vitamin D(3) concentrations were positively correlated...

..This study investigated whether serum 25-hydroxyvitamin D [25(OH)D] concentration was associated with lean body mass, muscle strength and physical performance in men...

..This method can thus be a useful approach to study potential relationships between muscle fiber subtypes and vitamin D receptor expression...

..There is currently no consensus on the effect of dietary protein intake on the skeleton, but there is some indication that low calcium intakes adversely influence the effect of dietary protein on fracture risk...

..94% for total body fat tissue, and 0.77% for total body nonfat soft tissue. We conclude that precision overall is excellent and that femoral neck precision can be improved with bilateral compared with the traditional single hip scans...

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..This suggests that the primary care physician is well positioned to bring about much needed change in the quality of care of fracture patients...

..Uninsured women may be at an even higher risk for vitamin D deficiency than others owing to low intake of dietary and supplemental vitamin D and limited sun exposure...

..In general, hormone concentrations do not appear to be meaningfully associated with grip strength or chair stand scores...

..Recommended calcium intakes are important for skeletal health and do not appear to increase the risk for iron deficiency in healthy people...