Research Topics
| Sung Nim HanSummaryAffiliation: Tufts University Country: USA Publications
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Detail Information
Publications
Impact of vitamin E on immune function and its clinical implicationsSung Nim Han
Tufts University, Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, 711 Washington Street, Boston, MA 02111, USA
Expert Rev Clin Immunol 2:561-7. 2006....
Age and vitamin E-induced changes in gene expression profiles of T cellsSung Nim Han
Nutritional Immunology Laboratory, Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
J Immunol 177:6052-61. 2006..Further studies are needed to determine whether these changes are due to the effects of aging at a single-cell level or to the shift in the ratio of naïve:memory T cells with age...
Vitamin E and gene expression in immune cellsSung Nim Han
Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
Ann N Y Acad Sci 1031:96-101. 2004..Aging had significant effects on genes involved in signal transduction, transcriptional regulation, and apoptosis pathways in T cells, while vitamin E had a significant effect on genes associated with the regulation of cell cycle...
Effect of a therapeutic lifestyle change diet on immune functions of moderately hypercholesterolemic humansSung Nim Han
Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
J Lipid Res 44:2304-10. 2003..This might be a clinically important benefit, considering the decline of T cell-mediated immune functions with aging and evidence of impaired immune function associated with hypercholesterolemia...
Effect of age on susceptibility to azoxymethane-induced colonic aberrant crypt foci formation in C57BL/6JNIA miceHeekyung Chung
Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
J Gerontol A Biol Sci Med Sci 58:B400-5. 2003..These age differences are not due to variations in cyclooxygenase-2 expression, cell proliferation, or AOM hydroxylase activity...
Effect of concomitant consumption of fish oil and vitamin E on T cell mediated function in the elderly: a randomized double-blind trialDayong Wu
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
J Am Coll Nutr 25:300-6. 2006..CONCLUSIONS: The immuno-enhancing effect of vitamin E in the elderly is dampened when it is concomitantly consumed with fish oil. This may be due to the smaller increase in plasma concentrations of vitamin E in the presence of fish oil...
Effect of concomitant consumption of fish oil and vitamin E on production of inflammatory cytokines in healthy elderly humansDayong Wu
D V M, Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
Ann N Y Acad Sci 1031:422-4. 2004....
Vitamin E and immune response in the aged: molecular mechanisms and clinical implicationsSimin Nikbin Meydani
Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
Immunol Rev 205:269-84. 2005..Further studies are needed to determine the signaling mechanisms involved in the upregulation of naive T-cell function by vitamin E as well as the specific mechanisms involved in reduction of risk for upper respiratory infections...
The effect of vitamin E on secondary bacterial infection after influenza infection in young and old miceRaina Gay
Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
Ann N Y Acad Sci 1031:418-21. 2004..E supplementation did not have a significant effect on SA infection alone. However, E supplementation abolished the priming effect of influenza on SA...
Vitamin E supplementation does not alter azoxymethane-induced colonic aberrant crypt foci formation in young or old miceHeekyung Chung
Jean Mayer U.S. Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
J Nutr 133:528-32. 2003..Whether vitamin E supplementation might be effective in reducing AOM-induced colon tumors is unclear...
Vitamin E and respiratory infection in the elderlySimin Nikbin Meydani
Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
Ann N Y Acad Sci 1031:214-22. 2004....
Effect of hydrogenated and saturated, relative to polyunsaturated, fat on immune and inflammatory responses of adults with moderate hypercholesterolemiaSung Nim Han
Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
J Lipid Res 43:445-52. 2002....
