Sung Nim Han

Summary

Affiliation: Tufts University
Country: USA

Publications

  1. ncbi request reprint Impact of vitamin E on immune function and its clinical implications
    Sung Nim Han
    Tufts University, Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, 711 Washington Street, Boston, MA 02111, USA
    Expert Rev Clin Immunol 2:561-7. 2006
  2. ncbi request reprint Age and vitamin E-induced changes in gene expression profiles of T cells
    Sung Nim Han
    Nutritional Immunology Laboratory, Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    J Immunol 177:6052-61. 2006
  3. ncbi request reprint Vitamin E and gene expression in immune cells
    Sung Nim Han
    Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Ann N Y Acad Sci 1031:96-101. 2004
  4. ncbi request reprint Effect of a therapeutic lifestyle change diet on immune functions of moderately hypercholesterolemic humans
    Sung Nim Han
    Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Lipid Res 44:2304-10. 2003
  5. ncbi request reprint Effect of age on susceptibility to azoxymethane-induced colonic aberrant crypt foci formation in C57BL/6JNIA mice
    Heekyung Chung
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
    J Gerontol A Biol Sci Med Sci 58:B400-5. 2003
  6. ncbi request reprint Effect of concomitant consumption of fish oil and vitamin E on production of inflammatory cytokines in healthy elderly humans
    Dayong Wu
    D V M, Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Ann N Y Acad Sci 1031:422-4. 2004
  7. ncbi request reprint Effect of concomitant consumption of fish oil and vitamin E on T cell mediated function in the elderly: a randomized double-blind trial
    Dayong Wu
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Am Coll Nutr 25:300-6. 2006
  8. ncbi request reprint The effect of vitamin E on secondary bacterial infection after influenza infection in young and old mice
    Raina Gay
    Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Ann N Y Acad Sci 1031:418-21. 2004
  9. ncbi request reprint Vitamin E and immune response in the aged: molecular mechanisms and clinical implications
    Simin Nikbin Meydani
    Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Immunol Rev 205:269-84. 2005
  10. ncbi request reprint Vitamin E supplementation does not alter azoxymethane-induced colonic aberrant crypt foci formation in young or old mice
    Heekyung Chung
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Nutr 133:528-32. 2003

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Impact of vitamin E on immune function and its clinical implications
    Sung Nim Han
    Tufts University, Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, 711 Washington Street, Boston, MA 02111, USA
    Expert Rev Clin Immunol 2:561-7. 2006
    ....
  2. ncbi request reprint Age and vitamin E-induced changes in gene expression profiles of T cells
    Sung Nim Han
    Nutritional Immunology Laboratory, Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    J Immunol 177:6052-61. 2006
    ..Further studies are needed to determine whether these changes are due to the effects of aging at a single-cell level or to the shift in the ratio of naïve:memory T cells with age...
  3. ncbi request reprint Vitamin E and gene expression in immune cells
    Sung Nim Han
    Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Ann N Y Acad Sci 1031:96-101. 2004
    ..Aging had significant effects on genes involved in signal transduction, transcriptional regulation, and apoptosis pathways in T cells, while vitamin E had a significant effect on genes associated with the regulation of cell cycle...
  4. ncbi request reprint Effect of a therapeutic lifestyle change diet on immune functions of moderately hypercholesterolemic humans
    Sung Nim Han
    Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Lipid Res 44:2304-10. 2003
    ..This might be a clinically important benefit, considering the decline of T cell-mediated immune functions with aging and evidence of impaired immune function associated with hypercholesterolemia...
  5. ncbi request reprint Effect of age on susceptibility to azoxymethane-induced colonic aberrant crypt foci formation in C57BL/6JNIA mice
    Heekyung Chung
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
    J Gerontol A Biol Sci Med Sci 58:B400-5. 2003
    ..These age differences are not due to variations in cyclooxygenase-2 expression, cell proliferation, or AOM hydroxylase activity...
  6. ncbi request reprint Effect of concomitant consumption of fish oil and vitamin E on production of inflammatory cytokines in healthy elderly humans
    Dayong Wu
    D V M, Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Ann N Y Acad Sci 1031:422-4. 2004
    ....
  7. ncbi request reprint Effect of concomitant consumption of fish oil and vitamin E on T cell mediated function in the elderly: a randomized double-blind trial
    Dayong Wu
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Am Coll Nutr 25:300-6. 2006
    ..To determine if concomitant consumption of fish oil and vitamin E would modify the vitamin E level needed for improving T cell mediated function in elderly...
  8. ncbi request reprint The effect of vitamin E on secondary bacterial infection after influenza infection in young and old mice
    Raina Gay
    Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Ann N Y Acad Sci 1031:418-21. 2004
    ..E supplementation did not have a significant effect on SA infection alone. However, E supplementation abolished the priming effect of influenza on SA...
  9. ncbi request reprint Vitamin E and immune response in the aged: molecular mechanisms and clinical implications
    Simin Nikbin Meydani
    Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Immunol Rev 205:269-84. 2005
    ..Further studies are needed to determine the signaling mechanisms involved in the upregulation of naive T-cell function by vitamin E as well as the specific mechanisms involved in reduction of risk for upper respiratory infections...
  10. ncbi request reprint Vitamin E supplementation does not alter azoxymethane-induced colonic aberrant crypt foci formation in young or old mice
    Heekyung Chung
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Nutr 133:528-32. 2003
    ..Whether vitamin E supplementation might be effective in reducing AOM-induced colon tumors is unclear...
  11. doi request reprint In vivo regulation of gene transcription by alpha- and gamma-tocopherol in murine T lymphocytes
    Jean Marc Zingg
    Vascular Biology Laboratory, JM USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Arch Biochem Biophys 538:111-9. 2013
    ..It is possible that the observed diminution in gene expression in T cells after high γ-T in vivo supplementation modulates inflammation or other T cell mediated functions...
  12. ncbi request reprint Vitamin E and respiratory infection in the elderly
    Simin Nikbin Meydani
    Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Ann N Y Acad Sci 1031:214-22. 2004
    ....
  13. doi request reprint Diet-induced obesity has a differential effect on adipose tissue and macrophage inflammatory responses of young and old mice
    Dayong Wu
    Nutritional Immunology Laboratory, JM USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Biofactors 39:326-33. 2013
    ..This age-related difference in response to HF diet should be considered when using inflammation status as a marker in investigating adverse health impacts of HF diet and obesity...
  14. ncbi request reprint Effect of hydrogenated and saturated, relative to polyunsaturated, fat on immune and inflammatory responses of adults with moderate hypercholesterolemia
    Sung Nim Han
    Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    J Lipid Res 43:445-52. 2002
    ....