Research Topics
| Lisa M FreemanSummaryAffiliation: Tufts University Country: USA Publications
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Detail Information
Publications
Myocardial concentrations of fatty acids in dogs with dilated cardiomyopathyCaren E Smith
Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA 01536, USA
Am J Vet Res 66:1483-6. 2005..Additional investigation in a larger population is warranted to determine whether this is a primary or secondary effect of the underlying disease and whether alterations in fatty acids may be a target for intervention in dogs with DCM...- Nutritional adequacy of two vegan diets for catsChristina M Gray
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-7010, USA
J Am Vet Med Assoc 225:1670-5. 2004 - Assessment of lipid peroxidation and serum vitamin E concentration in dogs with immune-mediated hemolytic anemiaS Anna Pesillo
Department of Clinical Sciences, School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA
Am J Vet Res 65:1621-4. 2004.... 
Comparison of attitudes between Generation X and Baby Boomer veterinary faculty and residentsLisa M Freeman
Department of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, MA 01536, USA
J Vet Med Educ 36:128-34. 2009..Increased awareness of the importance of balance and rewards for hard work, as well as modification of feedback styles, may be beneficial in teaching and mentoring current and future generations...
Body size and metabolic differences in Maine Coon cats with and without hypertrophic cardiomyopathyLisa M Freeman
Department of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, MA 01536, USA
J Feline Med Surg 15:74-80. 2013..Further studies are warranted to evaluate the effects of early nutrition on the phenotypic expression of HCM...- Development and evaluation of a questionnaire for assessment of health-related quality of life in cats with cardiac diseaseLisa M Freeman
Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA
J Am Vet Med Assoc 240:1188-93. 2012..To develop, validate, and evaluate a questionnaire (Cats' Assessment Tool for Cardiac Health [CATCH] questionnaire) for assessing health-related quality of life in cats with cardiac disease... - Cachexia and sarcopenia: emerging syndromes of importance in dogs and catsL M Freeman
Department of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, MA, USA
J Vet Intern Med 26:3-17. 2012..Greater awareness and earlier diagnosis will help provide practical approaches to managing body weight and lean tissue in dogs and cats, as well as more directed targets for treatment... - Nutrition and cardiomyopathy: lessons from spontaneous animal modelsLisa M Freeman
Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, 200 Westboro Road, North Grafton, MA 01536, USA
Curr Heart Fail Rep 4:84-90. 2007..Dogs and cats with spontaneous cardiomyopathies are an exciting and promising model for studying nutritional modulation of cardiac disease... - The pathophysiology of cardiac cachexiaLisa M Freeman
Department of Clinical Sciences, Tufts University Cummings School of Veterinary Medicine, 200 Westboro Road, North Grafton, MA 01536, USA
Curr Opin Support Palliat Care 3:276-81. 2009..The pathophysiology of cardiac cachexia is complex and multifactorial, but recent studies are providing new information that is helping to clarify the pathophysiology and new targets for treatment... - Body-composition changes in the simian immunodeficiency virus-infected juvenile rhesus macaqueLisa M Freeman
Department of Clinical Sciences, Tufts University School of Veterinary Medicine, North Grafton, Massachusetts 01536, USA
J Infect Dis 189:2010-5. 2004..The purpose of the present study was to measure, as a model of wasting in acquired immunodeficiency syndrome (AIDS), longitudinal body-composition changes in macaques infected with simian immunodeficiency virus (SIV)... - Antioxidant status and biomarkers of oxidative stress in dogs with congestive heart failureLisa M Freeman
Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA
J Vet Intern Med 19:537-41. 2005..The effect of dietary interventions to correct this imbalance in antioxidant defenses warrants further study... - Effects of dietary modification in dogs with early chronic valvular diseaseLisa M Freeman
Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA 01536, USA
J Vet Intern Med 20:1116-26. 2006..The potential benefits of nutritional modification in early canine cardiac disease are not known... - Dietary patterns of dogs with cardiac diseaseLisa M Freeman
Department of Clinical Sciences, Tufts University School of Veterinary Medicine, North Grafton, MA, USA
J Nutr 132:1632S-3S. 2002 - Evaluation of dietary patterns in dogs with cardiac diseaseLisa M Freeman
Department of Clinical Sciences, School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA
J Am Vet Med Assoc 223:1301-5. 2003..Dogs with CHF ate significantly more sodium, compared with dogs with no CHF. CONCLUSIONS AND CLINICAL RELEVANCE: Dietary intake for dogs with cardiac disease is highly variable and often not optimal... - Evaluation of calorie density and feeding directions for commercially available diets designed for weight loss in dogs and catsDeborah E Linder
Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA
J Am Vet Med Assoc 236:74-7. 2010..To determine range of calorie density and feeding directions for commercially available diets designed for weight management in dogs and cats... - Omega-3 fatty acids in Boxer dogs with arrhythmogenic right ventricular cardiomyopathyCaren E Smith
Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, 200 Westboro Road, North Grafton, MA 01536, USA
J Vet Intern Med 21:265-73. 2007..Omega-3 fatty acids have been shown to reduce arrhythmia in animal models and people. These effects have not been studied in dogs with spontaneously occurring arrhythmia... - Disease prevalence among dogs and cats in the United States and Australia and proportions of dogs and cats that receive therapeutic diets or dietary supplementsLisa M Freeman
Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA
J Am Vet Med Assoc 229:531-4. 2006..In addition, the rate of dietary supplement use was lower than that reported for people... - Effects of diet on glucose control in cats with diabetes mellitus treated with twice daily insulin glargineTanya D Hall
Department of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, 200 Westboro Road, North Grafton, MA 01536, United States
J Feline Med Surg 11:125-30. 2009..Frequent monitoring is key to achieving glycemic control in diabetic cats; potential benefits of dietary modification require further evaluation... - Development and evaluation of a questionnaire for assessing health-related quality of life in dogs with cardiac diseaseLisa M Freeman
Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA 01536, USA
J Am Vet Med Assoc 226:1864-8. 2005..CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that the FETCH questionnaire is a valid and reliable method for assessing health-related quality of life in dogs with cardiac disease... - Dietary patterns of cats with cardiac diseaseDanielle S Torin
Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA
J Am Vet Med Assoc 230:862-7. 2007..To determine nutrient intake and dietary patterns in cats with cardiac disease... - Correlations of fatty acid supplementation, aeroallergens, shampoo, and ear cleanser with multiple parameters in pruritic dogsGene H Nesbitt
Department of Clinical Sciences, School of Veterinary Medicine, Tufts University, North Grafton, Massachusetts 01536, USA
J Am Anim Hosp Assoc 40:270-84. 2004..There were no statistically significant differences between individual diets for any of the clinical parameters. The importance of total clinical management in the control of pruritus was demonstrated... - Plasma fatty acid concentrations in Boxers and Doberman PinschersCaren E Smith
Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA
Am J Vet Res 69:195-8. 2008..To compare plasma fatty acid concentrations and the relationships of fatty acids to arrhythmias in Boxers versus Doberman Pinschers... - Use of low molecular weight heparin in cats: 57 cases (1999-2003)Caren E Smith
Department of Clinical Sciences, School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA
J Am Vet Med Assoc 225:1237-41. 2004..CONCLUSIONS AND CLINICAL RELEVANCE: Dalteparin was easily administered by owners and was well tolerated by cats. Whether dalteparin administration can reduce the frequency or severity of arterial thromboembolism is not yet known... - Lymphocyte subpopulations and hematologic variables in dogs with congestive heart failureAndrew E Farabaugh
Tufts University School of Veterinary Medicine, North Grafton, MA, USA
J Vet Intern Med 18:505-9. 2004..CD4+ and CD8+ subpopulations and other blood cell variables are altered in dogs with CHF. Future studies to determine possible clinical implications of these changes are warranted... - Use of glargine and lente insulins in cats with diabetes mellitusKelli E Weaver
Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA
J Vet Intern Med 20:234-8. 2006..The results of the study support the use of once-daily insulin Glargine or twice-daily Lente insulin in combination with a high-protein, low-carbohydrate diet for treatment of feline diabetes mellitus... - Retrospective evaluation of partial parenteral nutrition in dogs and catsDaniel L Chan
Department of Clinical Sciences, Tufts University School of Veterinary Medicine, North Grafton, MA 01536, USA
J Vet Intern Med 16:440-5. 2002..Although PPN seems to be a relatively safe method of providing nutritional support, future studies are warranted to determine its efficacy... - Beneficial effects of omega-3 fatty acids in cardiovascular diseaseLisa M Freeman
Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, USA
J Small Anim Pract 51:462-70. 2010..Additional research is needed to determine optimal indications, doses and formulations for dogs and cats with cardiac disease... - Seizures and severe nutrient deficiencies in a puppy fed a homemade dietDana Hutchinson
Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA
J Am Vet Med Assoc 241:477-83. 2012..Further investigation revealed that the dog was receiving an unbalanced homemade diet... - Population and survival characteristics of cats with hypertrophic cardiomyopathy: 260 cases (1990-1999)John E Rush
Department of Clinical Sciences, School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA
J Am Vet Med Assoc 220:202-7. 2002..CONCLUSIONS AND CLINICAL RELEVANCE: Although overall survival time for cats with HCM was similar to earlier reports, survival times for cats with CHF or ATE were longer than previously reported... - Comparison of pharmacodynamic variables following oral versus transdermal administration of atenolol to healthy catsJohn M MacGregor
Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA
Am J Vet Res 69:39-44. 2008..To describe the disposition of and pharmacodynamic response to atenolol when administered as a novel transdermal gel formulation to healthy cats... - Comparisons of morphometric measurements and serum insulin-like growth factor concentration in healthy cats and cats with hypertrophic cardiomyopathyVicky K Yang
Department of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, MA 01536, USA
Am J Vet Res 69:1061-6. 2008.... - Evaluation of acute congestive heart failure in dogs and cats: 145 cases (2007-2008)Caroline M Goutal
Department of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, MA 01536, USA
J Vet Emerg Crit Care (San Antonio) 20:330-7. 2010..To characterize the clinical presentation, management, and in-hospital outcomes of dogs and cats diagnosed with acute congestive heart failure (CHF)... - Evaluation of vehicular trauma in dogs: 239 cases (January-December 2001)Elizabeth M Streeter
Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA
J Am Vet Med Assoc 235:405-8. 2009..To describe a population of dogs with vehicular trauma and to determine whether age, type and severity of injury, or preexisting disease were associated with outcome... - Prospective evaluation of tissue plasminogen activator in 11 cats with arterial thromboembolismKristin M Welch
Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, 200 Westboro Road, North Grafton, MA, USA
J Feline Med Surg 12:122-8. 2010..While signs compatible with thrombolysis were noted in many cats following tPA administration, a high rate of side effects and low rate of hospital discharge were noted in this study... - Serum nitrate and nitrite in dogs with spontaneous cardiac diseaseArmelle M de Laforcade
Department of Clinical Sciences, Tufts University School of Veterinary Medicine, North Grafton, MA 01536, USA
J Vet Intern Med 17:315-8. 2003.... - Association of expiratory airway dysfunction with marked obesity in healthy adult dogsJonathan F Bach
Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA
Am J Vet Res 68:670-5. 2007..To evaluate the effects of obesity on pulmonary function in healthy adult dogs... - Hemostatic changes in dogs with naturally occurring sepsisArmelle M de Laforcade
Department of Clinical Sciences at Tufts University School of Veterinary Medicine, North Grafton, MA 01536, USA
J Vet Intern Med 17:674-9. 2003..On the basis of these results, further investigation of the role of AT and PC in canine sepsis is warranted... - Biochemical analysis of pericardial fluid and whole blood in dogs with pericardial effusionArmelle M de Laforcade
Department of Clinical Sciences, Tufts University School of Veterinary Medicine, 200 Westboro Road, North Grafton, MA 01536, USA
J Vet Intern Med 19:833-6. 2005..Although differences between variables in dogs with neoplastic and nonneoplastic pericardial effusion were documented, clinical relevance is likely limited by the degree of overlap between the 2 groups... - C-reactive protein concentration in dogs with chronic valvular diseaseJohn E Rush
Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA 01536, USA
J Vet Intern Med 20:635-9. 2006..The results of this study suggest that increased concentration of C-reactive protein is found in dogs with chronic valvular disease... - Cholecystoenterostomy for treatment of extrahepatic biliary tract obstruction in cats: 22 cases (1994-2003)Nicole J Buote
Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA 01536, USA
J Am Vet Med Assoc 228:1376-82. 2006..However, the overall prognosis for cats with EHBTO undergoing cholecystoenterostomy must be considered guarded to poor, and the incidence of perioperative complications is high... - Intestinal permeability and absorption in dogs with traumatic injuryElizabeth M Streeter
Department of Clinical Sciences, Tufts University School of Veterinary Medicine, North Grafton, MA 01536, USA
J Vet Intern Med 16:669-73. 2002..Results of this study support the hypothesis that intestinal permeability and absorption are altered in dogs with traumatic injury... - Effect of n-3 fatty acid ratio and dose on clinical manifestations, plasma fatty acids and inflammatory mediators in dogs with pruritusGene H Nesbitt
Tufts University School of Veterinary Medicine, North Grafton, Massachusetts, USA
Vet Dermatol 14:67-74. 2003..In this clinical trial, which controlled dietary intake of fatty acids, n-3 fatty acid supplementation did not appear to have an added benefit on clinical signs over thorough clinical management... - Packed red blood cell transfusions in dogs with gastrointestinal hemorrhage: 55 cases (1999-2001)Jennifer E Waldrop
Department of Clinical Sciences, School of Veterinary Medicine, Tufts University, North Grafton, Massachusetts 01536, USA
J Am Anim Hosp Assoc 39:523-7. 2003..Dogs with IMT received more transfusions of PRBC than nonIMT dogs (P<0.03) and received a significantly larger total volume of PRBC (P<0.01) during hospitalization... - Effect of dietary soy on serum thyroid hormone concentrations in healthy adult catsHeidi L White
Department of Clinical Sciences, School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA
Am J Vet Res 65:586-91. 2004..Increase in T4 concentration relative to T3 concentration may result from inhibition of 5'-iodothyronine deiodinase or enhanced T3 clearance. Soy is a common dietary component that increases serum T4 concentration in cats... - Extensive small bowel resection in dogs and cats: 20 cases (1998-2004)Stephanie C Gorman
Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA 01536, USA
J Am Vet Med Assoc 228:403-7. 2006..The amount of intestine resected was not associated with outcome. These data may be useful in providing prognostic information in cases of extensive small intestinal resection... - Composition, disintegrative properties, and labeling compliance of commercially available taurine and carnitine dietary productsRebecca R Bragg
Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA 01536, USA
J Am Vet Med Assoc 234:209-13. 2009..To test the quality, disintegration properties, and compliance with labeling regulations for representative commercially available taurine and carnitine dietary products... - Chronic hepatitis in Labrador Retrievers: clinical presentation and prognostic factorsJulia L Shih
Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA, USA
J Vet Intern Med 21:33-9. 2007..An increased incidence of chronic hepatitis has been reported in Labrador Retrievers... - Theoretical evaluation of risk for nutritional deficiency with caloric restriction in dogsDeborah E Linder
Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, USA
Vet Q 32:123-9. 2012..Risk of nutrient deficiency in dogs during caloric restriction is not currently known, while obesity is a growing concern... - Assessment of methods of evaluating sarcopenia in old dogsDana Hutchinson
Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536
Am J Vet Res 73:1794-800. 2012..A better understanding of underlying mechanisms of sarcopenia as well as methods for slowing progression is needed... - Use of a flow-mediated vasodilation technique to assess endothelial function in dogsGary D Puglia
Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA
Am J Vet Res 67:1533-40. 2006.... - Identification and concentration of soy isoflavones in commercial cat foodsMichael H Court
Department of Pharmacology and Experimental Therapeutics, School of Medicine, Tufts University, Boston, MA 02111, USA
Am J Vet Res 63:181-5. 2002..Predictors of isoflavone content included ingredient labeling, food type, and food cost. Soy isoflavones in some commercial cat foods were detected in amounts predicted to have a biological effect... - Nutrition in critical illnessDaniel L Chan
Department of Veterinary Clinical Sciences, The Royal Veterinary College, University of London, Hawkshead Lane Medicine, North Mymms, Hertfordshire AL97TA, United Kingdom
Vet Clin North Am Small Anim Pract 36:1225-41, v-vi. 2006.... - Pet feeding practices of dog and cat owners in the United States and AustraliaDorothy P Laflamme
, Checkerboard Sq, St Louis, MO 63164, USA
J Am Vet Med Assoc 232:687-94. 2008
Research Grants
- Interdisciplinary Research Training for VeterinariansLisa Freeman; Fiscal Year: 2007..These evaluations, continued refinement, and the commitment of the program faculty will help to ensure that this becomes a self-sustaining program. ..