A M Cuervo

Summary

Affiliation: Tufts University
Country: USA

Publications

  1. ncbi Direct lysosomal uptake of alpha 2-microglobulin contributes to chemically induced nephropathy
    A M Cuervo
    Department of Physiology, Tufts University School of Medicine, Boston, Massachusetts, USA
    Kidney Int 55:529-45. 1999
  2. ncbi Selective degradation of annexins by chaperone-mediated autophagy
    A M Cuervo
    Department of Physiology, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    J Biol Chem 275:33329-35. 2000
  3. ncbi Unique properties of lamp2a compared to other lamp2 isoforms
    A M Cuervo
    Department of Physiology, Tufts University School of Medicine, Boston, MA, USA
    J Cell Sci 113:4441-50. 2000
  4. pmc Chaperone-mediated autophagy
    S Kaushik
    Department of Anatomy and Structural Biology, Marion Bessin Liver Research Center, Albert Einstein College of Medicine, New York, NY, USA
    Methods Mol Biol 445:227-44. 2008
  5. ncbi LAPTM5: a novel lysosomal-associated multispanning membrane protein preferentially expressed in hematopoietic cells
    C N Adra
    Division of Hematology Oncology, Harvard Medical School, Boston, Massachusetts, 02215, USA
    Genomics 35:328-37. 1996
  6. pmc Autophagy as a cell-repair mechanism: activation of chaperone-mediated autophagy during oxidative stress
    S Kaushik
    Department of Anatomy and Structural Biology, Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Ullmann Building room 611D, Bronx, NY 10461, USA
    Mol Aspects Med 27:444-54. 2006

Collaborators

  • J A Barnes
  • S Kaushik
  • C N Adra
  • J D Rowley
  • J M Lelias
  • S Zhu
  • H Kobayashi
  • T Horiuchi
  • J C Guillemot
  • J L Ko
  • B Lim

Detail Information

Publications6

  1. ncbi Direct lysosomal uptake of alpha 2-microglobulin contributes to chemically induced nephropathy
    A M Cuervo
    Department of Physiology, Tufts University School of Medicine, Boston, Massachusetts, USA
    Kidney Int 55:529-45. 1999
    ..Because a portion of alpha 2 mu resides in the cytosol of kidney cells, we decided to analyze whether this cytosolic form also contributes to the abnormal lysosomal accumulation of alpha 2 mu after exposure to chemicals...
  2. ncbi Selective degradation of annexins by chaperone-mediated autophagy
    A M Cuervo
    Department of Physiology, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    J Biol Chem 275:33329-35. 2000
    ..These results provide striking evidence for the importance of KFERQ motifs in substrates of chaperone-mediated autophagy...
  3. ncbi Unique properties of lamp2a compared to other lamp2 isoforms
    A M Cuervo
    Department of Physiology, Tufts University School of Medicine, Boston, MA, USA
    J Cell Sci 113:4441-50. 2000
    ..These characteristics may be important for lamp2a to act as a receptor for chaperone-mediated autophagy...
  4. pmc Chaperone-mediated autophagy
    S Kaushik
    Department of Anatomy and Structural Biology, Marion Bessin Liver Research Center, Albert Einstein College of Medicine, New York, NY, USA
    Methods Mol Biol 445:227-44. 2008
    ..However, the most unequivocal method to measure CMA is by directly tracking the translocation of substrate proteins into isolated lysosomes...
  5. ncbi LAPTM5: a novel lysosomal-associated multispanning membrane protein preferentially expressed in hematopoietic cells
    C N Adra
    Division of Hematology Oncology, Harvard Medical School, Boston, Massachusetts, 02215, USA
    Genomics 35:328-37. 1996
    ..The expression pattern of the gene together with preliminary evidence that the protein interacts with ubiquitin indicates that the protein may have a special functional role during embryogenesis and in adult hematopoietic cells...
  6. pmc Autophagy as a cell-repair mechanism: activation of chaperone-mediated autophagy during oxidative stress
    S Kaushik
    Department of Anatomy and Structural Biology, Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Ullmann Building room 611D, Bronx, NY 10461, USA
    Mol Aspects Med 27:444-54. 2006
    ..The consequences of an impairment in CMA activity, observed during aging and in some age-related disorders, are also discussed...