Bartolome Celli

Summary

Affiliation: Tufts University
Country: USA

Publications

  1. ncbi request reprint Cough and phlegm are important predictors of health status in smokers without COPD
    Yvonne F Heijdra
    Pulmonary Department, University Medical Center, St Radboud, Nijmegen, The Netherlands
    Chest 121:1427-33. 2002
  2. ncbi request reprint Change in the BODE index reflects disease modification in COPD: lessons from lung volume reduction surgery
    Bartolome R Celli
    Chest 129:835-6. 2006
  3. pmc Inflammatory and repair serum biomarker pattern: association to clinical outcomes in COPD
    Victor Pinto-Plata
    Pulmonary Critical Care Medicine Division, St Elizabeth s Medical Center, Boston, MA 02115, USA
    Respir Res 13:71. 2012
  4. pmc Longitudinal inspiratory capacity changes in chronic obstructive pulmonary disease
    Bartolome R Celli
    Pulmonary Division, Brigham and Women s Hospital, Boston, MA, USA
    Respir Res 13:66. 2012
  5. pmc Adverse health consequences in COPD patients with rapid decline in FEV1--evidence from the UPLIFT trial
    Steven Kesten
    Boehringer Ingelheim Pharmaceuticals, Ridgefield, Connecticut, USA
    Respir Res 12:129. 2011
  6. pmc Health status in the TORCH study of COPD: treatment efficacy and other determinants of change
    Paul W Jones
    Department of Cardiac and Vascular Sciences, St George s Hospital, University of London, London, UK
    Respir Res 12:71. 2011
  7. pmc Markers of exacerbation severity in chronic obstructive pulmonary disease
    Luigi G Franciosi
    Leiden Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands
    Respir Res 7:74. 2006
  8. pmc Gender and respiratory factors associated with dyspnea in chronic obstructive pulmonary disease
    Juan P de Torres
    Respiratory Research Unit, Hospital Nuestra Sra de Candelaria, Tenerife, Spain
    Respir Res 8:18. 2007
  9. pmc Acute bronchodilator responsiveness and health outcomes in COPD patients in the UPLIFT trial
    Nicola A Hanania
    Section of Pulmonary, Critical Care and Sleep Medicine, Baylor College of Medicine, Houston, TX, USA
    Respir Res 12:6. 2011
  10. pmc Characterisation of COPD heterogeneity in the ECLIPSE cohort
    Alvar Agusti
    Thorax Institute, Hospital Clinic, IDIBAPS, Universitat de Barcelona, Spain
    Respir Res 11:122. 2010

Detail Information

Publications67

  1. ncbi request reprint Cough and phlegm are important predictors of health status in smokers without COPD
    Yvonne F Heijdra
    Pulmonary Department, University Medical Center, St Radboud, Nijmegen, The Netherlands
    Chest 121:1427-33. 2002
    ..Therefore, the aim of the study was to explore whether the differences in quality of life between smokers and ex-smokers could be explained by cough and phlegm, differences in pulmonary function tests, or exercise capacity...
  2. ncbi request reprint Change in the BODE index reflects disease modification in COPD: lessons from lung volume reduction surgery
    Bartolome R Celli
    Chest 129:835-6. 2006
  3. pmc Inflammatory and repair serum biomarker pattern: association to clinical outcomes in COPD
    Victor Pinto-Plata
    Pulmonary Critical Care Medicine Division, St Elizabeth s Medical Center, Boston, MA 02115, USA
    Respir Res 13:71. 2012
    ..The relationship between serum biomarkers and clinical expressions of COPD is limited. We planned to further describe this association using markers of inflammation and injury and repair...
  4. pmc Longitudinal inspiratory capacity changes in chronic obstructive pulmonary disease
    Bartolome R Celli
    Pulmonary Division, Brigham and Women s Hospital, Boston, MA, USA
    Respir Res 13:66. 2012
    ..The changes in inspiratory capacity (IC) over time in chronic obstructive pulmonary disease (COPD) patients are unknown. The Understanding Potential Long-term Impacts on Function with Tiotropium (UPLIFT®) trial included IC measurements...
  5. pmc Adverse health consequences in COPD patients with rapid decline in FEV1--evidence from the UPLIFT trial
    Steven Kesten
    Boehringer Ingelheim Pharmaceuticals, Ridgefield, Connecticut, USA
    Respir Res 12:129. 2011
    ..The rate of decline in forced expiratory volume in 1 second (FEV1) is representative of the natural history of COPD. Sparse information exists regarding the associations between the magnitude of annualised loss of FEV1 with other endpoints...
  6. pmc Health status in the TORCH study of COPD: treatment efficacy and other determinants of change
    Paul W Jones
    Department of Cardiac and Vascular Sciences, St George s Hospital, University of London, London, UK
    Respir Res 12:71. 2011
    ..Little is known about factors that determine health status decline in clinical trials of COPD...
  7. pmc Markers of exacerbation severity in chronic obstructive pulmonary disease
    Luigi G Franciosi
    Leiden Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands
    Respir Res 7:74. 2006
    ..In an attempt to find the best surrogates for exacerbations, we have reviewed the literature to identify which of these markers change in a consistent manner with the severity of the exacerbation event...
  8. pmc Gender and respiratory factors associated with dyspnea in chronic obstructive pulmonary disease
    Juan P de Torres
    Respiratory Research Unit, Hospital Nuestra Sra de Candelaria, Tenerife, Spain
    Respir Res 8:18. 2007
    ..We had shown that COPD women expressed more dyspnea than men for the same degree of airway obstruction...
  9. pmc Acute bronchodilator responsiveness and health outcomes in COPD patients in the UPLIFT trial
    Nicola A Hanania
    Section of Pulmonary, Critical Care and Sleep Medicine, Baylor College of Medicine, Houston, TX, USA
    Respir Res 12:6. 2011
    ..Debate continues as to whether acute bronchodilator responsiveness (BDR) predicts long-term outcomes in COPD. Furthermore, there is no consensus on a threshold for BDR...
  10. pmc Characterisation of COPD heterogeneity in the ECLIPSE cohort
    Alvar Agusti
    Thorax Institute, Hospital Clinic, IDIBAPS, Universitat de Barcelona, Spain
    Respir Res 11:122. 2010
    ..Chronic obstructive pulmonary disease (COPD) is a complex condition with pulmonary and extra-pulmonary manifestations. This study describes the heterogeneity of COPD in a large and well characterised and controlled COPD cohort (ECLIPSE)...
  11. pmc Gender associated differences in determinants of quality of life in patients with COPD: a case series study
    Juan P de Torres
    Respiratory Research Unit, Hospital Nuestra Sra de Candelaria, Tenerife, Spain
    Health Qual Life Outcomes 4:72. 2006
    ..Quality of Life (QoL) has become an important outcome in COPD patients. The aim of our study was to explore factors contributing to gender differences in Quality of Life of COPD patients...
  12. pmc Venous admixture in COPD: pathophysiology and therapeutic approaches
    Christopher B Cooper
    David Geffen School of Medicine, University of California, Los Angeles, California 90095 1690, USA
    COPD 5:376-81. 2008
    ..This approach to treatment could have significant impact for patients with COPD but should also benefit any patient with chronic hypoxemia that impairs exercise performance...
  13. doi request reprint Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease: results from the TORCH study
    Bartolome R Celli
    Tufts University School of Medicine, Pulmonary and Critical Care Division, Caritas St Elizabeth s Medical Center, Boston, MA 02135 2997, USA
    Am J Respir Crit Care Med 178:332-8. 2008
    ..Chronic obstructive pulmonary disease (COPD) is characterized by an accelerated decline in lung function. No drug has been shown conclusively to reduce this decline...
  14. ncbi request reprint Update on the management of COPD
    Bartolome R Celli
    Pulmonary and Critical Care Medicine, Caritas St Elizabeth s Medical Center, Boston, MA 02135 2997, USA
    Chest 133:1451-62. 2008
    ..Ultimately, the advent of newer and more effective therapies will lead to a decline in the contribution of this disease to poor world health...
  15. ncbi request reprint Novel concepts in the pharmacotherapy of chronic obstructive pulmonary disease
    Bartolome R Celli
    Division of Pulmonary and Critical Care Medicine, Caritas St Elizabeth s Medical Center, Boston, Stany Zjednoczone
    Pneumonol Alergol Pol 77:82-90. 2009
    ..Ultimately, the advent of newer and more effective therapies will lead to a decline in the contribution of this disease to poor world health...
  16. ncbi request reprint Future perspectives in COPD
    Bartolome Celli
    Caritas St Elizabeth s Medical Center, Department of Medicine, Tufts University, Boston, USA
    Respir Med 99:S41-8. 2005
    ..Many questions remain to be answered, but a comprehensive approach is now considered essential to the life-long management of COPD, and will undoubtedly reduce the considerable socio-economic burden of COPD...
  17. ncbi request reprint Roger s. Mitchell lecture. Chronic obstructive pulmonary disease phenotypes and their clinical relevance
    Bartolome R Celli
    Pulmonary and Critical Care Services, Caritas St Elizabeth s Medical Center, 736 Cambridge Street, Boston, MA 02135, USA
    Proc Am Thorac Soc 3:461-5. 2006
    ..The hope is that, coupled with primary and secondary prevention, we can reverse the current epidemic and we can improve the well-being of patients affected by COPD...
  18. doi request reprint Mortality in the 4-year trial of tiotropium (UPLIFT) in patients with chronic obstructive pulmonary disease
    Bartolome Celli
    Brigham and Women s Hospital and St Elizabeth s Medical Center, Boston, MA 02115, USA
    Am J Respir Crit Care Med 180:948-55. 2009
    ..Mortality and its causes was a secondary endpoint in UPLIFT...
  19. doi request reprint Predictors of mortality in COPD
    Bartolome R Celli
    Tufts University, St Elizabeth s Medical Center, 736 Cambridge St, Boston, MA 02135, USA
    Respir Med 104:773-9. 2010
    ..This article reviews these predictors of mortality in COPD...
  20. doi request reprint Sex differences in mortality and clinical expressions of patients with chronic obstructive pulmonary disease. The TORCH experience
    Bartolome Celli
    Pulmonary and Critical Care Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    Am J Respir Crit Care Med 183:317-22. 2011
    ..Objectives: Determine sex differences in survival, causes of death, and patient-centered outcomes in the 3-year Toward a Revolution in COPD Health (TORCH) study...
  21. ncbi request reprint The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease
    Bartolome R Celli
    COPD Center at St Elizabeth s Medical Center, Tufts University School of Medicine, Boston, MA 02135, USA
    N Engl J Med 350:1005-12. 2004
    ..We hypothesized that a multidimensional grading system that assessed the respiratory and systemic expressions of COPD would better categorize and predict outcome in these patients...
  22. doi request reprint Bronchodilator responsiveness and onset of effect with budesonide/formoterol pMDI in COPD
    Bartolome R Celli
    Harvard University, Brigham and Women s Hospital, Pulmonary and Critical Care Medicine, Boston, MA 02115, USA
    Respir Med 105:1176-88. 2011
    ..We also evaluated the speed of onset of bronchodilation...
  23. ncbi request reprint A 62-year-old woman with chronic obstructive pulmonary disease
    Bartolome R Celli
    Tufts University, USA
    JAMA 290:2721-9. 2003
  24. pmc Profiling serum biomarkers in patients with COPD: associations with clinical parameters
    Victor Pinto-Plata
    Caritas St Elizabeth s Medical Center, 736 Cambridge Street, Boston, Massachusetts 02135, USA
    Thorax 62:595-601. 2007
    ..A systematic analysis was undertaken of multiple protein analytes in the serum of well characterised patients with COPD and matched controls using novel protein microarray platform (PMP) technology...
  25. doi request reprint Cardiovascular safety of tiotropium in patients with COPD
    Bartolome Celli
    Carita St Elizabeth s Medical Center, Boston, MA, USA
    Chest 137:20-30. 2010
    ..The clinical trial safety database for tiotropium has been augmented with a 4-year trial in patients with COPD, which provides an opportunity to better evaluate the cardiovascular (CV) profile of tiotropium...
  26. ncbi request reprint Improvement in resting inspiratory capacity and hyperinflation with tiotropium in COPD patients with increased static lung volumes
    Bartolome Celli
    Pulmonary and Critical Care Division, St Elizabeth s Medical Center, Boston, MA 02135, USA
    Chest 124:1743-8. 2003
    ..We sought to evaluate changes in resting IC and lung volumes after long-term administration of tiotropium...
  27. doi request reprint Effect of tiotropium in men and women with COPD: results of the 4-year UPLIFT trial
    Donald Tashkin
    Department of Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095 1690, USA
    Respir Med 104:1495-504. 2010
    ..Gender differences may occur in many chronic diseases. We have examined the influence of gender in chronic obstructive pulmonary disease (COPD) on long-term responses to tiotropium...
  28. pmc Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease
    Deog Kyeom Kim
    Channing Division of Network Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Am J Respir Crit Care Med 186:1238-47. 2012
    ..A genome-wide association study (GWAS) for circulating chronic obstructive pulmonary disease (COPD) biomarkers could identify genetic determinants of biomarker levels and COPD susceptibility...
  29. ncbi request reprint Biological lung volume reduction: a new bronchoscopic therapy for advanced emphysema
    John Reilly
    Brigham and Women s Hospital, Pulmonary Critical Care Medicine, 75 Francis St, Boston, MA 02115 6110, USA
    Chest 131:1108-13. 2007
    ..This report summarizes the initial clinical experience including a 3-month follow-up using this technique in humans...
  30. doi request reprint Resting handgrip force and impaired cardiac function at rest and during exercise in COPD patients
    Felipe Cortopassi
    Division of Pulmonary, St Elizabeth s Medical Center, Tufts University School of Medicine, Boston, MA 02135, USA
    Respir Med 105:748-54. 2011
    ..Cardiac function measured as the oxygen pulse (O(2) pulse) is impaired during exercise (CPET) in patients with COPD. We investigated the relationship between handgrip force and O(2) pulse in COPD and controls...
  31. doi request reprint Cardiopulmonary exercise testing: relevant but underused
    Daniel E Forman
    Division of Cardiovascular Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Postgrad Med 122:68-86. 2010
    ..In this article, we provide an overview of CPX principles and testing logistics, as well as some of the clinical contexts in which it can enhance patient care...
  32. ncbi request reprint Proposal for a multidimensional staging system for chronic obstructive pulmonary disease
    Bartolome R Celli
    Department of Pulmonary and Critical Care Medicine, Tufts University, Boston, MA 02135, USA
    Respir Med 99:1546-54. 2005
    ..Although the staging boundaries were based on existing literature, they have proven useful in predicting survival. We conclude that a multidimensional grading system is useful to assess the impact of COPD...
  33. pmc Characterizing functional lung heterogeneity in COPD using reference equations for CT scan-measured lobar volumes
    Carolyn E Come
    Pulmonary and Critical Care Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Chest 143:1607-17. 2013
    ..Using COPDGene data, we developed reference equations for lobar volumes at maximal inflation (total lung capacity [TLC]) and relaxed exhalation (approximating functional residual capacity [FRC])...
  34. doi request reprint Comorbidities and risk of mortality in patients with chronic obstructive pulmonary disease
    Miguel Divo
    Pulmonary and Critical Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Respir Crit Care Med 186:155-61. 2012
    ..Patients with chronic obstructive pulmonary disease (COPD) are afflicted by comorbidities. Few studies have prospectively evaluated COPD comorbidities and mortality risk...
  35. ncbi request reprint Power of outcome measurements to detect clinically significant changes in pulmonary rehabilitation of patients with COPD
    Juan Pablo de Torres
    Pulmonary and Critical Care Division, St Elizabeth s Medical Center, Boston 02135 2997, USA
    Chest 121:1092-8. 2002
    ..We designed this study to investigate the capacity of several of the most frequently used outcome measurements to detect changes after PR in a population of patients with severe COPD who qualified for lung volume reduction surgery...
  36. ncbi request reprint Differences in cardiopulmonary exercise test results by American Thoracic Society/European Respiratory Society-Global Initiative for Chronic Obstructive Lung Disease stage categories and gender
    Victor M Pinto-Plata
    Division of Pulmonary, Critical Care and Sleep Medicine, Caritas St Elizabeth s Medical Center, Tufts University School of Medicine, 736 Cambridge St, Boston, MA 02135, USA
    Chest 132:1204-11. 2007
    ..We hypothesized that exercise performance measured by cardiopulmonary exercise test (CPET) results should decline significantly with each disease stage, independent of gender...
  37. ncbi request reprint The 6-min walk distance, peak oxygen uptake, and mortality in COPD
    Claudia G Cote
    Pulmonary and Critical Care Medicine, Bay Pines VA Health Care System, 10, 000 Bay Pines Blvd, Bay Pines, FL 33744, USA
    Chest 132:1778-85. 2007
    ..993 to 0.999; p < 0.01) had a stronger association than the peak Vo2 (HR, 0.971; 95% CI, 0.959 to 1.000; p = 0.050) with mortality. This study shows the 6MWD is as good predictor of mortality as the peak Vo2 in patients with COPD...
  38. doi request reprint Predictors of Survival in COPD: more than just the FEV1
    Bartolome R Celli
    Caritas St Elizabeth s Medical Center, Boston, MA, USA
    Respir Med 102:S27-35. 2008
    ....
  39. ncbi request reprint Systemic cytokines, clinical and physiological changes in patients hospitalized for exacerbation of COPD
    Victor M Pinto-Plata
    Division of Pulmonary and Critical Care Medicine, St Elizabeth s Medical Center, Tufts University School of Medicine, Boston, MA, USA
    Chest 131:37-43. 2007
    ..Systemic inflammation in patients with COPD may worsen during exacerbations, but there is limited information relating levels of systemic inflammatory markers with symptoms and physiologic changes during an exacerbation..
  40. pmc A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13
    Michael H Cho
    Channing Laboratory, Brigham and Women s Hospital, Boston, MA 02115, USA
    Hum Mol Genet 21:947-57. 2012
    ..08 and 0.04) and severe (GOLD 3&4) COPD (P = 0.09 and 0.017). This region includes RAB4B, EGLN2, MIA and CYP2A6, and has previously been identified in association with cigarette smoking behavior...
  41. pmc Genome-wide association study of smoking behaviours in patients with COPD
    Mateusz Siedlinski
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Thorax 66:894-902. 2011
    ..Associations of CHRNA3/CHRNA5 and CYP2A6 loci with CPD and DBH with smoking cessation are also likely of importance in the smoking behaviours of patients with COPD...
  42. ncbi request reprint Gene expression profiling of human lung tissue from smokers with severe emphysema
    Avrum Spira
    The Pulmonary Center and Department of Medicine, Boston University School of Medicine, 715 Albany Street, R304, Boston, MA 02118, USA
    Am J Respir Cell Mol Biol 31:601-10. 2004
    ....
  43. ncbi request reprint Use of proteomic patterns of serum biomarkers in patients with chronic obstructive pulmonary disease: correlation with clinical parameters
    Victor Pinto-Plata
    Pulmonary Critical Care Medicine, Caritas St Elizabeth s Medical Center, 736 Cambridge Street, Boston, MA 02135
    Proc Am Thorac Soc 3:465-6. 2006
  44. ncbi request reprint Chronic obstructive pulmonary disease: from unjustified nihilism to evidence-based optimism
    Bartolome R Celli
    Department of Medicine, Tufts University
    Proc Am Thorac Soc 3:58-65. 2006
    ..The advent of newer and more effective therapies will lead to a decline in the contribution of this disease to poor world health...
  45. doi request reprint Lung volume reduction therapies for advanced emphysema: an update
    Robert L Berger
    Division of Cardiothoracic Surgery, Beth Israel Deaconess Medical Center, Deaconess, Boston, MA 02215, USA
    Chest 138:407-17. 2010
    ..Although there is promise of limited therapeutic influence, the available information is not sufficient to recommend use of bronchoscopic strategies for treating emphysema...
  46. pmc Longitudinal change in the BODE index predicts mortality in severe emphysema
    Fernando J Martinez
    Division of Pulmonary and Critical Care Medicine, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0360, USA
    Am J Respir Crit Care Med 178:491-9. 2008
    ..We hypothesized that decrease in a modified BODE (mBODE) would predict survival in National Emphysema Treatment Trial (NETT) patients...
  47. ncbi request reprint Airway obstruction in never smokers: results from the Third National Health and Nutrition Examination Survey
    Bartolome R Celli
    Caritas St Elizabeth s Medical Center, Tufts University Medical School, Boston, Mass, USA
    Am J Med 118:1364-72. 2005
    ..COPD is rarely considered in persons with no smoking history except in the context of another exposure. Accordingly, the disease has not been well characterized in these "never smokers."..
  48. ncbi request reprint Pulmonary rehabilitation
    Bartolome R Celli
    St Elizabeth s Medical Center, Tufts University, Boston, MA, USA
    Isr Med Assoc J 5:443-8. 2003
  49. ncbi request reprint Tracheobronchitis caused by methicillin-resistant Staphylococcus aureus as a cause of chronic wheezing in a non-ventilated adult patient with tracheobronchomalacia
    Theodoros Kelesidis
    Department of Medicine, Caritas St Elizabeth s Medical Center, Tufts University School of Medicine, Boston, MA 02135, USA
    Respiration 80:148-56. 2010
    ..Physicians should be aware of the diagnosis of tracheomalacia in adults, which can masquerade as persistent asthma and may be associated with the development of serious infections including MRSA tracheobronchitis...
  50. ncbi request reprint Deep breath reversal and exponential return of methacholine-induced obstruction in asthmatic and nonasthmatic subjects
    Andrew C Jackson
    Biomedical Engineering Dept, Boston Univ, 44 Cummington St, Boston, MA 02215, USA
    J Appl Physiol (1985) 96:137-42. 2004
    ..19 +/- 4.95 and 7.14 +/- 3.56 cmH2O.l-1.s, respectively). The monoexponential recovery suggests a first-order process such as airway wall-parenchymal tissue interdependence or renewed constriction of airway smooth muscle...
  51. ncbi request reprint Discrepancy in the use of confirmatory tests in patients hospitalized with the diagnosis of chronic obstructive pulmonary disease or congestive heart failure
    Mahendra Damarla
    Division of Pulmonary and Critical Care Medicine, Caritas St Elizabeth s Medical Center, Boston, Massachusetts 02135, USA
    Respir Care 51:1120-4. 2006
    ....
  52. pmc Comorbidities, patient knowledge, and disease management in a national sample of patients with COPD
    R Graham Barr
    Division of General Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Am J Med 122:348-55. 2009
    ..We evaluated the prevalence of these comorbid conditions and compared testing, patient knowledge, and management in a national sample of patients with COPD...
  53. ncbi request reprint Chronic respiratory failure after lung resection: the role of pulmonary rehabilitation
    Bartolome R Celli
    Division of Pulmonary and Critical Care Medicine, Caritas St Elizabeth s Medical Center, Seton 3 Pulmonary, 736 Cambridge Street, Brighton, MA 02135, USA
    Thorac Surg Clin 14:417-28. 2004
    ..Currently, pulmonary rehabilitation should be made available to all patients with symptomatic respiratory disease and be an integral part of any program considering high-risk surgery...
  54. ncbi request reprint Physician and patient perceptions in COPD: the COPD Resource Network Needs Assessment Survey
    R Graham Barr
    Division of General Medicine, Department of Medicine, College of Physicians and Surgeons, Mailman School of Public Health, Columbia University, New York, NY, USA
    Am J Med 118:1415. 2005
    ..National data are lacking on patient and physician perceptions of and patterns of care for COPD...
  55. ncbi request reprint Muscle strength and exercise kinetics in COPD patients with a normal fat-free mass index are comparable to control subjects
    Yvonne F Heijdra
    Pulmonary Department, University Medical Center St Radboud, Nijmegen, The Netherlands
    Chest 124:75-82. 2003
    ....
  56. ncbi request reprint Predicting mortality in chronic obstructive pulmonary disease: chasing the "Holy Grail"
    Bartolome R Celli
    Am J Respir Crit Care Med 173:1298-9. 2006
  57. ncbi request reprint Markers of disease severity in chronic obstructive pulmonary disease
    Luigi G Franciosi
    Gorlaeus Laboratories, Leiden Amsterdam Center for Drug Research, Leiden University, The Netherlands
    Pulm Pharmacol Ther 19:189-99. 2006
    ....
  58. ncbi request reprint C-reactive protein levels and survival in patients with moderate to very severe COPD
    Juan P de Torres
    Respiratory Research Unit, Hospital Ntra Sra de Candelaria, Canary Islands, Tenerife, Spain
    Chest 133:1336-43. 2008
    ..In epidemiologic studies, CRP level is associated with all-cause mortality in patients with mild-to-moderate disease...
  59. ncbi request reprint What is the best pharmacological treatment to prevent exacerbation of chronic obstructive pulmonary disease?
    Bartolome R Celli
    Pol Arch Med Wewn 118:172-4. 2008
  60. doi request reprint Distance and oxygen desaturation during the 6-min walk test as predictors of long-term mortality in patients with COPD
    Ciro Casanova
    Pulmonary Department, Hospital La Candelaria, Carretera del Rosario n degrees 145, 38010 Santa Cruz de Tenerife, Spain
    Chest 134:746-52. 2008
    ..Little is known about its prognostic value in patients with a wider range of COPD severity, living in different countries, and the potential additional impact of oxygen desaturation measured during the test...
  61. ncbi request reprint Gender and COPD in patients attending a pulmonary clinic
    Juan P de Torres
    Respiratory Research Unit, Hospital Nuestra Sra de Candelaria, Tenerife, Spain
    Chest 128:2012-6. 2005
    ..To compare gender differences in the clinical expression of COPD patients attending a pulmonary clinic...
  62. ncbi request reprint Pulmonary rehabilitation improves depression, anxiety, dyspnea and health status in patients with COPD
    Hildegarde Paz-Díaz
    Pulmonary Division, Hospital Universitario de Caracas, Universidad Central de Venezuela, Caracas, Venezuela
    Am J Phys Med Rehabil 86:30-6. 2007
    ..To determine the impact of an 8-wk program of comprehensive pulmonary rehabilitation on depression, anxiety, dyspnea, and health-related quality of life in patients with chronic obstructive pulmonary disease (COPD)...
  63. ncbi request reprint Lung volume reduction surgery vs medical treatment: for patients with advanced emphysema
    John D Miller
    McMaster University, Hamilton Ontarion, Canada
    Chest 127:1166-77. 2005
    ..To contribute to the knowledge on the therapeutic value of lung volume reduction surgery (LVRS)...
  64. ncbi request reprint New treatment strategies for COPD. Pairing the new with the tried and true
    Claudia G Cote
    University of South Florida College of Medicine, Tampa, USA
    Postgrad Med 117:27-34. 2005
    ..With all of these options, a nihilistic attitude toward management of COPD is not justified...
  65. ncbi request reprint Inspiratory-to-total lung capacity ratio predicts mortality in patients with chronic obstructive pulmonary disease
    Ciro Casanova
    Respiratory Research Institute, Hospital Universitario La Candelaria, Carretera del Rosario s n, 38010 Santa Cruz de Tenerife, Spain
    Am J Respir Crit Care Med 171:591-7. 2005
    ..We propose that this ratio be considered in the assessment of patients with chronic obstructive pulmonary disease...
  66. ncbi request reprint A comparison of 5-day courses of dirithromycin and azithromycin in the treatment of acute exacerbations of chronic obstructive pulmonary disease
    Richard S Castaldo
    SUNY Buffalo School of Medicine, Buffalo, New York, USA
    Clin Ther 25:542-57. 2003
    ..The macrolide antibiotics, particularly second-generation agents such as dirithromycin and azithromycin, are among the antibiotic classes frequently recommended and used to treat upper and lower respiratory infections, including AECB...
  67. ncbi request reprint Predictors of mortality in chronic obstructive pulmonary disease
    Claudia G Cote
    University of South Florida, Tampa, FL, USA
    Clin Chest Med 28:515-24, v. 2007
    ..It also discusses the ability of an integrated, multidimensional tool to more broadly characterize COPD severity, assess response to therapeutic interventions and exacerbations, and predict mortality...