Affiliation: Tufts University
- Shaping bacterial genomes with integrative and conjugative elementsVincent Burrus
Department of Molecular Biology and Microbiology, Tufts University School of Medicine, and Howard Hughes Medical Institute, 136 Harrison Avenue, Boston, MA 02111, USA
Res Microbiol 155:376-86. 2004..Finally, we propose that by utilizing conserved integration sites, ICEs may promote the mobilization of genomic islands...
- Comparative ICE genomics: insights into the evolution of the SXT/R391 family of ICEsRachel A F Wozniak
Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
PLoS Genet 5:e1000786. 2009..Furthermore, our analyses suggest that there may be a network of phylogenetic relationships among sequences found in all types of mobile genetic elements...
- Genomic and functional analysis of ICEPdaSpa1, a fish-pathogen-derived SXT-related integrating conjugative element that can mobilize a virulence plasmidCarlos R Osorio
Microbiology Program, Tufts University School of Medicine, Boston, MA, USA
J Bacteriol 190:3353-61. 2008..Our findings reveal the plasticity of ICE genomes and demonstrate that ICEs can enable virulence gene transfer...
- Requirement for Vibrio cholerae integration host factor in conjugative DNA transferSarah M McLeod
Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Howard Hughes Medical Institute, 136 Harrison Avenue, Boston, MA 02111, USA
J Bacteriol 188:5704-11. 2006..Thus, the V. cholerae IHF mutant appears to have a general defect in conjugation. Escherichia coli IHF mutants were not impaired as donors or recipients of SXT or RP4, indicating that IHF is a V. cholerae-specific conjugation factor...
- SXT-related integrating conjugative element in New World Vibrio choleraeVincent Burrus
Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Jaharis 425, 136 Harrison Ave, Boston, MA 02111, USA
Appl Environ Microbiol 72:3054-7. 2006..Identification of ICEVchMex1 represents the first description of an SXT-related ICE in the Western Hemisphere. The significant differences between the SXT and ICEVchMex1 genomes suggest that these ICEs have evolved independently...
- The current ICE age: biology and evolution of SXT-related integrating conjugative elementsVincent Burrus
Department of Molecular Biology and Microbiology, Tufts University School of Medicine, and Howard Hughes Medical Institute Boston, MA 02111, USA
Plasmid 55:173-83. 2006..In this review, we discuss the diversity, evolution and biology of this family of ICEs...
- Control of SXT integration and excisionVincent Burrus
Department of Microbiology and Medicine, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA
J Bacteriol 185:5045-54. 2003..SXT excision and transfer from a donor containing pntB::SXT were reduced, suggesting that the SXT integration site may also influence the element's transmissibility...
- Formation of SXT tandem arrays and SXT-R391 hybridsVincent Burrus
Department of Molecular Biology and Microbiology, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA
J Bacteriol 186:2636-45. 2004..Thus, arrays of SXT-related elements promote the creation of novel ICEs...
- Evolution of genomic islands by deletion and tandem accretion by site-specific recombination: ICESt1-related elements from Streptococcus thermophilusGuillaume Pavlovic
, UMR INRA-UHP no. 1128, IFR no. 110, , , BP239, , France
Microbiology 150:759-74. 2004..A model for this evolution is proposed and its application to other genomic islands is discussed...
- The ICESt1 element of Streptococcus thermophilus belongs to a large family of integrative and conjugative elements that exchange modules and change their specificity of integrationVincent Burrus
Laboratoire de Génétique et Microbiologie, UMR INRA UHP no 1128, Faculte des Sciences, Universite Henri Poincare Nancy 1, BP239, 54506 Vandoeuvre les Nancy, France
Plasmid 48:77-97. 2002....
- Conjugative transposons: the tip of the icebergVincent Burrus
, UMR INRA-UHP 1128, IFR110, , , BP239, , France
Mol Microbiol 46:601-10. 2002..These elements evolve by acquisition or exchanges of modules with various transferable elements including at least ICEs and plasmids. The ICEs are probably widespread among the bacteria...
- Identification of the origin of transfer (oriT) and a new gene required for mobilization of the SXT/R391 family of integrating conjugative elementsDaniela Ceccarelli
Departement de Biologie, Centre d Etude et Valorisation de la Diversité Microbienne, Universite de Sherbrooke, Quebec, Canada
J Bacteriol 190:5328-38. 2008..Instead, mobI appears to be involved in the recognition of oriT(SXT)...