- Prevention of social stress-escalated cocaine self-administration by CRF-R1 antagonist in the rat VTAChristopher O Boyson
Department of Psychology, Tufts University, Medford, MA, USA
Psychopharmacology (Berl) 218:257-69. 2011..Stressful encounters can lead to activation of dopamine neurons in the ventral tegmental area (VTA), which are modulated by corticotropin releasing factor (CRF) neurons...
- Gene expression in aminergic and peptidergic cells during aggression and defeat: relevance to violence, depression and drug abuseKlaus A Miczek
Department of Psychology, Tufts University, 530 Boston Ave Bacon Hall, Medford, MA 02155, USA
Behav Genet 41:787-802. 2011..intermittent exposure to social stress, suggesting divergent neuroadaptations for increased vulnerability to cocaine self-administration vs. deteriorated reward mechanisms characteristic of depressive-like profiles...
- GABA(B) receptor modulation of serotonin neurons in the dorsal raphé nucleus and escalation of aggression in miceAki Takahashi
Department of Psychology, Tufts University, Medford, Massachusetts 02155, USA
J Neurosci 30:11771-80. 2010..These findings suggest that the indirect disinhibition of 5-HT neuron activity by presynaptic GABA(B) receptors on non-5-HT neurons in the DRN is one of the neurobiological mechanisms of escalated aggression...