Robert Berland

Summary

Affiliation: Tufts University
Country: USA

Publications

  1. ncbi request reprint An NFAT-dependent enhancer is necessary for anti-IgM-mediated induction of murine CD5 expression in primary splenic B cells
    R Berland
    Department of Pathology, Program in Immunology, Tufts University School of Medicine, Boston, MA 02111, USA
    J Immunol 161:277-85. 1998
  2. ncbi request reprint Origins and functions of B-1 cells with notes on the role of CD5
    Robert Berland
    Department of Pathology, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Annu Rev Immunol 20:253-300. 2002
  3. pmc Normal B-1a cell development requires B cell-intrinsic NFATc1 activity
    Robert Berland
    Department of Pathology and Graduate Program in Immunology, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA
    Proc Natl Acad Sci U S A 100:13459-64. 2003
  4. pmc A conserved enhancer element differentially regulates developmental expression of CD5 in B and T cells
    Robert Berland
    Department of Pathology, Tufts University School of Medicine, Boston, MA 02111, USA
    J Immunol 185:7537-43. 2010
  5. ncbi request reprint Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice
    Robert Berland
    Department of Pathology, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Immunity 25:429-40. 2006

Detail Information

Publications5

  1. ncbi request reprint An NFAT-dependent enhancer is necessary for anti-IgM-mediated induction of murine CD5 expression in primary splenic B cells
    R Berland
    Department of Pathology, Program in Immunology, Tufts University School of Medicine, Boston, MA 02111, USA
    J Immunol 161:277-85. 1998
    ..Therefore, the induction of B cell CD5 expression requires NFAT binding and binding to at least one of three additional sites in the CD5 enhancer...
  2. ncbi request reprint Origins and functions of B-1 cells with notes on the role of CD5
    Robert Berland
    Department of Pathology, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Annu Rev Immunol 20:253-300. 2002
    ..The CD5 molecule can function as a negative regulator of BCR signaling that may help prevent inappropriate activation of autoreactive B-1a cells...
  3. pmc Normal B-1a cell development requires B cell-intrinsic NFATc1 activity
    Robert Berland
    Department of Pathology and Graduate Program in Immunology, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA
    Proc Natl Acad Sci U S A 100:13459-64. 2003
    ..We also demonstrate that NFATc1 protein expression is elevated approximately 5-fold in B-1a cells compared with B-2 cells. This is the first definitive demonstration of a B cell-intrinsic function for an NFAT family transcription factor...
  4. pmc A conserved enhancer element differentially regulates developmental expression of CD5 in B and T cells
    Robert Berland
    Department of Pathology, Tufts University School of Medicine, Boston, MA 02111, USA
    J Immunol 185:7537-43. 2010
    ..Thus, this enhancer provides age- and tissue-specific regulation of CD5 expression and is an example of the utilization of different modes of regulation of expression in T and B cells...
  5. ncbi request reprint Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice
    Robert Berland
    Department of Pathology, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Immunity 25:429-40. 2006
    ..These results demonstrate that the particular threat of nucleic acid-containing autoantigens lies in their ability to bind both antigen receptor and TLR7...