Research Topics
| Ira B WilsonSummaryAffiliation: Tufts-New England Medical Center Country: USA Publications
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Publications
Quality of HIV care provided by nurse practitioners, physician assistants, and physiciansIra B Wilson
Tufts New England Medical Center, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, Massachusetts 02111, USA
Ann Intern Med 143:729-36. 2005..Nurse practitioners (NPs) and physician assistants (PAs) are primary care providers for patients with HIV in some clinics, but little is known about the quality of care that they provide...
Correlations among measures of quality in HIV care in the United States: cross sectional studyIra B Wilson
Department of Medicine, Institute for Clinical Research and Health Care Policy, Tufts New England Medical Center, Boston, MA 02111, USA
BMJ 335:1085. 2007..To determine whether a selected set of indicators can represent a single overall quality construct...
Cost-related skipping of medications and other treatments among Medicare beneficiaries between 1998 and 2000. Results of a national studyIra B Wilson
The Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, Boston, MA 02111, USA
J Gen Intern Med 20:715-20. 2005..To report rates of cost-related skipping of medications and other treatments, assess correlates of skipping, examine changes in skipping between 1998 and 2000, and identify factors associated with changes in skipping...
Physician-patient communication about prescription medication nonadherence: a 50-state study of America's seniorsIra B Wilson
Tufts New England Medical Center, Boston, MA 02111, USA
J Gen Intern Med 22:6-12. 2007..Understanding and improving the quality of medication management is particularly important in the context of the Medicare prescription drug benefit that took effect last January 2006...
Description of a clinical pharmacist intervention administered to primary care patients with depressionKathleen M Bungay
The Health Institute, The Institute for Clinical Research and Health Policy Studies, Department of Medicine, Tufts New England Medical Center, 750 Washington Street, Box 345, Boston, MA 02111, USA
Gen Hosp Psychiatry 26:210-8. 2004..Research that identifies relationships between the components (active ingredients) of an intervention and the outcomes of care will benefit future intervention strategies and contribute to improved and efficient care...
Physician specialization and antiretroviral therapy for HIVBruce E Landon
Received from the Division of General Medicine, Beth Israel Deaconess Medical Center BEL and the Department of Health Care Policy BEL, PDC, Harvard Medical School, Boston, Mass 02115, USA
J Gen Intern Med 18:233-41. 2003..The changing nature of HIV care has important implications for the types of physicians that can best care for patients with HIV infection...
Gender differences in quality of HIV care in Ryan White CARE Act-funded clinicsLisa R Hirschhorn
Harvard Medical School Division of AIDS, The Landmark Center, Harvard Medical School, Boston, Massachusetts 02215, USA
Womens Health Issues 16:104-12. 2006..We examined differences in care received by HIV-infected women and men in a national sample of Ryan White CARE Act-funded clinics and explored the influence of clinic characteristics on care quality...
Physician specialization and the quality of care for human immunodeficiency virus infectionBruce E Landon
Division of General Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA
Arch Intern Med 165:1133-9. 2005..We sought to assess the relationship between specialty training and expertise and the quality of care delivered to patients with HIV infection...
Importance of dose timing to achieving undetectable viral loadsChristopher J Gill
Center for International Health and Development, Boston University of Public Health, Boston, MA 02118, USA
AIDS Behav 14:785-93. 2010..We conclude that dose timing is also an important determinant of successful ART, and should be considered as an additional dimension to overall adherence...
Primary care experiences of medicare beneficiaries, 1998 to 2000Jana E Montgomery
The Health Institute, Division of Clinical Care Research, Tufts-New England Medical Center, Tufts University School of Medicine, Boston, MA, USA
J Gen Intern Med 19:991-8. 2004..In an era marked by substantial national investment in quality monitoring, measures of these elements of care are notably absent from the nation's portfolio of quality indicators...
The impact of a pharmacist intervention on 6-month outcomes in depressed primary care patientsDavid A Adler
Department of Medicine, The Health Institute, Division of Clinical Care Research, T NEMC, Boston, MA, USA
Gen Hosp Psychiatry 26:199-209. 2004..Difficult-to-treat subgroups may benefit from pharmacists' care...
Understanding the role of HIV load in determining weight change in the era of highly active antiretroviral therapyD Mkaya Mwamburi
Division of Geographic Medicine and Infectious Diseases, Tufts New England Medical Center, Boston, MA 02111, USA
Clin Infect Dis 40:167-73. 2005..In this prospective cohort study, we determined the relationship between human immunodeficiency virus (HIV) RNA load and body weight in patients with HIV infection...
Incident depression symptoms are associated with poorer HAART adherence: a longitudinal analysis from the Nutrition for Healthy Living studyDeborah Kacanek
Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA
J Acquir Immune Defic Syndr 53:266-72. 2010..To determine the relationship between incident depression symptoms and suboptimal adherence to HIV highly active antiretroviral therapy (HAART)...
A national study of the relationship of care site HIV specialization to early adoption of highly active antiretroviral therapyIra B Wilson
Institute for Clinical Research and Health Policy Studies, Tufts-New England Medical Center, Boston, Massachusetts, USA
Med Care 43:12-20. 2005..CONCLUSION: In 1996 there were wide variations in rates of HAART use by site of care. Low-volume sites that do not specialize in HIV care should take measures to ensure that HIV expertise is available to their patients...
Effects of a quality improvement collaborative on the outcome of care of patients with HIV infection: the EQHIV studyBruce E Landon
Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02115, USA
Ann Intern Med 140:887-96. 2004..Multi-institution collaborative quality improvement programs are a well-established and broadly applicable quality improvement strategy, but there is little systematic assessment their effectiveness...
Predictors and consequences of negative physician attitudes toward HIV-infected injection drug usersLin Ding
Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
Arch Intern Med 165:618-23. 2005..Providing education or experience-based exercises or ensuring that clinicians have adequate time to deal with complex problems might result in better attitudes and higher quality of care...
Using electronic drug monitor feedback to improve adherence to antiretroviral therapy among HIV-positive patients in ChinaLora L Sabin
Center for International Health and Development, Boston University, Boston, MA, USA
AIDS Behav 14:580-9. 2010..Mean CD4 count rose by 90 cells/microl and declined by 9 cells/microl among intervention and control subjects, respectively. EDM feedback as a counseling tool appears promising for management of HIV and other chronic diseases...
Insulin resistance in HIV-infected men and women in the nutrition for healthy living cohortClara Y Jones
Division of Nutrition and Infectious Disease, Department of Public Health and Family Medicine, Tufts University School of Medicine, Boston, MA 02111, USA
J Acquir Immune Defic Syndr 40:202-11. 2005..We evaluated insulin resistance (IR) in an HIV-infected cohort and compared our results with those of the National Health and Nutrition Examination Survey III (NHANES III)...
Provider-focused intervention increases adherence-related dialogue but does not improve antiretroviral therapy adherence in persons with HIVIra B Wilson
Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA 02111, USA
J Acquir Immune Defic Syndr 53:338-47. 2010..Physicians' limited knowledge of patients' antiretroviral adherence may reduce their ability to perform effective adherence counseling...
Prescription drug coverage and seniors: findings from a 2003 national surveyDana Gelb Safran
Health Institute at Tufts New England Medical Center, Boston, USA
Health Aff (Millwood) . 2005..We discuss MMA's potential to improve quality and the need to monitor performance...
Declines in dietary macronutrient intake in persons with HIV infection who develop depressionRita Isaac
1Nutrition Infection Unit, Department of Public Health and Family Medicine, Tufts University School of Medicine, Boston, MA, USA
Public Health Nutr 11:124-31. 2008..The effect of depression on dietary intake has not, to our knowledge, been examined in persons with HIV infection...
The relationship of post-traumatic stress disorder and depression to antiretroviral medication adherence in persons with HIVAna Maria Vranceanu
Department of Psychology, Massachusetts General Hospital, Harvard Medical School, and the Fenway Community Health Center, Boston, Massachusetts, USA
AIDS Patient Care STDS 22:313-21. 2008....
Cystatin C and creatinine in an HIV cohort: the nutrition for healthy living studyClara Y Jones
Tufts University School of Medicine, Boston, MA 02111, USA
Am J Kidney Dis 51:914-24. 2008..Serum creatinine level may underestimate the prevalence of CKD in subjects with decreased lean body mass or liver disease. Level of serum cystatin C, an alternative kidney function marker, is independent of lean body mass...
Depression screening instruments made good severity measures in a cross-sectional analysisWilliam H Rogers
The Health Institute, Institute for Clinical Research and Health Policy Studies, Tufts-New England Medical Center (T-NEMC, 750 Washington Street, Box 345, Boston, MA 02111, USA
J Clin Epidemiol 58:370-7. 2005..Good screeners for depression can also be good severity instruments. Exploiting screeners as severity instruments can significantly reduce response burden without sacrificing performance...
Primary care quality in the Medicare Program: comparing the performance of Medicare health maintenance organizations and traditional fee-for-service medicareDana Gelb Safran
The Health Institute, 750 Washington St, Box 345, Boston, MA 02111, USA
Arch Intern Med 162:757-65. 2002..Little information exists to inform beneficiaries' choices between the traditional fee-for-service (FFS) Medicare program and an HMO...
Prescription drug coverage and seniors: how well are states closing the gap?Dana Gelb Safran
Health Institute, Tufts New England Medical Center, Boston, USA
Health Aff (Millwood) . 2002..With erosion of state and private sources of prescription benefits expected, the findings speak to the need for a national policy solution...
The impact of a quality improvement program on systems, processes, and structures in medical clinicsD Keith McInnes
Department of Health Care Policy, Division of General Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA
Med Care 45:463-71. 2007..We sought to assess whether participation in a quality-improvement collaborative changed care processes, systems, and organization of outpatient human immunodeficiency virus (HIV) clinics...
Evolution and predictors of change in total bone mineral density over time in HIV-infected men and women in the nutrition for healthy living studyDenise L Jacobson
Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA
J Acquir Immune Defic Syndr 49:298-308. 2008..We evaluated the association of host factors, disease severity, and ART to changes in total body bone mineral density (total BMD) over time in HIV-infected men (n = 283) and women (n = 96)...
Inhaler costs and medication nonadherence among seniors with chronic pulmonary diseasePeter J Castaldi
Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA 02111, USA
Chest 138:614-20. 2010..Here, we examine the relationship between inhaler-specific out-of-pocket costs and CRN in CPD...
Optimal recall period and response task for self-reported HIV medication adherenceMinyi Lu
Institute for Clinical Research and Health Policy Studies, Department of Medicine, Tufts New England Medical Center, 345, 750 Washington St, Boston, MA 02111, USA
AIDS Behav 12:86-94. 2008..We conclude that 1-month recall periods may be more accurate than 3- or 7-day periods, and that items that ask respondents to rate their adherence may be more accurate than those that ask about frequencies or percents...
Better physician-patient relationships are associated with higher reported adherence to antiretroviral therapy in patients with HIV infectionJohn Schneider
Department of Medicine, University of Chicago, Ill, USA
J Gen Intern Med 19:1096-103. 2004..In addition, our data suggest that it is critical to investigate and incorporate patients' belief systems about antiretroviral therapy into adherence discussions, and to identify and treat mental disorders...
A comparison of the clinical and cost-effectiveness of 3 intervention strategies for AIDS wastingAbby H Shevitz
Nutrition Infection Unit, Department of Community Health, Tufts University, Boston, MA 02111, USA
J Acquir Immune Defic Syndr 38:399-406. 2005..To compare oxandrolone (OX) or strength training with nutrition alone (NA) for AIDS wasting...
Improving the self-report of HIV antiretroviral medication adherence: is the glass half full or half empty?Ira B Wilson
Tufts Medical Center, 345, Boston, MA 02111, USA
Curr HIV/AIDS Rep 6:177-86. 2009..We conclude with key questions for future research and methodologic recommendations...
Knowledge, beliefs, and health care practices relating to treatment of HIV in Vellore, IndiaAnne Marie Belz Chomat
Department of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Nutrition Infection Unit, Boston, Massachusetts 02111, USA
AIDS Patient Care STDS 23:477-84. 2009..Partnerships between the allopathic and traditional/complementary health sectors in research, policy, and practice are essential in building comprehensive HIV/AIDS treatment strategies...
Use of complementary and alternative therapies by patients with human immunodeficiency virus disease in the era of highly active antiretroviral therapyIoana Bica
Department of Medicine, Tufts University School of Medicine and New England Medical Center Hospitals, Boston, MA 02111, USA
J Altern Complement Med 9:65-76. 2003..Even among poorly educated, nongay male patients with insecure housing, rates of ingested CAM use were substantial. Physicians should routinely ask about ingested CAM therapy use and become knowledgeable about potential hazards...
HIV patients' experiences with inpatient and outpatient care: results of a national surveyIra B Wilson
Division of Clinical Care Research, Department of Medicine, Tufts New England Medical Center 345, 750 Washington Street, Boston, MA 02111, USA
Med Care 40:1149-60. 2002..Little is known about HIV patients' care experiences...
Work-related barriers and facilitators to antiretroviral therapy adherence in persons living with HIV infectionGilberto Torres-Madriz
The Department of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Boston, MA, USA
AIDS Behav 15:1475-82. 2011..These potential benefits of requesting modifications need to be weighed against the possible risks of workplace disclosure...
Difficulty swallowing and lack of receipt of highly active antiretroviral therapy predict acute weight loss in human immunodeficiency virus diseaseDenise L Jacobson
Department of Family Medicine and Community Health, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
Clin Infect Dis 37:1349-56. 2003..Even when HAART is being administered, clinicians should remain vigilant regarding weight loss, oral symptoms, and trouble swallowing...
A new method for evaluating the quality of medical interpretationM Barton Laws
Latin American Health Institute, Boston, MA 02116, USA
Med Care 42:71-80. 2004..To develop and implement a method to evaluate the quality of medical interpretation in a pediatric outpatient setting and explore the patterns and correlates of errors and failures in translation...
Antidepressant use: concordance between self-report and claims recordsAnne Kwon
Health Institute, Division of Clinical Care Research, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
Med Care 41:368-74. 2003..Researchers need valid methods to assess whether patients are taking their antidepressant medications. Two important sources of data on drug exposure are patients' self-reports and pharmacy claims...
Comparing megestrol acetate therapy with oxandrolone therapy for HIV-related weight loss: similar results in 2 monthsD Mkaya Mwamburi
Division of Geographic Medicine and Infectious Diseases, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
Clin Infect Dis 38:895-902. 2004..74). In conclusion, megestrol acetate therapy and oxandrolone therapy have similar effects on body weight and composition and are safe and well-tolerated during HAART...
Specialty training and specialization among physicians who treat HIV/AIDS in the United StatesBruce E Landon
Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
J Gen Intern Med 17:12-22. 2002..To assess the association of specialty training and experience in the care of HIV disease with HIV-specific knowledge, referral patterns, and HIV-related education activities...
Comparison of antiretroviral adherence questionsKarina M Berg
Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10467, USA
AIDS Behav 16:461-8. 2012..Though responses correlated with VL, single-item measures had higher correlations. Future studies should compare single-item questions to objective measures...
Relationship of HIV viral loads, CD4 counts, and HAART use to health-related quality of lifeChristopher J Gill
Division of Clinical Care Research, New England Medical Center, Boston, Massachusetts 02111, USA
J Acquir Immune Defic Syndr 30:485-92. 2002..For adherent patients, these adverse effects of HAART on PF are likely to be outweighed by the positive effects that HAART exerts through lowering VL and increasing CD4 counts...
Challenges in using mobile phones for collection of antiretroviral therapy adherence data in a resource-limited settingJessica E Haberer
Department of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA
AIDS Behav 14:1294-301. 2010..Despite near ubiquity of mobile phone technology in resource-limited settings, individual level collection of healthcare data presents challenges. Further research is needed for effective training and incentive methods...
Hospital economics of the hospitalistDouglas Gregory
Tufts-New England Medical Center, Boston, MA 02111, USA
Health Serv Res 38:905-18; discussion 919-22. 2003..Throughput improvements occasioned by the hospitalist program with high baseline occupancy levels are substantial and tend to favor a hospitalist program...
Barriers to adherence to antiretroviral medications among patients living with HIV in southern China: a qualitative studyLora L Sabin
Center for International Health and Development, Boston University, Boston, MA, USA
AIDS Care 20:1242-50. 2008..HIV care and service providers and policy makers in China responsible for HIV treatment should be aware of these important barriers to adherence...
Assessing the performance of a new depression screener for primary care (PC-SAD)William H Rogers
The Health Institute, Division of Clinical Care Research, Department of Medicine, New England Medical Center (NEMC, 750 Washington Street, Box 345, Boston, MA 02111, USA
J Clin Epidemiol 55:164-75. 2002..Investigators, clinicians, and health plans that want a DSM-IV-based depression screener can choose from among these three instruments, with known tradeoffs in sensitivity, respondent burden, and readability...
Do physicians not offer useful services because of coverage restrictions?Matthew K Wynia
Institute for Ethics, American Medical Association, Chicago, USA
Health Aff (Millwood) 22:190-7. 2003..It can be frustrating for doctors to discuss uncovered services with their patients, but open communication is necessary for shared decision making and to improve coverage decisions...
Voluntary physician switching by human immunodeficiency virus-infected individuals: a national study of patient, physician, and organizational factorsHector P Rodriguez
Harvard University, Cambridge, Massachusetts, USA
Med Care 45:189-98. 2007..We sought to assess which patient, physician, and organizational factors are related to voluntary physician switching among human immunodeficiency virus (HIV)-infected patients...
Regarding: "Antidepressant treatment improves adherence to antiretroviral therapy among depressed HIV-infected patients"Ira B Wilson
J Acquir Immune Defic Syndr 41:254-5; author reply 255. 2006
Clinician gender is more important than gender concordance in quality of HIV careMary Sue Beran
Robert Wood Johnson Clinical Scholars Program, University of California, Los Angeles, Los Angeles, California, USA
Gend Med 4:72-84. 2007..Less is known about how physician gender and gender concordance affect care for chronic illnesses, including HIV...
The effect of care team composition on the quality of HIV careHector P Rodriguez
University of Washington, Seattle, USA
Med Care Res Rev 65:88-113. 2008..These findings indicate both advantages and disadvantages to having multiple clinicians. More effort should be devoted to facilitating coordination when multiple clinicians provide care...
Disparities in HIV treatment and physician attitudes about delaying protease inhibitors for nonadherent patientsMitchell D Wong
Division of General Internal Medicine and Health Services Research, University of California, Los Angeles, California 90095 1736, USA
J Gen Intern Med 19:366-74. 2004..Current HIV treatment guidelines recommend delaying antiretroviral therapy for nonadherent patients, which some fear may disproportionately affect certain populations and contribute to disparities in care...
Falling into line: the impact of utilization review hassles on physicians' adherence to insurance contractsSaul J Weiner
University of Illinois at Chicago, USA
J Clin Ethics 15:139-48. 2004
Measuring deception: test-retest reliability of physicians' self-reported manipulation of reimbursement rules for patientsJonathan B VanGeest
American Medical Association, USA
Med Care Res Rev 59:184-96. 2002..Specifically, the three items reported here can be used to produce a reliable summary measure of physicians' manipulation of reimbursement rules to help patients obtain care that physicians perceive as necessary...
The reliability of survey assessments of characteristics of medical clinicsPeter V Marsden
Department of Sociology, Harvard University, Cambridge, MA 02138, USA
Health Serv Res 41:265-83. 2006..Studies of such characteristics should report the organizational level reliability of the measures used...
Research Grants
- Coding Audiotapes of Clinic Visits for Adherence ContentIra Wilson; Fiscal Year: 2006..While this work focuses on adherence with ARVs for HIV disease, the GMIAS has been designed to be easily generalizable to other conditions and research problems in MD-PT communication. ..
- Midcareer Investigator Award Patient-Oriented ResearchIra Wilson; Fiscal Year: 2007..Third, because of the Tufts University Sackler School MS/PhD Program in Clinical Research there is an existing, successful training infrastructure that provides both trainees and junior faculty the opportunity to learn research skills. ..
