Daniel E Weiner

Summary

Affiliation: Tufts-New England Medical Center
Country: USA

Publications

  1. ncbi request reprint The Framingham predictive instrument in chronic kidney disease
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    J Am Coll Cardiol 50:217-24. 2007
  2. pmc Uric acid and incident kidney disease in the community
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    J Am Soc Nephrol 19:1204-11. 2008
  3. doi request reprint The relationship between nontraditional risk factors and outcomes in individuals with stage 3 to 4 CKD
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 51:212-23. 2008
  4. ncbi request reprint Reducing versus discontinuing erythropoietin at high hemoglobin levels
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    J Am Soc Nephrol 18:3184-91. 2007
  5. ncbi request reprint Dialysis facility ownership and epoetin dosing in hemodialysis patients: an overview
    Daniel E Weiner
    Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Am J Kidney Dis 50:349-53. 2007
  6. ncbi request reprint Cardiovascular disease and subsequent kidney disease
    Essam F Elsayed
    Division of Nephrology, Department of Medicine, Tufts New England Medical Center, Campus Box 391, Boston, MA 02111
    Arch Intern Med 167:1130-6. 2007
  7. ncbi request reprint Kidney disease, Framingham risk scores, and cardiac and mortality outcomes
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, Mass 02111, USA
    Am J Med 120:552.e1-8. 2007
  8. ncbi request reprint Causes and consequences of chronic kidney disease: implications for managed health care
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston MA 02111, USA
    J Manag Care Pharm 13:S1-9. 2007
  9. ncbi request reprint Lowest systolic blood pressure is associated with stroke in stages 3 to 4 chronic kidney disease
    Daniel E Weiner
    Division of Nephrology, Box 391, Tufts New England Medical Center, Boston, MA 02111, USA
    J Am Soc Nephrol 18:960-6. 2007
  10. ncbi request reprint Cardiovascular outcomes and all-cause mortality: exploring the interaction between CKD and cardiovascular disease
    Daniel E Weiner
    Division of Nephrology, Department of Internal Medicine, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 48:392-401. 2006

Research Grants

  1. Kidney Disease, Stroke and Cognitive Impairment
    Daniel Weiner; Fiscal Year: 2007

Collaborators

Detail Information

Publications43

  1. ncbi request reprint The Framingham predictive instrument in chronic kidney disease
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    J Am Coll Cardiol 50:217-24. 2007
    ..We sought to determine the utility of the Framingham equations in individuals with chronic kidney disease (CKD)...
  2. pmc Uric acid and incident kidney disease in the community
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    J Am Soc Nephrol 19:1204-11. 2008
    ....
  3. doi request reprint The relationship between nontraditional risk factors and outcomes in individuals with stage 3 to 4 CKD
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 51:212-23. 2008
    ..Chronic kidney disease is associated with increased risk for cardiovascular disease and mortality. Both traditional and nontraditional cardiovascular disease risk factors may contribute...
  4. ncbi request reprint Reducing versus discontinuing erythropoietin at high hemoglobin levels
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    J Am Soc Nephrol 18:3184-91. 2007
    ....
  5. ncbi request reprint Dialysis facility ownership and epoetin dosing in hemodialysis patients: an overview
    Daniel E Weiner
    Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Am J Kidney Dis 50:349-53. 2007
  6. ncbi request reprint Cardiovascular disease and subsequent kidney disease
    Essam F Elsayed
    Division of Nephrology, Department of Medicine, Tufts New England Medical Center, Campus Box 391, Boston, MA 02111
    Arch Intern Med 167:1130-6. 2007
    ..Chronic kidney disease is a risk factor for cardiovascular disease (CVD); however, it is uncertain if CVD is a risk factor for progression or development of kidney disease...
  7. ncbi request reprint Kidney disease, Framingham risk scores, and cardiac and mortality outcomes
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, Mass 02111, USA
    Am J Med 120:552.e1-8. 2007
    ..The Framingham equations were developed to predict incident coronary heart disease. It remains unknown how the presence of chronic kidney disease affects their performance...
  8. ncbi request reprint Causes and consequences of chronic kidney disease: implications for managed health care
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston MA 02111, USA
    J Manag Care Pharm 13:S1-9. 2007
    ....
  9. ncbi request reprint Lowest systolic blood pressure is associated with stroke in stages 3 to 4 chronic kidney disease
    Daniel E Weiner
    Division of Nephrology, Box 391, Tufts New England Medical Center, Boston, MA 02111, USA
    J Am Soc Nephrol 18:960-6. 2007
    ..CKD and elevated SBP are independent risk factors for incident stroke. In CKD, individuals with the lowest BP are at increased risk for stroke. This pattern is not seen in the general population...
  10. ncbi request reprint Cardiovascular outcomes and all-cause mortality: exploring the interaction between CKD and cardiovascular disease
    Daniel E Weiner
    Division of Nephrology, Department of Internal Medicine, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 48:392-401. 2006
    ..Concurrently, CVD may promote CKD, resulting in a vicious cycle. We evaluated this hypothesis by exploring whether CKD and CVD have an additive or synergistic effect on future cardiovascular and mortality outcomes...
  11. pmc Waist-to-hip ratio and body mass index as risk factors for cardiovascular events in CKD
    Essam F Elsayed
    Department of Medicine, Tufts Medical Center, Boston, MA, USA
    Am J Kidney Dis 52:49-57. 2008
    ..Waist-to-hip ratio (WHR) is less influenced by muscle and bone mass than body mass index (BMI). We compared WHR and BMI as risk factors for cardiac events (myocardial infarction and fatal coronary disease) in persons with CKD...
  12. doi request reprint Waist-to-hip ratio, body mass index, and subsequent kidney disease and death
    Essam F Elsayed
    Nephrology Research Center, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 52:29-38. 2008
    ..Chronic kidney disease (CKD) and obesity are important public health concerns. We examined the association between anthropomorphic measures and incident CKD and mortality...
  13. pmc Depression and cognitive function in maintenance hemodialysis patients
    Brian T Agganis
    Division of Nephrology, Tufts Medical Center, Boston, MA, USA
    Am J Kidney Dis 56:704-12. 2010
    ..Both depression and cognitive impairment are common in hemodialysis patients, are associated with adverse clinical outcomes, and place an increased burden on health care resources...
  14. ncbi request reprint Kidney disease as a risk factor for recurrent cardiovascular disease and mortality
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 44:198-206. 2004
    ..Few studies have evaluated the effect of CKD on cardiovascular events in a diverse community-based population with underlying CVD...
  15. pmc Frequency of and risk factors for poor cognitive performance in hemodialysis patients
    Mark J Sarnak
    Division of Nephrology, Tufts Medical Center, Boston, MA, USA
    Neurology 80:471-80. 2013
    ..There are few detailed data on cognition in patients undergoing dialysis. We evaluated the frequency of and risk factors for poor cognitive performance using detailed neurocognitive testing...
  16. ncbi request reprint Anemia as a risk factor for cardiovascular disease and all-cause mortality in diabetes: the impact of chronic kidney disease
    Panagiotis T Vlagopoulos
    Division of Nephrology, Tufts New England Medical Center, 750 Washington Street, Box 391, Boston, MA 02111, USA
    J Am Soc Nephrol 16:3403-10. 2005
    ..66) for all-cause mortality. Anemia was not a risk factor for any outcome in those without CKD (P > 0.2 for all outcomes). In persons with diabetes, anemia is primarily a risk factor for adverse outcomes in those who also have CKD...
  17. ncbi request reprint Chronic kidney disease as a risk factor for cardiovascular disease and all-cause mortality: a pooled analysis of community-based studies
    Daniel E Weiner
    Division of Nephrology, Department of Clinical Care Research, Tufts New England Medical Center, Boston, Massachusetts, USA
    J Am Soc Nephrol 15:1307-15. 2004
    ..It is hypothesized that this effect may be due to more frequent or more severe subclinical vascular disease secondary to hypertension or diabetes in black individuals...
  18. pmc Computerized decision support for EPO dosing in hemodialysis patients
    Dana C Miskulin
    Tufts Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 54:1081-8. 2009
    ..The present study explored the hypothesis that computerized dosing of intravenous erythropoietin (EPO) would increase the percentage of hemoglobin (Hb) values within the target range and reduce staff time spent on anemia management...
  19. doi request reprint Measures of blood pressure and cognition in dialysis patients
    Lena M Giang
    Department of Medicine, Division of Nephrology, Tufts Medical Center, Boston, MA, USA
    Hemodial Int 17:24-31. 2013
    ..We found no association between different measures of blood pressure and cognitive function in cross-sectional analysis. Longitudinal studies are needed to confirm these results...
  20. ncbi request reprint Effects of anemia and left ventricular hypertrophy on cardiovascular disease in patients with chronic kidney disease
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, 750 Washington Street, Box 391, Boston, MA 02111, USA
    J Am Soc Nephrol 16:1803-10. 2005
    ..15 [95% CI, 2.62 to 6.56] and 3.92 [95% CI, 2.05 to 7.48]; P = 0.02 and 0.01 for interaction term, respectively). The combination of anemia and LVH in CKD identifies a high-risk population...
  21. pmc Nadir hemoglobin levels after discontinuation of epoetin in hemodialysis patients
    Jose A Calvo
    Tufts Medical Center and Tufts University School of Medicine, Boston, Massachusetts, USA
    Clin J Am Soc Nephrol 5:1621-7. 2010
    ..In hemodialysis patients, both hemoglobin variability and targeting normalization of hemoglobin may have adverse consequences. There are few data on epoetin management in patients achieving high hemoglobin levels...
  22. pmc CKD classification based on estimated GFR over three years and subsequent cardiac and mortality outcomes: a cohort study
    Daniel E Weiner
    Division of Nephrology, Tufts Medical Center, 800 Washington Street, Boston, MA 02111, USA
    BMC Nephrol 10:26. 2009
    ..It is unknown whether defining chronic kidney disease (CKD) based on one versus two estimated glomerular filtration rate (eGFR) assessments changes the prognostic importance of reduced eGFR in a community-based population...
  23. pmc Cognitive function and dialysis adequacy: no clear relationship
    Lena M Giang
    Tufts Medical Center, Boston, MA 02111, USA
    Am J Nephrol 33:33-8. 2011
    ..The impact of dialysis dose on cognitive function remains uncertain, particularly in the current era of increased dialysis dose and flux...
  24. doi request reprint Cognitive dysfunction and depression in adult kidney transplant recipients: baseline findings from the FAVORIT Ancillary Cognitive Trial (FACT)
    Aron M Troen
    Nutrition and Neurocognition Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA
    J Ren Nutr 22:268-76.e1-3. 2012
    ..Accordingly, we assessed the prevalence of cognitive impairment and depressive symptoms in transplant recipients and their association with kidney function, plasma total homocysteine, and B-vitamin concentrations...
  25. pmc Cardiovascular disease and cognitive function in maintenance hemodialysis patients
    Daniel E Weiner
    Division of Nephrology, Tufts Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 58:773-81. 2011
    ....
  26. ncbi request reprint Hematocrit and left ventricular mass: the Framingham Heart study
    Manish G Amin
    Division of Clinical Care Research, Department of Medicine, Tufts New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    J Am Coll Cardiol 43:1276-82. 2004
    ....
  27. ncbi request reprint Subcortical cognitive impairment in dialysis patients
    Arema A Pereira
    Department of Medicine, Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Hemodial Int 11:309-14. 2007
    ..These results suggest that, despite relatively normal MMSE scores, mild cognitive impairment may be prevalent in hemodialysis patients. The pattern of cognitive dysfunction is primarily subcortical in nature...
  28. pmc Kidney function, albuminuria and age-related macular degeneration in NHANES III
    Daniel E Weiner
    Division of Nephrology, Department of Medicine, Tufts Medical Center and Tufts University School of Medicine, Boston, MA, USA
    Nephrol Dial Transplant 26:3159-65. 2011
    ..Accordingly, we explored a population-based cohort of US adults to examine if markers of kidney disease identify a higher risk population for prevalent AMD...
  29. ncbi request reprint Cognitive function in dialysis patients
    Arema A Pereira
    Department of Medicine, Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 45:448-62. 2005
    ..We explore potential measures to reduce cognitive impairment in this population. We conclude that additional research is needed in this area...
  30. doi request reprint FGF-23 and cognitive performance in hemodialysis patients
    David A Drew
    Division of Nephrology, Department of Medicine, Tufts Medical Center, Boston, MA, USA
    Hemodial Int 18:78-86. 2014
    ..1st quartile). FGF-23 was associated with worse performance on a composite memory score, including after adjustment for measures of mineral metabolism. High FGF-23 levels in hemodialysis patients may contribute to cognitive impairment. ..
  31. doi request reprint The Central American epidemic of CKD
    Daniel E Weiner
    Division of Nephrology, Tufts Medical Center and Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Clin J Am Soc Nephrol 8:504-11. 2013
    ....
  32. pmc Albuminuria, cognitive functioning, and white matter hyperintensities in homebound elders
    Daniel E Weiner
    Division of Nephrology, Tufts Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 53:438-47. 2009
    ..Albuminuria, a kidney marker of microvascular disease, may herald microvascular disease elsewhere, including in the brain...
  33. pmc Anatomic brain disease in hemodialysis patients: a cross-sectional study
    David A Drew
    Division of Nephrology, Department of Medicine, Tufts Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 61:271-8. 2013
    ..Using magnetic resonance imaging of the brain, we compared the prevalence of brain abnormalities in hemodialysis patients with that in a control population without known kidney disease...
  34. pmc Chronic kidney disease and end-stage renal disease in the elderly population: current prevalence, future projections, and clinical significance
    Lesley A Stevens
    Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA
    Adv Chronic Kidney Dis 17:293-301. 2010
    ....
  35. pmc Managing dyslipidemia in chronic kidney disease
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts, USA
    J Gen Intern Med 19:1045-52. 2004
    ..One potentially modifiable risk factor for CVD in patients with CKD is dyslipidemia. In the current manuscript we review observational and trial data assessing dyslipidemia and its treatment in this patient population...
  36. doi request reprint Medicare reimbursement policies and hemodialysis vascular access outcomes: a need for change
    Michael Allon
    Division of Nephrology, University of Alabama at Birmingham, 1530 Third Avenue S, Birmingham, AL 35294, USA
    J Am Soc Nephrol 22:426-30. 2011
    ..The following position paper outlines the financial barriers to improved vascular access outcomes and our proposals for a future CMS demonstration project...
  37. doi request reprint Chronic kidney disease associated with environmental toxins and exposures
    Peter Soderland
    Renal Section, Boston University School of Medicine, Boston, MA, USA
    Adv Chronic Kidney Dis 17:254-64. 2010
    ..The effects of these agents may be modulated by genetic susceptibility and other comorbid conditions and may lead to the development of acute and CKD. In this article, we present environmental factors that are associated with CKD...
  38. doi request reprint What can we learn from the U.S. expanded end-stage renal disease bundle?
    James D Chambers
    The Center for the Evaluation of Value and Risk in Health, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA 02111, USA
    Health Policy 110:164-71. 2013
    ..Bundled payment policies offer opportunities and challenges. Their success will be determined not only by impacts on cost containment, but also to the extent they encourage high quality care...
  39. pmc Chronic kidney disease in Nicaragua: a qualitative analysis of semi-structured interviews with physicians and pharmacists
    Oriana Ramírez-Rubio
    Boston University School of Public Health, Boston, MA, USA
    BMC Public Health 13:350. 2013
    ..This study examines health professionals´ perceptions regarding etiology of these conditions and their treatment approaches, including use of potentially nephrotoxic medications...
  40. ncbi request reprint Microalbuminuria: a marker of cardiovascular risk
    Daniel E Weiner
    Am J Kidney Dis 42:596-8. 2003
  41. ncbi request reprint In the literature: cognitive impairment in hemodialysis patients
    Essam Elsayed
    Am J Kidney Dis 49:183-5. 2007
  42. doi request reprint The cognition-kidney disease connection: lessons from population-based studies in the United States
    Daniel E Weiner
    Am J Kidney Dis 52:201-4. 2008
  43. ncbi request reprint The challenges of the next 5 years
    Andrew S Levey
    Am J Kidney Dis 49:1-2. 2007

Research Grants2

  1. Kidney Disease, Stroke and Cognitive Impairment
    Daniel Weiner; Fiscal Year: 2007
    ..He has assembled a multidisciplinary team with excellent mentors in an exemplary clinical research environment in order to accomplish the aims of this proposal and develop as an independent clinical researcher. ..