Research Topics
Genomes and GenesSpecies | Anastassios G PittasSummaryAffiliation: Tufts-New England Medical Center Country: USA Publications
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Publications
The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysisAnastassios G Pittas
Division of Endocrinology, Diabetes and Metabolism, Tufts New England Medical Center, Boston, MA 02111, USA
J Clin Endocrinol Metab 92:2017-29. 2007..When data were available to combine, meta-analyses were performed, and summary odds ratios (OR) are presented...
The effects of the dietary glycemic load on type 2 diabetes risk factors during weight lossAnastassios G Pittas
Division of Endocrinology, Diabetes and Metabolism, Tufts New England Medical Center, 750 Washington Street, 268, Boston, MA 02111, USA
Obesity (Silver Spring) 14:2200-9. 2006..To compare the effects of two calorie-restricted diets that differ in glycemic load (GL) on glucose tolerance and inflammation...
The effects of calcium and vitamin D supplementation on blood glucose and markers of inflammation in nondiabetic adultsAnastassios G Pittas
Department of Endocrinology, Diabetes, and Metabolism, Tufts New England Medical Center, Boston, MA 02111, USA
Diabetes Care 30:980-6. 2007..We sought to compare the effects of combined calcium and vitamin D supplementation versus placebo on blood glucose and markers of inflammation in nondiabetic adults aged > or =65 years...
Dietary composition and weight loss: can we individualize dietary prescriptions according to insulin sensitivity or secretion status?Anastassios G Pittas
Division of Endocrinology, Diabetes and Metabolism, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
Nutr Rev 64:435-48. 2006..In particular, characteristics of insulin dynamics, such as insulin sensitivity or insulin secretion status, may interact with diets that vary in macronutrient composition to influence the weight loss achieved with a hypocaloric diet...
Insulin therapy and in-hospital mortality in critically ill patients: systematic review and meta-analysis of randomized controlled trialsAnastassios G Pittas
Division of Endocrinology, Diabetes and Metabolism and Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, 750 Washington Street 268, Boston, MA 02111, USA
JPEN J Parenter Enteral Nutr 30:164-72. 2006..Hyperglycemia is common in critically ill hospitalized patients and has been associated with adverse outcomes, including increased mortality. In this review, we examine the effect of insulin therapy on mortality in critically ill patients...
Vitamin D and calcium intake in relation to type 2 diabetes in womenAnastassios G Pittas
Division of Endocrinology, Diabetes and Metabolism, Tufts New England Medical Center, 750 Washington Street 268, Boston, MA 02111, USA
Diabetes Care 29:650-6. 2006..The purpose of this study was to prospectively examine the association between vitamin D and calcium intake and risk of type 2 diabetes...
A low-glycemic load diet facilitates greater weight loss in overweight adults with high insulin secretion but not in overweight adults with low insulin secretion in the CALERIE TrialAnastassios G Pittas
Division of Endocrinology, Diabetes, and Metabolism, Tufts-New England Medical Center, 750 Washington Street #268, Boston, MA 02111, USA
Diabetes Care 28:2939-41. 2005
Interstitial glucose level is a significant predictor of energy intake in free-living women with healthy body weightAnastassios G Pittas
Division of Endocrinology, Diabetes and Metabolism, Tufts New England Medical Center, Boston, MA 02111, USA
J Nutr 135:1070-4. 2005..In addition, the CGMS may have utility in understanding the role of circulating glucose in energy regulation in free-living subjects under a wide range of different nutritional conditions...
Insulin therapy for critically ill hospitalized patients: a meta-analysis of randomized controlled trialsAnastassios G Pittas
Divisions of Endocrinology, Diabetes and Metabolism, Tufts New England Medical Center, Boston, Mass, USA
Arch Intern Med 164:2005-11. 2004..The objective of this meta-analysis was to determine the effect of insulin therapy initiated during hospitalization on mortality in adult patients with a critical illness...
Predicted 25-hydroxyvitamin D score and incident type 2 diabetes in the Framingham Offspring StudyEnju Liu
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
Am J Clin Nutr 91:1627-33. 2010..Accumulating evidence suggests that vitamin D is involved in the development of type 2 diabetes (T2D)...
Effects of vitamin D and calcium supplementation on pancreatic ? cell function, insulin sensitivity, and glycemia in adults at high risk of diabetes: the Calcium and Vitamin D for Diabetes Mellitus (CaDDM) randomized controlled trialJoanna Mitri
Division of Endocrinology, Diabetes, and Metabolism, Tufts Medical Center, Boston, MA 02111, USA
Am J Clin Nutr 94:486-94. 2011..A suboptimal vitamin D and calcium status has been associated with higher risk of type 2 diabetes in observational studies, but evidence from trials is lacking...
Genetic and environmental influences on factors associated with cardiovascular disease and the metabolic syndromeSonya J Elder
Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
J Lipid Res 50:1917-26. 2009..These results suggest that genetic variance has a dominant influence on total variance of factors associated with CVD and MetS and support the proposal of one or more underlying pathologies of MetS...
Plasma 25-hydroxyvitamin d is associated with markers of the insulin resistant phenotype in nondiabetic adultsEnju Liu
Jean Mayer USDA Human Nutrition Research Center on Aging, Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA
J Nutr 139:329-34. 2009..Among adults without diabetes, vitamin D status was inversely associated with surrogate fasting measures of insulin resistance. These results suggest that vitamin D status may be an important determinant for type 2 diabetes mellitus...
Association between serum osteocalcin and markers of metabolic phenotypeAnastassios G Pittas
Division of Endocrinology, Diabetes, and Metabolism, Tufts Medical Center, 800 Washington Street, 268, Boston, Massachusetts 02111, USA
J Clin Endocrinol Metab 94:827-32. 2009..Osteocalcin has been reported to contribute to the regulation of glucose tolerance and insulin secretion and sensitivity in experimental animals...
Systematic review: Vitamin D and cardiometabolic outcomesAnastassios G Pittas
Tufts Medical Center and Friedman School of Nutrition Science and Policy, and Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
Ann Intern Med 152:307-14. 2010..Vitamin D may modify risk for cardiometabolic outcomes (type 2 diabetes, hypertension, or cardiovascular disease)...
Vitamin D and diabetesAnastassios G Pittas
Division of Endocrinology, Diabetes and Metabolism, Tufts Medical Center, Boston, MA 02111, United States
J Steroid Biochem Mol Biol 121:425-9. 2010..Therefore, the hypothesis that vitamin D may modify diabetes risk needs to be confirmed in trials specifically designed for that purpose...
Inpatient medical errors involving glucose-lowering medications and their impact on patients: review of 2,598 incidents from a voluntary electronic error-reporting databaseRenee E Amori
Division of Endocrinology, Diabetes, and Metabolism, Tufts New England Medical Center, Boston, Massachusetts, USA
Endocr Pract 14:535-42. 2008..To describe characteristics of inpatient medical errors involving hypoglycemic medications and their impact on patient care...
Low or moderate dietary energy restriction for long-term weight loss: what works best?Sai Krupa Das
Energy Metabolism Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts, USA
Obesity (Silver Spring) 17:2019-24. 2009....
Role of vitamin D in adults requiring nutrition supportAnastassios G Pittas
Division of Endocrinology, Diabetes and Metabolism
JPEN J Parenter Enteral Nutr 34:70-8. 2010..Given the emerging role of vitamin D for a variety of acute and chronic conditions, the optimal vitamin D status in acutely ill patients as well as in patients requiring long-term nutrition therapy warrants further investigation...
Plasma 25-hydroxyvitamin D concentration and risk of incident type 2 diabetes in womenAnastassios G Pittas
Division of Endocrinology, Diabetes and Metabolism, Tufts Medical Center, Boston, Massachusetts, USA
Diabetes Care 33:2021-3. 2010..To determine the association between 25-hydroxyvitamin D (25-OHD) concentration and risk of incident type 2 diabetes...
Plasma 25-hydroxyvitamin D and progression to diabetes in patients at risk for diabetes: an ancillary analysis in the Diabetes Prevention ProgramAnastassios G Pittas
Division of Endocrinology, Diabetes, and Metabolism, Tufts Medical Center, Boston, Massachusetts, USA
Diabetes Care 35:565-73. 2012..To investigate the association between vitamin D status, assessed by plasma 25-hydroxyvitamin D, and risk of incident diabetes...
Management of glycemia in patients with diabetes mellitus and CKDNoah D Lubowsky
Division of Endocrinology, Diabetes, and Metabolism, Tufts-New England Medical Center, Boston, MA 02111, USA
Am J Kidney Dis 50:865-79. 2007
Vitamin D as a potential modifier of diabetes riskSeenia V Peechakara
St Elizabeth's Medical Center, Tufts-New England Medical Center, Boston, MA 02111, USA
Nat Clin Pract Endocrinol Metab 4:182-3. 2008
Meta-analysis: efficacy and safety of inhaled insulin therapy in adults with diabetes mellitusLisa Ceglia
Tufts-New England Medical Center, Boston, Massachusetts 02111, USA
Ann Intern Med 145:665-75. 2006..Until long-term safety data are available, inhaled insulin should be reserved for nonpregnant adults with diabetes who are opposed to injections and who would otherwise delay appropriate and timely therapy with insulin...
The role of glycemic index in type 2 diabetesSusan B Roberts
USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington St, Boston, MA 02111, USA
Nutr Clin Care 6:73-8. 2003..A low-GI diet might alter beta cell function, lipid profile, and hypercoagulability...
Nutrition interventions for prevention of type 2 diabetes and the metabolic syndromeAnastassios G Pittas
Division of Endocrinology, Diabetes, and Metabolism, Tufts-New England Medical Center, 750 Washington Street, NEMC #268, Boston, MA 02111, USA
Nutr Clin Care 6:79-88. 2003..This review presents the evidence for dietary components that may modify diabetes risk and suggests nutritional interventions that may be of benefit in preventing the disease...
Does glycemic control with insulin therapy play a role for critically ill patients in hospital?Arpita H Patel
Division of Endocrinology, Diabetes and Metabolism, Tufts-New England Medical Center, Boston, Mass, USA
CMAJ 174:917-8. 2006
Effect of chromium supplementation on glucose metabolism and lipids: a systematic review of randomized controlled trialsEthan M Balk
Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, 750 Washington St, NEMC 63, Boston, MA 02111, USA
Diabetes Care 30:2154-63. 2007..A systematic review of the effect of chromium supplementation on glucose metabolism and lipid levels...
Efficacy and safety of incretin therapy in type 2 diabetes: systematic review and meta-analysisRenee E Amori
Division of Endocrinology, Diabetes and Metabolism, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
JAMA 298:194-206. 2007..Pharmacotherapies that augment the incretin pathway have recently become available, but their role in the management of type 2 diabetes is not well defined...
Thiazolidinediones in the treatment of type 2 diabetesAnastassios G Pittas
Tufts University School of Medicine, New England Medical Center, Division of Endocrinology, Diabetes, Metabolism and Molecular Medicine, 750 Washington Street, NEMC 268, Boston, MA 02111, USA
Expert Opin Pharmacother 3:529-40. 2002....
Adipocytokines and insulin resistanceAnastassios G Pittas
Division of Endocrinology, Diabetes and Metabolism, Tufts-New England Medical Center, Boston, Massachusetts 02111, USA
J Clin Endocrinol Metab 89:447-52. 2004
Impact of admission hyperglycemia on hospital mortality in various intensive care unit populationsBrian W Whitcomb
Department of Epidemiology and Preventive Medicine, School of Medicine, University of Maryland Baltimore, Baltimore, MD, USA
Crit Care Med 33:2772-7. 2005....
Long-term effects of 2 energy-restricted diets differing in glycemic load on dietary adherence, body composition, and metabolism in CALERIE: a 1-y randomized controlled trialSai Krupa Das
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA
Am J Clin Nutr 85:1023-30. 2007..There remains no consensus about the optimal dietary composition for sustained weight loss...
Leukopenia and thrombocytopenia caused by thiazolidinedionesColleen Digman
Ann Intern Med 143:465-6. 2005
Research Grants
- Glycemic Index and Metabolic SyndromeANASTASSIOS PITTAS; Fiscal Year: 2005..abstract_text> ..
- Vitamin D Status and Incident Type 2 DiabetesANASTASSIOS PITTAS; Fiscal Year: 2007..We will adjust for potential diabetes confounders (demographic, medical and nutritional) that have been measured and we will also examine whether the association is modified by BMI or calcium intake. ..
