Mark S Link

Summary

Affiliation: Tufts-New England Medical Center
Country: USA

Publications

  1. ncbi request reprint Mechanically induced sudden death in chest wall impact (commotio cordis)
    Mark S Link
    Cardiac Arrhythmia Service, New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Prog Biophys Mol Biol 82:175-86. 2003
  2. ncbi request reprint High incidence of pacemaker syndrome in patients with sinus node dysfunction treated with ventricular-based pacing in the Mode Selection Trial (MOST)
    Mark S Link
    Tufts New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    J Am Coll Cardiol 43:2066-71. 2004
  3. doi request reprint Protecting our children from the consequences of chest blows on the playing field: a time for science over marketing
    Mark S Link
    Cardiac Arrhythmia Center, Tufts Medical Center, Boston, Massachusetts 02111, USA
    Pediatrics 122:437-9. 2008
  4. ncbi request reprint How to manage athletes with syncope
    Mark S Link
    The New England Cardiac Arrhythmia Center, Division of Cardiology, Tufts New England Medical Center, Boston, MA 02111, USA
    Cardiol Clin 25:457-66, vii. 2007
  5. ncbi request reprint Equivalent arrhythmic risk in patients recently diagnosed with dilated cardiomyopathy compared with patients diagnosed for 9 months or more
    Kevin J Makati
    Tufts University School of Medicine New England Medical Center, Boston, Massachusetts 02111, USA
    Heart Rhythm 3:397-403. 2006
  6. doi request reprint Sudden cardiac death in athletes
    Mark S Link
    Division of Cardiology, Cardiac Arrhythmia Service, Tufts New England Medical Center, Boston, MA 02111, USA
    Prog Cardiovasc Dis 51:44-57. 2008
  7. ncbi request reprint Automated external defibrillator arrhythmia detection in a model of cardiac arrest due to commotio cordis
    Mark S Link
    Tufts University School of Medicine and New England Medical Center, Boston, Massachusetts 02111, USA
    J Cardiovasc Electrophysiol 14:83-7. 2003
  8. ncbi request reprint Role of streptomycin-sensitive stretch-activated channel in chest wall impact induced sudden death (commotio cordis)
    Arthur R Garan
    New England Cardiac Arrhythmia Center, Tufts New England Medical Center, Boston, Massachusetts, USA
    J Cardiovasc Electrophysiol 16:433-8. 2005
  9. pmc Increased risk of paroxysmal atrial fibrillation episodes associated with acute increases in ambient air pollution
    David Q Rich
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Environ Health Perspect 114:120-3. 2006
  10. ncbi request reprint Failure of commercially available chest wall protectors to prevent sudden cardiac death induced by chest wall blows in an experimental model of commotio cordis
    Jonathan Weinstock
    Cardiac Arrhythmia Center, Division of Cardiology, Department of Medicine, Tufts University School of Medicine, Tufts New England Medical Center, Boston, Massachusetts, USA
    Pediatrics 117:e656-62. 2006

Detail Information

Publications87

  1. ncbi request reprint Mechanically induced sudden death in chest wall impact (commotio cordis)
    Mark S Link
    Cardiac Arrhythmia Service, New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Prog Biophys Mol Biol 82:175-86. 2003
    ..Activation of the K(+)(ATP) channel is a likely cause of the ventricular fibrillation produced by chest wall blows. Successful resuscitation is attainable with early defibrillation...
  2. ncbi request reprint High incidence of pacemaker syndrome in patients with sinus node dysfunction treated with ventricular-based pacing in the Mode Selection Trial (MOST)
    Mark S Link
    Tufts New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    J Am Coll Cardiol 43:2066-71. 2004
    ..We evaluated the incidence, predictors, and treatment of pacemaker syndrome in patients with sinus node dysfunction treated with ventricular-based (VVIR) pacing in the Mode Selection Trial (MOST)...
  3. doi request reprint Protecting our children from the consequences of chest blows on the playing field: a time for science over marketing
    Mark S Link
    Cardiac Arrhythmia Center, Tufts Medical Center, Boston, Massachusetts 02111, USA
    Pediatrics 122:437-9. 2008
  4. ncbi request reprint How to manage athletes with syncope
    Mark S Link
    The New England Cardiac Arrhythmia Center, Division of Cardiology, Tufts New England Medical Center, Boston, MA 02111, USA
    Cardiol Clin 25:457-66, vii. 2007
    ..This article addresses the topic of syncope and possible solutions for those athletes in whom it is diagnosed...
  5. ncbi request reprint Equivalent arrhythmic risk in patients recently diagnosed with dilated cardiomyopathy compared with patients diagnosed for 9 months or more
    Kevin J Makati
    Tufts University School of Medicine New England Medical Center, Boston, Massachusetts 02111, USA
    Heart Rhythm 3:397-403. 2006
    ....
  6. doi request reprint Sudden cardiac death in athletes
    Mark S Link
    Division of Cardiology, Cardiac Arrhythmia Service, Tufts New England Medical Center, Boston, MA 02111, USA
    Prog Cardiovasc Dis 51:44-57. 2008
    ..Recommendations for participation in competitive athletics generally follow the recently published 36th Bethesda Conference Eligibility Recommendations for Competitive Athletes with Cardiovascular Abnormalities...
  7. ncbi request reprint Automated external defibrillator arrhythmia detection in a model of cardiac arrest due to commotio cordis
    Mark S Link
    Tufts University School of Medicine and New England Medical Center, Boston, Massachusetts 02111, USA
    J Cardiovasc Electrophysiol 14:83-7. 2003
    ..In a swine model of commotio cordis designed to be most relevant to young children, we assessed the efficacy of a commercially available AED for recognition and termination of ventricular fibrillation...
  8. ncbi request reprint Role of streptomycin-sensitive stretch-activated channel in chest wall impact induced sudden death (commotio cordis)
    Arthur R Garan
    New England Cardiac Arrhythmia Center, Tufts New England Medical Center, Boston, Massachusetts, USA
    J Cardiovasc Electrophysiol 16:433-8. 2005
    ..In this study, a nonselective stretch-activated cation channel was pharmacologically blocked prior to chest blows to determine whether this channel represents a possible pathway by which commotio cordis events occur...
  9. pmc Increased risk of paroxysmal atrial fibrillation episodes associated with acute increases in ambient air pollution
    David Q Rich
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Environ Health Perspect 114:120-3. 2006
    ..ICDs also detect paroxysmal atrial fibrillation episodes (PAF) that result in rapid ventricular rates. In this same cohort of ICD patients, we assessed the association between ambient air pollution and episodes of PAF...
  10. ncbi request reprint Failure of commercially available chest wall protectors to prevent sudden cardiac death induced by chest wall blows in an experimental model of commotio cordis
    Jonathan Weinstock
    Cardiac Arrhythmia Center, Division of Cardiology, Department of Medicine, Tufts University School of Medicine, Tufts New England Medical Center, Boston, Massachusetts, USA
    Pediatrics 117:e656-62. 2006
    ..In the present experiment, we tested the effectiveness of commercially available chest protectors in preventing ventricular fibrillation (VF) that results from chest wall strikes with baseballs and lacrosse balls...
  11. ncbi request reprint Upper and lower limits of vulnerability to sudden arrhythmic death with chest-wall impact (commotio cordis)
    Mark S Link
    Center for the Cardiovascular Evaluation of Athletes and the Cardiac Arrhythmia Service, New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA
    J Am Coll Cardiol 41:99-104. 2003
    ..In an animal model of commotio cordis, sudden death with chest-wall impact, we sought to systematically evaluate the importance of impact velocity in the generation of ventricular fibrillation (VF) with baseball chest-wall impact...
  12. ncbi request reprint Evidence that nonsustained polymorphic ventricular tachycardia causes syncope (data from implantable cardioverter defibrillators)
    D Michael Farmer
    The New England Cardiac Arrhythmia Service, Tufts New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA
    Am J Cardiol 91:606-9. 2003
  13. pmc Acute exposure to air pollution triggers atrial fibrillation
    Mark S Link
    Cardiac Arrhythmia Service, Division of Cardiology, Tufts Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02459, USA
    J Am Coll Cardiol 62:816-25. 2013
    ..This study sought to evaluate the association of air pollution with the onset of atrial fibrillation (AF)...
  14. ncbi request reprint Importance of the autonomic nervous system in an experimental model of commotio cordis
    C William Stout
    The New England Cardiac Arrhythmia Center, Tufts New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Med Sci Monit 13:BR11-5. 2007
    ..In an experimental model of commotio cordis, the importance of the sympathetic and parasympathetic nervous system in the initiation of ventricular fibrillation was evaluated...
  15. ncbi request reprint Enalapril treatment and hospitalization with atrial tachyarrhythmias in patients with left ventricular dysfunction
    Alawi A Alsheikh-Ali
    Tufts New England Medical Center, Department of Medicine, Division of Cardiolgy, Boston, Mass, USA
    Am Heart J 147:1061-5. 2004
    ..We sought to determine whether enalapril treatment reduced hospitalizations with atrial tachyarrhythmias in patients with LV dysfunction...
  16. ncbi request reprint Significance of false negative electrocardiograms in preparticipation screening of athletes for hypertrophic cardiomyopathy
    Ethan J Rowin
    Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts Medical Center, Boston, Massachusetts, USA
    Am J Cardiol 110:1027-32. 2012
    ..In principle, this high false-negative rate of 10% represents an important limitation in applying 12-lead electrocardiography to large, apparently healthy athletic populations for the detection of HC...
  17. ncbi request reprint Reduced risk of sudden death from chest wall blows (commotio cordis) with safety baseballs
    Mark S Link
    Center for the Cardiovascular Evaluation of Athletes, The Cardiac Arrhythmia Center, New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Pediatrics 109:873-7. 2002
    ..In an experimental model of sudden death from baseball chest wall impact (commotio cordis), we sought to determine if sudden death by baseball impact could be reduced with safety baseballs...
  18. ncbi request reprint Inducible ventricular flutter and fibrillation predict for arrhythmia occurrence in coronary artery disease patients presenting with syncope of unknown origin
    Mark S Link
    The New England Cardiac Arrhythmiqa Service, New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    J Cardiovasc Electrophysiol 13:1103-8. 2002
    ..However, there are limited data on the prognosis of these patients in long-term follow-up...
  19. doi request reprint Time-dependence of appropriate implantable defibrillator therapy in patients with ischemic cardiomyopathy
    Alawi A Alsheikh-Ali
    Institute for Clinical Research and Health Policy Studies, New England Cardiac Arrhythmia Center, Department of Medicine, Tufts New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    J Cardiovasc Electrophysiol 19:784-9. 2008
    ..We assessed the incidence and time-dependence of appropriate ICD therapy in a routine clinical practice primary prevention population with prior myocardial infarction (MI) and reduced left ventricular ejection fraction (LVEF)...
  20. doi request reprint Advances in mechanisms of atrial fibrillation: structural remodeling, high-frequency fractionated electrograms, and reentrant AF drivers
    Kevin J Makati
    New England Cardiac Arrhythmia Center, Tufts New England Medical Center, Tufts University School of Medicine, Boston, MA, USA
    J Interv Card Electrophysiol 23:45-9. 2008
    ..This review addresses the complex relationship between remodeled atrial myocardium and reentry and explores the role of CFAEs in AF maintenance...
  21. ncbi request reprint Frequent ICD shocks due to double sensing in patients with bi-ventricular implantable cardioverter defibrillators
    Amin Al-Ahmad
    New England Cardiac Arrhythmia Center, Department of Medicine, Tufts New England Medical Center, 750 Washington Street, Box 197, Boston, MA 02111, USA
    J Interv Card Electrophysiol 9:377-81. 2003
    ..Appropriate programming of the ICD can prevent episodes of inappropriate shocks...
  22. ncbi request reprint Commotio cordis--sudden cardiac death with chest wall impact
    Christopher Madias
    Cardiac Arrhythmia Center, Division of Cardiology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    J Cardiovasc Electrophysiol 18:115-22. 2007
    ..The development of more effective chest protectors and more widespread use of automated external defibrillators at youth sporting events are needed...
  23. doi request reprint Cell membrane stretch and chest blow-induced ventricular fibrillation: commotio cordis
    Christopher Madias
    Cardiac Arrhythmia Center, Tufts Medical Center, Boston, Massachusetts 02111, USA
    J Cardiovasc Electrophysiol 19:1304-9. 2008
    ..Disruption of cell cytoskeleton that anchors the cell membrane prior to precordial blows offers the opportunity to explore whether cell membrane deformation is critical to commotio cordis...
  24. ncbi request reprint Cryoablation of the pulmonary veins using a novel balloon catheter
    Arthur Garan
    New England Medical Center, Tufts University School of Medicine, Boston, MA, USA
    J Interv Card Electrophysiol 15:79-81. 2006
    ..We evaluated the ability of a novel balloon-based cryogenic catheter system in achieving transmural lesions for PV isolation...
  25. ncbi request reprint Clinical results with catheter ablation: AV junction, atrial fibrillation and ventricular tachycardia
    Jonathan Weinstock
    Cardiac Arrhythmia Center, Division of Cardiology, Department of Medicine, Tufts University School of Medicine, Tufts New England Medical Center, 750 Washington Street, Boston, MA 02111, USA
    J Interv Card Electrophysiol 9:275-88. 2003
    ....
  26. ncbi request reprint Use of antiarrhythmics and implantable cardioverter-defibrillators in congestive heart failure
    N A Mark Estes
    Cardiac Arrhythmia Center, Division of Cardiology, Department of Medicine, Tufts University School of Medicine, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Am J Cardiol 91:45D-52D. 2003
    ..However, these drugs have the potential to adversely affect defibrillator function, and knowledge of these effects is important when using this strategy...
  27. ncbi request reprint High risk of ventricular arrhythmias in patients with nonischemic dilated cardiomyopathy presenting with syncope
    Robert S Phang
    Tufts New England Medical Center, Boston, Massachusetts, USA
    Am J Cardiol 97:416-20. 2006
    ..In conclusion, patients with NIDC presenting with syncope are a high-risk group, with event rates similar to patients with NIDC presenting with sustained arrhythmias, and should be considered for ICD therapy...
  28. ncbi request reprint Hypertrophic cardiomyopathy is predominantly a disease of left ventricular outflow tract obstruction
    Martin S Maron
    Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts New England Medical Center, Boston, MA 02111, USA
    Circulation 114:2232-9. 2006
    ..We sought to prospectively define the prevalence, clinical profile, and significance of left ventricular (LV) outflow tract obstruction under resting conditions and with physiological exercise in a large HCM cohort...
  29. ncbi request reprint Atrioventricular nodal reverse facilitation in connexin40-deficient mice
    Wei Zhu
    Cardiac Arrhythmia Service, New England Medical Center, Boston, MA, USA
    Heart Rhythm 2:1231-7. 2005
    ..Facilitation is an important physiologic property of the atrioventricular (AV) node. Previous studies demonstrated abnormal AV conduction in connexin (Cx)40-deficient mice...
  30. doi request reprint Precordial thump for cardiac arrest is effective for asystole but not for ventricular fibrillation
    Christopher Madias
    Cardiac Arrhythmia Center, Division of Cardiology, Tufts Medical Center, Boston, MA 02111, USA
    Heart Rhythm 6:1495-500. 2009
    ..e., commotio cordis), they paradoxically have been regarded as potential therapy for cardiac arrest. In commotio cordis, impact energy and resultant peak left ventricular (LV) pressure are important variables in VF initiation...
  31. doi request reprint Preparticipation athletic screening including an electrocardiogram: an unproven strategy for prevention of sudden cardiac death in the athlete
    N A Mark Estes
    Department of Medicine, New England Cardiac Arrhythmia Center, The Tufts Cardiovascular Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Prog Cardiovasc Dis 54:451-4. 2012
    ..Currently, athletes are best protected by a strategy of secondary prevention with improvements in resuscitation and emergency action plans...
  32. doi request reprint Reduced diameter spheres increases the risk of chest blow-induced ventricular fibrillation (commotio cordis)
    John Kalin
    Cardiac Arrhythmia Center, Division of Cardiology, Tufts Medical Center, Boston, Massachusetts, USA
    Heart Rhythm 8:1578-81. 2011
    ..However, the risk of ventricular fibrillation (VF) relative to the shape of the impact object is not known...
  33. ncbi request reprint Herbal medicine: beneficial effects, side effects, and promising new research in the treatment of arrhythmias
    C William Stout
    NEMC Box 197, Tufts New England Medical Center, 750 Washington Street, Boston, MA 02111, USA
    Curr Cardiol Rep 5:395-401. 2003
    ..Finally, research that has been done in this field, focusing on those compounds that have been shown to be biologically active in the treatment of cardiac arrhythmias, are reviewed...
  34. doi request reprint Athletes and arrhythmias
    Mark S Link
    Division of Medicine, Cardiac Arrhythmia Center, Tufts Medical Center, Boston, Massachusetts 02111, USA
    J Cardiovasc Electrophysiol 21:1184-9. 2010
    ..Treatment strategies for athletes are focused for the return to athletics. Guidelines for treatment will be derived from the 36th Bethesda Guidelines for athletes, and the European Society of Cardiology (ESC) guidelines for athletes...
  35. ncbi request reprint Mechanically induced ventricular fibrillation (commotio cordis)
    Mark S Link
    Tufts University School of Medicine, New England Medical Center, Boston, Massachusetts
    Heart Rhythm 4:529-32. 2007
  36. ncbi request reprint Use of the AutoCapture Pacing System with implantable defibrillator leads
    John P Marenco
    New England Medical Center, Boston, MA, USA
    Pacing Clin Electrophysiol 26:471-3. 2003
    ..This prospective study tested the compatibility of the AC system with bipolar ICD leads...
  37. doi request reprint New paradigms in the prevention of sudden cardiac arrest and heart failure treatment
    Mustafa Dohadwala
    Division of Electrophysiology, Department of Cardiology, Tufts Medical Center, Boston, MA 02111, USA
    Curr Cardiol Rep 13:377-86. 2011
    ..Paradoxically, patients with less severe heart failure are at higher relative risk of sudden cardiac death. Defining which patients are best treated with implantable defibrillators and resynchronization is the purpose of this review...
  38. ncbi request reprint Testing of a new T-wave subtraction algorithm as an aid to localizing ectopic atrial beats
    John P Marenco
    Tufts University School of Medicine, New England Medical Center Hospitals, Boston, MA 02111, USA
    Ann Noninvasive Electrocardiol 8:55-9. 2003
    ..A method to uncover such "buried" P waves using a standard 12-lead surface ECG would be clinically useful and could potentially be a noninvasive guide to catheter ablation of focal atrial tachycardia...
  39. ncbi request reprint Assessment of risk for sudden cardiac death
    N A Mark Estes
    New England Cardiac Arrhythmia Center, New England Medical Center Hospital, Tufts University School of Medicine, Boston, Massachusetts, USA
    Curr Probl Cardiol 27:246-66. 2002
  40. ncbi request reprint Syncope in the patient with nonischemic dilated cardiomyopathy
    Sushil K Singh
    New England Cardiac Arrhythmia Center, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Pacing Clin Electrophysiol 27:97-100. 2004
  41. ncbi request reprint Cardiac arrhythmias in the athlete: the evolving role of electrophysiology
    Mark S Link
    New England Medical Center, Box 197, 750 Washington Street, Boston, MA 02111, USA
    Curr Sports Med Rep 1:75-85. 2002
    ..Ventricular arrhythmias that occur in the athlete without structural heart disease are not thought to be life threatening. Athletes with structural heart disease and those with exertional syncope merit a complete evaluation...
  42. ncbi request reprint Echocardiographic evidence of left atrial abnormality in young patients with lone paroxysmal atrial fibrillation
    Robert S Phang
    Tufts New England Medical Center, Boston, Massachusetts, USA
    Am J Cardiol 94:511-3. 2004
    ....
  43. pmc Air pollution and the triggering of cardiac arrhythmias
    Mark S Link
    The Cardiac Arrhythmia Center, Division of Cardiology, Tufts Medical Center, Boston, Massachusetts 02111, USA
    Curr Opin Cardiol 25:16-22. 2010
    ..The data have been strongest with respect to ventricular arrhythmias but there is accumulating evidence that air pollution is also associated with supraventricular arrhythmias...
  44. ncbi request reprint Cardiovascular toxicities of performance-enhancing substances in sports
    Ritesh Dhar
    Department of Clinical Care Research, Institute for Clinical Research and Health Policy Studies, Tufts University New England Medical Center, Boston, MA 02111, USA
    Mayo Clin Proc 80:1307-15. 2005
    ....
  45. doi request reprint Early repolarization associated with ventricular arrhythmias in patients with chronic coronary artery disease
    Ravi B Patel
    Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Circ Arrhythm Electrophysiol 3:489-95. 2010
    ..It is unknown whether there is an association between early repolarization and ventricular arrhythmias in the coronary artery disease (CAD) population...
  46. pmc Increased inducibility of ventricular tachycardia and decreased heart rate variability in a mouse model for type 1 diabetes: effect of pravastatin
    Mohammad Rajab
    Tufts Medical Center, Tufts University School of Medicine, Boston, Massachusetts
    Am J Physiol Heart Circ Physiol 305:H1807-16. 2013
    ..In this new animal model for the study of the pathogenesis of VT in type 1 diabetes, pravastatin may play a role in the prevention of VT by attenuating parasympathetic dysfunction. ..
  47. doi request reprint Prediction and prevention of sudden death in young populations: the role of ECG screening
    Kevin R Dougherty
    New England Cardiac Arrhythmia Center, The Tufts Cardiovascular Center, Department of Medicine, Tufts University School of Medicine, 750 Washington Street, Boston, MA 02111, USA
    J Interv Card Electrophysiol 36:167-75. 2013
    ..From a health policy perspective, additional data are needed from robust registries and carefully designed trials before advancing ECG screening in youth...
  48. doi request reprint Incidence and significance of pacemaker and implantable cardioverter-defibrillator lead masses discovered during transesophageal echocardiography
    Brian C Downey
    Department of Medicine, Division of Cardiology, Tufts Medical Center, Boston, MA 02111, USA
    Pacing Clin Electrophysiol 34:679-83. 2011
    ..The finding of a lead-associated mass on transesophageal echocardiogram (TEE) raises concern for endocarditis. However, the incidence and clinical importance of lead masses is not currently known...
  49. doi request reprint Marked variability in susceptibility to ventricular fibrillation in an experimental commotio cordis model
    Alawi A Alsheikh-Ali
    Cardiac Arrhythmia Center, Division of Cardiology, Tufts Medical Center, 800 Washington St, Box 197, Boston, MA 02111, USA
    Circulation 122:2499-504. 2010
    ..Using our model of commotio cordis, we evaluated individual animal susceptibility to VF induction and assessed animal characteristics that might be involved...
  50. ncbi request reprint Durability of repaired sensing leads equivalent to that of new leads in implantable cardioverter defibrillator patients with sensing abnormalities
    Srijoy Mahapatra
    Cardiac Arrhythmia Service, Tufts University School of Medicine, New England Medical Center, Boston 02111, Massachusetts, USA
    Pacing Clin Electrophysiol 26:2225-9. 2003
    ..The strategy of lead repair, when technically feasible, should thus be considered in all patients with sensing abnormalities secondary to insulation breaks...
  51. pmc Parasympathetic response in chick myocytes and mouse heart is controlled by SREBP
    Ho Jin Park
    Molecular Cardiology Research Institute, Department of Medicine, Tufts New England Medical Center and Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    J Clin Invest 118:259-71. 2008
    ..These results demonstrate a relationship between lipid metabolism and parasympathetic response that may play a role in arrhythmogenesis...
  52. ncbi request reprint Sudden cardiac death in athletes
    Olaf Hedrich
    Tufts New England Medical Center, Cardiac Arrhythmia Service, Division of Cardiology, 750 Washington Street, Box 197, Boston, MA 02111, USA
    Curr Cardiol Rep 8:316-22. 2006
    ....
  53. ncbi request reprint A primer on arrhythmias in patients with hypertrophic cardiomyopathy
    Katy E Bockstall
    Cardiac Arrhythmia Center, Tufts Medical Center, 800 Washington Street, Box 197, Boston, MA 02111, USA
    Curr Cardiol Rep 14:552-62. 2012
    ..Emerging possible risk factors include atrial fibrillation, myocardial ischemia, left ventricular outflow tract obstruction, genetic mutations, left ventricular apical aneurysms, myocardial fibrosis, and end stage disease...
  54. pmc Association of air pollution with increased incidence of ventricular tachyarrhythmias recorded by implanted cardioverter defibrillators
    Douglas W Dockery
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02215, USA
    Environ Health Perspect 113:670-4. 2005
    ..The associations with sulfate suggest a link with stationary fossil fuel combustion sources...
  55. ncbi request reprint Adverse cardiovascular events temporally associated with ma huang, an herbal source of ephedrine
    David Samenuk
    Division of Cardiology, New England Medical Center, Boston, MA 02111, USA
    Mayo Clin Proc 77:12-6. 2002
    ..To evaluate possible cardiovascular toxic effects associated with use of dietary supplements containing ma huang, an herbal source of ephedrine...
  56. ncbi request reprint Advances in implantable cardioverter defibrillators
    Craig Swygman
    New England Medical Center, Boston, Massachusetts, USA
    Curr Opin Cardiol 17:24-8. 2002
    ..Future advances in devices will likely lead to improved arrhythmia classification, more advanced automated features, and additional features including more sophisticated sensors and biventricular pacing systems...
  57. ncbi request reprint Comparison of survival and other complications after heart transplantation in patients taking amiodarone before surgery versus those not taking amiodarone
    Patrick J Blomberg
    Division of Cardiology, Tufts University Medical School, Tufts New England Medical Center, Boston, Massachusetts, USA
    Am J Cardiol 93:379-81. 2004
    ..These findings raise further concern about the use of amiodarone treatment in patients with heart failure before undergoing HT...
  58. ncbi request reprint Significance and relation between magnitude of left ventricular hypertrophy and heart failure symptoms in hypertrophic cardiomyopathy
    Martin S Maron
    Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Am J Cardiol 95:1329-33. 2005
    ..In conclusion, no direct relation was evident between symptoms of heart failure and magnitude of LV wall thickness, with implications for the natural history of HC...
  59. ncbi request reprint A public access defibrillation programme in non-inpatient hospital areas
    Franklin D Friedman
    Tufts University School of Medicine, Emergency Physician, Tufts New England Medical Center, Tufts New England Medical Center, 750 Washington Street, Boston, MA 02111, USA
    Resuscitation 69:407-11. 2006
    ..Their use in hospital arrests is less well documented, but they offer the opportunity to improve survival in the hospital setting also...
  60. doi request reprint Sudden cardiac death in young athletes and nonathletes
    Brian J Cross
    Cardiac Arrhythmia Center, Tufts Medical Center, Boston, Massachusetts, USA
    Curr Opin Crit Care 17:328-34. 2011
    ..This article will review the incidence and most common causes of sudden cardiac death (SCD) in healthy young adults, including competitive athletes, as well as members of the general population...
  61. ncbi request reprint Implantable defibrillators in long QT syndrome, Brugada syndrome, hypertrophic cardiomyopathy, and arrhythmogenic right ventricular cardiomyopathy
    Mustafa Dohadwala
    Department of Medicine, The Cardiac Arrhythmia Center, Tufts Medical Center, 800 Washington Street, Box 197, Boston, MA 02111, USA
    Cardiol Clin 32:305-18. 2014
    ..Risk stratification is crucial in identifying those at greatest risk to provide lifesaving therapy with an ICD while avoiding complications in those unlikely to receive benefit. ..
  62. ncbi request reprint Ventricular Arrhythmias in the North American Multidisciplinary Study of ARVC: Predictors, Characteristics, and Treatment
    Mark S Link
    Tufts Medical Center, Cardiac Arrhythmia Center, Boston, Massachusetts Electronic address
    J Am Coll Cardiol 64:119-25. 2014
    ..Arrhythmogenic right ventricular cardiomyopathy (ARVC) is associated with sudden cardiac death. However, the selection of patients for implanted cardioverter-defibrillators (ICDs), as well as programming of the ICD, is unclear...
  63. pmc Short-term effects of ketamine and isoflurane on left ventricular ejection fraction in an experimental Swine model
    Benjamin Wessler
    New England Cardiac Arrhythmia Center, Tufts Medical Center, Boston, MA 02111, USA
    ISRN Cardiol 2011:582658. 2011
    ..The addition of isoflurane to ketamine did not significantly change LV function. A significant number of animals had returned to preanesthesia LV function with sympathetic stimulation...
  64. ncbi request reprint Task Force 10: automated external defibrillators
    Robert J Myerburg
    J Am Coll Cardiol 45:1369-71. 2005
  65. ncbi request reprint Prevalence of sensing abnormalities in dual chamber implantable cardioverter defibrillators
    Mohammad Saeed
    University of Texas Medical Branch, Galveston, TX 77555 0553, USA
    Ann Noninvasive Electrocardiol 8:219-26. 2003
    ..The clinical efficacy of ICD therapy depends on accurate sensing of intracardiac signals and sensing algorithms. We investigated the occurrence of sensing abnormalities in patients with dual chamber ICDs...
  66. ncbi request reprint Clinical profile and spectrum of commotio cordis
    Barry J Maron
    Minneapolis Heart Institute Foundation, 920 E 28th St, Suite 60, Minneapolis, MN 55407, USA
    JAMA 287:1142-6. 2002
    ..Although blunt, nonpenetrating chest blows causing sudden cardiac death (commotio cordis) are often associated with competitive sports, dangers implicit in such blows can extend into many other life activities...
  67. ncbi request reprint Implantable cardioverter-defibrillators and prevention of sudden cardiac death in hypertrophic cardiomyopathy
    Barry J Maron
    Hypertrophic Cardiomyopathy Center of the Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
    JAMA 298:405-12. 2007
    ..However, the effectiveness and appropriate selection of patients for this therapy is incompletely resolved...
  68. ncbi request reprint Inter-association task force recommendations on emergency preparedness and management of sudden cardiac arrest in high school and college athletic programs: a consensus statement
    Jonathan A Drezner
    University of Washington, Seattle, WA, USA
    Clin J Sport Med 17:87-103. 2007
    ..This consensus statement summarizes our current understanding of SCA in young athletes, defines the necessary elements for emergency preparedness, and establishes uniform treatment protocols for the management of SCA...
  69. ncbi request reprint Death in a young athlete due to commotio cordis despite prompt external defibrillation
    Barry J Maron
    Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
    Heart Rhythm 2:991-3. 2005
  70. ncbi request reprint Task Force 11: commotio cordis
    Barry J Maron
    J Am Coll Cardiol 45:1371-3. 2005
  71. ncbi request reprint Sudden cardiac death caused by innocent chest wall blows
    Mark S Link
    Ital Heart J 6:281-3. 2005
  72. ncbi request reprint Inter-association task force recommendations on emergency preparedness and management of sudden cardiac arrest in high school and college athletic programs: a consensus statement
    Jonathan A Drezner
    University of Washington, Seattle, Washington 98105, USA
    Heart Rhythm 4:549-65. 2007
    ..This consensus statement summarizes our current understanding of SCA in young athletes, defines the necessary elements for emergency preparedness, and establishes uniform treatment protocols for the management of SCA...
  73. ncbi request reprint Resuscitation in athletes: a sobering tale
    Mark S Link
    Heart Rhythm 3:760-1. 2006
  74. ncbi request reprint Unraveling the mystery of commotio cordis
    Mark S Link
    J Cardiovasc Electrophysiol 17:1018-9. 2006
  75. ncbi request reprint Treatment crossovers did not affect randomized treatment comparisons in the Mode Selection Trial (MOST)
    Anne S Hellkamp
    Duke Clinical Research Institute, Durham, North Carolina, USA
    J Am Coll Cardiol 47:2260-6. 2006
    ..We evaluated the impact of treatment crossovers on study results in the Mode Selection Trial (MOST)...
  76. ncbi request reprint Historical observation on commotio cordis
    Barry J Maron
    Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
    Heart Rhythm 3:605-6. 2006
  77. ncbi request reprint Evaluation of chest barriers for protection against sudden death due to commotio cordis
    Joseph J Doerer
    The Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA
    Am J Cardiol 99:857-9. 2007
    ....
  78. ncbi request reprint Gender-related differences in the clinical presentation and outcome of hypertrophic cardiomyopathy
    Iacopo Olivotto
    Regional Referral Center for Myocardial Diseases, Azienda Ospedaliera Universitaria Careggi, Florence, Italy
    J Am Coll Cardiol 46:480-7. 2005
    ..The goal of this study was to assess gender-related differences in a multicenter population with hypertrophic cardiomyopathy (HCM)...
  79. pmc Inter-association Task Force recommendations on emergency preparedness and management of sudden cardiac arrest in high school and college athletic programs: a consensus statement
    Jonathan A Drezner
    University of Washington, Seattle, WA 98105, USA
    J Athl Train 42:143-58. 2007
    ..This consensus statement summarizes our current understanding of SCA in young athletes, defines the necessary elements for emergency preparedness, and establishes uniform treatment protocols for the management of SCA...
  80. ncbi request reprint Primary prevention of sudden death as a novel treatment strategy in hypertrophic cardiomyopathy
    Barry J Maron
    The Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, 920 E 28th St, Suite 60, Minneapolis, Minn 55407, USA
    Circulation 107:2872-5. 2003
  81. ncbi request reprint Inter Association Task Force recommendations on emergency preparedness and management of sudden cardiac arrest in high school and college athletic programs: a consensus statement
    Jonathan A Drezner
    University of Washington Seattle, WA 98105, USA
    Prehosp Emerg Care 11:253-71. 2007
    ..This consensus statement summarizes our current understanding of SCA in young athletes, defines the necessary elements for emergency preparedness, and establishes uniform treatment protocols for the management of SCA...
  82. ncbi request reprint Implantable cardioverter-defibrillator therapy for prevention of sudden death in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia
    Domenico Corrado
    Divisione di Cardiologia e Patologia Cardiovascolare, Universita di Padova, Padova, Italy
    Circulation 108:3084-91. 2003
    ..Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a condition associated with the risk of sudden death (SD)...
  83. doi request reprint Cardiac safety of electrical stun guns: letting science and reason advance the debate
    Mark S Link
    Pacing Clin Electrophysiol 31:395-7. 2008
  84. ncbi request reprint Accentuation of pacing induced electrical dyssynchrony by preexisting conduction system disease and left ventricular dysfunction
    Mark S Link
    J Cardiovasc Electrophysiol 19:123-4. 2008
  85. ncbi request reprint Exercise and acute cardiovascular events placing the risks into perspective: a scientific statement from the American Heart Association Council on Nutrition, Physical Activity, and Metabolism and the Council on Clinical Cardiology
    Paul D Thompson
    Hartford Hospital, USA
    Circulation 115:2358-68. 2007
    ....