Andrew Levey

Summary

Affiliation: Tufts-New England Medical Center
Country: USA

Publications

  1. ncbi request reprint Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO)
    Andrew S Levey
    Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Kidney Int 67:2089-100. 2005
  2. ncbi request reprint Chronic kidney disease as a global public health problem: approaches and initiatives - a position statement from Kidney Disease Improving Global Outcomes
    A S Levey
    Tufts New England Medical Center, Boston, Massachusetts, USA
    Kidney Int 72:247-59. 2007
  3. doi request reprint Waist-to-hip ratio, body mass index, and subsequent kidney disease and death
    Essam F Elsayed
    Nephrology Research Center, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 52:29-38. 2008
  4. ncbi request reprint Relationship between C-reactive protein, albumin, and cardiovascular disease in patients with chronic kidney disease
    Vandana Menon
    Department of Medicine, Division of Clinical Care Research, Tufts New England Medical Center, Boston, MA, USA
    Am J Kidney Dis 42:44-52. 2003
  5. pmc Waist-to-hip ratio and body mass index as risk factors for cardiovascular events in CKD
    Essam F Elsayed
    Department of Medicine, Tufts Medical Center, Boston, MA, USA
    Am J Kidney Dis 52:49-57. 2008
  6. ncbi request reprint Comorbidity and its change predict survival in incident dialysis patients
    Dana C Miskulin
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 41:149-61. 2003
  7. ncbi request reprint Progression of chronic kidney disease: the role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition: a patient-level meta-analysis
    Tazeen H Jafar
    Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Ann Intern Med 139:244-52. 2003
  8. ncbi request reprint The rate of progression of renal disease may not be slower in women compared with men: a patient-level meta-analysis
    Tazeen H Jafar
    New England Medical Center, Tufts University School of Medicine, Boston, MA, USA
    Nephrol Dial Transplant 18:2047-53. 2003
  9. ncbi request reprint Comorbidity and other factors associated with modality selection in incident dialysis patients: the CHOICE Study. Choices for Healthy Outcomes in Caring for End-Stage Renal Disease
    Dana C Miskulin
    Division of Nephrology, New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 39:324-36. 2002
  10. pmc Role of adipose tissue in determining muscle mass in patients with chronic kidney disease
    Carmen Castaneda-Sceppa
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    J Ren Nutr 17:314-22. 2007

Research Grants

Detail Information

Publications86

  1. ncbi request reprint Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO)
    Andrew S Levey
    Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Kidney Int 67:2089-100. 2005
    ..Kidney disease treatment by dialysis and transplantation should be noted. Simple, uniform classifications of CKD by cause and by risks for kidney disease progression and CVD should be developed...
  2. ncbi request reprint Chronic kidney disease as a global public health problem: approaches and initiatives - a position statement from Kidney Disease Improving Global Outcomes
    A S Levey
    Tufts New England Medical Center, Boston, Massachusetts, USA
    Kidney Int 72:247-59. 2007
    ..KDIGO will work in collaboration with international and national public health organizations to facilitate implementation of these recommendations...
  3. doi request reprint Waist-to-hip ratio, body mass index, and subsequent kidney disease and death
    Essam F Elsayed
    Nephrology Research Center, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 52:29-38. 2008
    ..Chronic kidney disease (CKD) and obesity are important public health concerns. We examined the association between anthropomorphic measures and incident CKD and mortality...
  4. ncbi request reprint Relationship between C-reactive protein, albumin, and cardiovascular disease in patients with chronic kidney disease
    Vandana Menon
    Department of Medicine, Division of Clinical Care Research, Tufts New England Medical Center, Boston, MA, USA
    Am J Kidney Dis 42:44-52. 2003
    ..Data are limited regarding relationships between CRP levels and glomerular filtration rate (GFR), nutritional indices, and CVD in patients with earlier stages of kidney disease...
  5. pmc Waist-to-hip ratio and body mass index as risk factors for cardiovascular events in CKD
    Essam F Elsayed
    Department of Medicine, Tufts Medical Center, Boston, MA, USA
    Am J Kidney Dis 52:49-57. 2008
    ..Waist-to-hip ratio (WHR) is less influenced by muscle and bone mass than body mass index (BMI). We compared WHR and BMI as risk factors for cardiac events (myocardial infarction and fatal coronary disease) in persons with CKD...
  6. ncbi request reprint Comorbidity and its change predict survival in incident dialysis patients
    Dana C Miskulin
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 41:149-61. 2003
    ..Longitudinal change in the comorbid illness burden of incident dialysis patients has not been measured. Comorbidity severity and its change may serve as important prognostic markers of survival, independent of other case-mix factors...
  7. ncbi request reprint Progression of chronic kidney disease: the role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition: a patient-level meta-analysis
    Tazeen H Jafar
    Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Ann Intern Med 139:244-52. 2003
    ..Angiotensin-converting enzyme (ACE) inhibitors reduce blood pressure and urine protein excretion and slow the progression of chronic kidney disease...
  8. ncbi request reprint The rate of progression of renal disease may not be slower in women compared with men: a patient-level meta-analysis
    Tazeen H Jafar
    New England Medical Center, Tufts University School of Medicine, Boston, MA, USA
    Nephrol Dial Transplant 18:2047-53. 2003
    ..Therefore, we undertook this analysis to explore the independent association of renal disease progression with gender...
  9. ncbi request reprint Comorbidity and other factors associated with modality selection in incident dialysis patients: the CHOICE Study. Choices for Healthy Outcomes in Caring for End-Stage Renal Disease
    Dana C Miskulin
    Division of Nephrology, New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 39:324-36. 2002
    ..Adjustment for case-mix differences in patients treated with PD versus HD is essential to the assessment of the independent effect of the dialysis modality on outcomes...
  10. pmc Role of adipose tissue in determining muscle mass in patients with chronic kidney disease
    Carmen Castaneda-Sceppa
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    J Ren Nutr 17:314-22. 2007
    ..Arm muscle area was used as an indicator of muscle mass...
  11. ncbi request reprint Relationship of phosphorus and calcium-phosphorus product with mortality in CKD
    Vandana Menon
    Division of Nephrology, Department of Medicine, Tufts New England Medical Center, Boston, MA, USA
    Am J Kidney Dis 46:455-63. 2005
    ..There are limited data investigating relationships of phosphorus and calcium-phosphorus product with outcomes in patients with chronic kidney disease (CKD) stages 3 to 4...
  12. pmc Key comorbid conditions that are predictive of survival among hemodialysis patients
    Dana Miskulin
    Division of Nephrology, Tufts Medical Center, 800 Washington Street, Box 391, Boston, MA 02111, USA
    Clin J Am Soc Nephrol 4:1818-26. 2009
    ..We sought to determine which conditions are most prognostic and whether comorbidity continues to contribute to a survival model once laboratory and clinical parameters have been accounted for...
  13. ncbi request reprint Glycosylated hemoglobin and mortality in patients with nondiabetic chronic kidney disease
    Vandana Menon
    Department of Medicine, Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts, USA
    J Am Soc Nephrol 16:3411-7. 2005
    ..43; P = 0.07). HbA(1c) is associated with increased mortality in nondiabetic kidney disease. Hyperglycemia may be a potential therapeutic target and HbA(1c) may be important as a risk stratification tool in this high-risk population...
  14. ncbi request reprint Level of kidney function as a risk factor for cardiovascular outcomes in the elderly
    Guruprasad Manjunath
    Department of Medicine, New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA
    Kidney Int 63:1121-9. 2003
    ..We evaluated whether the level of kidney function is an independent risk factor for CVD outcomes in the Cardiovascular Health Study (CHS), a cohort of subjects whose age at baseline was 65 years old or older...
  15. ncbi request reprint Expressing the Modification of Diet in Renal Disease Study equation for estimating glomerular filtration rate with standardized serum creatinine values
    Andrew S Levey
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Clin Chem 53:766-72. 2007
    ..We sought to reexpress the 4-variable Modification of Diet in Renal Disease (MDRD) Study equation for estimation of glomerular filtration rate (GFR) using serum creatinine (S(cr)) standardized to reference methods...
  16. ncbi request reprint Association between body mass index and CKD in apparently healthy men
    Rebecca P Gelber
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
    Am J Kidney Dis 46:871-80. 2005
    ..Conversely, their association with the development of CKD is less clear...
  17. ncbi request reprint Anemia as a risk factor for cardiovascular disease and all-cause mortality in diabetes: the impact of chronic kidney disease
    Panagiotis T Vlagopoulos
    Division of Nephrology, Tufts New England Medical Center, 750 Washington Street, Box 391, Boston, MA 02111, USA
    J Am Soc Nephrol 16:3403-10. 2005
    ..66) for all-cause mortality. Anemia was not a risk factor for any outcome in those without CKD (P > 0.2 for all outcomes). In persons with diabetes, anemia is primarily a risk factor for adverse outcomes in those who also have CKD...
  18. doi request reprint Baseline characteristics in the Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT)
    Marc A Pfeffer
    Cardiovascular Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    Am J Kidney Dis 54:59-69. 2009
    ....
  19. ncbi request reprint Cystatin C as a risk factor for outcomes in chronic kidney disease
    Vandana Menon
    Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Ann Intern Med 147:19-27. 2007
    ....
  20. ncbi request reprint Prevalence of ICD-9-CM codes for chronic kidney disease in individuals with cardiovascular disease risk factors
    Ashish Mahajan
    Tufts Medical Center Scientific and Clinical Research Center, Boston, Massachusetts, USA
    J Nephrol 22:523-33. 2009
    ..Chronic kidney disease (CKD) is a risk factor for cardiovascular disease (CVD)...
  21. doi request reprint Factors other than glomerular filtration rate affect serum cystatin C levels
    Lesley A Stevens
    Division of Nephrology, Clinical Care Research, Tufts Medical Center, Boston, Massachusetts 02111, USA
    Kidney Int 75:652-60. 2009
    ..Hence, we found that cystatin C is affected by factors other than GFR which should be considered when the GFR is estimated using serum levels of cystatin C...
  22. ncbi request reprint Kidney disease as a risk factor for recurrent cardiovascular disease and mortality
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 44:198-206. 2004
    ..Few studies have evaluated the effect of CKD on cardiovascular events in a diverse community-based population with underlying CVD...
  23. ncbi request reprint Serum C-reactive protein and leptin as predictors of kidney disease progression in the Modification of Diet in Renal Disease Study
    Mark J Sarnak
    New England Medical Center and Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Kidney Int 62:2208-15. 2002
    ..In vitro and in vivo data suggest that markers of inflammation and nutritional status may be risk factors for the progression of chronic kidney disease...
  24. ncbi request reprint Ethnic subgroup differences in hypertension in Pakistan
    Tazeen H Jafar
    Department of Community Health Sciences, Tufts University Medical School, Boston, Massachusetts, USA
    J Hypertens 21:905-12. 2003
    ..We conducted this study to explore the variations in hypertension within ethnic subgroups among South Asians...
  25. ncbi request reprint C-reactive protein and albumin as predictors of all-cause and cardiovascular mortality in chronic kidney disease
    Vandana Menon
    Department of Medicine, Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Kidney Int 68:766-72. 2005
    ..There are limited data evaluating the relationships between CRP, albumin, and outcomes in chronic kidney disease (CKD) stages 3 and 4...
  26. doi request reprint Cystatin C and creatinine in an HIV cohort: the nutrition for healthy living study
    Clara Y Jones
    Tufts University School of Medicine, Boston, MA 02111, USA
    Am J Kidney Dis 51:914-24. 2008
    ..Serum creatinine level may underestimate the prevalence of CKD in subjects with decreased lean body mass or liver disease. Level of serum cystatin C, an alternative kidney function marker, is independent of lean body mass...
  27. doi request reprint Current status and future perspectives for CKD testing
    Lesley A Stevens
    Division of Nephrology, Tufts Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 53:S17-26. 2009
    ..Repeated testing for urine protein and interpretation of GFR estimates in the context of kidney damage and the clinical context of patient presentation can help overcome these limitations...
  28. pmc A new equation to estimate glomerular filtration rate
    Andrew S Levey
    Tufts Medical Center, Boston, Massachusetts 02111, USA
    Ann Intern Med 150:604-12. 2009
    ..Equations to estimate glomerular filtration rate (GFR) are routinely used to assess kidney function. Current equations have limited precision and systematically underestimate measured GFR at higher values...
  29. doi request reprint Erythropoietic response and outcomes in kidney disease and type 2 diabetes
    Scott D Solomon
    Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02114, USA
    N Engl J Med 363:1146-55. 2010
    ..However, target-based strategies are confounded by each patient's individual hematopoietic response...
  30. pmc CKD classification based on estimated GFR over three years and subsequent cardiac and mortality outcomes: a cohort study
    Daniel E Weiner
    Division of Nephrology, Tufts Medical Center, 800 Washington Street, Boston, MA 02111, USA
    BMC Nephrol 10:26. 2009
    ..It is unknown whether defining chronic kidney disease (CKD) based on one versus two estimated glomerular filtration rate (eGFR) assessments changes the prognostic importance of reduced eGFR in a community-based population...
  31. ncbi request reprint Automatic reporting of estimated glomerular filtration rate--just what the doctor ordered
    Andrew S Levey
    Division of Nephrology, Department of Medicine, Tufts New England Medical Center, Boston, MA 02111, USA
    Clin Chem 52:2188-93. 2006
  32. ncbi request reprint The Framingham predictive instrument in chronic kidney disease
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    J Am Coll Cardiol 50:217-24. 2007
    ..We sought to determine the utility of the Framingham equations in individuals with chronic kidney disease (CKD)...
  33. ncbi request reprint Impact of creatinine calibration on performance of GFR estimating equations in a pooled individual patient database
    Lesley A Stevens
    Division of Nephrology, Tufts New England Medical Center, 750 Washington St, Box 391, Boston, MA 02111, USA
    Am J Kidney Dis 50:21-35. 2007
    ..Variation in performance of glomerular filtration rate (GFR) estimating equations is related to variation in calibration of the creatinine assay across clinical laboratories...
  34. ncbi request reprint Evaluation of the modification of diet in renal disease study equation in a large diverse population
    Lesley A Stevens
    Division of Nephrology, Tufts New England Medical Center, 750 Washington Street, Box 391, Boston, MA 02111, USA
    J Am Soc Nephrol 18:2749-57. 2007
    ..73 m(2). In individual patients, interpretation of GFR estimates near 60 ml/min per 1.73 m(2) should be interpreted with caution to avoid misclassification of chronic kidney disease in the context of the clinical setting...
  35. ncbi request reprint Cardiovascular disease and subsequent kidney disease
    Essam F Elsayed
    Division of Nephrology, Department of Medicine, Tufts New England Medical Center, Campus Box 391, Boston, MA 02111
    Arch Intern Med 167:1130-6. 2007
    ..Chronic kidney disease is a risk factor for cardiovascular disease (CVD); however, it is uncertain if CVD is a risk factor for progression or development of kidney disease...
  36. ncbi request reprint Dialysis facility ownership and epoetin dosing in hemodialysis patients: an overview
    Daniel E Weiner
    Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Am J Kidney Dis 50:349-53. 2007
  37. ncbi request reprint Body mass index and mortality in CKD
    Magdalena Madero
    Department of Medicine, Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 50:404-11. 2007
    ..Data are limited on the relationship of BMI with mortality in patients in the earlier stages of chronic kidney disease (CKD)...
  38. ncbi request reprint Surrogate end points for clinical trials of kidney disease progression
    Lesley A Stevens
    Division of Nephrology, Tufts New England Medical Center, 750 Washington Street, Box 391, Boston, MA 02111, USA
    Clin J Am Soc Nephrol 1:874-84. 2006
  39. doi request reprint The relationship between nontraditional risk factors and outcomes in individuals with stage 3 to 4 CKD
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 51:212-23. 2008
    ..Chronic kidney disease is associated with increased risk for cardiovascular disease and mortality. Both traditional and nontraditional cardiovascular disease risk factors may contribute...
  40. pmc Estimating GFR using serum cystatin C alone and in combination with serum creatinine: a pooled analysis of 3,418 individuals with CKD
    Lesley A Stevens
    Division of Nephrology, Tufts New England Medical Center, 750 Washington St, Box 391, Boston, MA 02111, USA
    Am J Kidney Dis 51:395-406. 2008
    ..We report the development and evaluation of GFR-estimating equations using serum cystatin C alone and serum cystatin C, serum creatinine, or both with demographic variables...
  41. doi request reprint A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease
    Marc A Pfeffer
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    N Engl J Med 361:2019-32. 2009
    ..Although darbepoetin alfa can effectively increase hemoglobin levels, its effect on clinical outcomes in these patients has not been adequately tested...
  42. pmc Development and validation of GFR-estimating equations using diabetes, transplant and weight
    Lesley A Stevens
    Tufts Medical Center, Boston, MA, USA
    Nephrol Dial Transplant 25:449-57. 2010
    ..Here, we describe the development and validation of this equation as well as other equations that incorporate diabetes, transplant and weight as additional predictor variables...
  43. doi request reprint Proteinuria as a surrogate outcome in CKD: report of a scientific workshop sponsored by the National Kidney Foundation and the US Food and Drug Administration
    Andrew S Levey
    Tufts Medical Center, Boston, MA, USA
    Am J Kidney Dis 54:205-26. 2009
    ..We recommend collaboration among many groups, including academia, industry, the FDA, and the National Institutes of Health, to share data from past and future studies...
  44. doi request reprint Effect of a very low-protein diet on outcomes: long-term follow-up of the Modification of Diet in Renal Disease (MDRD) Study
    Vandana Menon
    Department of Medicine, Division of Nephrology, Tufts Medical Center, Boston, MA, USA
    Am J Kidney Dis 53:208-17. 2009
    ..We examined the effect of a very low-protein diet on the development of kidney failure and death during long-term follow-up of the Modification of Diet in Renal Disease (MDRD) Study...
  45. ncbi request reprint Level of kidney function as a risk factor for atherosclerotic cardiovascular outcomes in the community
    Guruprasad Manjunath
    Division of Nephrology, New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    J Am Coll Cardiol 41:47-55. 2003
    ....
  46. ncbi request reprint Traditional cardiac risk factors in individuals with chronic kidney disease
    Katrin Uhlig
    Division of Nephrology, Department of Medicine, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Semin Dial 16:118-27. 2003
    ..Treatment recommendations are provided using evidence available from populations with CKD or evidence extrapolated from the general population when there are insufficient data on individuals with CKD...
  47. pmc Uric acid and incident kidney disease in the community
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    J Am Soc Nephrol 19:1204-11. 2008
    ....
  48. pmc Comparative performance of the CKD Epidemiology Collaboration (CKD-EPI) and the Modification of Diet in Renal Disease (MDRD) Study equations for estimating GFR levels above 60 mL/min/1.73 m2
    Lesley A Stevens
    Tufts Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 56:486-95. 2010
    ..Here, performance of a more accurate GFR-estimating equation, the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation, is reported by level of GFR and clinical characteristics...
  49. ncbi request reprint Kidney disease, Framingham risk scores, and cardiac and mortality outcomes
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, Boston, Mass 02111, USA
    Am J Med 120:552.e1-8. 2007
    ..The Framingham equations were developed to predict incident coronary heart disease. It remains unknown how the presence of chronic kidney disease affects their performance...
  50. ncbi request reprint Predicting 1 year mortality in an outpatient haemodialysis population: a comparison of comorbidity instruments
    Dana C Miskulin
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Nephrol Dial Transplant 19:413-20. 2004
    ..We compare the discriminatory accuracy of 1 year mortality predictions derived from four comorbidity instruments in a large representative US dialysis population...
  51. ncbi request reprint Factors associated with lipoprotein(a) in chronic kidney disease
    Katrin Uhlig
    Department of Medicine, Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 45:28-38. 2005
    ....
  52. ncbi request reprint Variation in the serum creatinine assay calibration: a practical application to glomerular filtration rate estimation
    Kalyani Murthy
    Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts, USA
    Kidney Int 68:1884-7. 2005
    ..Variation among clinical laboratories in calibration of serum creatinine assays is a source of error in glomerular filtration rate (GFR) estimation equations. We evaluated impact of this variation on GFR estimates...
  53. ncbi request reprint Effects of anemia and left ventricular hypertrophy on cardiovascular disease in patients with chronic kidney disease
    Daniel E Weiner
    Division of Nephrology, Tufts New England Medical Center, 750 Washington Street, Box 391, Boston, MA 02111, USA
    J Am Soc Nephrol 16:1803-10. 2005
    ..15 [95% CI, 2.62 to 6.56] and 3.92 [95% CI, 2.05 to 7.48]; P = 0.02 and 0.01 for interaction term, respectively). The combination of anemia and LVH in CKD identifies a high-risk population...
  54. ncbi request reprint Relationship between homocysteine and mortality in chronic kidney disease
    Vandana Menon
    Division of Nephrology, Department of Medicine, Tufts New England Medical Center, Boston, MA, USA
    Circulation 113:1572-7. 2006
    ..The relationship between total homocysteine (tHcy) and outcomes has not been investigated in patients with chronic kidney disease stages 3 to 4...
  55. ncbi request reprint Assessing kidney function--measured and estimated glomerular filtration rate
    Lesley A Stevens
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    N Engl J Med 354:2473-83. 2006
  56. ncbi request reprint Adiponectin and mortality in patients with chronic kidney disease
    Vandana Menon
    Tufts New England Medical Center, Division of Nephrology, 750 Washington Street, NEMC 391, Boston, MA 02111, USA
    J Am Soc Nephrol 17:2599-606. 2006
    ..Further studies are necessary to confirm this association and to elucidate the underlying mechanisms...
  57. ncbi request reprint Cardiovascular outcomes and all-cause mortality: exploring the interaction between CKD and cardiovascular disease
    Daniel E Weiner
    Division of Nephrology, Department of Internal Medicine, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Kidney Dis 48:392-401. 2006
    ..Concurrently, CVD may promote CKD, resulting in a vicious cycle. We evaluated this hypothesis by exploring whether CKD and CVD have an additive or synergistic effect on future cardiovascular and mortality outcomes...
  58. ncbi request reprint Low rates of testing and diagnostic codes usage in a commercial clinical laboratory: evidence for lack of physician awareness of chronic kidney disease
    Lesley A Stevens
    Tufts New England Medical Center, 750 Washington Street, Box 391, Boston, MA 02111, USA
    J Am Soc Nephrol 16:2439-48. 2005
    ....
  59. ncbi request reprint Effect of dietary protein restriction on the progression of kidney disease: long-term follow-up of the Modification of Diet in Renal Disease (MDRD) Study
    Andrew S Levey
    Division of Nephrology, Tufts New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Am J Kidney Dis 48:879-88. 2006
    ..We evaluated effects of protein restriction on kidney failure and all-cause mortality during extended follow-up of the Modification of Diet in Renal Disease Study...
  60. ncbi request reprint Lowest systolic blood pressure is associated with stroke in stages 3 to 4 chronic kidney disease
    Daniel E Weiner
    Division of Nephrology, Box 391, Tufts New England Medical Center, Boston, MA 02111, USA
    J Am Soc Nephrol 18:960-6. 2007
    ..CKD and elevated SBP are independent risk factors for incident stroke. In CKD, individuals with the lowest BP are at increased risk for stroke. This pattern is not seen in the general population...
  61. ncbi request reprint Progression risk, urinary protein excretion, and treatment effects of angiotensin-converting enzyme inhibitors in nondiabetic kidney disease
    David M Kent
    Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, 750 Washington Street 63, Boston, MA 02111, USA
    J Am Soc Nephrol 18:1959-65. 2007
    ..Patients with proteinuria <500 mg/d do not seem to benefit, even when at relatively high risk for progression...
  62. ncbi request reprint The effect of a lower target blood pressure on the progression of kidney disease: long-term follow-up of the modification of diet in renal disease study
    Mark J Sarnak
    Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Ann Intern Med 142:342-51. 2005
    ..Hypertension is a risk factor for progression of chronic kidney disease. The optimal blood pressure to slow progression is unknown...
  63. ncbi request reprint Measurement of kidney function
    Lesley A Stevens
    Division of Nephrology, Tufts University School of Medicine, Tufts New England Medical Center, 750 Washington Street, Box 391, Boston, MA 02111, USA
    Med Clin North Am 89:457-73. 2005
    ..The current recommended method is to use estimating equations based on serum creatinine and which incorporate demographic and clinical variables...
  64. pmc A comparison of change in measured and estimated glomerular filtration rate in patients with nondiabetic kidney disease
    Dawei Xie
    Center for Clinical Epidemiology and Biostatistics, Philadelphia, PA 19104, USA
    Clin J Am Soc Nephrol 3:1332-8. 2008
    ..The aims of this study were to examine the concordance between use of measured GFR (mGFR) and estimated GFR (eGFR) in tracking changes in kidney function over time among patients with moderately severe chronic kidney disease...
  65. ncbi request reprint Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey
    Josef Coresh
    Department of Epidemiology, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD, USA
    Am J Kidney Dis 41:1-12. 2003
    ....
  66. ncbi request reprint Rationale--Trial to Reduce Cardiovascular Events with Aranesp Therapy (TREAT): evolving the management of cardiovascular risk in patients with chronic kidney disease
    T Christian H Mix
    Department of Development and Medical Affairs, Amgen Inc, Thousand Oaks, Calif, USA
    Am Heart J 149:408-13. 2005
    ....
  67. ncbi request reprint Chronic kidney disease in the elderly--how to assess risk
    Lesley A Stevens
    N Engl J Med 352:2122-4. 2005
  68. ncbi request reprint High lipoprotein(a) levels and small apolipoprotein(a) size prospectively predict cardiovascular events in dialysis patients
    J Craig Longenecker
    Johns Hopkins University, Baltimore, Maryland, USA
    J Am Soc Nephrol 16:1794-802. 2005
    ..Both LMW apo(a) size and high Lp(a) level predict ASCVD risk in dialysis patients, but the association of ASCVD with LMW isoforms is stronger than the association with high Lp(a) concentration...
  69. ncbi request reprint Estimating the prevalence of low glomerular filtration rate requires attention to the creatinine assay calibration
    Josef Coresh
    J Am Soc Nephrol 13:2811-2; author reply 2812-6. 2002
  70. ncbi request reprint Serum creatinine as marker of kidney function in South Asians: a study of reduced GFR in adults in Pakistan
    Tazeen H Jafar
    Section of Nephrology, Department of Medicine, Clinical Epidemiology Unit, The Aga Khan University, P O Box 3500, Stadium Road, Karachi Sind 74800, Pakistan
    J Am Soc Nephrol 16:1413-9. 2005
    ..Inclusion of terms for ethnic and racial groups other than white and black might improve the performance of GFR estimating equations...
  71. ncbi request reprint Calibration and random variation of the serum creatinine assay as critical elements of using equations to estimate glomerular filtration rate
    Josef Coresh
    Department of Epidemiology, The Johns Hopkins University School of Hygiene and Public Health, Baltimore, MD, USA
    Am J Kidney Dis 39:920-9. 2002
    ..73 m2), but result in progressively larger differences at higher GFRs. Both clinical and research use of serum creatinine or equations to estimate GFR require knowledge of the calibration of the serum creatinine assay...
  72. ncbi request reprint Children in South Asia have higher body mass-adjusted blood pressure levels than white children in the United States: a comparative study
    Tazeen H Jafar
    Clinical Epidemiology Unit, Department of Community Health Sciences, Aga Khan University, PO Box 3500, Stadium Road, Karachi, Pakistan
    Circulation 111:1291-7. 2005
    ....
  73. ncbi request reprint Clinical implications of estimating equations for glomerular filtration rate
    Lesley A Stevens
    Ann Intern Med 141:959-61. 2004
  74. ncbi request reprint Early, intermediate, and long-term risk factors for mortality in incident dialysis patients: the Choices for Healthy Outcomes in Caring for ESRD (CHOICE) Study
    Laura C Plantinga
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Kidney Dis 49:831-40. 2007
    ..Knowing whether risk factors for mortality differ in dialysis patients who survive longer and the strengths of these risk factors for mortality change over time would assist physicians in making better prognostic judgments...
  75. ncbi request reprint Proteinuria and other markers of chronic kidney disease: a position statement of the national kidney foundation (NKF) and the national institute of diabetes and digestive and kidney diseases (NIDDK)
    Garabed Eknoyan
    Department of Medicine, Baylor College of Medicine, Houston, TX, USA
    Am J Kidney Dis 42:617-22. 2003
  76. ncbi request reprint Lipoprotein(a) and prevalent cardiovascular disease in a dialysis population: The Choices for Healthy Outcomes in Caring for ESRD (CHOICE) study
    J Craig Longenecker
    Johns Hopkins University, Baltimore, MD, USA
    Am J Kidney Dis 42:108-16. 2003
    ..We studied the association of Lp(a) level and apo(a) size with prevalent atherosclerotic cardiovascular disease (ASCVD) in 871 incident dialysis patients (261 blacks, 565 whites, 45 other)...
  77. ncbi request reprint Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention
    Mark J Sarnak
    Circulation 108:2154-69. 2003
  78. ncbi request reprint Chronic kidney disease: common, harmful, and treatable--World Kidney Day 2007
    Andrew S Levey
    Wake Forest University, School of Medicine, Medical Center Blvd, Winston Salem, NC 27157 1052, USA
    J Am Soc Nephrol 18:374-8. 2007
  79. ncbi request reprint Inflammation and inverse associations of body mass index and serum creatinine with mortality in hemodialysis patients
    Srinivasan Beddhu
    Veterans Affairs Salt Lake City Healthcare System, Salt Lake City, Utah 84112, USA
    J Ren Nutr 17:372-80. 2007
    ..Protein-energy wasting and inflammation are common and associated with an increased risk of mortality in hemodialysis (HD) patients. We examined the extent to which they mediate the associations of each other with death in this population...
  80. ncbi request reprint Calibration of serum creatinine in the National Health and Nutrition Examination Surveys (NHANES) 1988-1994, 1999-2004
    Elizabeth Selvin
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21287, USA
    Am J Kidney Dis 50:918-26. 2007
    ....
  81. ncbi request reprint Cerebrovascular disease in maintenance hemodialysis patients: results of the HEMO Study
    James A Delmez
    Washington University, St Louis, MO, USA
    Am J Kidney Dis 47:131-8. 2006
    ....
  82. ncbi request reprint Recommendations for improving serum creatinine measurement: a report from the Laboratory Working Group of the National Kidney Disease Education Program
    Gary L Myers
    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Clin Chem 52:5-18. 2006
    ..Available resources for standardization of serum creatinine measurement are discussed, and recommendations for measurement improvement are given...
  83. doi request reprint Serum cystatin C in the United States: the Third National Health and Nutrition Examination Survey (NHANES III)
    Anna Kottgen
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health and the Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Am J Kidney Dis 51:385-94. 2008
    ..However, information for serum cystatin C levels in the general population, specifically across a wide age range and different ethnicities, is lacking...
  84. pmc Agreement of self-reported comorbid conditions with medical and physician reports varied by disease among end-stage renal disease patients
    Sharon Stein Merkin
    Division of Geriatrics, Department of Medicine, Geffen School of Medicine, University of California Los Angeles, California, USA
    J Clin Epidemiol 60:634-42. 2007
    ..To compare self-report of eight diseases with review of medical records and physician reports...
  85. ncbi request reprint Clinical practice guidelines for chronic kidney disease in adults: Part II. Glomerular filtration rate, proteinuria, and other markers
    Cynda Ann Johnson
    Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA
    Am Fam Physician 70:1091-7. 2004
    ....
  86. doi request reprint CKD in the elderly--old questions and new challenges: World Kidney Day 2008
    Lesley A Stevens
    Am J Kidney Dis 51:353-7. 2008

Research Grants10

  1. Kidney Function, Aortic Stiffness and Aging
    Andrew S Levey; Fiscal Year: 2010
    ..This study will measure kidney function and stiffening of the aorta in a group of community dwelling older adults. ..
  2. Epidemiology, Clinical Trials, and Outcomes Research
    Andrew Levey; Fiscal Year: 2007
    ..To date, 50 applications have been received for 2005. Renewal of four training positions per year and addition of one position per year are requested for the next five years ..
  3. Chronic Renal Disease-Individual Patient Meta Analysis
    Andrew Levey; Fiscal Year: 2007
    ..The results will have a major impact on the care of patients with chronic kidney disease. ..
  4. CHRONIC RENAL DISEASE--INDIVIDUAL PATIENT META ANALYSIS
    Andrew Levey; Fiscal Year: 2001
    ..We believe the results will lead to improved outcomes for patients with chronic renal disease and more widespread application of individual patient data meta-analysis to translate findings from research into practice. ..
  5. Kidney Function, Aortic Stiffness and Aging
    Andrew S Levey; Fiscal Year: 2010
    ..This study will measure kidney function and stiffening of the aorta in a group of community dwelling older adults. ..