J Lau

Summary

Affiliation: Tufts-New England Medical Center
Country: USA

Publications

  1. ncbi Summing up evidence: one answer is not always enough
    J Lau
    Division of Clinical Care Research, New England Medical Center Hospitals, Boston, MA 02111, USA
    Lancet 351:123-7. 1998
  2. ncbi Diagnosing acute cardiac ischemia in the emergency department: a systematic review of the accuracy and clinical effect of current technologies
    J Lau
    Evidence Based Practice Center, Division of Clinical Care Research, New England Medical Center, Boston, MA 02111, USA
    Ann Emerg Med 37:453-60. 2001
  3. ncbi Accuracy of biomarkers to diagnose acute cardiac ischemia in the emergency department: a meta-analysis
    E M Balk
    Evidence-based Practice Center, Division of Clinical Care Research, New England Medical Center, Boston, MA 02115, USA
    Ann Emerg Med 37:478-94. 2001
  4. ncbi Accuracy of imaging technologies in the diagnosis of acute cardiac ischemia in the emergency department: a meta-analysis
    J P Ioannidis
    Evidence-based Practice Center, Division of Clinical Care Research, New England Medical Center, Boston, MA 02115, USA
    Ann Emerg Med 37:471-7. 2001
  5. ncbi Accuracy and clinical effect of out-of-hospital electrocardiography in the diagnosis of acute cardiac ischemia: a meta-analysis
    J P Ioannidis
    Evidence-based Practice Center, Division of Clinical Care Research, New England Medical Center, Boston, MA 02115, USA
    Ann Emerg Med 37:461-70. 2001
  6. ncbi Meta-analysis of diagnostic tests for acute sinusitis
    E A Engels
    Division of Clinical Care Research, Department of Medicine, New England Medical Center, Tufts University School of Medicine, 750 Washington Street, Boston, MA 02111, USA
    J Clin Epidemiol 53:852-62. 2000
  7. ncbi Evolution of treatment effects over time: empirical insight from recursive cumulative metaanalyses
    J Ioannidis
    Division of Clinical Care Research, New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Proc Natl Acad Sci U S A 98:831-6. 2001
  8. ncbi Balancing the benefits of primary angioplasty against the benefits of thrombolytic therapy for acute myocardial infarction: the importance of timing
    D M Kent
    New England Medical Center Tufts University School of Medicine, Boston, Mass, USA
    Eff Clin Pract 4:214-20. 2001
  9. ncbi Technical report: evidence for the diagnosis and treatment of acute uncomplicated sinusitis in children: a systematic overview
    J P Ioannidis
    New England Medical Center Evidence-based Practice Center, Boston, Massachusetts, USA
    Pediatrics 108:E57. 2001
  10. ncbi Comparison of evidence of treatment effects in randomized and nonrandomized studies
    J P Ioannidis
    Division of Clinical Care Research, New England Medical Center, Box 63, 750 Washington St, Boston, MA 02111, USA
    JAMA 286:821-30. 2001

Detail Information

Publications14

  1. ncbi Summing up evidence: one answer is not always enough
    J Lau
    Division of Clinical Care Research, New England Medical Center Hospitals, Boston, MA 02111, USA
    Lancet 351:123-7. 1998
    ..Here we take a more rounded approach to meta-analyses, arguing that their strengths outweigh their weaknesses, although the latter must not be brushed aside...
  2. ncbi Diagnosing acute cardiac ischemia in the emergency department: a systematic review of the accuracy and clinical effect of current technologies
    J Lau
    Evidence Based Practice Center, Division of Clinical Care Research, New England Medical Center, Boston, MA 02111, USA
    Ann Emerg Med 37:453-60. 2001
    ..Accurate diagnosis and triage of patients with ACI in the emergency department should increase survival for these patients and reduce unnecessary hospital admissions...
  3. ncbi Accuracy of biomarkers to diagnose acute cardiac ischemia in the emergency department: a meta-analysis
    E M Balk
    Evidence-based Practice Center, Division of Clinical Care Research, New England Medical Center, Boston, MA 02115, USA
    Ann Emerg Med 37:478-94. 2001
    ..Further high-quality studies are needed on the clinical effect of using biomarkers for patients with ACI in the ED and on optimal timing of serial testing and in combination with other tests...
  4. ncbi Accuracy of imaging technologies in the diagnosis of acute cardiac ischemia in the emergency department: a meta-analysis
    J P Ioannidis
    Evidence-based Practice Center, Division of Clinical Care Research, New England Medical Center, Boston, MA 02115, USA
    Ann Emerg Med 37:471-7. 2001
    ..More evidence should be accumulated on their performance specifically in the ED setting...
  5. ncbi Accuracy and clinical effect of out-of-hospital electrocardiography in the diagnosis of acute cardiac ischemia: a meta-analysis
    J P Ioannidis
    Evidence-based Practice Center, Division of Clinical Care Research, New England Medical Center, Boston, MA 02115, USA
    Ann Emerg Med 37:461-70. 2001
    ..Out-of-hospital thrombolysis achieves time savings and improves short-term mortality, but the effect on long-term mortality is unknown...
  6. ncbi Meta-analysis of diagnostic tests for acute sinusitis
    E A Engels
    Division of Clinical Care Research, Department of Medicine, New England Medical Center, Tufts University School of Medicine, 750 Washington Street, Boston, MA 02111, USA
    J Clin Epidemiol 53:852-62. 2000
    ..In conclusion, acute sinusitis is common among symptomatic patients. Radiography and clinical evaluation (especially risk scores) appear to provide useful information for diagnosis of sinusitis...
  7. ncbi Evolution of treatment effects over time: empirical insight from recursive cumulative metaanalyses
    J Ioannidis
    Division of Clinical Care Research, New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Proc Natl Acad Sci U S A 98:831-6. 2001
    ..Early wide oscillations in the evolution of the treatment effect for specific interventions may sometimes signal further major changes in the future...
  8. ncbi Balancing the benefits of primary angioplasty against the benefits of thrombolytic therapy for acute myocardial infarction: the importance of timing
    D M Kent
    New England Medical Center Tufts University School of Medicine, Boston, Mass, USA
    Eff Clin Pract 4:214-20. 2001
    ..However, fewer than 20% of U.S. hospitals have facilities to perform PTCA and many clinicians must choose between immediate thrombolytic therapy and delayed PTCA...
  9. ncbi Technical report: evidence for the diagnosis and treatment of acute uncomplicated sinusitis in children: a systematic overview
    J P Ioannidis
    New England Medical Center Evidence-based Practice Center, Boston, Massachusetts, USA
    Pediatrics 108:E57. 2001
    ..Diagnostic modalities show poor concordance, and treatment options are based on inadequate data. More evidence is needed for defining the optimal treatment and diagnostic methods for this common condition...
  10. ncbi Comparison of evidence of treatment effects in randomized and nonrandomized studies
    J P Ioannidis
    Division of Clinical Care Research, New England Medical Center, Box 63, 750 Washington St, Boston, MA 02111, USA
    JAMA 286:821-30. 2001
    ..There is substantial debate about whether the results of nonrandomized studies are consistent with the results of randomized controlled trials on the same topic...
  11. ncbi Efficacy of quinolone prophylaxis in neutropenic cancer patients: a meta-analysis
    E A Engels
    Tupper Research Institute, Department of Medicine, New England Medical Center, Boston, MA 02111, USA
    J Clin Oncol 16:1179-87. 1998
    ..To perform a meta-analysis to estimate the efficacy of quinolone antibiotics in preventing infections, fevers, and deaths among cancer patients neutropenic following chemotherapy...
  12. ncbi An empirical study of the effect of the control rate as a predictor of treatment efficacy in meta-analysis of clinical trials
    C H Schmid
    Department of Medicine, New England Medical Center, Boston, MA 02111, USA
    Stat Med 17:1923-42. 1998
    ....
  13. ncbi Effect of biocompatibility of hemodialysis membranes on mortality in acute renal failure: a meta-analysis
    B L Jaber
    Department of Medicine, New England Medical Center Hospitals, Boston, MA 02111, USA
    Clin Nephrol 57:274-82. 2002
    ....
  14. ncbi Grading evidence and recommendations for clinical practice guidelines in nephrology. A position statement from Kidney Disease: Improving Global Outcomes (KDIGO)
    K Uhlig
    Department of Medicine, Tufts New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Kidney Int 70:2058-65. 2006
    ..Further refinement of the system will be required for grading of evidence on questions other than those related to intervention effects, such as diagnostic accuracy and prognosis...