Research Topics
| Jeffrey KuvinSummaryAffiliation: Tufts-New England Medical Center Country: USA Publications
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Detail Information
Publications
High-density lipoprotein cholesterol-raising strategiesJeffrey T Kuvin
Division of Cardiology, Department of Medicine, Tufts New England Medical Center, Tufts University School of Medicine Boston, Massachusettes 0211, USA
J Cardiovasc Pharmacol 47:196-204. 2006..Recent findings regarding the role of HDL-C in cholesterol metabolism offer new strategies designed to target atherosclerosis. This review highlights the utility of existing HDL-C-raising strategies and examines new potential therapies...
Relation between high-density lipoprotein cholesterol and peripheral vasomotor functionJeffrey T Kuvin
Department of Medicine Division of Cardiology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
Am J Cardiol 92:275-9. 2003..These data suggest that impaired endothelial function associated with low HDL cholesterol may be an additional, previously unrecognized mechanism contributing to the increased risk of atherosclerosis in these patients...
Assessment of peripheral vascular endothelial function in the ambulatory settingJeffrey T Kuvin
Department of Medicine Division of Cardiology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
Vasc Med 12:13-6. 2007..In conclusion, these data suggest that peripheral vascular endothelial function testing is feasible in ambulatory patients, and this is an important next step in bringing this technology to clinical applicability...
Images in cardiovascular medicine. Primary lymphoma of the heartJeffrey Kuvin
Department of Medicine, Tufts-New England Medical Center, Tufts University School of Medicine, Boston, MA, USA
Circulation 112:e5-6. 2005
Comparison of flow-mediated dilatation of the brachial artery in coronary patients with low-density lipoprotein cholesterol levels <80 mg/dl versus patients with levels 80 to 100 mg/dlJeffrey T Kuvin
Division of Cardiology, Department of Medicine, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
Am J Cardiol 95:93-5. 2005..These data support recent reports that decreasing levels of LDL cholesterol below those currently recommended provides additional benefits and suggest that this benefit may be due in part to increased endothelial function...
Clinical utility of endothelial function testing: ready for prime time?Jeffrey T Kuvin
Division of Cardiology, Tufts New England Medical Center, 750 Washington St, Box 315, Boston, MA 02111, USA
Circulation 107:3243-7. 2003
Assessment of peripheral vascular endothelial function with finger arterial pulse wave amplitudeJeffrey T Kuvin
Department of Medicine, Division of Cardiology, Tufts New England Medical Center Hospitals, Tufts University School of Medicine, Boston, MA 02111, USA
Am Heart J 146:168-74. 2003..We evaluated the relationship between changes in PWA of the finger and peripheral endothelial function...
Effects of extended-release niacin on lipoprotein particle size, distribution, and inflammatory markers in patients with coronary artery diseaseJeffrey T Kuvin
The Division of Cardiology, Department of Medicine, Tufts New England Medical Center, Boston, Massachusetts, USA
Am J Cardiol 98:743-5. 2006..The effect of altering lipoprotein particle distribution and inflammatory markers on surrogate markers of atherosclerosis and clinical cardiovascular events in this population remains unclear...
Blood cyst of the mitral valve apparatus in a woman with a history of orthotopic liver transplantationJeffrey Kuvin
Division of Cardiology, Department of Medicine, Tufts New England Medical Center, Boston, MA 02111, USA
J Am Soc Echocardiogr 17:480-2. 2004..This case report highlights the use of echocardiography in diagnosing intracardiac blood cysts...
Assessor-blinded study of the metabolic syndrome and surrogate markers of increased cardiovascular risk in children with moderate-to-severe psoriasis compared with age-matched population of children with wartsEva M Volf
Tufts University School of Medicine, Boston, MA 02111, USA
J Drugs Dermatol 10:900-1. 2011..3 Here, we report the interim results of an ongoing study of MetS and CVD risk factors in pediatric psoriasis patients...
Evaluation of peripheral vascular endothelial function with a portable ultrasound deviceAlawi A Alsheikh-Ali
Division of Cardiology, Department of Medicine, Tufts-New England Medical Center Boston, Massachusetts 02111, USA
Echocardiography 23:623-6. 2006..These findings support the feasibility of noninvasive evaluation of peripheral endothelial function in the ambulatory setting...
Diet and exercise: are they worth it in the era of advanced pharmacotherapy?Jeffrey T Kuvin
J Cardiopulm Rehabil 26:294-6. 2006
Extent to which accepted serum lipid goals are achieved in a contemporary general medical population with coronary heart disease risk equivalentsAlawi A Alsheikh-Ali
Division of Cardiology and Molecular Cardiology Research Institute, Tufts-New England Medical Center and Tufts University School of Medicine, Boston, Massachusetts, USA
Am J Cardiol 98:1231-3. 2006..5% were taking fibrates and 8.2% niacin. In conclusion, the present analysis highlights the dramatic need to further improve preventive measures in a substantial proportion of high-risk patients with CHD risk equivalents...
Vascular endothelial dysfunction is associated with reversible myocardial perfusion defects in the absence of obstructive coronary artery diseasePrem Soman
Division of Cardiology, Tufts New England Medical Center, Boston, Mass, USA
J Nucl Cardiol 13:756-60. 2006..Recent evidence suggests that coronary endothelial dysfunction might play a role in the pathogenesis of these defects...
Association of estrogen receptor beta gene polymorphisms with left ventricular mass and wall thickness in womenInga Peter
Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
Am J Hypertens 18:1388-95. 2005..Given sex-based differences in cardiac structure and remodeling, we hypothesized that variation in estrogen pathway genes might be associated with alteration of LV structure...
Effect of soy protein from differently processed products on cardiovascular disease risk factors and vascular endothelial function in hypercholesterolemic subjectsNirupa R Matthan
Cardiovascular Nutrition Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
Am J Clin Nutr 85:960-6. 2007..The magnitude of the effect of soy protein on lipoprotein concentrations is variable. This discordance is likely attributable to the various forms of soy protein used and to unrecognized shifts in dietary fatty acid, cholesterol, and fiber...
Gender-based differences in brachial artery flow-mediated vasodilation as an indicator of significant coronary artery diseaseAyan R Patel
The Division of Cardiology, Department of Medicine, Tufts New England Medical Center, Boston, Massachusetts, USA
Am J Cardiol 96:1223-6. 2005..In studies using FMD to evaluate cardiovascular risk, different standards should be applied for women and men...
Peripheral vascular endothelial function correlates with exercise capacity in womenAyan R Patel
Division of Cardiology, Department of Medicine, Tufts New England Medical Center, Boston, MA 02111, USA
Clin Cardiol 28:433-6. 2005..These observations raise the possibility that the relationship between endothelial function and exercise capacity in women may differ from that in men...
Postoperative cardiac tamponade in the modern surgical eraJeffrey T Kuvin
Department of Medicine, Tufts New England Medical Center Hospitals, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
Ann Thorac Surg 74:1148-53. 2002..Females appear to be at higher risk for developing early postoperative CT. When diagnosed and treated promptly, postoperative CT should not significantly increase mortality...
Peripheral vascular endothelial function correlates with exercise capacity in cardiac transplant recipientsAyan R Patel
Division of Cardiology/Department of Medicine, Molecular Cardiology Research Institute, Tufts-New England Medical Center, Boston, Massachusetts 02111, USA
Am J Cardiol 91:897-9. 2003
Enhanced external counterpulsation improves endothelial function in patients with symptomatic coronary artery diseasePiero O Bonetti
Center for Coronary Physiology and Imaging and the Cardiac Catheterization Laboratory, Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
J Am Coll Cardiol 41:1761-8. 2003..This suggests that improvement in endothelial function may contribute to the clinical benefit of EECP in patients with symptomatic CAD...
The effects of LDL reduction and HDL augmentation on physiologic and inflammatory markersJeffrey T Kuvin
Department of Medicine, Tufts-New England Medical Center, Boston, Massachusetts 02111, USA
Curr Opin Cardiol 18:295-300. 2003..New therapeutic strategies are being designed to inhibit specific aspects of the inflammatory system that contribute to the initiation and progression of atherosclerosis...
High-density lipoprotein cholesterol and coronary heart diseaseChristine E Young
Department of Medicine/Division of Cardiology, Tufts-New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
Cardiol Rev 12:107-19. 2004..This review highlights the role of HDL in coronary heart disease, from basic mechanisms of action to recent clinical trial results...
A novel mechanism for the beneficial vascular effects of high-density lipoprotein cholesterol: enhanced vasorelaxation and increased endothelial nitric oxide synthase expressionJeffrey T Kuvin
Department of Medicine, New England Medical Center Hospitals, Inc, Tufts University School of Medicine, Boston, Mass, USA
Am Heart J 144:165-72. 2002....
Noninvasive identification of patients with early coronary atherosclerosis by assessment of digital reactive hyperemiaPiero O Bonetti
Center for Coronary Physiology and Imaging, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA
J Am Coll Cardiol 44:2137-41. 2004..CONCLUSIONS: Digital hyperemic response, as measured by RH-PAT, is attenuated in patients with coronary microvascular endothelial dysfunction, suggesting a role for RH-PAT as a noninvasive test to identify patients with this disorder...
Prevalence of low high-density lipoprotein cholesterol in patients with documented coronary heart disease or risk equivalent and controlled low-density lipoprotein cholesterolAlawi A Alsheikh Ali
Division of Cardiology and Molecular Cardiology Research Institute, Department of Medicine, Tufts New England Medical Center and Tufts University School of Medicine, Boston, Massachusetts, USA
Am J Cardiol 100:1499-501. 2007..In conclusion, in high-risk patients with CHD or CHD risk equivalents, low HDL cholesterol levels remain prevalent despite statin treatment and the achievement of aggressive LDL cholesterol goals...
Present-day uses of niacin: effects on lipid and non-lipid parametersSanjukta Sanyal
Tufts New England Medical Center, Department of Medicine, Division of Cardiology, Boston, Massachusetts 02111, USA
Expert Opin Pharmacother 8:1711-7. 2007..Niacin has the promise of being a powerful pharmacologic agent in the fight against atherosclerotic disease, although additional clinical studies are required to examine this further...
High-density lipoprotein cholesterol in the cardiovascular equation: does the "good" still count?Alawi A Alsheikh-Ali
Molecular Cardiology Research Institute, Division of Cardiology, Tufts New England Medical Center, Tufts University School of Medicine, 750 Washington Street, Box 80, Boston, MA 02111, USA
Atherosclerosis 180:217-23. 2005....
Effect of short-term antibiotic treatment on Chlamydia pneumoniae and peripheral endothelial functionJeffrey T Kuvin
Division of Cardiology, Department of Medicine, Tufts-New England Medical Center, Boston, Massachusetts, USA
Am J Cardiol 91:732-5. 2003
Uncorrected tetralogy of Fallot in an 86-year-old patientAlvaro Alonso
Department of Medicine, Division of Cardiology, Cardiovascular Imaging and Hemodynamic Laboratory, Tufts New England Medical Center, Boston, MA 02111, USA
Am J Geriatr Cardiol 16:38-41. 2007..After a systematic literature search, the authors believe this case represents the oldest reported patient with the diagnosis of uncorrected tetralogy of Fallot and serves as an example of a well-balanced congenital shunt...
Echocardiographic detection of intrapulmonary shunting in a patient with hepatopulmonary syndrome: case report and review of the literatureRichard Pacca
Division of Cardiology, Department of Medicine, Tufts-New England Medical Center, Boston, Massachusetts 02111, USA
Echocardiography 23:56-9. 2006..This case report highlights the utility of echocardiography in diagnosing intrapulmonary shunts and assists in the understanding of the pathophysiology of hypoxemia in such patients...
Left ventricular remodelling index (LVRI) in various pathophysiological conditions: a real-time three-dimensional echocardiographic studyStefano De Castro
Department of Cardiovascular, Respiratory and Morphological Sciences, La Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy
Heart 93:205-9. 2007..Various studies have reported a close correlation between real-time three-dimensional echocardiography (RT3DE) and cine magnetic resonance imaging studies for the assessment of cardiac volumes and mass...
Risk of adverse events with fibratesAlawi A Alsheikh-Ali
Molecular Cardiology Research Institute, Department of Medicine, Division of Cardiology, Tufts-New England Medical Center and Tufts University School of Medicine, Boston, Massachusetts 02111, USA
Am J Cardiol 94:935-8. 2004..This difference was especially noticeable in patients taking the combination of gemfibrozil and a statin, particularly cerivastatin...
