Patricia L Hibberd

Summary

Affiliation: Tufts-New England Medical Center
Country: USA

Publications

  1. ncbi request reprint Monitoring participant safety in phase I and II interventional trials: options and controversies
    Patricia L Hibberd
    Division of Clinical Research Resources, Tufts New England Medical Center 35 Kneeland Street, Box 063, Boston, MA 02111, USA
    J Investig Med 52:446-52. 2004
  2. ncbi request reprint Challenges in the design of antibiotic equivalency studies: the multicenter equivalency study of oral amoxicillin versus injectable penicillin in children aged 3-59 months with severe pneumonia
    Patricia L Hibberd
    Clinical Research Institute and Health Policy Studies, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Clin Infect Dis 39:526-31. 2004
  3. pmc Tai Chi is effective in treating knee osteoarthritis: a randomized controlled trial
    Chenchen Wang
    Division of Rheumatology, Tufts Medical Center, Box 406, Tufts University School of Medicine, Boston, MA 02111, USA
    Arthritis Rheum 61:1545-53. 2009
  4. pmc Systemic antibody responses to the immunodominant p23 antigen and p23 polymorphisms in children with cryptosporidiosis in Bangladesh
    Anoli J Borad
    Division of Geographic Medicine and Infectious Disease, Tufts Medical Center, Boston, Massachusetts 02111, USA
    Am J Trop Med Hyg 86:214-22. 2012
  5. ncbi request reprint Illness transmission in the home: a possible role for alcohol-based hand gels
    Grace M Lee
    Center for Child Health Care Studies, Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care and Harvard Medical School, Boston, Massachusetts 02215, USA
    Pediatrics 115:852-60. 2005
  6. ncbi request reprint Preliminary assessment of inhaled nitric oxide for acute vaso-occlusive crisis in pediatric patients with sickle cell disease
    Debra L Weiner
    Pediatric Emergency, Children s Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
    JAMA 289:1136-42. 2003
  7. ncbi request reprint Hepatic steatosis is associated with fibrosis, nucleoside analogue use, and hepatitis C virus genotype 3 infection in HIV-seropositive patients
    Barbara H McGovern
    HIV HCV Co infection Clinic, Lemuel Shattuck Hospital, Jamaica Plain, Jamaica Plain, MA 02494, USA
    Clin Infect Dis 43:365-72. 2006
  8. ncbi request reprint Misconceptions about colds and predictors of health service utilization
    Grace M Lee
    Division of Infectious Diseases, Children s Hospital, Boston, Massachusetts 02115, USA
    Pediatrics 111:231-6. 2003
  9. pmc Tai Chi for treating knee osteoarthritis: designing a long-term follow up randomized controlled trial
    Chenchen Wang
    Division of Rheumatology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA
    BMC Musculoskelet Disord 9:108. 2008
  10. pmc Antibody responses to the immunodominant Cryptosporidium gp15 antigen and gp15 polymorphisms in a case-control study of cryptosporidiosis in children in Bangladesh
    Genève M Allison
    Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center and Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Am J Trop Med Hyg 85:97-104. 2011

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Monitoring participant safety in phase I and II interventional trials: options and controversies
    Patricia L Hibberd
    Division of Clinical Research Resources, Tufts New England Medical Center 35 Kneeland Street, Box 063, Boston, MA 02111, USA
    J Investig Med 52:446-52. 2004
    ..However, there is little guidance about when and how to constitute a DSMB for phase I and II clinical trials...
  2. ncbi request reprint Challenges in the design of antibiotic equivalency studies: the multicenter equivalency study of oral amoxicillin versus injectable penicillin in children aged 3-59 months with severe pneumonia
    Patricia L Hibberd
    Clinical Research Institute and Health Policy Studies, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Clin Infect Dis 39:526-31. 2004
    ..These considerations have implications for use of the Amoxicillin Penicillin Pneumonia International Study (APPIS) results in clinical practice and for potential modification of WHO treatment guidelines...
  3. pmc Tai Chi is effective in treating knee osteoarthritis: a randomized controlled trial
    Chenchen Wang
    Division of Rheumatology, Tufts Medical Center, Box 406, Tufts University School of Medicine, Boston, MA 02111, USA
    Arthritis Rheum 61:1545-53. 2009
    ..To evaluate the effectiveness of Tai Chi in the treatment of knee osteoarthritis (OA) symptoms...
  4. pmc Systemic antibody responses to the immunodominant p23 antigen and p23 polymorphisms in children with cryptosporidiosis in Bangladesh
    Anoli J Borad
    Division of Geographic Medicine and Infectious Disease, Tufts Medical Center, Boston, Massachusetts 02111, USA
    Am J Trop Med Hyg 86:214-22. 2012
    ..Although most children were infected with Cryptosporidium hominis, there was a cross-reactive antibody response to C. parvum antigen. These results support further development of p23 as a vaccine candidate...
  5. ncbi request reprint Illness transmission in the home: a possible role for alcohol-based hand gels
    Grace M Lee
    Center for Child Health Care Studies, Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care and Harvard Medical School, Boston, Massachusetts 02215, USA
    Pediatrics 115:852-60. 2005
    ..We also sought to examine potential predictors of reduced illness transmission in the home in a secondary analysis...
  6. ncbi request reprint Preliminary assessment of inhaled nitric oxide for acute vaso-occlusive crisis in pediatric patients with sickle cell disease
    Debra L Weiner
    Pediatric Emergency, Children s Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
    JAMA 289:1136-42. 2003
    ..Nitric oxide may have promise as a mechanism-of-disease-based therapy for treatment of vaso-occlusion...
  7. ncbi request reprint Hepatic steatosis is associated with fibrosis, nucleoside analogue use, and hepatitis C virus genotype 3 infection in HIV-seropositive patients
    Barbara H McGovern
    HIV HCV Co infection Clinic, Lemuel Shattuck Hospital, Jamaica Plain, Jamaica Plain, MA 02494, USA
    Clin Infect Dis 43:365-72. 2006
    ....
  8. ncbi request reprint Misconceptions about colds and predictors of health service utilization
    Grace M Lee
    Division of Infectious Diseases, Children s Hospital, Boston, Massachusetts 02115, USA
    Pediatrics 111:231-6. 2003
    ..The objective of this study was to determine predictors of reported ED use and ambulatory care use for colds among families with young children...
  9. pmc Tai Chi for treating knee osteoarthritis: designing a long-term follow up randomized controlled trial
    Chenchen Wang
    Division of Rheumatology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA
    BMC Musculoskelet Disord 9:108. 2008
    ..The study will be completed by July 2009...
  10. pmc Antibody responses to the immunodominant Cryptosporidium gp15 antigen and gp15 polymorphisms in a case-control study of cryptosporidiosis in children in Bangladesh
    Genève M Allison
    Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center and Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Am J Trop Med Hyg 85:97-104. 2011
    ..These findings support further investigation of gp15 as a vaccine candidate...
  11. pmc Open-label, dose escalation phase I study in healthy volunteers to evaluate the safety and pharmacokinetics of a human monoclonal antibody to Clostridium difficile toxin A
    Claribel P Taylor
    Beth Israel Deaconess Medical Center, University of Massachusetts Medical School, Boston, Massachusetts, USA
    Vaccine 26:3404-9. 2008
    ..difficile toxin A are protective against symptomatic disease and recurrence. We examined the safety and pharmacokinetics (pk) of a novel neutralizing human monoclonal antibody against C. difficile toxin A (CDA1) in healthy adults...
  12. doi request reprint Stress management versus lifestyle modification on systolic hypertension and medication elimination: a randomized trial
    Jeffery A Dusek
    Benson Henry Institute for Mind Body Medicine at Massachusetts General Hospital, Boston, MA 02114, USA
    J Altern Complement Med 14:129-38. 2008
    ..2-15.9, p=0.03). Although both groups had similar reductions in SBP, significantly more participants in the relaxation response group eliminated an antihypertensive medication while maintaining adequate blood pressure control...
  13. doi request reprint Probiotic foods and drugs: impact of US regulatory status on design of clinical trials
    Patricia L Hibberd
    Department of Geographic Medicine and Infectious Diseases, Tufts New England Medical Center, and 2Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Clin Infect Dis 46:S137-40; discussion S144-51. 2008
    ....
  14. ncbi request reprint The effect of a selective cyclooxygenase-2 inhibitor (celecoxib) on chronic periodontitis
    C Alec Yen
    Department of Oral Medicine, Tufts University School of Dental Medicine, Boston, MA 02111, USA
    J Periodontol 79:104-13. 2008
    ..In this double-masked, placebo-controlled, randomized clinical trial, the efficacy of celecoxib (COX-2 inhibitor) was evaluated in conjunction with scaling and root planing (SRP) in subjects with chronic periodontitis (CP)...
  15. ncbi request reprint Probiotics for prevention of antibiotic-associated diarrhea
    Shira Idit Doron
    Division of Geographic Medicine and Infectious Diseases, Tufts New England Medical Center, Boston, MA, USA
    J Clin Gastroenterol 42:S58-63. 2008
    ..Probiotics are generally safe, however, they should be used with caution in patients who have compromise of either the immune system or the integrity of the intestinal mucosa, and in the presence of a central venous catheter...
  16. ncbi request reprint Computerized recruiting for clinical trials in real time
    Debra L Weiner
    Division of Emergency Medicine, the Children s Hospital Informatics Program, Children s Hospital Boston, Boston, MA, USA
    Ann Emerg Med 41:242-6. 2003
    ..We hypothesize that the automated notification system improves the rate of investigator notification...
  17. pmc Clinical trial design--effect of prone positioning on clinical outcomes in infants and children with acute respiratory distress syndrome
    Martha A Q Curley
    Critical Care and Cardiovascular Nursing, Children s Hospital, Boston, MA 02115, USA
    J Crit Care 21:23-32; discussion 32-7. 2006
    ..It is not known if these improvements in oxygenation result in improvements in clinical outcomes. A clinical trial was needed to answer this question...
  18. ncbi request reprint Resource utilization among patients with sepsis syndrome
    David W Bates
    Division of General Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Infect Control Hosp Epidemiol 24:62-70. 2003
    ..To assess the resource utilization associated with sepsis syndrome in academic medical centers...
  19. ncbi request reprint Relationship of pulmonary artery catheter use to mortality and resource utilization in patients with severe sepsis
    D Tony Yu
    Division of General Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Crit Care Med 31:2734-41. 2003
    ..To examine the relationship of pulmonary artery catheter (PAC) use to patient outcomes, including mortality rate and resource utilization, in patients with severe sepsis in eight academic medical centers...
  20. ncbi request reprint Study of the Therapeutic Effects of Intercessory Prayer (STEP) in cardiac bypass patients: a multicenter randomized trial of uncertainty and certainty of receiving intercessory prayer
    Herbert Benson
    Mind Body Medical Institute, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Am Heart J 151:934-42. 2006
    ..We evaluated whether (1) receiving intercessory prayer or (2) being certain of receiving intercessory prayer was associated with uncomplicated recovery after coronary artery bypass graft (CABG) surgery...
  21. ncbi request reprint A randomized, double-blind trial of Lactobacillus GG versus placebo in addition to standard maintenance therapy for children with Crohn's disease
    Athos Bousvaros
    Division of Pediatric Gastroenterology, Children s Hospital, Boston, Massachusetts 02115, USA
    Inflamm Bowel Dis 11:833-9. 2005
    ..18). The LGG was well tolerated, with a side effect profile comparable with placebo. This study suggests that LGG does not prolong time to relapse in children with CD when given as an adjunct to standard therapy...
  22. ncbi request reprint Association between oxygen consumption and nitric oxide production during the relaxation response
    Jeffery A Dusek
    Mind Body Medical Institute, 824 Boylston Street, Chestnut Hill, MA 02467, USA
    Med Sci Monit 12:CR1-10. 2006
    ..We evaluated whether depth of RR elicitation was correlated with changes in NO, as measured by percentage changes in fractional exhaled nitric oxide (F(E)NO)...
  23. ncbi request reprint Healing prayer outcomes studies: consensus recommendations
    Jeffery A Dusek
    Mind Body Medical Institute, Chestnut Hill, Mass, USA
    Altern Ther Health Med 9:A44-53. 2003
  24. doi request reprint Executive summary: scientific and regulatory challenges of development of probiotics as foods and drugs
    Freddie Ann Hoffman
    HeteroGeneity, Washington, DC 20011, USA
    Clin Infect Dis 46:S53-7. 2008
  25. ncbi request reprint Cryptosporidiosis among Bangladeshi children with diarrhea: a prospective, matched, case-control study of clinical features, epidemiology and systemic antibody responses
    Wasif A Khan
    Clinical Sciences Division, Centre for Health and Population Research, International Center for Diarrheal Disease Research, Bangladesh, Dhaka, Bangladesh, GPO Box 128, Dhaka 1000, Bangladesh
    Am J Trop Med Hyg 71:412-9. 2004
    ..However, there was a significant difference between children with acute and persistent diarrhea in changes in both IgA and IgM levels, with persistent diarrhea being associated with a decrease in levels of both antibodies...