Olaf Dammann

Summary

Affiliation: Tufts-New England Medical Center
Country: USA

Publications

  1. doi The clustering of disorders in infants born before the 28th week of gestation
    Alan Leviton
    Neurology Department, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
    Acta Paediatr 99:1795-800. 2010
  2. ncbi Happiness reconsidered in children with cerebral palsy
    Olaf Dammann
    Department of Pediatrics, Tufts New England Medical Center, Boston, MA, USA
    Lancet 369:2137-8. 2007
  3. pmc Neuregulin-1: a potential endogenous protector in perinatal brain white matter damage
    Olaf Dammann
    Division of Newborn Medicine, Department of Pediatrics, Tufts New England Medical Center, Boston, Mass, USA
    Neonatology 93:182-7. 2008
  4. ncbi Perinatal brain damage causation
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, OE 6415, Hannover Medical School, Hannover, Germany
    Dev Neurosci 29:280-8. 2007
  5. pmc SNAP-II and SNAPPE-II and the risk of structural and functional brain disorders in extremely low gestational age newborns: the ELGAN study
    Olaf Dammann
    Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Boston, Mass 02111, USA
    Neonatology 97:71-82. 2010
  6. pmc Neuregulin-1, the fetal endothelium, and brain damage in preterm newborns
    Insa Hoffmann
    Pediatric Pulmonology and Neonatology, Hannover Medical School, Hannover, Germany
    Brain Behav Immun 24:784-91. 2010
  7. pmc Inflammation-initiating illnesses, inflammation-related proteins, and cognitive impairment in extremely preterm infants
    T MICHAEL O'SHEA
    Division of Neonatology, Department of Pediatrics, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Brain Behav Immun 29:104-12. 2013
  8. ncbi Is maternal obesity associated with sustained inflammation in extremely low gestational age newborns?
    Jelske W van der Burg
    Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, United States Department of Health Sciences and the EMGO Institute for Health and Care Research, VU University Amsterdam, Amsterdam, The Netherlands
    Early Hum Dev 89:949-55. 2013
  9. doi Immaturity, perinatal inflammation, and retinopathy of prematurity: a multi-hit hypothesis
    Olaf Dammann
    Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Boston, MA 02111, USA
    Early Hum Dev 85:325-9. 2009
  10. doi Neuregulin-1 high-producer genotype is associated with a decreased risk of admission to the neonatal intensive care unit
    Elizabeth P Pleickhardt
    Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Boston, MA 02111, USA
    Early Hum Dev 86:299-304. 2010

Detail Information

Publications80

  1. doi The clustering of disorders in infants born before the 28th week of gestation
    Alan Leviton
    Neurology Department, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
    Acta Paediatr 99:1795-800. 2010
    ..To see whether disorders prevalent in infants born extremely preterm cluster...
  2. ncbi Happiness reconsidered in children with cerebral palsy
    Olaf Dammann
    Department of Pediatrics, Tufts New England Medical Center, Boston, MA, USA
    Lancet 369:2137-8. 2007
  3. pmc Neuregulin-1: a potential endogenous protector in perinatal brain white matter damage
    Olaf Dammann
    Division of Newborn Medicine, Department of Pediatrics, Tufts New England Medical Center, Boston, Mass, USA
    Neonatology 93:182-7. 2008
    ..We outline how NRG-1 might be involved in perinatal brain damage pathomechanisms and suggest that NRG-1 might be one target for intervention...
  4. ncbi Perinatal brain damage causation
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, OE 6415, Hannover Medical School, Hannover, Germany
    Dev Neurosci 29:280-8. 2007
    ..We hope that our critical discussion will contribute to fruitful research and help reduce the burden of perinatal brain damage...
  5. pmc SNAP-II and SNAPPE-II and the risk of structural and functional brain disorders in extremely low gestational age newborns: the ELGAN study
    Olaf Dammann
    Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Boston, Mass 02111, USA
    Neonatology 97:71-82. 2010
    ..Illness severity measures predict death and illnesses in the newborn. It is unknown how well they predict brain lesions evident on ultrasound scans or neurodevelopmental dysfunctions in preterm infants...
  6. pmc Neuregulin-1, the fetal endothelium, and brain damage in preterm newborns
    Insa Hoffmann
    Pediatric Pulmonology and Neonatology, Hannover Medical School, Hannover, Germany
    Brain Behav Immun 24:784-91. 2010
    ..To assess the potential role for Neuregulin-1 (NRG1) as a systemic endogenous protector in the setting of perinatal inflammatory brain damage...
  7. pmc Inflammation-initiating illnesses, inflammation-related proteins, and cognitive impairment in extremely preterm infants
    T MICHAEL O'SHEA
    Division of Neonatology, Department of Pediatrics, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Brain Behav Immun 29:104-12. 2013
    ..We conclude that elevated blood concentrations of inflammation-related proteins provide information about the risk of impaired cognitive function at age 2 years that supplements information provided by inflammation-associated illnesses...
  8. ncbi Is maternal obesity associated with sustained inflammation in extremely low gestational age newborns?
    Jelske W van der Burg
    Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, United States Department of Health Sciences and the EMGO Institute for Health and Care Research, VU University Amsterdam, Amsterdam, The Netherlands
    Early Hum Dev 89:949-55. 2013
    ..The offspring of obese women are at increased risk for systemic inflammation. Blood concentrations of inflammatory proteins in preterm newborns of obese women have not been reported...
  9. doi Immaturity, perinatal inflammation, and retinopathy of prematurity: a multi-hit hypothesis
    Olaf Dammann
    Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Boston, MA 02111, USA
    Early Hum Dev 85:325-9. 2009
    ..To explore the relationship among markers of infection/inflammation in their association with retinopathy of prematurity (ROP)...
  10. doi Neuregulin-1 high-producer genotype is associated with a decreased risk of admission to the neonatal intensive care unit
    Elizabeth P Pleickhardt
    Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Boston, MA 02111, USA
    Early Hum Dev 86:299-304. 2010
    ..Neuregulin (NRG1) is a developmental growth factor and homozygous C allele carriers at the NRG221533 locus are at reduced risk for developmental disability...
  11. doi Maternal obesity, gestational hypertension, and preterm delivery
    Juliette Madan
    Division of Neonatology, Department of Pediatrics, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    J Matern Fetal Neonatal Med 23:82-8. 2010
    ..To study maternal obesity as a risk factor for preterm delivery...
  12. doi Does bronchopulmonary dysplasia contribute to the occurrence of cerebral palsy among infants born before 28 weeks of gestation?
    Linda J Van Marter
    Newborn Medicine, Children s Hospital, 300 Longwood Avenue, Boston, MA 02115, USA
    Arch Dis Child Fetal Neonatal Ed 96:F20-9. 2011
    ..To evaluate the relationships among cerebral palsy (CP) phenotypes and bronchopulmonary dysplasia (BPD) severity and, in the process, to generate hypotheses regarding causal pathways linking BPD to CP...
  13. ncbi Systemic inflammation, intraventricular hemorrhage, and white matter injury
    Alan Leviton
    1Department of Neurology, Children s Hospital, Boston, MA, USA
    J Child Neurol 28:1637-45. 2013
    ..Each entity is associated with inflammation, but the combination has a stronger inflammatory signal than hemorrhage alone. ..
  14. pmc Elevated concentrations of inflammation-related proteins in postnatal blood predict severe developmental delay at 2 years of age in extremely preterm infants
    T MICHAEL O'SHEA
    Department of Pediatrics, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Pediatr 160:395-401.e4. 2012
    ..To evaluate the hypothesis that elevated levels of inflammation-related proteins in early postnatal blood predict impaired mental and motor development in extremely preterm infants...
  15. pmc Cranial ultrasound lesions in the NICU predict cerebral palsy at age 2 years in children born at extremely low gestational age
    Karl C K Kuban
    Division of Pediatric Neurology, Department of Pediatrics, Boston Medical Center, Boston University, Boston, Massachusetts, USA
    J Child Neurol 24:63-72. 2009
    ..Nearly half the cerebral palsy identified at 2 years is not preceded by a neonatal brain ultrasound abnormality...
  16. doi The relationship between early concentrations of 25 blood proteins and cerebral white matter injury in preterm newborns: the ELGAN study
    Alan Leviton
    Neuroepidemiology Unit, Department of Neurology, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
    J Pediatr 158:897-903.e1-5. 2011
    ..To evaluate whether concentrations of inflammation-related proteins are elevated in the blood of preterm newborns who develop cerebral white matter damage...
  17. pmc Patterns of blood protein concentrations of ELGANs classified by three patterns of respiratory disease in the first 2 postnatal weeks
    Matthew Laughon
    Department of Pediatrics, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Pediatr Res 70:292-6. 2011
    ..Inflammation might influence the risk of EPPD and PD or be a consequence of lung damage or therapies to minimize lung dysfunction...
  18. doi Persistence after birth of systemic inflammation associated with umbilical cord inflammation
    Alan Leviton
    Department of Neurology, Children s Hospital Boston and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    J Reprod Immunol 90:235-43. 2011
    ....
  19. doi Blood protein concentrations in the first two postnatal weeks associated with early postnatal blood gas derangements among infants born before the 28th week of gestation. The ELGAN Study
    Alan Leviton
    Department of Neurology, Children s Hospital Boston, and Harvard Medical School, Boston, MA 02115, USA
    Cytokine 56:392-8. 2011
    ..To explore the relationships between blood gas derangements and blood concentrations of inflammation-related proteins shortly after preterm birth...
  20. ncbi Nijmegen Breakage Syndrome mutations and risk of breast cancer
    Natalia Bogdanova
    Gynecology Research Unit, Hannover Medical School, Hannover, Germany
    Int J Cancer 122:802-6. 2008
    ..1; 95%CI 1.4-6.6) and indicate that the 657del5 deletion and perhaps the R215W substitution contribute to inherited breast cancer susceptibility in Central and Eastern Europe...
  21. pmc Cluster analysis of placental inflammatory proteins can distinguish preeclampsia from preterm labor and premature membrane rupture in singleton deliveries less than 28 weeks of gestation
    Jessica M Faupel-Badger
    Cancer Prevention Fellowship Program, National Cancer Institute, Bethesda, MD 20892 7105, USA
    Am J Reprod Immunol 66:488-94. 2011
    ..The risks of complications are different between iatrogenic (e.g. PE) and spontaneous (e.g. PL and membrane rupture) causes of preterm delivery, suggesting different underlying biology contributes to these placental conditions...
  22. pmc Interinstitutional variation in prediction of death by SNAP-II and SNAPPE-II among extremely preterm infants
    Olaf Dammann
    Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Boston, Massachusetts 02111, USA
    Pediatrics 124:e1001-6. 2009
    ..Illness severity scores predict death among infants admitted to NICUs. We know of no study limited to a population defined by an extremely low gestational age...
  23. pmc Neonatal cranial ultrasound lesions and developmental delays at 2 years of age among extremely low gestational age children
    T MICHAEL O'SHEA
    Wake Forest University Health Sciences, Department of Pediatrics, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Pediatrics 122:e662-9. 2008
    ..Studies of the relationship between ultrasound images from preterm newborns and developmental delay most often are based on small samples defined by birth weight and exclude infants not testable with standardized assessments...
  24. pmc Neurodevelopment of extremely preterm infants who had necrotizing enterocolitis with or without late bacteremia
    Camilia R Martin
    Department of Neonatology, Beth Israel Deaconess Medical Center, Harvard University, Boston, MA, USA
    J Pediatr 157:751-6.e1. 2010
    ..To evaluate neurodevelopment after necrotizing enterocolitis (NEC) and late bacteremia, alone and together...
  25. pmc Early blood gas abnormalities and the preterm brain
    Alan Leviton
    Neuroepidemiology Unit, Neurology Department, Children s Hospital Boston, and Harvard Medical School, Boston, Massachusetts 02215 5724, USA
    Am J Epidemiol 172:907-16. 2010
    ..Findings suggest that individual blood gas derangements do not increase brain damage risk. Rather, the multiple derangements associated with indicators of brain damage might be indicators of immaturity/vulnerability and illness severity...
  26. doi Neonatal bacteremia and retinopathy of prematurity: the ELGAN study
    Kristi Washburn Tolsma
    Division of Newborn Medicine, Floating Hospital for Children, Tufts Medical Center, 800 Washington St, PO Box 854, Boston, MA 02111 1526, USA
    Arch Ophthalmol 129:1555-63. 2011
    ..To explore whether early or late and presumed or definite neonatal bacteremia are associated with an increased risk of severe retinopathy of prematurity (ROP)...
  27. ncbi Inflammatory brain damage in preterm newborns--dry numbers, wet lab, and causal inferences
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, Hannover Medical School, Germany
    Early Hum Dev 79:1-15. 2004
    ..We also need more (and more detailed) observational studies clarifying the presumed infection --> inflammation --> WMD sequence before we can initiate intervention trials to reduce the risk of WMD...
  28. ncbi Lung and brain damage in preterm newborns. Are they related? How? Why?
    Olaf Dammann
    Departments of Obstetrics and Pediatrics, Perinatal Infectious Disease Epidemiology Unit, Hannover Medical School, Hannover, Germany
    Biol Neonate 85:305-13. 2004
    ..g. postnatal steroid exposure) that increase the risk for developmental disability in childhood...
  29. doi Pregnancy disorders appear to modify the risk for retinopathy of prematurity associated with neonatal hyperoxemia and bacteremia
    Jennifer W Lee
    Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Boston, MA 02111, USA
    J Matern Fetal Neonatal Med 26:811-8. 2013
    ....
  30. pmc Two-hit model of brain damage in the very preterm newborn: small for gestational age and postnatal systemic inflammation
    Alan Leviton
    Department of Neurology, Boston Children s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Pediatr Res 73:362-70. 2013
    ..We sought to disentangle the contributions of perinatal systemic inflammation and being small for gestational age (SGA) to the occurrence of low Bayley Mental Development Indices (MDIs) at the age of 2 y...
  31. pmc Placenta microbiology and histology and the risk for severe retinopathy of prematurity
    Minghua L Chen
    Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Boston, Massachusetts 02111 1526, USA
    Invest Ophthalmol Vis Sci 52:7052-8. 2011
    ..To test the hypothesis that the presence of bacteria and/or histologic inflammation in the placenta of infants born preterm is associated with an increased risk for severe retinopathy of prematurity (ROP)...
  32. pmc Infection, oxygen, and immaturity: interacting risk factors for retinopathy of prematurity
    Minghua Chen
    Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Boston, MA 02111 1526, USA
    Neonatology 99:125-32. 2011
    ..Interactions among known risk factors for retinopathy of prematurity (ROP) remain to be clarified...
  33. ncbi Lung and brain damage in preterm newborns, and their association with gestational age, prematurity subgroup, infection/inflammation and long term outcome
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, Department of Obstetrics and Pediatrics, OE 6415 Hannover Medical School, 30623 Hannover, Germany
    BJOG 112:4-9. 2005
    ..In this paper we discuss the complexities that paediatricians, perinatologists and perinatal epidemiologists face as they try to understand the contributions of factors associated with preterm birth to neonatal and childhood disorders...
  34. pmc Fetal growth restriction and chronic lung disease among infants born before the 28th week of gestation
    Carl Bose
    Department of Pediatrics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Pediatrics 124:e450-8. 2009
    ..There is now increasing interest in exposures and events before delivery that predict CLD. The objective of this study was to identify current prenatal predictors of CLD...
  35. ncbi Bronchopulmonary dysplasia is not associated with ultrasound-defined cerebral white matter damage in preterm newborns
    Olaf Dammann
    Department of Obstetrics, Prenatal Medicine and Gynecology, Hannover Medical School, 30623 Hannover, Germany
    Pediatr Res 55:319-25. 2004
    ..Confounding does not seem to account for this lack of association between WMD and BPD. In conclusion, our findings do not support the hypothesis that BPD contributes to the occurrence of sonographically defined WMD...
  36. ncbi Chorioamnionitis, mechanical ventilation, and postnatal sepsis as modulators of chronic lung disease in preterm infants
    Linda J Van Marter
    Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    J Pediatr 140:171-6. 2002
    ..This case-control study of chronic lung disease (CLD) evaluated the hypothesis that chorioamnionitis promotes CLD and interacts with other risk factors for CLD, including mechanical ventilation and postnatal infection...
  37. pmc Endoplasmic reticulum stress, inflammation, and perinatal brain damage
    Wolfgang Bueter
    Perinatal Neuroepidemiology Unit OE 6415, Departments of Obstetrics and Pediatrics, Hannover Medical School, Hannover, Germany
    Pediatr Res 66:487-94. 2009
    ..Perhaps by these events, noninflammatory stimuli lead to perinatal brain damage...
  38. ncbi Antenatal mycoplasma infection, the fetal inflammatory response and cerebral white matter damage in very-low-birthweight infants
    Olaf Dammann
    Hannover Medical School, Germany
    Paediatr Perinat Epidemiol 17:49-57. 2003
    ..Our finding that M. hominis in the placenta was associated with a not quite significant threefold risk increase for echolucency deserves further investigation...
  39. pmc Inflammation-related proteins in the blood of extremely low gestational age newborns. The contribution of inflammation to the appearance of developmental regulation
    Alan Leviton
    Neurology Department, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
    Cytokine 53:66-73. 2011
    ..We wanted to assess to what extent concentrations of circulating proteins appear to be developmentally regulated, and to what extent such regulation is influenced by intra-uterine inflammation...
  40. pmc Early nutrition and weight gain in preterm newborns and the risk of retinopathy of prematurity
    Deborah K Vanderveen
    Department of Ophthalmology, Boston Children s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    PLoS ONE 8:e64325. 2013
    ..To identify nutritional and weight gain limitations associated with retinopathy of prematurity (ROP) severity among very preterm newborns...
  41. pmc Systemic responses of preterm newborns with presumed or documented bacteraemia
    Alan Leviton
    Department of Neurology, Children s Hospital Boston, and Harvard Medical School, Boston, MA 02215 5349, USA
    Acta Paediatr 101:355-9. 2012
    ....
  42. ncbi NEUROBID--an EU-funded project to study the developing brain barriers
    Wolfgang Bueter
    Hannover Medical School, Hannover, Germany
    Int J Dev Neurosci 28:411-2. 2010
    ..In the long term, NEUROBID hopes to pave the way for new treatment strategies and thus reduce the economic and social burden of neurological disease...
  43. ncbi Inflammation, brain damage and visual dysfunction in preterm infants
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, Department of Gynecology, Hannover Medical School, OE 6415, 30623 Hannover, Germany
    Semin Fetal Neonatal Med 11:363-8. 2006
    ....
  44. doi Simulation of intra-amniotic infection and the fetal inflammatory response in a novel ex-vivo human umbilical cord perfusion model
    Sarah Hassan
    Pediatric Pulmonology and Neonatology, Hannover Medical School, Hannover, Germany
    Reprod Sci 17:426-33. 2010
    ..We aimed to design and test an ex-vivo human umbilical cord (HUC) perfusion model simulating a fetal inflammatory response (FIR) during intra-amniotic infection...
  45. pmc Risk factors and correlates of neonatal growth velocity in extremely low gestational age newborns. the ELGAN Study
    Julie Bartholomew
    Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Boston, Mass, USA
    Neonatology 104:298-304. 2013
    ..To identify maternal and infant characteristics associated with reduced growth velocity (GV) in extremely premature newborns...
  46. ncbi Multiplex measurement of cytokine/receptor gene polymorphisms and interaction between interleukin-10 (-1082) genotype and chorioamnionitis in extreme preterm delivery
    Julia Kerk
    Department of Gynecology and Obstetrics, Hannover Medical School, Hannover, Germany
    J Soc Gynecol Investig 13:350-6. 2006
    ....
  47. ncbi Risk of cranial ultrasound abnormalities in very-low-birth-weight infants conceived with assisted reproductive techniques
    Jane E Stewart
    Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
    J Perinatol 22:37-45. 2002
    ....
  48. ncbi Systemic hypotension and white-matter damage in preterm infants
    Olaf Dammann
    Children s Hospital, Boston, MA 02115, USA
    Dev Med Child Neurol 44:82-90. 2002
    ..In sum, these results do not support the hypothesis that systemic hypotension contributes to echolucency among preterm infants...
  49. pmc Cytokines and perinatal brain damage
    Olaf Dammann
    Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Boston, MA 02111, USA
    Clin Perinatol 35:643-63, v. 2008
    ..Events associated with increased circulating inflammatory cytokines, chemokines, and immune cells are described. Finally, studies of genetic variation in susceptibility to cytokine-related brain damage are reviewed...
  50. pmc ErbB receptors in fetal endothelium--a potential linkage point for inflammation-associated neonatal disorders
    Wolfgang Bueter
    Department of Pediatrics, Hannover Medical School, Carl Neuberg Str 1, 30623 Hannover, Germany
    Cytokine 36:267-75. 2006
    ..It is still unclear, whether expression patterns might be developmentally regulated and depend on the cell type studied...
  51. pmc High or low oxygen saturation and severe retinopathy of prematurity: a meta-analysis
    Minghua L Chen
    Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Box 854, 800 Washington St, Boston, MA 02111 1526, USA
    Pediatrics 125:e1483-92. 2010
    ..High oxygen saturation seems to reduce the risk at later postmenstrual ages (PMAs). However, previous clinical studies are not conclusive individually...
  52. pmc Fetal inflammatory response and brain injury in the preterm newborn
    Shadi Malaeb
    Division of Newborn Medicine, Floating Hospital for Children, Tufts Medical Center, Boston, Massachusetts 02111, USA
    J Child Neurol 24:1119-26. 2009
    ..Neuroinflammatory injury not only destroys what exists but also changes what develops...
  53. pmc Presumed and definite bacteremia in extremely low gestational age newborns
    Sonal Patel
    Floating Hospital for Children at Tufts Medical Center, Boston, MA 02111, USA
    Acta Paediatr 100:36-41. 2011
    ..To explore risk patterns for presumed and definite, early and late neonatal bacteremia...
  54. ncbi Perinatal infection, fetal inflammatory response, white matter damage, and cognitive limitations in children born preterm
    Olaf Dammann
    Neuroepidemiology Unit, Department of Neurology, Children s Hospital, Boston, Massachusetts 02115, USA
    Ment Retard Dev Disabil Res Rev 8:46-50. 2002
    ..We conclude that the relationship between antenatal infection and cognitive limitations deserves much further attention by researchers interested in the prevention of this undesirable outcome of prematurity...
  55. pmc Perinatal infection, inflammation, and retinopathy of prematurity
    Jennifer Lee
    Division of Newborn Medicine, Box 44, Floating Hospital for Children at Tufts Medical Center, 800 Washington St, Boston, MA 02111 1526, USA
    Semin Fetal Neonatal Med 17:26-9. 2012
    ..Strategies targeting inflammatory responses might help reduce the risk for ROP in extremely low gestational age newborns...
  56. ncbi Magnetic resonance and ultrasound brain imaging in preterm infants
    T MICHAEL O'SHEA
    Department of Pediatrics, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
    Early Hum Dev 81:263-71. 2005
    ..In this review we describe how well findings from these two imaging modalities agree with histology findings and neuro-developmental outcome. In addition, we discuss studies comparing ultrasound and magnetic resonance imaging findings...
  57. ncbi The adaptive immune response in neonatal cerebral white matter damage
    Alan Leviton
    Neuroepidemiology Unit, Children s Hospital Boston, 1 Autumn Street, Boston, MA 02215 5349, USA
    Ann Neurol 58:821-8. 2005
    ..These include specific recognition of bacterial antigens, specific recognition of autoantigens, polyclonal activation by Toll-like receptors, and bystander activation by cytokines...
  58. ncbi Coagulation, inflammation, and the risk of neonatal white matter damage
    Alan Leviton
    Neuroepidemiology Unit, Children s Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Pediatr Res 55:541-5. 2004
    ....
  59. ncbi Absence of pestivirus antigen in brains with white matter damage
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, Hannover Medical School, Germany
    Dev Med Child Neurol 48:290-3. 2006
    ..Further research is needed to test the hypothesis that intrauterine exposure to pestivirus antigen elicits a fetal inflammatory response which then contributes to WMD...
  60. ncbi Hospital volume and neonatal mortality among very low birth weight infants
    Dorothee B Bartels
    Department of Obstetrics, Social Medicine and Health System Research, Hannover Medical School, Hannover, Germany
    Pediatrics 117:2206-14. 2006
    ..We hypothesized that neonatal mortality would be higher in small NICUs (< 36 very low birth weight admissions per year) than in large NICUs, with adjustment for volume of the delivery unit...
  61. ncbi Impact of motor skills on cognitive test results in very-low-birthweight children
    Heike Losch
    Neuroepidemiology Unit, Department of Neurology, Children s Hospital, Harvard Medical School, Boston, MA, USA
    J Child Neurol 19:318-22. 2004
    ..Future studies need to evaluate whether factor scores only for cognitive but not motor abilities might be useful outcome variables...
  62. doi Maternal obesity and neonatal Apgar scores
    Minghua Chen
    Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    J Matern Fetal Neonatal Med 23:89-95. 2010
    ..To determine whether maternal obesity in early pregnancy is associated with low neonatal 5-min Apgar scores while adjusting for confounders...
  63. pmc White matter damage impairs adaptive recovery more than cortical damage in an in silico model of activity-dependent plasticity
    Pamela L Follett
    Floating Hospital for Children, Tufts Medical Center, and Department of Pediatrics, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    J Child Neurol 24:1205-11. 2009
    ..Better understanding of the interaction between features of preterm brain injury and developmental plasticity is an essential component for improving recovery...
  64. ncbi Anti-inflammatory and immunomodulatory strategies to protect the perinatal brain
    Adam J Wolfberg
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Tufts New England Medical Center, Boston, MA, USA
    Semin Fetal Neonatal Med 12:296-302. 2007
    ..Further research on the possible neuroprotective roles of existing medications and substances is necessary...
  65. ncbi Persistent neuro-inflammation in cerebral palsy: a therapeutic window of opportunity?
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, OE6415, Department of Obstetrics, Hannover Medical School, 30623 Hannover, Germany
    Acta Paediatr 96:6-7. 2007
  66. ncbi Maternal fever at birth and non-verbal intelligence at age 9 years in preterm infants
    Olaf Dammann
    Department of Obstetrics, Prenatal Medicine, and General Gynecology, Hannover Medical School, Germany
    Dev Med Child Neurol 45:148-51. 2003
    ..8, 0.97 to 14.6). We conclude that perinatal infection might indeed contribute to an increased risk for long-term cognitive deficits in preterm infants...
  67. ncbi The wealth of information conveyed by gestational age
    Alan Leviton
    Children s Hospital and Department of Neurology, Harvard Medical School, Boston, MA 02115, USA
    J Pediatr 146:123-7. 2005
  68. ncbi Evidence-based child neurology
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, Department of Obstetrics, Hannover Medical School, Hannover, Germany
    Dev Med Child Neurol 48:622-4. 2006
    ..Therefore, evidence-based child neurology might benefit not only from the therapeutic, but also from the diagnostic and etiological components of epidemiology...
  69. ncbi Paediatric neurology: the many faces of development
    Olaf Dammann
    Hannover Medical School, Hannover, Germany
    Lancet Neurol 6:12-4. 2007
  70. ncbi Protein detection in dried blood by surface-enhanced laser desorption/ionization-time of flight mass spectrometry (SELDI-TOF MS)
    Christiane E L Dammann
    Department of Pediatric Pulmonology and Neonatology, Hannover Medical School, Hannover, Germany
    Biol Neonate 89:126-32. 2006
    ..The rapid and reliable identification of biomarkers in the smallest possible amount of blood remains a challenge in biomarker epidemiological research involving preterm newborns...
  71. ncbi Association of two mutations in the CHEK2 gene with breast cancer
    Natalia Bogdanova
    Gynecology Research Unit, Hannover Medical School, Hannover, Germany
    Int J Cancer 116:263-6. 2005
    ..Family history of breast cancer did not differ between carriers and noncarriers. Our data indicate that the I157T allele, and possibly the IVS2+1G > A allele, of the CHEK2 gene contribute to inherited breast cancer susceptibility...
  72. doi Policy benchmarking report on neonatal health and social policies in 13 European countries
    Matthias Keller
    Department of Pediatrics, Neonatology, University Hospital Essen, Germany
    Acta Paediatr 99:1624-9. 2010
    ..In Europe, the prevalence rate of premature birth ranges from 5.5 to 11.4% - an average of 7.1% of all live births. In this report, we aim to compare the current health and social policies, as well as practices in 13 EU member states...
  73. pmc An algorithm for identifying and classifying cerebral palsy in young children
    Karl C K Kuban
    Division of Pediatric Neurology, Department of Pediatrics, Boston Medical Center, Boston University, Boston, MA, USA
    J Pediatr 153:466-72. 2008
    ....
  74. ncbi Antimicrobial resistance in Escherichia coli sepsis
    Olaf Dammann
    Pediatr Infect Dis J 23:978-9; author reply 979-80. 2004
  75. ncbi Preconditioning and the developing brain
    Henrik Hagberg
    Department of Obstetrics and Gynecology, Institute of Women s and Children s Health, Goteborg University, Goteborg, Sweden
    Semin Perinatol 28:389-95. 2004
    ..Preconditioning of the brain or induction of tolerance of the immune system might be utilized in the future to decrease CNS vulnerability and the occurrence of perinatal brain injury...
  76. ncbi Biomarker epidemiology of cerebral palsy
    Olaf Dammann
    Ann Neurol 55:158-61. 2004
  77. ncbi Neuroimaging and the prediction of outcomes in preterm infants
    Olaf Dammann
    N Engl J Med 355:727-9. 2006
  78. ncbi Neurological sequelae in in-vitro fertilisation babies
    Alan Leviton
    Lancet 360:718; author reply 719. 2002
  79. ncbi Periventricular leukomalacia might not specifically affect cortical magnetoencephalographic response to biological motion
    Olaf Dammann
    Ann Neurol 60:269; author reply 269-70. 2006
  80. ncbi NEOBRAIN--an EU-funded project committed to protect the newborn brain
    Olaf Dammann
    Neonatology 92:217-8. 2007