Ethan M Balk

Summary

Affiliation: Tufts-New England Medical Center
Country: USA

Publications

  1. ncbi request reprint Effectiveness of management strategies for renal artery stenosis: a systematic review
    Ethan Balk
    Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Ann Intern Med 145:901-12. 2006
  2. ncbi request reprint A collaborative effort to apply the evidence-based review process to the field of nutrition: challenges, benefits, and lessons learned
    Ethan M Balk
    Tufts New England Medical Center Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Clin Nutr 85:1448-56. 2007
  3. ncbi request reprint Effect of chromium supplementation on glucose metabolism and lipids: a systematic review of randomized controlled trials
    Ethan M Balk
    Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, 750 Washington St, NEMC 63, Boston, MA 02111, USA
    Diabetes Care 30:2154-63. 2007
  4. ncbi request reprint Vitamin B6, B12, and folic acid supplementation and cognitive function: a systematic review of randomized trials
    Ethan M Balk
    Tufts New England Medical Center Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Boston, MA 02111, USA
    Arch Intern Med 167:21-30. 2007
  5. ncbi request reprint Effects of omega-3 fatty acids on serum markers of cardiovascular disease risk: a systematic review
    Ethan M Balk
    Tufts New England Medical Center Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, NEMC 63, Boston, MA 02111, USA
    Atherosclerosis 189:19-30. 2006
  6. ncbi request reprint Cholestanol: a serum marker to guide LDL cholesterol-lowering therapy
    Michel R Hoenig
    Royal Brisbane and Women s Hospital, Level 5 Pigeon Holes, Herton Road, Herston, Brisbane, QLD 4029, Australia
    Atherosclerosis 184:247-54. 2006
  7. ncbi request reprint Reading and critically appraising systematic reviews and meta-analyses: a short primer with a focus on hepatology
    Ethan M Balk
    Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, 750 Washington Street, NEMC 63, Boston, MA 02111, USA
    J Hepatol 43:729-36. 2005
  8. ncbi request reprint Effects of omega-3 fatty acids on coronary restenosis, intima-media thickness, and exercise tolerance: a systematic review
    Ethan M Balk
    Tufts New England Medical Center Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, 750 Washington Street, NEMC 63, Boston, MA 02111, USA
    Atherosclerosis 184:237-46. 2006
  9. pmc Systematic review to support the development of nutrient reference intake values: challenges and solutions
    Mei Chung
    Tufts Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA02111, USA
    Am J Clin Nutr 92:273-6. 2010
  10. ncbi request reprint n-3 Fatty acids from fish or fish-oil supplements, but not alpha-linolenic acid, benefit cardiovascular disease outcomes in primary- and secondary-prevention studies: a systematic review
    Chenchen Wang
    Tufts New England Medical Center Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, Boston, MA, USA
    Am J Clin Nutr 84:5-17. 2006

Detail Information

Publications49

  1. ncbi request reprint Effectiveness of management strategies for renal artery stenosis: a systematic review
    Ethan Balk
    Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Ann Intern Med 145:901-12. 2006
    ..Atherosclerotic renal artery stenosis is increasingly common in an aging population. Therapeutic options include medical treatment only or revascularization procedures...
  2. ncbi request reprint A collaborative effort to apply the evidence-based review process to the field of nutrition: challenges, benefits, and lessons learned
    Ethan M Balk
    Tufts New England Medical Center Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Clin Nutr 85:1448-56. 2007
    ..The goals of these systematic reviews, the processes that were used, the benefits and limitations of the collaboration, and the conclusions of the reviews, including recommendations for future research, are summarized here...
  3. ncbi request reprint Effect of chromium supplementation on glucose metabolism and lipids: a systematic review of randomized controlled trials
    Ethan M Balk
    Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, 750 Washington St, NEMC 63, Boston, MA 02111, USA
    Diabetes Care 30:2154-63. 2007
    ..A systematic review of the effect of chromium supplementation on glucose metabolism and lipid levels...
  4. ncbi request reprint Vitamin B6, B12, and folic acid supplementation and cognitive function: a systematic review of randomized trials
    Ethan M Balk
    Tufts New England Medical Center Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Boston, MA 02111, USA
    Arch Intern Med 167:21-30. 2007
    ..A systematic review of the effect of pyridoxine hydrochloride (hereinafter "vitamin B(6)"), cyanocobalamin or hydroxycobalamin (hereinafter "vitamin B(12)"), and folic acid supplementation on cognitive function was performed...
  5. ncbi request reprint Effects of omega-3 fatty acids on serum markers of cardiovascular disease risk: a systematic review
    Ethan M Balk
    Tufts New England Medical Center Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, NEMC 63, Boston, MA 02111, USA
    Atherosclerosis 189:19-30. 2006
    ..The evidence regarding the effects of omega-3 fatty acids on hs-CRP is inconclusive, as are data on ALA...
  6. ncbi request reprint Cholestanol: a serum marker to guide LDL cholesterol-lowering therapy
    Michel R Hoenig
    Royal Brisbane and Women s Hospital, Level 5 Pigeon Holes, Herton Road, Herston, Brisbane, QLD 4029, Australia
    Atherosclerosis 184:247-54. 2006
    ..By determining whether a patient is mainly a synthesizer or absorber of cholesterol, customized regimens can be used and are expected to improve patient outcomes and minimize costs of treatment...
  7. ncbi request reprint Reading and critically appraising systematic reviews and meta-analyses: a short primer with a focus on hepatology
    Ethan M Balk
    Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, 750 Washington Street, NEMC 63, Boston, MA 02111, USA
    J Hepatol 43:729-36. 2005
  8. ncbi request reprint Effects of omega-3 fatty acids on coronary restenosis, intima-media thickness, and exercise tolerance: a systematic review
    Ethan M Balk
    Tufts New England Medical Center Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, 750 Washington Street, NEMC 63, Boston, MA 02111, USA
    Atherosclerosis 184:237-46. 2006
    ..The dearth of long term data on fish consumption or omega-3 fatty acid supplementation on measures of cardiovascular disease risk severely limits our ability to draw definitive conclusions at this time...
  9. pmc Systematic review to support the development of nutrient reference intake values: challenges and solutions
    Mei Chung
    Tufts Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA02111, USA
    Am J Clin Nutr 92:273-6. 2010
    ..The experiences described in this article can serve as a basis for future improvements in systematic reviews of nutrients and to better integrate systematic review into development of future nutrient reference values...
  10. ncbi request reprint n-3 Fatty acids from fish or fish-oil supplements, but not alpha-linolenic acid, benefit cardiovascular disease outcomes in primary- and secondary-prevention studies: a systematic review
    Chenchen Wang
    Tufts New England Medical Center Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, Boston, MA, USA
    Am J Clin Nutr 84:5-17. 2006
    ..The evidence for the benefits of fish oil is stronger in secondary- than in primary-prevention settings. Adverse effects appear to be minor...
  11. ncbi request reprint Heterogeneity and lack of good quality studies limit association between folate, vitamins B-6 and B-12, and cognitive function
    Gowri Raman
    Tufts New England Medical Center Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, Boston, MA 02111, USA
    J Nutr 137:1789-94. 2007
    ....
  12. pmc Reporting of systematic reviews of micronutrients and health: a critical appraisal
    Mei Chung
    Tufts Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA 02111, USA
    Am J Clin Nutr 89:1099-113. 2009
    ..The quality of nutrition-related systematic reviews (SRs) is an unstudied but important factor affecting their usefulness...
  13. doi request reprint Self-measured blood pressure monitoring in the management of hypertension: a systematic review and meta-analysis
    Katrin Uhlig
    Center for Clinical Evidence Synthesis, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, Massachusetts 02111, USA
    Ann Intern Med 159:185-94. 2013
    ..Clinical guidelines recommend that adults with hypertension self-monitor their blood pressure (BP)...
  14. doi request reprint Predictors of atrial fibrillation recurrence after radiofrequency catheter ablation: a systematic review
    Ethan M Balk
    Tufts Evidence based Practice Center, TuftsMedical Center, Boston, Massachusetts, USA
    J Cardiovasc Electrophysiol 21:1208-16. 2010
    ..AF Recurrence After RFA: Systematic Review...
  15. pmc Efficacy and safety of combined vs. single renin-angiotensin-aldosterone system blockade in chronic kidney disease: a meta-analysis
    Paweena Susantitaphong
    Department of Medicine, Division of Nephrology, Kidney and Dialysis Research Laboratory, St Elizabeth s Medical Center, Boston, MA, USA
    Am J Hypertens 26:424-41. 2013
    ..We conducted a meta-analysis of all randomized controlled trials comparing the efficacy and safety of combined vs. single RAAS blockade therapy in chronic kidney disease (CKD)...
  16. pmc Dose of erythropoiesis-stimulating agents and adverse outcomes in CKD: a metaregression analysis
    Ioannis Koulouridis
    Department of Medicine, Division of Nephrology, Kidney and Dialysis Research Laboratory, St Elizabeth s Medical Center, Boston, MA 02135, USA
    Am J Kidney Dis 61:44-56. 2013
    ..Targeting higher hemoglobin levels with erythropoiesis-stimulating agents (ESAs) to treat the anemia of chronic kidney disease (CKD) is associated with increased cardiovascular risk...
  17. pmc GFR at initiation of dialysis and mortality in CKD: a meta-analysis
    Paweena Susantitaphong
    Department of Medicine, Division of Nephrology, Kidney and Dialysis Research Laboratory, St Elizabeth s Medical Center, Boston, MA 02135, USA
    Am J Kidney Dis 59:829-40. 2012
    ..Recent data suggest that higher GFR may be associated with increased mortality...
  18. pmc Systematic review: Vitamin D and cardiometabolic outcomes
    Anastassios G Pittas
    Tufts Medical Center and Friedman School of Nutrition Science and Policy, and Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    Ann Intern Med 152:307-14. 2010
    ..Vitamin D may modify risk for cardiometabolic outcomes (type 2 diabetes, hypertension, or cardiovascular disease)...
  19. pmc Short- and long-term effects of alkali therapy in chronic kidney disease: a systematic review
    Paweena Susantitaphong
    Division of Nephrology, Kidney and Dialysis Research Laboratory, Department of Medicine, St Elizabeth s Medical Center, Boston, MA 02135, USA
    Am J Nephrol 35:540-7. 2012
    ..We systematically reviewed the effect of sodium bicarbonate on benefits and harms in patients with CKD...
  20. doi request reprint Active surveillance in men with localized prostate cancer: a systematic review
    Issa J Dahabreh
    Tufts Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Boston, Massachusetts, USA
    Ann Intern Med 156:582-90. 2012
    ..Active surveillance (AS) and watchful waiting (WW) have been proposed as management strategies for low-risk, localized prostate cancer...
  21. pmc Effect of frequent or extended hemodialysis on cardiovascular parameters: a meta-analysis
    Paweena Susantitaphong
    Department of Medicine, Division of Nephrology, Kidney and Dialysis Research Laboratory, St Elizabeth s Medical Center, Boston, MA 02135, USA
    Am J Kidney Dis 59:689-99. 2012
    ..Increased left ventricular (LV) mass is a risk factor for cardiovascular mortality in patients with chronic kidney failure. More frequent or extended hemodialysis (HD) has been hypothesized to have a beneficial effect on LV mass...
  22. ncbi request reprint Comparability of methods for LDL subfraction determination: A systematic review
    Mei Chung
    Tufts Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Boston, MA 02111, United States
    Atherosclerosis 205:342-8. 2009
    ....
  23. ncbi request reprint Systematic review: association of low-density lipoprotein subfractions with cardiovascular outcomes
    Stanley Ip
    Tufts Medical Center and Tufts University, Boston, Massachusetts 02111, USA
    Ann Intern Med 150:474-84. 2009
    ..Measures of low-density lipoprotein (LDL) subfractions have been proposed as an independent risk factor for cardiovascular disease...
  24. doi request reprint The vulnerable atherosclerotic plaque: scope of the literature
    Alawi A Alsheikh-Ali
    Institute for Clinical Research and Health Policy Studies, Tufts University School of Medicine, Boston, MA, USA
    Ann Intern Med 153:387-95. 2010
    ..Large prospective studies in patients with and without previous cardiovascular events during long follow-up are required to validate this concept...
  25. pmc High priority future research needs for obstructive sleep apnea diagnosis and treatment
    Kamal Patel
    Institute of Clinical Research and Health Policy Studies, Tufts University School of Medicine, Tufts Medical Center, Boston, MA, USA
    J Clin Sleep Med 9:395-402. 2013
    ..To identify and prioritize future research needs (FRN) topics for diagnosis and treatment of obstructive sleep apnea (OSA)...
  26. pmc Auto-titrating versus fixed continuous positive airway pressure for the treatment of obstructive sleep apnea: a systematic review with meta-analyses
    Stanley Ip
    Institute of Clinical Research and Health Policy Studies, Tufts University School of Medicine, Tufts Medical Center, Boston, MA, USA
    Syst Rev 1:20. 2012
    ..Obstructive sleep apnea is a relatively common disorder that can lead to lost productivity and cardiovascular disease. The form of positive airway treatment that should be offered is unclear...
  27. doi request reprint Two methods provide similar signals for the need to update systematic reviews
    Mei Chung
    Tufts Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA 02111, USA
    J Clin Epidemiol 65:660-8. 2012
    ..Apply and compare two methods that identify signals for the need to update systematic reviews, using three Evidence-based Practice Center reports on omega-3 fatty acids as test cases...
  28. pmc Opportunities and challenges in conducting systematic reviews to support the development of nutrient reference values: vitamin A as an example
    Robert Russell
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
    Am J Clin Nutr 89:728-33. 2009
    ..Ultimately, an objective, unbiased systematic review of a defined question could be useful, not only in helping to set nutrient reference values, but also for increasing the transparency of the decision making process...
  29. pmc Off-pump coronary artery bypass surgery and acute kidney injury: a meta-analysis of randomized controlled trials
    Victor F Seabra
    Department of Medicine, Division of Nephrology, Kidney and Dialysis Research Laboratory, St Elizabeth s Medical Center, Boston, Massachusetts 02135, USA
    Clin J Am Soc Nephrol 5:1734-44. 2010
    ..This meta-analysis compares these two surgical techniques with respect to causing acute kidney injury (AKI)...
  30. ncbi request reprint Effects of statins on nonlipid serum markers associated with cardiovascular disease: a systematic review
    Ethan M Balk
    Tufts University School of Medicine and Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Ann Intern Med 139:670-82. 2003
    ..Statins reduce cardiovascular events to a greater extent than can be explained by their effect on lipids. Several studies have attempted to elucidate mechanisms by which statins reduce cardiovascular risk...
  31. pmc Short-term efficacy and safety of vasopressin receptor antagonists for treatment of hyponatremia
    Bertrand L Jaber
    Department of Medicine, Division of Nephrology, Kidney and Dialysis Research Laboratory, St Elizabeth s Medical Center, Boston, MA 02135, USA
    Am J Med 124:977.e1-9. 2011
    ..We performed a meta-analysis to systematically measure efficacy and safety of vasopressin receptor antagonists (VRAs) tested in randomized controlled trials for treatment of hyponatremia...
  32. ncbi request reprint Insulin therapy and acute kidney injury in critically ill patients a systematic review
    George Thomas
    Caritas St Elizabeth s Medical Center, 736 Cambridge Street, Boston, MA 02135, USA
    Nephrol Dial Transplant 22:2849-55. 2007
    ..We performed a systematic review and meta-analysis to ascertain the effect of intensive insulin therapy on the incidence of acute kidney injury (AKI) in adult critically ill patients...
  33. ncbi request reprint Adverse events following implantable cardioverter defibrillator implantation: a systematic review
    Rebecca Persson
    Center for Clinical Evidence Research, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, USA
    J Interv Card Electrophysiol 40:191-205. 2014
    ..We summarized the evidence on adverse events from ICDs with a focus on ICD use for primary prevention of sudden cardiac death...
  34. pmc A Web-based archive of systematic review data
    Stanley Ip
    Tufts Evidence based Practice Center, Tufts Medical Center, Boston, MA 02111, USA
    Syst Rev 1:15. 2012
    ..Herein we provide an account of the rationale and development of the Systematic Review Data Repository thus far, as well as outline its future trajectory...
  35. doi request reprint Cinacalcet for the treatment of hyperparathyroidism in kidney transplant recipients: a systematic review and meta-analysis
    Jordana B Cohen
    Department of Medicine, Boston University Medical Center, Boston, MA, USA
    Transplantation 94:1041-8. 2012
    ..Multiple observational studies have investigated treatment of posttransplant hyperparathyroidism with the calcimimetic agent cinacalcet...
  36. doi request reprint Lipid-lowering therapy in persons with chronic kidney disease: a systematic review and meta-analysis
    Ashish Upadhyay
    Renal Section, Department of Medicine, Boston Medical Center and Boston University School of Medicine, 72 East Concord Street, Evans 124, Boston, MA 02118, USA
    Ann Intern Med 157:251-62. 2012
    ..Lipid-lowering therapy is not widely used in persons with chronic kidney disease (CKD) despite a high burden of dyslipidemia and cardiovascular disease in this population...
  37. ncbi request reprint Systematic review: comparative effectiveness of radiofrequency catheter ablation for atrial fibrillation
    Teruhiko Terasawa
    Tufts Medical Center, Boston, Massachusetts 02111, USA
    Ann Intern Med 151:191-202. 2009
    ..Atrial fibrillation is the most common sustained arrhythmia. Medical treatment often fails to control symptoms...
  38. ncbi request reprint Gender differences in plasma lipid response to dietary fat
    Annie Lapointe
    Cardiovascular Nutrition Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts, USA
    Nutr Rev 64:234-49. 2006
    ....
  39. ncbi request reprint A systematic review of the effect of the Excebrane dialyser on biomarkers of lipid peroxidation
    Marie Anne Sosa
    Department of Medicine, Tufts University School of Medicine, Boston, MA 02135, USA
    Nephrol Dial Transplant 21:2825-33. 2006
    ..We conducted a systematic review and meta-analysis to examine the effect of Excebrane, a vitamin E-coated cellulose-based dialyser, on circulating biomarkers of lipid peroxidation, as surrogate markers of oxidative stress...
  40. doi request reprint KDOQI US commentary on the KDIGO clinical practice guideline for the prevention, diagnosis, evaluation, and treatment of hepatitis C in CKD
    Craig E Gordon
    Tufts Center for Guideline Development and Implementation, Tufts Medical Center, Boston, MA, USA
    Am J Kidney Dis 52:811-25. 2008
    ..Research recommendations that are of particular interest to the United States are then summarized to highlight future areas of inquiry that would enable updating of the guidelines...
  41. doi request reprint Data extraction from machine-translated versus original language randomized trial reports: a comparative study
    Ethan M Balk
    Tufts Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, 800 Washington Street, Box 63, Boston, MA 02111, USA
    Syst Rev 2:97. 2013
    ..Google Translate offers free Web-based translation, but it is unknown whether its translation accuracy is sufficient to use in systematic reviews to mitigate concerns about language bias...
  42. doi request reprint Molecular adsorbent recirculating system as artificial support therapy for liver failure: a meta-analysis
    Arjun Vaid
    Department of Medicine, St Elizabeth s Medical Center, Boston, Massachusetts 02135, USA
    ASAIO J 58:51-9. 2012
    ..Large studies are required to assess the merit of this promising therapy on patient-centered outcomes...
  43. ncbi request reprint Meta-analysis: the effect of dietary counseling for weight loss
    Michael L Dansinger
    Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Ann Intern Med 147:41-50. 2007
    ..Dietary and lifestyle modification efforts are the primary treatments for people who are obese or overweight. The effect of dietary counseling on long-term weight change is unclear...
  44. doi request reprint Pneumothorax following thoracentesis: a systematic review and meta-analysis
    Craig E Gordon
    Renal Section, Department of Medicine, Boston University Medical Center, Boston, MA 02118, USA
    Arch Intern Med 170:332-9. 2010
    ..We aimed to determine the mean pneumothorax rate following thoracentesis and to identify risk factors for pneumothorax through a systematic review and meta-analysis...
  45. ncbi request reprint Correlation of quality measures with estimates of treatment effect in meta-analyses of randomized controlled trials
    Ethan M Balk
    Evidence Based Practice Center, Division of Clinical Care Research, Tufts University School of Medicine, New England Medical Center, 750 Washington St, No 63, Boston, MA 02111, USA
    JAMA 287:2973-82. 2002
    ..Therefore, assessment of trial quality is often used in meta-analysis. However, the degree to which specific quality measures are associated with treatment effects has not been well established across a broad range of clinical areas...
  46. pmc Therapeutic hypothermia and prevention of acute kidney injury: a meta-analysis of randomized controlled trials
    Paweena Susantitaphong
    Division of Nephrology, Department of Medicine, St Elizabeth s Medical Center, Tufts University School of Medicine, 736 Cambridge Street, Boston, MA 02135, USA
    Resuscitation 83:159-67. 2012
    ..We conducted a systematic review to ascertain the effect of therapeutic hypothermia on development of acute kidney injury (AKI) and mortality...
  47. ncbi request reprint Short stature and functional impairment: a systematic review
    Patricia G Wheeler
    Division of Genetics, Department of Pediatrics, Tufts University School of Medicine, Floating Hospital for Children, Boston, MA, USA
    Arch Pediatr Adolesc Med 158:236-43. 2004
    ..To review the available evidence on the association between primary short stature and intellectual and physical dysfunction among children...
  48. ncbi request reprint Effects of statins on vascular structure and function: a systematic review
    Ethan M Balk
    Center for Clinical Evidence Synthesis, Institute for Clinical Research and Health Policy Studies
    Am J Med 117:775-90. 2004
    ..We conducted a systematic review of how statins affect vascular structure and function, differences among statins, and correlations between the effects of statins on vascular outcomes and either lipid levels or cardiovascular outcomes...
  49. ncbi request reprint Clinical practice guidelines in nephrology--for worse or for better
    Katrin Uhlig
    Nephrol Dial Transplant 21:1145-53. 2006