Research Topics
| Min Fu TsanSummaryCountry: USA Publications
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Detail Information
Publications
Heat shock proteins and high mobility group box 1 protein lack cytokine functionMin Fu Tsan
Research Service, Veterans Affairs Medical Center, Washington, DC, USA
J Leukoc Biol 89:847-53. 2011..The significance of these cytokine-enhancing effects of HSPs and HMGB1 needs further investigation...
Heat shock proteins and immune systemMin Fu Tsan
Office of Research Oversight, Department of Veterans Affairs, 50 Irving Street, N W, Washington, DC 20422, USA
J Leukoc Biol 85:905-10. 2009..The reported antigen presentation and cross-presentation and in vitro HSP cytokine functions are a result of molecules bound to or chaperoned by HSPs but not a result of HSPs themselves...
Endotoxin contamination in recombinant human heat shock protein 70 (Hsp70) preparation is responsible for the induction of tumor necrosis factor alpha release by murine macrophagesBaochong Gao
Institute for Clinical Research and Veterans Affairs Medical Center, Washington, DC 20422, USA
J Biol Chem 278:174-9. 2003..These results suggest that rhHsp-70 does not induce TNFalpha release from murine macrophages and that the observed TNFalpha-inducing activity in the rhHsp70-2 preparation is entirely due to the contaminating LPS...
Endogenous ligands of Toll-like receptorsMin Fu Tsan
Office of Research Oversight, Department of Veterans Affairs, 50 Irving Street, NW, Washington, DC 20422, USA
J Leukoc Biol 76:514-9. 2004....
Recombinant human heat shock protein 60 does not induce the release of tumor necrosis factor alpha from murine macrophagesBaochong Gao
Institute for Clinical Research, Washington, D C 20422, USA
J Biol Chem 278:22523-9. 2003..Approximately 50% of the observed TNF-alpha-inducing activity in the rhHSP60-2 preparation is due to LPS contamination, whereas the rest of the activity was due to the contamination of LPS-associated molecule(s)...
Induction of cytokines by heat shock proteins and endotoxin in murine macrophagesBaochong Gao
Institute for Clinical Research, Washington, DC 20422, USA
Biochem Biophys Res Commun 317:1149-54. 2004..These data suggest that rhHsp60 and rhHsp70 do not activate cytokine genes in murine macrophages...
Heat shock protein and innate immunityMin Fu Tsan
Research Service, VA Medical Center, Washington DC 20422, USA
Cell Mol Immunol 1:274-9. 2004..This concise review summarizes the current controversy over the role of HSPs in innate immunity...
Cytokine function of heat shock proteinsMin Fu Tsan
Research Service, Veterans Affairs Medical Center, Washington, DC 20422, USA
Am J Physiol Cell Physiol 286:C739-44. 2004....
The heat sensitivity of cytokine-inducing effect of lipopolysaccharideBaochong Gao
Research Service, VA Medical Center, Washington, DC, USA
J Leukoc Biol 80:359-66. 2006....
Effect of resveratrol on growth of 4T1 breast cancer cells in vitro and in vivoKathleen Bove
Research Service, Stratton VA Medical Center, Albany, New York 12208, USA
Biochem Biophys Res Commun 291:1001-5. 2002..Resveratrol, therefore, is a potent inhibitor of 4T1 breast cancer cells in vitro; is nontoxic to mice at 1-5 mg/kg; and has no growth-inhibitory effect on 4T1 breast cancer in vivo...
Role of alpha(v)beta(3)-integrin in TNF-alpha-induced endothelial cell migrationBaochong Gao
Department of Physiology, Albany Medical College, Albany, NY 12208, USA
Am J Physiol Cell Physiol 283:C1196-205. 2002....
Toll-like receptors, inflammation and cancerMin Fu Tsan
Research Service, Veterans Affairs Medical Center, 50 Irving Street, NW, Washington, DC 20422, USA
Semin Cancer Biol 16:32-7. 2006..Further studies are necessary to define the existence of endogenous TLR ligands and their potential contribution to the immunosuppression in cancer...
Pathogen-associated molecular pattern contamination as putative endogenous ligands of Toll-like receptorsMin Fu Tsan
Department of Veterans Affairs, Research Service, VA Medical Center, Washington, DC 20422, USA
J Endotoxin Res 13:6-14. 2007..Strategies are proposed to avoid future designation of PAMP contamination as putative endogenous ligands of TLRs...
Anti-leukemia effect of resveratrolMin Fu Tsan
Office of Research Compliance and Assurance, Department of Veterans Affairs, Washington, DC 20422, USA
Leuk Lymphoma 43:983-7. 2002..Because of its low in vivo toxicity, resveratrol deserves further investigation as an anti-leukemia agent...
