Lance B Price

Summary

Affiliation: Translational Genomics Research Institute
Country: USA

Publications

  1. pmc In vitro selection and characterization of Bacillus anthracis mutants with high-level resistance to ciprofloxacin
    Lance B Price
    Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona 86011 5640, USA
    Antimicrob Agents Chemother 47:2362-5. 2003
  2. pmc Male circumcision significantly reduces prevalence and load of genital anaerobic bacteria
    Cindy M Liu
    Division of Pathogen Genomics, Translational Genomics Research Institute, Flagstaff, Arizona, USA
    MBio 4:e00076. 2013
  3. pmc Multidrug-Resistant Staphylococcus aureus in US Meat and Poultry
    Andrew E Waters
    Division of Pathogen Genomics, Translational Genomics Research Institute, Northern Arizona University, Flagstaff, USA
    Clin Infect Dis 52:1227-30. 2011
  4. pmc Community analysis of chronic wound bacteria using 16S rRNA gene-based pyrosequencing: impact of diabetes and antibiotics on chronic wound microbiota
    Lance B Price
    Translational Genomics Research Institute, Flagstaff, Arizona, United States of America
    PLoS ONE 4:e6462. 2009
  5. pmc The effects of circumcision on the penis microbiome
    Lance B Price
    Translational Genomics Research Institute TGen, Flagstaff, Arizona, United States of America
    PLoS ONE 5:e8422. 2010
  6. pmc Macroscale spatial variation in chronic wound microbiota: a cross-sectional study
    Lance B Price
    Center for Microbiomics and Human Health, Translational Genomics Research Institute, Flagstaff, Arizona 86001, USA
    Wound Repair Regen 19:80-8. 2011
  7. pmc The epidemic of extended-spectrum-β-lactamase-producing Escherichia coli ST131 is driven by a single highly pathogenic subclone, H30-Rx
    Lance B Price
    Division of Pathogen Genomics, The Translational Genomics Research Institute, Flagstaff, Arizona, USA
    MBio 4:e00377-13. 2013
  8. pmc Medical therapy reduces microbiota diversity and evenness in surgically recalcitrant chronic rhinosinusitis
    Cindy M Liu
    Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, AZ Center for Microbiomics and Human Health, Translational Genomics Research Institute, Flagstaff, AZ Department of Pathology, The Johns Hopkins School of Medicine, Baltimore, MD
    Int Forum Allergy Rhinol 3:775-81. 2013
  9. pmc Genotyping of Brucella species using clade specific SNPs
    Jeffrey T Foster
    Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, AZ 86011 4073, USA
    BMC Microbiol 12:110. 2012
  10. ncbi request reprint The Semen Microbiome and Its Relationship with Local Immunology and Viral Load in HIV Infection
    Cindy M Liu
    Department of Pathology, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, Arizona, United States of America Center for Microbiomics and Human Health, Translational Genomics Research Institute, Flagstaff, Arizona, United States of America
    PLoS Pathog 10:e1004262. 2014

Collaborators

Detail Information

Publications19

  1. pmc In vitro selection and characterization of Bacillus anthracis mutants with high-level resistance to ciprofloxacin
    Lance B Price
    Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona 86011 5640, USA
    Antimicrob Agents Chemother 47:2362-5. 2003
    ..Mutants for which MICs were 32 microg/ml had no additional target modifications but showed evidence of enhanced ciprofloxacin efflux...
  2. pmc Male circumcision significantly reduces prevalence and load of genital anaerobic bacteria
    Cindy M Liu
    Division of Pathogen Genomics, Translational Genomics Research Institute, Flagstaff, Arizona, USA
    MBio 4:e00076. 2013
    ..While aerobic bacterial taxa also increased postcircumcision, these gains were minor. The reduction in anaerobes may partly account for the effects of circumcision on reduced HIV acquisition...
  3. pmc Multidrug-Resistant Staphylococcus aureus in US Meat and Poultry
    Andrew E Waters
    Division of Pathogen Genomics, Translational Genomics Research Institute, Northern Arizona University, Flagstaff, USA
    Clin Infect Dis 52:1227-30. 2011
    ..S. aureus contaminated 47% of samples, and multidrug resistance was common among isolates (52%). S. aureus genotypes and resistance profiles differed significantly among sample types, suggesting food animal-specific contamination...
  4. pmc Community analysis of chronic wound bacteria using 16S rRNA gene-based pyrosequencing: impact of diabetes and antibiotics on chronic wound microbiota
    Lance B Price
    Translational Genomics Research Institute, Flagstaff, Arizona, United States of America
    PLoS ONE 4:e6462. 2009
    ..We characterized wound bacteria from a cohort of chronic wound patients using a 16S rRNA gene-based pyrosequencing approach and assessed the impact of diabetes and antibiotics on chronic wound microbiota...
  5. pmc The effects of circumcision on the penis microbiome
    Lance B Price
    Translational Genomics Research Institute TGen, Flagstaff, Arizona, United States of America
    PLoS ONE 5:e8422. 2010
    ..Circumcision is associated with significant reductions in HIV, HSV-2 and HPV infections among men and significant reductions in bacterial vaginosis among their female partners...
  6. pmc Macroscale spatial variation in chronic wound microbiota: a cross-sectional study
    Lance B Price
    Center for Microbiomics and Human Health, Translational Genomics Research Institute, Flagstaff, Arizona 86001, USA
    Wound Repair Regen 19:80-8. 2011
    ..A composite sample from multiple sites across the surface of individual wounds may provide the most robust characterization of wound microbiota...
  7. pmc The epidemic of extended-spectrum-β-lactamase-producing Escherichia coli ST131 is driven by a single highly pathogenic subclone, H30-Rx
    Lance B Price
    Division of Pathogen Genomics, The Translational Genomics Research Institute, Flagstaff, Arizona, USA
    MBio 4:e00377-13. 2013
    ..5; P < 0.001). Together, these results suggest that the high prevalence of CTX-M-15 production among ST131 isolates is due primarily to the expansion of a single, highly virulent subclone, H30-Rx...
  8. pmc Medical therapy reduces microbiota diversity and evenness in surgically recalcitrant chronic rhinosinusitis
    Cindy M Liu
    Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, AZ Center for Microbiomics and Human Health, Translational Genomics Research Institute, Flagstaff, AZ Department of Pathology, The Johns Hopkins School of Medicine, Baltimore, MD
    Int Forum Allergy Rhinol 3:775-81. 2013
    ..Chronic rhinosinusitis (CRS) is a highly prevalent and heterogeneous condition frequently treated with antibiotics and corticosteroid therapy. However, the effect of medical therapy on sinus microbiota remains unknown...
  9. pmc Genotyping of Brucella species using clade specific SNPs
    Jeffrey T Foster
    Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, AZ 86011 4073, USA
    BMC Microbiol 12:110. 2012
    ....
  10. ncbi request reprint The Semen Microbiome and Its Relationship with Local Immunology and Viral Load in HIV Infection
    Cindy M Liu
    Department of Pathology, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, Arizona, United States of America Center for Microbiomics and Human Health, Translational Genomics Research Institute, Flagstaff, Arizona, United States of America
    PLoS Pathog 10:e1004262. 2014
    ..15, p = 0.02). HIV infection reshapes the relationship between semen bacteria and pro-inflammatory cytokines, and both are linked to semen VL, which supports a role of the semen microbiome in HIV sexual transmission. ..
  11. pmc FungiQuant: a broad-coverage fungal quantitative real-time PCR assay
    Cindy M Liu
    Division of Pathogen Genomics, Translational Genomics Research Institute, Flagstaff, AZ 86011, USA
    BMC Microbiol 12:255. 2012
    ..Fungal load quantification is a critical component of fungal community analyses. Limitation of current approaches for quantifying the fungal component in the human microbiome suggests the need for new broad-coverage techniques...
  12. pmc Rapid differentiation between livestock-associated and livestock-independent Staphylococcus aureus CC398 clades
    Marc Stegger
    Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark Translational Genomics Research Institute, Pathogen Genomics Division, Flagstaff, Arizona, United States of America
    PLoS ONE 8:e79645. 2013
    ..aureus CC398 isolates. The simple assays described here generate signals comparable to a whole-genome phylogeny for major clade assignment and are easily integrated into S. aureus CC398 surveillance programs and epidemiological studies. ..
  13. pmc BactQuant: an enhanced broad-coverage bacterial quantitative real-time PCR assay
    Cindy M Liu
    Division of Pathogen Genomics, Translational Genomics Research Institute, 3051 W, Shamrell Blvd, Suite 106, Flagstaff, AZ 86001, USA
    BMC Microbiol 12:56. 2012
    ..We further utilized in silico evaluation to complement laboratory-based qPCR characterization to validate BactQuant...
  14. doi request reprint The otologic microbiome: a study of the bacterial microbiota in a pediatric patient with chronic serous otitis media using 16SrRNA gene-based pyrosequencing
    Cindy M Liu
    Division of Pathogen Genomics, Translational Genomics Research Institute, Flagstaff, Arizona, USA
    Arch Otolaryngol Head Neck Surg 137:664-8. 2011
    ..To characterize bacterial microbiota in middle ear, adenoid, and tonsil specimens using 16SrRNA gene-based pyrosequencing analysis...
  15. pmc Molecular investigations of a locally acquired case of melioidosis in Southern AZ, USA
    David M Engelthaler
    Translational Genomics Research Institute, Flagstaff, Arizona, United States of America
    PLoS Negl Trop Dis 5:e1347. 2011
    ..Advancements in new typing technologies provide genotyping resolution not previously available to public health investigators, allowing for more accurate source identification...
  16. pmc High prevalence and two dominant host-specific genotypes of Coxiella burnetii in U.S. milk
    Talima Pearson
    Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, AZ 86011 4073, USA
    BMC Microbiol 14:41. 2014
    ..We collected A) 23 milk samples from a single bovine herd, B) 134 commercial bovine and caprine milk samples from across the U.S., and C) 400 bovine and caprine samples from six milk processing plants over three years...
  17. pmc Foodborne urinary tract infections: a new paradigm for antimicrobial-resistant foodborne illness
    Lora Nordstrom
    Division of Pathogen Genomics, Center for Food Microbiology and Environmental Health, The Translational Genomics Research Institute Flagstaff, AZ, USA
    Front Microbiol 4:29. 2013
    ..Along with this paradigm shift come new opportunities to disrupt the infection process and possibly quell increasing resistance, including the elimination of non-therapeutic antimicrobial use in food-animal production...
  18. pmc Genome analysis of Staphylococcus aureus ST291, a double locus variant of ST398, reveals a distinct genetic lineage
    Marc Stegger
    Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark
    PLoS ONE 8:e63008. 2013
    ..aureus ST398. However, whole genome sequencing show that ST291 is a unique genetic lineage with highly variable content within its accessory genome compared to both human and livestock associated genome sequenced CC398s...