Andrew Maier

Summary

Affiliation: Toxicology Excellence for Risk Assessment
Country: USA

Publications

  1. ncbi Arsenic co-exposure potentiates benzo[a]pyrene genotoxicity
    Andrew Maier
    Department of Environmental Health, Center for Environmental Genetics, University of Cincinnati Medical Center, P O Box 670056, Cincinnati, OH 45267, USA
    Mutat Res 517:101-11. 2002
  2. ncbi Critical review of dose-response options for F344 rat mammary tumors for acrylamide - additional insights based on mode of action
    Andrew Maier
    Toxicology Excellence for Risk Assessment, Cincinnati, OH 45211, United States
    Food Chem Toxicol 50:1763-75. 2012
  3. ncbi Evaluation of concentration-response options for diacetyl in support of occupational risk assessment
    Andrew Maier
    Toxicology Excellence for Risk Assessment, Cincinnati, OH 45211, USA
    Regul Toxicol Pharmacol 58:285-96. 2010
  4. ncbi Assessing biomarker use in risk assessment--a survey of practitioners
    Andrew Maier
    Toxicology Excellence for Risk Assessment, 1757 Chase Avenue, Cincinnati, OH 45223, USA
    J Toxicol Environ Health A 67:687-95. 2004
  5. ncbi Carcinogen biomonitoring in human exposures and laboratory research: validation and application to human occupational exposures
    Glenn Talaska
    The Department of Environmental Health, The University of Cincinnati College of Medicine, Cincinnati, OH 45267 0056, USA
    Toxicol Lett 134:39-49. 2002
  6. ncbi Derived Reference Doses (RfDs) for the environmental degradates of the herbicides alachlor and acetochlor: results of an independent expert panel deliberation
    Bernard Gadagbui
    Toxicology Excellence for Risk Assessment, Cincinnati, OH 45211, USA
    Regul Toxicol Pharmacol 57:220-34. 2010
  7. ncbi A Bayesian network model for biomarker-based dose response
    C Eric Hack
    Toxicology Excellence for Risk Assessment TERA, Cincinnati, OH, USA
    Risk Anal 30:1037-51. 2010
  8. ncbi Correlation of chemical structure with reproductive and developmental toxicity as it relates to the use of the threshold of toxicological concern
    Michael C Laufersweiler
    The Procter and Gamble Company, 11810 E Miami River Road, Cincinnati, OH 45040, USA
    Regul Toxicol Pharmacol 62:160-82. 2012
  9. ncbi Evaluation of human relevance and mode of action for tunica vaginalis mesotheliomas resulting from oral exposure to acrylamide
    Lynne T Haber
    Toxicology Excellence for Risk Assessment, 2300 Montana Avenue, Suite 409, Cincinnati, OH 45211, USA
    Regul Toxicol Pharmacol 53:134-49. 2009
  10. ncbi The evolution of skin notations for occupational risk assessment: a new NIOSH strategy
    G Scott Dotson
    Education and Information Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH 45227, USA
    Regul Toxicol Pharmacol 61:53-62. 2011

Detail Information

Publications15

  1. ncbi Arsenic co-exposure potentiates benzo[a]pyrene genotoxicity
    Andrew Maier
    Department of Environmental Health, Center for Environmental Genetics, University of Cincinnati Medical Center, P O Box 670056, Cincinnati, OH 45267, USA
    Mutat Res 517:101-11. 2002
    ..These results provide strong support for the positive interaction between arsenic and PAH-induced cancer observed in epidemiology studies, and help to identify additional mechanistic steps likely to be involved in arsenic comutagenesis...
  2. ncbi Critical review of dose-response options for F344 rat mammary tumors for acrylamide - additional insights based on mode of action
    Andrew Maier
    Toxicology Excellence for Risk Assessment, Cincinnati, OH 45211, United States
    Food Chem Toxicol 50:1763-75. 2012
    ..Comparison of the WOE for each alternative MOA indicates that a non-linear approach (option 2) is more appropriate for evaluation of acrylamide-induced mammary tumors; a linear approach (option 1) is shown for comparison...
  3. ncbi Evaluation of concentration-response options for diacetyl in support of occupational risk assessment
    Andrew Maier
    Toxicology Excellence for Risk Assessment, Cincinnati, OH 45211, USA
    Regul Toxicol Pharmacol 58:285-96. 2010
    ..2 ppm as a time-weighted average (TWA) was supported by the current occupational epidemiology literature. This evaluation showed that a health-based OEL value can be derived for diacetyl with moderate to high confidence...
  4. ncbi Assessing biomarker use in risk assessment--a survey of practitioners
    Andrew Maier
    Toxicology Excellence for Risk Assessment, 1757 Chase Avenue, Cincinnati, OH 45223, USA
    J Toxicol Environ Health A 67:687-95. 2004
    ....
  5. ncbi Carcinogen biomonitoring in human exposures and laboratory research: validation and application to human occupational exposures
    Glenn Talaska
    The Department of Environmental Health, The University of Cincinnati College of Medicine, Cincinnati, OH 45267 0056, USA
    Toxicol Lett 134:39-49. 2002
    ..These data reinforce the notion that carcinogen biomarkers are useful to monitor exposure, but that a complementary approaches involving effect and perhaps susceptibility biomarkers is necessary to obtain the necessary information...
  6. ncbi Derived Reference Doses (RfDs) for the environmental degradates of the herbicides alachlor and acetochlor: results of an independent expert panel deliberation
    Bernard Gadagbui
    Toxicology Excellence for Risk Assessment, Cincinnati, OH 45211, USA
    Regul Toxicol Pharmacol 57:220-34. 2010
    ..Based on the available data, an oral RfD of 0.2 mg/kg-day is recommended for both acetochlor ESA and acetochlor OXA and an oral RfD of 0.8 mg/kg-day is recommended for both alachlor ESA and alachlor OXA...
  7. ncbi A Bayesian network model for biomarker-based dose response
    C Eric Hack
    Toxicology Excellence for Risk Assessment TERA, Cincinnati, OH, USA
    Risk Anal 30:1037-51. 2010
    ..Such linkage can provide a scientifically valid point of departure that incorporates precursor dose-response information without being dependent on the difficult issue of a definition of adversity for precursors...
  8. ncbi Correlation of chemical structure with reproductive and developmental toxicity as it relates to the use of the threshold of toxicological concern
    Michael C Laufersweiler
    The Procter and Gamble Company, 11810 E Miami River Road, Cincinnati, OH 45040, USA
    Regul Toxicol Pharmacol 62:160-82. 2012
    ..The present analysis indicates that, for each Cramer Class, the reproductive and developmental endpoints would be protected at the corresponding general TTC tiers derived by Munro et al. (1996)...
  9. ncbi Evaluation of human relevance and mode of action for tunica vaginalis mesotheliomas resulting from oral exposure to acrylamide
    Lynne T Haber
    Toxicology Excellence for Risk Assessment, 2300 Montana Avenue, Suite 409, Cincinnati, OH 45211, USA
    Regul Toxicol Pharmacol 53:134-49. 2009
    ..In light of the very low incidence of TVMs in humans and the MOA data reviewed, the most appropriate upper bound estimate of the risk of acrylamide-related TVMs in humans is below de minimis levels...
  10. ncbi The evolution of skin notations for occupational risk assessment: a new NIOSH strategy
    G Scott Dotson
    Education and Information Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH 45227, USA
    Regul Toxicol Pharmacol 61:53-62. 2011
    ..The NIOSH strategy documents the scientific rationale for determination of the hazard potential of a chemical and the subsequent assignment of SKs. A case study of acrylamide is presented as an application of the NIOSH strategy...
  11. ncbi Scientific criteria used for the development of occupational exposure limits for metals and other mining-related chemicals
    Lynne T Haber
    Toxicology Excellence for Risk Assessment, Cincinnati, Ohio 45223, USA
    Regul Toxicol Pharmacol 36:262-79. 2002
    ....
  12. ncbi Resources for global risk assessment: the International Toxicity Estimates for Risk (ITER) and Risk Information Exchange (RiskIE) databases
    Andrea Wullenweber
    Toxicology Excellence for Risk Assessment, 2300 Montana Avenue, Suite 409, Cincinnati, OH 45211, USA
    Toxicol Appl Pharmacol 233:45-53. 2008
    ....
  13. ncbi An approach for the quantitative consideration of genetic polymorphism data in chemical risk assessment: examples with warfarin and parathion
    P Robinan Gentry
    ENVIRON International Corporation, 602 East Georgia Avenue, Ruston, Louisiana 71270 Toxicology Excellence for Risk Assessment, Cincinnati, Ohio 45223, USA
    Toxicol Sci 70:120-39. 2002
    ..Implications of alternatives in the calculation of CSAFs are explored. Key decision points for applying the PBPK-Monte Carlo approach to evaluate toxicokinetic variability for other chemicals are also discussed...
  14. ncbi Role of the aryl hydrocarbon receptor in cell cycle regulation
    Alvaro Puga
    Department of Environmental Health, University of Cincinnati Medical Center, P O Box 670056, 123 E Shields Street, Cincinnati, OH 45267 0056, USA
    Toxicology 181:171-7. 2002
    ..The activated receptor acts as an environmental sensor and cell cycle checkpoint that commits cells exposed to adverse environmental stimuli to arrest before the onset of DNA replication...
  15. ncbi Application of the threshold of toxicological concern concept to pharmaceutical manufacturing operations
    David G Dolan
    Occupational and Environmental Health Sciences, Merck and Co, Inc, Whitehouse Station, NJ 08889 0200, USA
    Regul Toxicol Pharmacol 43:1-9. 2005
    ..Corresponding ADIs for these categories of materials are 1, 10, and 100 microg/day, respectively...