Petra A Tsuji

Summary

Affiliation: Towson University
Country: USA

Publications

  1. doi request reprint Dietary Selenium Levels Affect Selenoprotein Expression and Support the Interferon-γ and IL-6 Immune Response Pathways in Mice
    Petra A Tsuji
    Department of Biological Sciences, Towson University, Towson, MD, 21252, USA
    Nutrients 7:6529-49. 2015
  2. pmc Knockout of the 15 kDa selenoprotein protects against chemically-induced aberrant crypt formation in mice
    Petra A Tsuji
    Department of Biological Sciences, Towson University, Towson, Maryland, United States of America
    PLoS ONE 7:e50574. 2012
  3. pmc Deficiency in the 15 kDa selenoprotein inhibits human colon cancer cell growth
    Petra A Tsuji
    Cancer Prevention Fellowship Program, National Cancer Institute, Rockville, MD 20892, USA
    Nutrients 3:805-17. 2011
  4. pmc Deficiency in the 15-kDa selenoprotein inhibits tumorigenicity and metastasis of colon cancer cells
    Robert Irons
    Nutritional Science Research Group, Molecular Biology of Selenium Section, Laboratory of Cancer Prevention, National Cancer Institute, Rockville, MD 20892 7328, USA
    Cancer Prev Res (Phila) 3:630-9. 2010
  5. pmc Regulation of HIF-1α activity by overexpression of thioredoxin is independent of thioredoxin reductase status
    Salvador Naranjo-Suarez
    Molecular Biology of Selenium Section, Laboratory of Cancer Prevention, Center for Cancer Research, National Institutes of Health, Bethesda, MD 20892, USA
    Mol Cells 36:151-7. 2013
  6. pmc The 15kDa selenoprotein and thioredoxin reductase 1 promote colon cancer by different pathways
    Petra A Tsuji
    Department of Biological Sciences, Towson University, Towson, Maryland, United States of America
    PLoS ONE 10:e0124487. 2015
  7. pmc HIF-independent regulation of thioredoxin reductase 1 contributes to the high levels of reactive oxygen species induced by hypoxia
    Salvador Naranjo-Suarez
    Molecular Biology of Selenium Section, Laboratory of Cancer Prevention, National Cancer Institute, Bethesda, Maryland, United States of America
    PLoS ONE 7:e30470. 2012
  8. pmc Mouse models targeting selenocysteine tRNA expression for elucidating the role of selenoproteins in health and development
    Bradley A Carlson
    Molecular Biology of Selenium Section, Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Molecules 14:3509-27. 2009
  9. doi request reprint Selenoproteins and cancer prevention
    Cindy D Davis
    Nutritional Science Research Group, National Cancer Institute, Rockville, Maryland 20892, USA
    Annu Rev Nutr 32:73-95. 2012

Collaborators

Detail Information

Publications9

  1. doi request reprint Dietary Selenium Levels Affect Selenoprotein Expression and Support the Interferon-γ and IL-6 Immune Response Pathways in Mice
    Petra A Tsuji
    Department of Biological Sciences, Towson University, Towson, MD, 21252, USA
    Nutrients 7:6529-49. 2015
    ..These data are consistent with previous reports indicating that adequate selenium levels can support beneficial immune responses, and further identify the IL-6 and interferon-γ pathways as being responsive to dietary selenium intake. ..
  2. pmc Knockout of the 15 kDa selenoprotein protects against chemically-induced aberrant crypt formation in mice
    Petra A Tsuji
    Department of Biological Sciences, Towson University, Towson, Maryland, United States of America
    PLoS ONE 7:e50574. 2012
    ..Overall, our results demonstrate for the first time, that Sep15 knockout mice are protected against chemically-induced aberrant crypt foci formation and that Sep15 appears to have oncogenic properties in colon carcinogenesis in vivo...
  3. pmc Deficiency in the 15 kDa selenoprotein inhibits human colon cancer cell growth
    Petra A Tsuji
    Cancer Prevention Fellowship Program, National Cancer Institute, Rockville, MD 20892, USA
    Nutrients 3:805-17. 2011
    ..The potential mechanism by which human colon cancer cells lacking Sep15 revert their cancer phenotype will need to be explored further...
  4. pmc Deficiency in the 15-kDa selenoprotein inhibits tumorigenicity and metastasis of colon cancer cells
    Robert Irons
    Nutritional Science Research Group, Molecular Biology of Selenium Section, Laboratory of Cancer Prevention, National Cancer Institute, Rockville, MD 20892 7328, USA
    Cancer Prev Res (Phila) 3:630-9. 2010
    ..These data suggest tissue specificity in the cancer-protective effects of Sep15 downregulation, which are mediated, at least in part, by influencing the cell cycle...
  5. pmc Regulation of HIF-1α activity by overexpression of thioredoxin is independent of thioredoxin reductase status
    Salvador Naranjo-Suarez
    Molecular Biology of Selenium Section, Laboratory of Cancer Prevention, Center for Cancer Research, National Institutes of Health, Bethesda, MD 20892, USA
    Mol Cells 36:151-7. 2013
    ..Thus, regulation of HIF-1α by the thioredoxin system depends on the specific levels of this system's major components...
  6. pmc The 15kDa selenoprotein and thioredoxin reductase 1 promote colon cancer by different pathways
    Petra A Tsuji
    Department of Biological Sciences, Towson University, Towson, Maryland, United States of America
    PLoS ONE 10:e0124487. 2015
    ..Considering the variable expression levels of Sep15 and TR1 found within the human population, our results provide insights into new roles of selenoproteins in cancer. ..
  7. pmc HIF-independent regulation of thioredoxin reductase 1 contributes to the high levels of reactive oxygen species induced by hypoxia
    Salvador Naranjo-Suarez
    Molecular Biology of Selenium Section, Laboratory of Cancer Prevention, National Cancer Institute, Bethesda, Maryland, United States of America
    PLoS ONE 7:e30470. 2012
    ..These results indicate that hypoxic TR1 down-regulation is important in maintaining high levels of ROS under hypoxic conditions and that HIF stabilization and activity do not require hypoxic generation of ROS...
  8. pmc Mouse models targeting selenocysteine tRNA expression for elucidating the role of selenoproteins in health and development
    Bradley A Carlson
    Molecular Biology of Selenium Section, Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Molecules 14:3509-27. 2009
    ....
  9. doi request reprint Selenoproteins and cancer prevention
    Cindy D Davis
    Nutritional Science Research Group, National Cancer Institute, Rockville, Maryland 20892, USA
    Annu Rev Nutr 32:73-95. 2012
    ....