Alison A McCormickSummaryAffiliation: Touro University Country: USA Publications
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Genetically engineered Tobacco mosaic virus as nanoparticle vaccinesAlison A McCormick
Touro University of California, College of Pharmacy, Vallejo, CA 94592, USA
Expert Rev Vaccines 7:33-41. 2008..Lastly, we describe how TMV self-assembly properties are being used to make a new mammalian RNA pseudovirus, that has unique characteristics for RNA and protein antigen delivery to antigen-presenting cells...
Modified tobacco mosaic virus particles as scaffolds for display of protein antigens for vaccine applicationsMark L Smith
Large Scale Biology Corporation, Vacaville, CA 95688, USA
Virology 348:475-88. 2006..By demonstrating the presentation of whole proteins, this study expands the utility of TMV as a vaccine scaffold beyond that which is possible by genetic manipulation...
Individualized human scFv vaccines produced in plants: humoral anti-idiotype responses in vaccinated mice confirm relevance to the tumor IgAlison A McCormick
Large Scale Biology Corporation, Vacaville, CA 95688, USA
J Immunol Methods 278:95-104. 2003..Four out of four anti-scFv sera were also shown to recognize the Ig on human tumor cells by flow cytometry analysis...
Protection of rabbits against cutaneous papillomavirus infection using recombinant tobacco mosaic virus containing L2 capsid epitopesKenneth E Palmer
Large Scale Biology Corporation, 3333 Vaca Valley Parkway, Vacaville, CA 95688, USA
Vaccine 24:5516-25. 2006..Finally, the study demonstrated that rTMV were excellent agents for the induction of strong protection in a pre-clinical disease model of papillomavirus infection...
TMV-peptide fusion vaccines induce cell-mediated immune responses and tumor protection in two murine modelsAlison A McCormick
Large Scale Biology Corporation, Vaccine Development, Vacaville, CA 95688, USA
Vaccine 24:6414-23. 2006..7-Ova and B16 melanoma models. From these results we conclude that TMV was an effective antigen carrier for inducing cellular immune responses to less than 1 microg of peptide...
Chemical conjugate TMV-peptide bivalent fusion vaccines improve cellular immunity and tumor protectionAlison A McCormick
Large Scale Biology Corporation, 3333 Vacavalley Parkway, Suite 1000, Vacaville, California 95688, USA
Bioconjug Chem 17:1330-8. 2006..Interestingly, different bivalent vaccine formulations were required to improve vaccine efficacy for Ova or melanoma tumor model systems...
Assembly of trans-encapsidated recombinant viral vectors engineered from Tobacco mosaic virus and Semliki Forest virus and their evaluation as immunogensMark L Smith
Large Scale Biology Corporation, 3333 Vaca Valley Parkway, Suite 1000, Vacaville, CA 95688, USA
Virology 358:321-33. 2007..The SFV vector/TMV CP system described provides an alternative nucleic acid delivery mechanism that is safe, easy to manufacture in vitro and that also facilitates the generation of unique nucleic acid/protein antigen compositions...
