EDWARD P WINTER
Affiliation: Thomas Jefferson University
- The Sum1/Ndt80 transcriptional switch and commitment to meiosis in Saccharomyces cerevisiaeEdward Winter
Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Microbiol Mol Biol Rev 76:1-15. 2012..The conservation of regulatory components of the meiotic commitment pathway and the recently reported ability of Ndt80 to increase replicative life span are discussed...
- The Cdk1 and Ime2 protein kinases trigger exit from meiotic prophase in Saccharomyces cerevisiae by inhibiting the Sum1 transcriptional repressorMarcus E Shin
Department of Biochemistry and Molecular Biology, Thomas Jefferson University, 233 South 10th Street, Philadelphia, PA 19107, USA
Mol Cell Biol 30:2996-3003. 2010..These results demonstrate that Sum1 functions as a key meiotic brake through the NDT80 promoter and that Cdk1 and Ime2 trigger exit from meiotic prophase by inhibiting the Sum1 transcriptional repression complex...
- PROTEIN KINASE NETWORKS AND SPORULATION IN S. CEREVISIAEEDWARD P WINTER; Fiscal Year: 2010..These studies will provide mechanistic insights into how protein kinase networks control developmental programs in general and meiotic development in particular. ..
- A transcriptional switch that controls meiosisEDWARD P WINTER; Fiscal Year: 2010..These studies will elucidate new molecular mechanisms that regulate meiotic development in particular and differentiation programs in general. ..
- THE SMKI MAPK AND SPORE DEVELOPMENT IN SACCHAROMYCESEdward Winter; Fiscal Year: 2003..Cell. Biol. 18:5970, i.e. et al. EMO J. in press). In aim 4 experiments are described that will: Elucidate the role of the SMK1 transcriptional regulatory pathway in controlling progression of meiotic development. ..