Michael R Sperling

Summary

Affiliation: Thomas Jefferson University
Country: USA

Publications

  1. ncbi request reprint EEG reading session
    Michael R Sperling
    Department of Neurology, Thomas Jefferson University, Jefferson Comprehensive Epilepsy Center, Philadelphia, Pennsylvania 19107, USA
    J Clin Neurophysiol 23:230-7. 2006
  2. ncbi request reprint Seizures and brain tumors
    Michael R Sperling
    Department of Neurology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Semin Oncol 33:333-41. 2006
  3. ncbi request reprint Prognosis after late relapse following epilepsy surgery
    Michael R Sperling
    Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, PA 19107, United States
    Epilepsy Res 78:77-81. 2008
  4. ncbi request reprint Self-perception of seizure precipitants and their relation to anxiety level, depression, and health locus of control in epilepsy
    Michael R Sperling
    Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, 900 Walnut Street, Suite 200, Philadelphia, PA 19107, United States
    Seizure 17:302-7. 2008
  5. doi request reprint Carisbamate as adjunctive treatment of partial onset seizures in adults in two randomized, placebo-controlled trials
    Michael R Sperling
    Jefferson Comprehensive Epilepsy Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Epilepsia 51:333-43. 2010
  6. ncbi request reprint The necessity for sphenoidal electrodes in the presurgical evaluation of temporal lobe epilepsy: pro position
    Michael R Sperling
    Department of Neurology, Jefferson Medical Callege, and Jefferson Comprehensive Epilepsy Center, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107, USA
    J Clin Neurophysiol 20:299-304. 2003
  7. ncbi request reprint The consequences of uncontrolled epilepsy
    Michael R Sperling
    Department of Neurology, Comprehensive Epilepsy Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    CNS Spectr 9:98-101, 106-9. 2004
  8. ncbi request reprint Latency to first seizure after temporal lobectomy predicts long-term outcome
    Sarah E Buckingham
    Jefferson Medical College, Philadelphia, Pennsylvania, USA
    Epilepsia 51:1987-93. 2010
  9. doi request reprint Antiepileptic drugs and relapse after epilepsy surgery
    Ali A Asadi-Pooya
    Jefferson Comprehensive Epilepsy Center, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Epileptic Disord 10:193-8. 2008
  10. doi request reprint Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial
    Jerome Engel
    Department of Neurology, David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Los Angeles, CA 90095 1769, USA
    JAMA 307:922-30. 2012

Detail Information

Publications75

  1. ncbi request reprint EEG reading session
    Michael R Sperling
    Department of Neurology, Thomas Jefferson University, Jefferson Comprehensive Epilepsy Center, Philadelphia, Pennsylvania 19107, USA
    J Clin Neurophysiol 23:230-7. 2006
  2. ncbi request reprint Seizures and brain tumors
    Michael R Sperling
    Department of Neurology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Semin Oncol 33:333-41. 2006
    ..Prophylactic anticonvulsant treatment is not advisable in brain tumor patients who have not experienced seizures...
  3. ncbi request reprint Prognosis after late relapse following epilepsy surgery
    Michael R Sperling
    Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, PA 19107, United States
    Epilepsy Res 78:77-81. 2008
    ..To assess prognosis after late relapse in patients who are seizure free for the first 5 years after epilepsy surgery...
  4. ncbi request reprint Self-perception of seizure precipitants and their relation to anxiety level, depression, and health locus of control in epilepsy
    Michael R Sperling
    Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, 900 Walnut Street, Suite 200, Philadelphia, PA 19107, United States
    Seizure 17:302-7. 2008
    ....
  5. doi request reprint Carisbamate as adjunctive treatment of partial onset seizures in adults in two randomized, placebo-controlled trials
    Michael R Sperling
    Jefferson Comprehensive Epilepsy Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Epilepsia 51:333-43. 2010
    ..To assess the efficacy, safety, and tolerability of the investigational drug carisbamate as adjunctive treatment for partial-onset seizures (POS)...
  6. ncbi request reprint The necessity for sphenoidal electrodes in the presurgical evaluation of temporal lobe epilepsy: pro position
    Michael R Sperling
    Department of Neurology, Jefferson Medical Callege, and Jefferson Comprehensive Epilepsy Center, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107, USA
    J Clin Neurophysiol 20:299-304. 2003
    ..Sphenoidal electrodes may spare some patients unnecessary intracranial electrode investigation and permit surgery for others...
  7. ncbi request reprint The consequences of uncontrolled epilepsy
    Michael R Sperling
    Department of Neurology, Comprehensive Epilepsy Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    CNS Spectr 9:98-101, 106-9. 2004
    ..Treatment should be directed to preventing seizures whenever possible and achieving control early in the course of illness. The risks of uncontrolled seizures outweigh the risks of aggressive medical or surgical therapy...
  8. ncbi request reprint Latency to first seizure after temporal lobectomy predicts long-term outcome
    Sarah E Buckingham
    Jefferson Medical College, Philadelphia, Pennsylvania, USA
    Epilepsia 51:1987-93. 2010
    ..Little is known about the prognostic significance of the time from surgery to first seizure relapse in predicting long-term outcome...
  9. doi request reprint Antiepileptic drugs and relapse after epilepsy surgery
    Ali A Asadi-Pooya
    Jefferson Comprehensive Epilepsy Center, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Epileptic Disord 10:193-8. 2008
    ..To evaluate whether the postoperative, antiepileptic drug (AED) regimen influences seizure recurrence after anterior temporal lobectomy when considering the putative mechanism of action and possible neuroprotective effects...
  10. doi request reprint Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial
    Jerome Engel
    Department of Neurology, David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Los Angeles, CA 90095 1769, USA
    JAMA 307:922-30. 2012
    ..Despite reported success, surgery for pharmacoresistant seizures is often seen as a last resort. Patients are typically referred for surgery after 20 years of seizures, often too late to avoid significant disability and premature death...
  11. pmc Design considerations for a multicenter randomized controlled trial of early surgery for mesial temporal lobe epilepsy
    Jerome Engel
    Department of Neurology, UCLA, Los Angeles, California 90095 1769, USA
    Epilepsia 51:1978-86. 2010
    ..ERSET was designed to assess the safety and efficacy of early surgical intervention compared to continued pharmacotherapy...
  12. ncbi request reprint Health locus of control in patients with epilepsy and its relationship to anxiety, depression, and seizure control
    Ali A Asadi-Pooya
    Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, PA, USA
    Epilepsy Behav 11:347-50. 2007
    ..The aim of this study was to determine the health locus of control in patients with epilepsy and its relationship to anxiety, depression, and seizure control...
  13. doi request reprint Hemispheric lateralization and language skill coherence in temporal lobe epilepsy
    Joseph I Tracy
    Department of Neurology, Thomas Jefferson University, Jefferson Medical College, Philadelphia, PA 19107, United States
    Cortex 45:1178-89. 2009
    ..There was also evidence that language is not monolithic with all language skills reorganizing together. The latter suggests that the pressures compelling atypical representation may not work equally on all language skills...
  14. doi request reprint Postoperative auras and the risk of recurrent seizures
    Thenappan Chandrasekar
    Comprehensive Epilepsy Center, Thomas Jefferson University, Philadelphia, PA, United States
    Epilepsy Res 78:195-200. 2008
    ..Little is known about the prognostic significance of persistent auras following temporal lobe surgery in determining the recurrence of complex partial seizures (CPS) or generalized tonic-clonic seizures (GTCS)...
  15. ncbi request reprint Corpus callosotomy in refractory idiopathic generalized epilepsy
    Sigmund Jenssen
    Drexel Medical College, Neurology, Hahnemann University Hospital, Broad and Vine Streets, Philadelphia, PA 19102 1192, USA
    Seizure 15:621-9. 2006
    ..Generalized tonic-clonic (GTC) seizures are especially debilitating and can be associated with severe injuries. The benefit, safety and effect of corpus callosotomy (CC) in patients with IGE have not been studied...
  16. ncbi request reprint The effectiveness of low-frequency stimulation for mapping cortical function
    Andro Zangaladze
    Department of Neurology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Epilepsia 49:481-7. 2008
    ..To establish the efficacy and safety of low-frequency electrical stimulation for cortical brain mapping...
  17. pmc Seizure recurrence and remission after switching antiepileptic drugs
    Sophia Pan Wang
    Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Epilepsia 54:187-93. 2013
    ..We aimed to address both of these issues using a matched case-cohort design...
  18. ncbi request reprint Value of non-invasive testing when there are independent bitemporal seizures in the scalp EEG
    Sigmund Jenssen
    Department of Neurology, Drexel Medical College, Hahnemann University Hospital, Mail Stop 423, Broad and Vine Streets, Philadelphia, PA 19129, USA
    Epilepsy Res 68:115-22. 2006
    ..These findings need confirmation...
  19. ncbi request reprint Predicting seizure frequency after epilepsy surgery
    John S Khoury
    Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Epilepsy Res 67:89-99. 2005
    ..To identify clinical features related to seizure frequency after epilepsy surgery in patients with recurrent seizures...
  20. pmc Hippocampal volumetry and functional MRI of memory in temporal lobe epilepsy
    Dawn Mechanic-Hamilton
    Center for Functional Neuroimaging, University of Pennsylvania, Philadelphia, PA, USA
    Epilepsy Behav 16:128-38. 2009
    ..These findings support continued investigation of the utility of MRI and fMRI in the presurgical evaluation of TLE...
  21. ncbi request reprint Strategies for surgical treatment of epilepsies in developing countries
    Ali A Asadi-Pooya
    Jefferson Comprehensive Epilepsy Center, Neurology Department, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Epilepsia 49:381-5. 2008
    ..These operations are feasible in developing countries with a knowledgeable team consisting of an epileptologist, neurosurgeon and technicians and with using MRI and EEG as basic investigative technologies...
  22. doi request reprint Conversion from enzyme-inducing antiepileptic drugs to topiramate: effects on lipids and C-reactive protein
    Scott Mintzer
    Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadephia, PA, United States
    Epilepsy Res 98:88-93. 2012
    ..We also examined the effects of drug switch on low-density lipoprotein (LDL) particle concentration...
  23. doi request reprint Characteristics and clinical significance of subclinical seizures
    Andro Zangaladze
    Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, Pennsylvania USA
    Epilepsia 49:2016-21. 2008
    ..To define characteristics of subclinical seizures (SCS) and their prognostic significance after epilepsy surgery...
  24. pmc Direct recordings of grid-like neuronal activity in human spatial navigation
    Joshua Jacobs
    School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, Pennsylvania, USA
    Nat Neurosci 16:1188-90. 2013
    ....
  25. pmc An investigation of implicit memory through left temporal lobectomy for epilepsy
    Joseph I Tracy
    Department of Neurology, Thomas Jefferson University, Jefferson Medical College, United States
    Neurobiol Learn Mem 98:272-83. 2012
    ..Our data suggest that a healthy mesial/anterior temporal lobe may be needed for generating the posterior deactivation perceptual priming response seen in normals...
  26. doi request reprint Surgical outcome in PET-positive, MRI-negative patients with temporal lobe epilepsy
    Carla Lopinto-Khoury
    Department of Neurology Neurosurgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Epilepsia 53:342-8. 2012
    ..We examined surgical outcomes in a group of PET-positive, MRI-negative patients and compared them with those of patients with MTS...
  27. ncbi request reprint Are depression and cognitive performance related in temporal lobe epilepsy?
    Joseph I Tracy
    Department of Neurology, Comprehensive Epilepsy Center, Thomas Jefferson University Hospital Jefferson Medical College, Philadelphia, Pennsylvania 19107, USA
    Epilepsia 48:2327-35. 2007
    ..Temporal lobe epilepsy (TLE) patients are known to possess cognitive dysfunction. Thus, TLE patients who are depressed may suffer a double burden of cognitive deficits...
  28. doi request reprint Intracarotid amobarbital procedure for epilepsy surgery
    Ashwini Sharan
    Department of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Epilepsy Behav 20:209-13. 2011
    ..This article summarizes a debate that took place during the 2009 American Epilepsy Society (AES) annual course...
  29. pmc The functional anatomy of non-verbal (pitch memory) function in left and right anterior temporal lobectomy patients
    Joseph I Tracy
    Department of Neurology, Thomas Jefferson University Jefferson Medical College, Philadelphia, PA 19107, USA
    Clin Neurol Neurosurg 115:934-43. 2013
    ..While our data clarifies the functional neuroanatomy of pitch memory, it also indicates that such tasks do not serve well to lateralize and functionally map potentially "at risk" non-verbal memory skills prior to ATL...
  30. doi request reprint B-vitamin deficiency in patients treated with antiepileptic drugs
    Scott Mintzer
    Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, PA, USA
    Epilepsy Behav 24:341-4. 2012
    ..This could conceivably contribute to the polyneuropathy sometimes attributed to older AEDs, as well as other chronic heath difficulties...
  31. ncbi request reprint Refractory generalized seizures: response to corpus callosotomy and vagal nerve stimulation
    Maromi Nei
    Department of Neurology, Jefferson Medical College, Philadelphia, PA, USA
    Epilepsia 47:115-22. 2006
    ..However, the efficacy and safety of these two procedures have not been compared. This study evaluates the two procedures for generalized seizures...
  32. doi request reprint Corpus callosotomy
    Ali A Asadi-Pooya
    Jefferson Comprehensive Epilepsy Center, Neurology Department, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Epilepsy Behav 13:271-8. 2008
    ..In addition to seizure reduction, behavior and quality of life may improve. Hence, callosotomy is justified as a therapy for appropriate patients with intractable epilepsy...
  33. ncbi request reprint Mortality after epilepsy surgery
    Michael R Sperling
    Department of Neurology, Jefferson Comprehensive Epilepsy Center, Thomas Jefferson University, Philadelphia, 19107, USA
    Epilepsia 46:49-53. 2005
    ..These data show that the excess mortality associated with refractory epilepsy is eliminated after epilepsy surgery when seizures are abolished and suggest that epilepsy surgery reduces the risk of epilepsy-associated death...
  34. ncbi request reprint How long do most seizures last? A systematic comparison of seizures recorded in the epilepsy monitoring unit
    Sigmund Jenssen
    Department of Neurology, Drexel Medical College, Philadelphia, PA, USA
    Epilepsia 47:1499-503. 2006
    ..More information is needed regarding how long seizures typically last, since this influences treatment decisions. Seizure type and other factors could influence seizure duration...
  35. ncbi request reprint Subjective somnolence relates mainly to depression among patients in a tertiary care epilepsy center
    Sigmund Jenssen
    Department of Neurology, Drexel Medical College, Broad and Vine Streets, Hahnemann University Hospital, Mail Stop 308, Philadelphia, PA 19107, USA
    Epilepsy Behav 9:632-5. 2006
    ..Further investigation is needed into the relationship between depression and subjective somnolence in patients with epilepsy...
  36. pmc Functional connectivity evidence of cortico-cortico inhibition in temporal lobe epilepsy
    Joseph I Tracy
    Department of Neurology, Thomas Jefferson University, Philadelphia, Pennsylvania
    Hum Brain Mapp 35:353-66. 2014
    ..Hum Brain Mapp 35:353-366, 2014. © 2012 Wiley Periodicals, Inc. ..
  37. pmc Synchronous and asynchronous theta and gamma activity during episodic memory formation
    John F Burke
    Neuroscience Graduate Group, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Neurosci 33:292-304. 2013
    ..We show that these two kinds of spectral modulations have distinct spatiotemporal profiles during memory encoding...
  38. doi request reprint Employment after anterior temporal lobectomy
    Katherine Zarroli
    Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Epilepsia 52:925-31. 2011
    ..To explore the effect of anterior temporal lobectomy on employment and define demographic and clinical predictors of postoperative employment in a large cohort with a prolonged observational period...
  39. ncbi request reprint Interictal EEG and the diagnosis of epilepsy
    Jyoti Pillai
    Department of Neurology, Drexel College of Medicine, Philadelphia, Pennsylvania, USA
    Epilepsia 47:14-22. 2006
    ..Nonetheless, in skilled hands, it provides unique and vital information in many patients, and enhances our understanding of their condition...
  40. doi request reprint When should a resection sparing mesial structures be considered for temporal lobe epilepsy?
    Scott Mintzer
    Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, PA, USA
    Epilepsy Behav 13:7-11. 2008
    ..There is a clear need to move beyond the field's present focus on the hippocampus and investigate new approaches to TLE that may minimize the risks of functional consequences in patients without HS...
  41. doi request reprint Treatment of status epilepticus: an international survey of experts
    James J Riviello
    NYU Comprehensive Epilepsy Center, NYU Langone Medical Center, Division of Pediatric Neurology, Department of Neurology, New York University School of Medicine, 223 East 34th Street, New York, NY 10016, USA
    Neurocrit Care 18:193-200. 2013
    ..As part of the development of the Neurocritical Care Society (NCS) Status Epilepticus (SE) Guidelines, the NCS SE Writing Committee conducted an international survey of SE experts...
  42. doi request reprint Impedance variations over time for a closed-loop neurostimulation device: early experience with chronically implanted electrodes
    Chengyuan Wu
    Department of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Neuromodulation 16:46-50; discussion 50. 2013
    ..We analyzed impedance values over time to gain a better understanding of RNS device stability, potential differences between depth and strip electrodes, and general implications of long-term electrode implantation...
  43. pmc Extratemporal functional connectivity impairments at rest are related to memory performance in mesial temporal epilepsy
    Gaëlle Doucet
    Department of Neurology, Cognitive Neuroscience and Brain Imaging Laboratory, Thomas Jefferson University, Jefferson Medical College, 901 Walnut St, Philadelphia, PA 19107, USA
    Hum Brain Mapp 34:2202-16. 2013
    ..Our data also indicates that the pattern of extra-temporal FC may vary as a function of episodic memory material and each hemisphere's capacity for cognitive reorganization...
  44. ncbi request reprint Health-related quality of life over time since resective epilepsy surgery
    Susan S Spencer
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06520 8018, USA
    Ann Neurol 62:327-34. 2007
    ..Health-related quality of life (HRQOL) improves after resective epilepsy surgery, but data are limited to short follow-up in mostly retrospective reports, with minimal consideration of other potential factors that might influence HRQOL...
  45. ncbi request reprint Do foods precipitate seizures? A cross-cultural comparison
    Ali A Asadi-Pooya
    Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Epilepsy Behav 11:450-3. 2007
    ..Our aim in the present study was to ascertain whether a culturally different population of patients with epilepsy in the United States believe that foods precipitate seizures...
  46. doi request reprint Sporadic hemiplegic migraine and epilepsy associated with CACNA1A gene mutation
    Andro Zangaladze
    Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Epilepsy Behav 17:293-5. 2010
    ....
  47. doi request reprint Nutritional supplements, foods, and epilepsy: is there a relationship?
    Ali A Asadi-Pooya
    Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Epilepsia 49:1819-27. 2008
    ..This paper reviews dietary and nutritional considerations in patients with epilepsy and also the relationship between foods, dietary elements, and seizures...
  48. doi request reprint Effects of antiepileptic drugs on lipids, homocysteine, and C-reactive protein
    Scott Mintzer
    Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Ann Neurol 65:448-56. 2009
    ..We sought to determine whether these drugs have an effect on cholesterol and other serological markers of vascular risk...
  49. pmc Functional connectivity abnormalities vary by amygdala subdivision and are associated with psychiatric symptoms in unilateral temporal epilepsy
    Gaëlle E Doucet
    Department of Neurology, Thomas Jefferson University, United States Department of Neurosurgery, Thomas Jefferson University, United States
    Brain Cogn 83:171-82. 2013
    ..Overall, our data demonstrate that right TLE has a more maladaptive impact on emotion-related networks, in ways specific to the amygdala region, and the emotion symptom involved, than left TLE. ..
  50. pmc Hippocampal functional connectivity patterns during spatial working memory differ in right versus left temporal lobe epilepsy
    Gaëlle Doucet
    Department of Neurology, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Brain Connect 3:398-406. 2013
    ..More broadly, our findings demonstrate that FC methods applied to task-based fMRI provide the opportunity to define specific task-related networks...
  51. doi request reprint Twiddler's syndrome in a patient with epilepsy treated with deep brain stimulation
    David L Penn
    Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Epilepsia 53:e119-21. 2012
    ..In conclusion, twiddler's syndrome is a rare complication occurring in patients with deep brain stimulator implants and warrants awareness among neurologic and neurosurgical epilepsy specialists...
  52. doi request reprint Long-term cardiac rhythm and repolarization abnormalities in refractory focal and generalized epilepsy
    Maromi Nei
    Department of Neurology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107, USA
    Epilepsia 53:e137-40. 2012
    ..Patients with Lennox-Gastaut syndrome may be at high risk for cardiac abnormalities...
  53. ncbi request reprint EEG and ECG in sudden unexplained death in epilepsy
    Maromi Nei
    Jefferson Comprehensive Epilepsy Center, Department of Neurology, Jefferson Medical College, Philadelphia, Pennsylvania, USA
    Epilepsia 45:338-45. 2004
    ..Sudden unexpected death in epilepsy (SUDEP) is a major cause of mortality for patients with epilepsy. Cardiac factors may be involved and were evaluated in this study...
  54. doi request reprint Clinical features of sudden unexpected death in epilepsy
    Ali A Asadi-Pooya
    Department of Neurology, Jefferson Comprehensive Epilepsy Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    J Clin Neurophysiol 26:297-301. 2009
    ..This article reviews the clinical features associated with SUDEP and suggests preventive measures for this condition...
  55. pmc Repeated stimuli elicit diminished high-gamma electrocorticographic responses
    Anna Rodriguez Merzagora
    School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, USA
    Neuroimage 85:844-52. 2014
    ..These results have implications for understanding the neural basis of RS and human memory by showing that individual cortical sites exhibit the largest RS for the stimuli that they most actively represent. ..
  56. ncbi request reprint Functional MRI predicts post-surgical memory following temporal lobectomy
    Marcie L Rabin
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Brain 127:2286-98. 2004
    ....
  57. ncbi request reprint Potentiation of anti-epileptic drugs effectiveness by pyronaridine in refractory epilepsy
    Ali Akbar Asadi-Pooya
    Jefferson Comprehensive Epilepsy Center, Thomas Jefferson University, Philadelphia, PA, USA
    Med Hypotheses 69:560-3. 2007
    ....
  58. doi request reprint Genetic risk perception and reproductive decision making among people with epilepsy
    Katherine L Helbig
    Genetic Counseling Program, Arcadia University, Glenside, Pennsylvania, USA
    Epilepsia 51:1874-7. 2010
    ..The mean estimated risk of offspring to develop epilepsy was 26%, a 4-fold increase over estimated population risks. Genetic counseling may be beneficial for people with epilepsy, given the considerable overestimation of offspring risk...
  59. ncbi request reprint A comparison of surgical and medical costs for refractory epilepsy
    Michael Platt
    Department of Neurology, Jefferson Medical College, Philadelphia, Pennsylvania 19107, USA
    Epilepsia 43:25-31. 2002
  60. ncbi request reprint Temporal lobectomy
    Michael R Sperling
    Thomas Jefferson University Hospital, 111 S 11th St, Philadelphia, PA 19107, USA
    Arch Neurol 59:482-4. 2002
    ..The inadequacy of medical therapy led to the development of effective neurosurgical procedures, and this article cites several seminal authors who pioneered the development of the field...
  61. doi request reprint Adjunctive use of verapamil in patients with refractory temporal lobe epilepsy: a pilot study
    Ali A Asadi-Pooya
    Department of Neurology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, USA Electronic address
    Epilepsy Behav 29:150-4. 2013
    ..The present study aimed to determine if adjunctive use of verapamil, as a P-glycoprotein (P-gp) inhibitor, is efficacious in decreasing seizure frequency in patients with refractory temporal lobe epilepsy...
  62. doi request reprint A clinical study of syndromes of idiopathic (genetic) generalized epilepsy
    Ali A Asadi-Pooya
    Neurosciences Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
    J Neurol Sci 324:113-7. 2013
    ....
  63. doi request reprint Intracranial EEG in predicting surgical outcome in frontal lobe epilepsy
    Martin Holtkamp
    Epilepsie Zentrum Berlin Brandenburg, Department of Neurology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Epilepsia 53:1739-45. 2012
    ..The current study aimed to assess whether intracranial interictal and ictal EEG findings in addition to clinical and scalp EEG data help to predict outcome in a series of patients who needed invasive recording for FLE surgery...
  64. pmc Spontaneously reactivated patterns in frontal and temporal lobe predict semantic clustering during memory search
    Jeremy R Manning
    Princeton Neuroscience Institute, Princeton University, Princeton, New Jersey 08540, USA
    J Neurosci 32:8871-8. 2012
    ..Thus, our work shows that differences in the neural correlates of semantic information, and how they are reactivated before recall, reveal how individuals organize and retrieve memories of words...
  65. doi request reprint Post-ictal hyperfamiliarity syndrome in focal epilepsy
    Krzysztof Bujarski
    Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USA
    Epilepsy Behav 13:567-9. 2008
    ..During this delusion, the step of semantic association was not required to generate the feeling of familiarity, which resulted in every face being labeled as familiar...
  66. ncbi request reprint Lack of association between variations in the brain-derived neurotrophic factor (BDNF) gene and temporal lobe epilepsy
    Falk W Lohoff
    Department of Psychiatry, Center for Neurobiology and Behaviour, University of Pennsylvania School of Medicine, 3535 Market Street, 2nd Floor, R2070, Philadelphia, PA 19104, USA
    Epilepsy Res 66:59-62. 2005
    ..Results suggest that neither of the studied polymorphisms are strong susceptibility factors for TLE in this sample of individuals of European ancestry...
  67. ncbi request reprint Employment outcomes following resective epilepsy surgery
    Peter S Chin
    Robert Wood Johnson Clinical Scholars Program, Department of Medicine, University of California Los Angeles and the Greater Los Angeles VA Health Care System, Los Angeles, California 90095 1769, USA
    Epilepsia 48:2253-7. 2007
    ..Analyze determinates of employment changes from before to 2 years after surgery in refractory focal epilepsy patients...
  68. ncbi request reprint Late seizures in patients initially seizure free after epilepsy surgery
    Theodore H Schwartz
    Neurological Surgery, Weill Cornell Medical College, and New York Presbyterian Hospital, New York, NY 10021, USA
    Epilepsia 47:567-73. 2006
    ..No published reports document the rate and predictors of late recurrence in a large series of patients undergoing surgery in the magnetic resonance imaging (MRI) era...
  69. ncbi request reprint Reduction of AEDs in postsurgical patients who attain remission
    Anne T Berg
    BIOS, NIU, DeKalb, Illinois 60115, USA
    Epilepsia 47:64-71. 2006
    ..Little evidence guides practice regarding the reduction of antiepileptic drugs (AEDs) in individuals who achieve significant periods of remission after resective surgery...
  70. ncbi request reprint Interrater reliability among epilepsy centers: multicenter study of epilepsy surgery
    Sheryl R Haut
    Comprehensive Epilepsy Management Center and Departments of Neurology and Pediatrics of the Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, New York, USA
    Epilepsia 43:1396-401. 2002
    ..To measure the interrater reliability of presurgical testing and surgical decisions among epilepsy centers...
  71. ncbi request reprint Reevaluation of surgery for the treatment of brain metastases: review of 208 patients with single or multiple brain metastases treated at one institution with modern neurosurgical techniques
    Sun Ha Paek
    Department of Neurosurgery, Seoul National University, Seoul, South Korea
    Neurosurgery 56:1021-34; discussion 1021-34. 2005
    ..Patients with brain metastases were analyzed retrospectively to assess the risks and benefits of surgery with modern neurosurgical techniques, including image guidance coupled as indicated with corticography...
  72. ncbi request reprint The multicenter study of epilepsy surgery: recruitment and selection for surgery
    Anne T Berg
    BIOS NIU, DeKalb, Illinois 60115, USA
    Epilepsia 44:1425-33. 2003
    ..Such information is necessary for providing the epidemiologic and clinical context in which epilepsy surgery is currently performed in the United States and in other developed countries...
  73. ncbi request reprint ILAE Commission on the Burden of Epilepsy, Subcommission on the Economic Burden of Epilepsy: Final report 1998-2001
    Charles E Begley
    School of Public Health, University of Texas Houston, Houston, USA
    Epilepsia 43:668-73. 2002
  74. ncbi request reprint Interpatient and intrapatient variability in phenytoin protein binding
    Hoan Linh Banh
    Department of Pharmacy, Queen Elizabeth Health Sciences Center, 1796 Summer Street, NHI 2417, Halifax, Nova Scotia, B3H 3A7 Canada
    Ther Drug Monit 24:379-85. 2002
    ....
  75. ncbi request reprint Ictal asystole and SUDEP
    Norman K So
    Neurology 69:423-4. 2007