S Silberstein

Summary

Affiliation: Thomas Jefferson University
Country: USA

Publications

  1. ncbi request reprint Topiramate in migraine prevention
    Stephen D Silberstein
    Jefferson Headache Center, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
    Headache 45:S57-65. 2005
  2. ncbi request reprint Occipital nerve stimulation for primary headaches
    W B Young
    Department of Neurology, Thomas Jefferson University, Philadelphia, PA, USA
    J Neurosurg Sci 56:307-12. 2012
  3. doi request reprint Efficacy endpoints in migraine clinical trials: the importance of assessing freedom from pain
    S D Silberstein
    Jefferson Headache Center, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Curr Med Res Opin 29:861-7. 2013
  4. doi request reprint Sumatriptan : treatment across the full spectrum of migraine
    Stephen D Silberstein
    Thomas Jefferson University, Jefferson Headache Center, Philadelphia, PA 19107, USA
    Expert Opin Pharmacother 14:1659-67. 2013
  5. doi request reprint OnabotulinumtoxinA for treatment of chronic migraine: PREEMPT 24-week pooled subgroup analysis of patients who had acute headache medication overuse at baseline
    Stephen D Silberstein
    Jefferson Headache Center, Philadelphia, PA 19107, USA
    J Neurol Sci 331:48-56. 2013
  6. doi request reprint Safety and efficacy of peripheral nerve stimulation of the occipital nerves for the management of chronic migraine: results from a randomized, multicenter, double-blinded, controlled study
    Stephen D Silberstein
    Thomas Jefferson University, Philadelphia, PA, USA
    Cephalalgia 32:1165-79. 2012
  7. doi request reprint Randomized, double-blind, placebo-controlled, phase II trial of gabapentin enacarbil for migraine prophylaxis
    Stephen Silberstein
    Jefferson Headache Center, Philadelphia, PA 19107, USA
    Cephalalgia 33:101-11. 2013
  8. doi request reprint Emerging target-based paradigms to prevent and treat migraine
    S D Silberstein
    Jefferson Headache Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Clin Pharmacol Ther 93:78-85. 2013
  9. doi request reprint Trigeminal autonomic cephalalgias other than cluster headache
    Stephen D Silberstein
    Jefferson Headache Center, Philadelphia, PA 19107, USA
    Med Clin North Am 97:321-8. 2013
  10. doi request reprint MAP0004: dihydroergotamine mesylate inhalation aerosol for acute treatment of migraine
    Stephen Silberstein
    Thomas Jefferson University, Jefferson Headache Center, Philadelphia, PA 19107, USA
    Expert Opin Pharmacother 13:1961-8. 2012

Detail Information

Publications91

  1. ncbi request reprint Topiramate in migraine prevention
    Stephen D Silberstein
    Jefferson Headache Center, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
    Headache 45:S57-65. 2005
    ..Topiramate is a first-line migraine preventive drug and should especially be considered as a preferred treatment for all patients who are concerned about gaining weight, who are currently overweight, or who have coexisting epilepsy...
  2. ncbi request reprint Occipital nerve stimulation for primary headaches
    W B Young
    Department of Neurology, Thomas Jefferson University, Philadelphia, PA, USA
    J Neurosurg Sci 56:307-12. 2012
    ..A few case reports suggest a possible benefit in short-lasting unilateral neuralgiform headache attacks with conjunctival injection tearing and short-lasting unilateral neuralgiform headache...
  3. doi request reprint Efficacy endpoints in migraine clinical trials: the importance of assessing freedom from pain
    S D Silberstein
    Jefferson Headache Center, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Curr Med Res Opin 29:861-7. 2013
    ..The measures of pain-free response 2 hours postdose and sustained pain-free response can differentiate among treatments and be used to guide therapeutic choices...
  4. doi request reprint Sumatriptan : treatment across the full spectrum of migraine
    Stephen D Silberstein
    Thomas Jefferson University, Jefferson Headache Center, Philadelphia, PA 19107, USA
    Expert Opin Pharmacother 14:1659-67. 2013
    ..Triptans are the first-line treatment for moderate-to-severe migraine headaches. Sumatriptan , the first triptan, is available in different formulations, including subcutaneous (SQ), intranasal, transdermal, oral, and suppository options...
  5. doi request reprint OnabotulinumtoxinA for treatment of chronic migraine: PREEMPT 24-week pooled subgroup analysis of patients who had acute headache medication overuse at baseline
    Stephen D Silberstein
    Jefferson Headache Center, Philadelphia, PA 19107, USA
    J Neurol Sci 331:48-56. 2013
    ..210) between groups, except for triptan intakes (p<0.001), where the onabotulinumtoxinA-treated group was favored. OnabotulinumtoxinA was effective and well tolerated as headache prophylaxis in CM+MO patients...
  6. doi request reprint Safety and efficacy of peripheral nerve stimulation of the occipital nerves for the management of chronic migraine: results from a randomized, multicenter, double-blinded, controlled study
    Stephen D Silberstein
    Thomas Jefferson University, Philadelphia, PA, USA
    Cephalalgia 32:1165-79. 2012
    ..Chronic migraine (CM) is a debilitating neurological disorder with few treatment options. Peripheral nerve stimulation (PNS) of the occipital nerves is a potentially promising therapy for CM patients...
  7. doi request reprint Randomized, double-blind, placebo-controlled, phase II trial of gabapentin enacarbil for migraine prophylaxis
    Stephen Silberstein
    Jefferson Headache Center, Philadelphia, PA 19107, USA
    Cephalalgia 33:101-11. 2013
    ..The objective of this article is to evaluate the efficacy and safety of gabapentin enacarbil (GEn) for migraine prophylaxis...
  8. doi request reprint Emerging target-based paradigms to prevent and treat migraine
    S D Silberstein
    Jefferson Headache Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Clin Pharmacol Ther 93:78-85. 2013
    ..A recent development is the creation of antibodies to CGRP and its receptor for migraine prevention...
  9. doi request reprint Trigeminal autonomic cephalalgias other than cluster headache
    Stephen D Silberstein
    Jefferson Headache Center, Philadelphia, PA 19107, USA
    Med Clin North Am 97:321-8. 2013
    ..SUNCT is a subtype of SUNA in which both conjunctival injection and tearing are present. SUNA differs from SUNCT in that autonomic symptoms are less prominent...
  10. doi request reprint MAP0004: dihydroergotamine mesylate inhalation aerosol for acute treatment of migraine
    Stephen Silberstein
    Thomas Jefferson University, Jefferson Headache Center, Philadelphia, PA 19107, USA
    Expert Opin Pharmacother 13:1961-8. 2012
    ..MAP0004 was developed to provide the anti-migraine efficacy of DHE, with fewer systemic effects than intravenous dosing...
  11. pmc Headaches in pregnancy
    Stephen D Silberstein
    Jefferson Headache Center, 111 South Eleventh Street, Gibbon Building, Suite 8130, Philadelphia, PA 19107, USA
    J Headache Pain 6:172-4. 2005
    ..Nonpharmacologic treatment is the ideal solution; however, analgesics such as acetaminophen and opioids can be used on a limited basis. Preventive therapy is a last resort...
  12. ncbi request reprint Botulinum toxin type A for the prophylactic treatment of chronic daily headache: a randomized, double-blind, placebo-controlled trial
    Stephen D Silberstein
    Jefferson Headache Center, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Mayo Clin Proc 80:1126-37. 2005
    ..To identify a treatment-responsive population for botulinum toxin type A (BoNTA) and to evaluate the safety and efficacy of 3 different doses of BoNTA as prophylactic treatment of chronic daily headache (CDH)...
  13. ncbi request reprint Chronic daily headache
    Stephen D Silberstein
    Jefferson Headache Center, Thomas Jefferson University Hospital, 111 S 11th Street, Gibbon Bldg, Suite 8130, Philadelphia, PA 19107 4824, USA
    J Am Osteopath Assoc 105:23S-29S. 2005
    ..This article reviews the criteria for medication-overuse headache and the subset of headaches making up chronic daily headache, as well as the epidemiologic and therapeutic aspects of these disorders...
  14. ncbi request reprint Preventive treatment of headaches
    Stephen D Silberstein
    Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
    Curr Opin Neurol 18:289-92. 2005
    ..To review recent advances in preventive headache treatment...
  15. ncbi request reprint Topiramate monotherapy in epilepsy and migraine prevention
    Stephen D Silberstein
    Thomas Jefferson University, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107, USA
    Clin Ther 27:154-65. 2005
    ....
  16. ncbi request reprint Topiramate in migraine prevention: evidence-based medicine from clinical trials
    S D Silberstein
    Department of Neurology, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
    Neurol Sci 25:S244-5. 2004
    ..Therefore, topiramate has demonstrated safety and represents an effective option in the prevention of migraine, as supported by extensive clinical research...
  17. ncbi request reprint Headaches in pregnancy
    Stephen D Silberstein
    Jefferson Medical College, Thomas Jefferson University Hospital, Philadelphia, PA, USA
    Neurol Clin 22:727-56. 2004
    ..Nonpharmacologic treatment is the ideal solution; however, analgesics, such as acetaminophen and narcotics, can be used ona limited basis. Preventive therapy is a last resort...
  18. ncbi request reprint Preventive treatment of migraine
    Stephen D Silberstein
    Jefferson Headache Center, 111 South 11th Street, Suite 8130, Philadelphia, PA 19107, USA
    Trends Pharmacol Sci 27:410-5. 2006
    ..In this article, I review evidence of the effectiveness of migraine preventive drugs. I also discuss the setting of treatment priorities...
  19. ncbi request reprint Efficacy and tolerability of topiramate 200 mg/d in the prevention of migraine with/without aura in adults: a randomized, placebo-controlled, double-blind, 12-week pilot study
    Stephen D Silberstein
    Jefferson Headache Center, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
    Clin Ther 28:1002-11. 2006
    ..Several large, randomized, double-blind, placebo-controlled trials have found topiramate (TPM) to be effective and generally well tolerated as a preventive therapy for migraine...
  20. ncbi request reprint Menstrually related migraine: breaking the cycle in your clinical practice
    Stephen D Silberstein
    Department of Neurology, Jefferson Headache Center, Division of General Obstetrics and Gynecology and Jefferson Fibroid Center, Jefferson Medical College, Philadelphia, Pennsylvania, USA
    J Reprod Med 52:888-95. 2007
    ..Acute and shortterm preventive therapy with triptans is effective; oral contraceptives may be used for long-term preventive therapy...
  21. doi request reprint Oxcarbazepine in migraine headache: a double-blind, randomized, placebo-controlled study
    S Silberstein
    Jefferson Headache Center, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
    Neurology 70:548-55. 2008
    ..To evaluate the efficacy, safety, and tolerability of oxcarbazepine (1,200 mg/day) vs placebo as prophylactic therapy for patients with migraine headaches...
  22. doi request reprint Guidelines for controlled trials of prophylactic treatment of chronic migraine in adults
    S Silberstein
    Jefferson Headache Center, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA corrected
    Cephalalgia 28:484-95. 2008
    ..These Guidelines are intended to assist in the design of well-controlled clinical trials of chronic migraine in adults, and do not apply to studies in children or adolescents...
  23. doi request reprint Multimechanistic (sumatriptan-naproxen) early intervention for the acute treatment of migraine
    S D Silberstein
    Jefferson Headache Center, 111 South 11th Street, Suite 8130, Philadelphia, PA 19107, USA
    Neurology 71:114-21. 2008
    ..Research suggests treating a migraine at the first sign of pain increases the likelihood of the best clinical outcome...
  24. doi request reprint Treatment recommendations for migraine
    Stephen D Silberstein
    Jefferson Headache Center, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Nat Clin Pract Neurol 4:482-9. 2008
    ..Preventive treatments are selected on the basis of the drugs' side-effect profiles and the patient's coexistent and comorbid conditions...
  25. doi request reprint Preventive migraine treatment
    Stephen D Silberstein
    Department of Neurology, Jefferson Headache Center, Thomas Jefferson University Hospital, 111 South Eleventh Street, Gibbon Building, Suite 8130, Philadelphia, PA 19107, USA
    Neurol Clin 27:429-43. 2009
    ..Drug therapy may be beneficial for both disorders; however, it is also a potential confounder of optimal treatment of either...
  26. doi request reprint Tonabersat, a gap-junction modulator: efficacy and safety in two randomized, placebo-controlled, dose-ranging studies of acute migraine
    S D Silberstein
    Jefferson Headache Center, Philadelphia, PA 19107, USA
    Cephalalgia 29:17-27. 2009
    ..Based on the pharmacokinetics and actions on cortical spreading depression, tonabersat may have potential value in migraine prophylaxis...
  27. doi request reprint Tonabersat, a novel gap-junction modulator for the prevention of migraine
    S D Silberstein
    Jefferson Headache Center, Philadelphia, PA 19107, USA
    Cephalalgia 29:28-35. 2009
    ..In preclinical and clinical trials, tonabersat was well tolerated, with no cardiovascular effects; the pharmacokinetic profile suggested its usefulness in the prophylaxis of migraine...
  28. ncbi request reprint A randomized trial of frovatriptan for the intermittent prevention of menstrual migraine
    Stephen D Silberstein
    Thomas Jefferson University, Philadelphia, PA, USA
    Neurology 63:261-9. 2004
    ..It has a long half-life and good tolerability. These characteristics suggest that frovatriptan may be useful for the intermittent prevention of MAM...
  29. ncbi request reprint Topiramate in migraine prevention: results of a large controlled trial
    Stephen D Silberstein
    Jefferson Headache Center, Thomas Jefferson University Hospital, Philadelphia, PA19107, USA
    Arch Neurol 61:490-5. 2004
    ..Open-label trials and small controlled studies report topiramate's efficacy in migraine prevention...
  30. ncbi request reprint Migraine
    Stephen D Silberstein
    Jefferson Headache Centre, Thomas Jefferson University Hospital, Philadelphia, PA, USA
    Lancet 363:381-91. 2004
    ..Preventive treatment decreases migraine frequency and improves quality of life. More treatments are being developed, which provides hope to the many patients whose migraines remain uncontrolled...
  31. ncbi request reprint Headaches due to nasal and paranasal sinus disease
    Stephen D Silberstein
    Thomas Jefferson University Hospital, Jefferson Headache Center, 111 South Eleventh Street, Suite 8130, Philadelphia, PA 19107, USA
    Neurol Clin 22:1-19, v. 2004
    ..Whether or not nasal obstruction can lead to chronic headache is controversial. Paradoxically, sinus disease also tends to be underdiagnosed, as sphenoid sinus infection frequently is missed...
  32. doi request reprint Meeting acute migraine treatment needs through novel treatment formulations
    Stephen D Silberstein
    Jefferson Headache Center, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107, USA
    Neurotherapeutics 7:153-8. 2010
    ..Orally inhaled dihydroergotamine is a new treatment modality. These novel formulations may help patients achieve desirable outcomes, including faster and more complete relief, more consistent response, and improved drug tolerability...
  33. ncbi request reprint Randomized, placebo-controlled trial of rofecoxib in the acute treatment of migraine
    S Silberstein
    Jefferson Headache Center, Philadelphia, PA 19107, USA
    Neurology 62:1552-7. 2004
    ..To investigate the clinical profile of rofecoxib, a long-acting (approximately 17-hour half-life) selective cyclo-oxygenase-2 inhibitor, for the acute treatment of migraine...
  34. doi request reprint Scheduled short-term prevention with frovatriptan for migraine occurring exclusively in association with menstruation
    Stephen D Silberstein
    Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
    Headache 49:1283-97. 2009
    ....
  35. ncbi request reprint Efficacy and safety of acetaminophen, aspirin, and caffeine in alleviating migraine headache pain: three double-blind, randomized, placebo-controlled trials
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Montefiore Headache Unit, Bronx, NY 10467, USA
    Arch Neurol 55:210-7. 1998
    ..To assess the effectiveness of the nonprescription combination of acetaminophen, aspirin, and caffeine in alleviating migraine headache pain...
  36. ncbi request reprint Botulinum toxin type A as a migraine preventive treatment. For the BOTOX Migraine Clinical Research Group
    S Silberstein
    Thomas Jefferson University School of Medicine, Philadelphia, PA, USA
    Headache 40:445-50. 2000
    ..CONCLUSIONS: Pericranial injection of botulinum toxin type A, 25 U, was found to be a safe treatment that significantly reduced migraine frequency, migraine severity, acute medication usage, and associated vomiting...
  37. ncbi request reprint The evolving management of migraine
    Avi Ashkenazi
    Jefferson Headache Center, Department of Neurology, Thomas Jefferson University Hospital, Gibbon Building, Suite 8130, 111 South Eleventh Street, Philadelphia, PA 19107, USA
    Curr Opin Neurol 16:341-5. 2003
    ..To review recent advances in acute and preventive migraine treatment...
  38. ncbi request reprint Hormone-related headache: pathophysiology and treatment
    Avi Ashkenazi
    Department of Neurology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA
    CNS Drugs 20:125-41. 2006
    ..Migraine is not a risk factor for stroke in postmenopausal women. When considering symptomatic HRT for postmenopausal migraneurs, the usual indications and contraindications should be applied. HRT may also exacerbate migraine...
  39. doi request reprint Triptans: actions and reactions
    Stephanie J Nahas
    Thomas Jefferson University Hospital Neurology, Philadelphia, PA 19107 5092, USA
    Headache 48:611-3. 2008
    ..Some commonly reported adverse events are paresthesias, tingling, and transient worsening of headache. Why do patients develop these symptoms? Our unique case may shed light on its actions...
  40. ncbi request reprint Anticonvulsants in migraine
    William B Young
    Department of Neurology, Thomas Jefferson University Hospital, Jefferson Headache Center, 111 South 11th Street, Gibbon Building, Suite 8130, Philadelphia, PA 19107, USA
    Curr Pain Headache Rep 8:244-50. 2004
    ..Lamotrigine may be effective at controlling migraine aura, but has not demonstrated effectiveness at controlling migraine headache. Anticonvulsants are a useful option for the preventive treatment of migraine...
  41. ncbi request reprint Impact of topiramate migraine prophylaxis on workplace productivity: results from two US randomized, double-blind, placebo-controlled, multicenter trials
    Jennifer H Lofland
    Department of Health Policy Drs Lofland, Gagne, and Pizzi, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA
    J Occup Environ Med 49:252-7. 2007
    ..We conducted this study to determine whether topiramate at 100 mg/d for the treatment of migraine headache is associated with improved productivity in the workplace...
  42. ncbi request reprint Probable migraine in the United States: results of the American Migraine Prevalence and Prevention (AMPP) study
    S Silberstein
    Jefferson Headache Center, Philadelphia, PA, USA
    Cephalalgia 27:220-34. 2007
    ..In contrast to migraine, which is less prevalent in African-Americans than in Whites, PM is more prevalent in African-Americans than in Whites. In the USA, many with PM do not receive adequate treatment...
  43. ncbi request reprint Dihydroergotamine for early and late treatment of migraine with cutaneous allodynia: an open-label pilot trial
    Stephen D Silberstein
    Jefferson Headache Center, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Headache 47:878-85. 2007
    ..To explore whether dihydroergotamine (D.H.E. 45) is equally effective and safe for migraine with allodynia, when administered either early or late in an attack...
  44. ncbi request reprint Efficacy and safety of topiramate for the treatment of chronic migraine: a randomized, double-blind, placebo-controlled trial
    Stephen D Silberstein
    Jefferson Headache Center, Philadelphia, PA 19107, USA
    Headache 47:170-80. 2007
    ..To evaluate the efficacy and safety of topiramate (100 mg/day) compared with placebo for the treatment of chronic migraine...
  45. ncbi request reprint Efficacy of eletriptan in migraine-related functional impairment: functional and work productivity outcomes
    Stephen D Silberstein
    Jefferson Headache Center, Philadelphia, PA 19107, USA
    Headache 47:673-82. 2007
    ....
  46. ncbi request reprint Botulinum neurotoxin for the treatment of migraine and other primary headache disorders
    Andrew M Blumenfeld
    Department of Neurology, Kaiser Permanente, 4405 Vandever Avenue, San Diego, CA 92120, USA
    Dermatol Clin 22:167-75. 2004
    ..Educating patients and addressing headache triggers and optimizing acute treatment improve the outcome of any preventive program...
  47. doi request reprint Diagnosis and treatment of the menstrual migraine patient
    Stephen D Silberstein
    Thomas Jefferson University, Philadelphia, PA, USA
    Headache 48:S115-23. 2008
    ..Herein we review the difference between non-menstrual migraine, PMM, and MRM and identify effective treatment strategies for appropriate management of migraine associated with hormonal fluctuations...
  48. ncbi request reprint Botulinum neurotoxin for the treatment of migraine and other primary headache disorders
    David Dodick
    Department of Neurology, Mayo Clinic, Scottsdale, AZ 85259, USA
    Clin Dermatol 22:76-81. 2004
    ..These studies may provide further evidence that BoNT/A is an effective option for the preventive treatment of migraine...
  49. ncbi request reprint Botulinum toxin type a for the prophylaxis of chronic daily headache: subgroup analysis of patients not receiving other prophylactic medications: a randomized double-blind, placebo-controlled study
    David W Dodick
    Department of Neurology, Mayo Clinic, Scottsdale, AZ 85259, USA
    Headache 45:315-24. 2005
    ..Irvine, CA) for the prophylaxis of headaches in patients with chronic daily headache (CDH) without the confounding factor of concurrent prophylactic medications...
  50. pmc Improved identification of allodynic migraine patients using a questionnaire
    A Ashkenazi
    Department of Neurology, Thomas Jefferson University Hospital, Jefferson Headache Center, Philadelphia, PA, USA
    Cephalalgia 27:325-9. 2007
    ....
  51. doi request reprint OnabotulinumtoxinA for treatment of chronic migraine: pooled results from the double-blind, randomized, placebo-controlled phases of the PREEMPT clinical program
    David W Dodick
    Department of Neurology, Mayo Clinic Arizona, Phoenix, AZ, USA
    Headache 50:921-36. 2010
    ..To assess the efficacy, safety, and tolerability of onabotulinumtoxinA (BOTOX) as headache prophylaxis in adults with chronic migraine...
  52. ncbi request reprint Therapeutic options in the management of headache attributed to rhinosinusitis
    Madhavi Gupta
    Thomas Jefferson University, Jefferson Headache Center, Gibbon Building, Suite 8130, 111 South Eleventh Street, Philadelphia, Pennsylvania 19107, USA
    Expert Opin Pharmacother 6:715-22. 2005
    ..This is an important distinction and the treatment is very different. This review covers the most recent definitions, epidemiology, pathophysiology, diagnostics and treatment of ABRS and the resulting headache as defined by the IHS...
  53. ncbi request reprint The impact of migraine on daily activities: effect of topiramate compared with placebo
    Stephen D Silberstein
    Jefferson Headache Center, Philadelphia, PA 19107, USA
    Curr Med Res Opin 22:1021-9. 2006
    ....
  54. ncbi request reprint Diagnostic testing for chronic daily headache
    Randolph W Evans
    Jefferson Headache Clinic, Philadelphia, PA 19107 4824, USA
    Headache 42:556-9. 2002
  55. ncbi request reprint Migraine preventive medication reduces resource utilization
    Stephen D Silberstein
    Department of Neurology, Jefferson Headache Center, Thomas Jefferson College of Medicine, Philadelphia, PA 19107, USA
    Headache 43:171-8. 2003
    ..To determine if long-term resource utilization is reduced by adding a preventive medication to a migraine management regimen that already includes acute medication...
  56. ncbi request reprint Pharmacological profile and clinical characteristics of frovatriptan in the acute treatment of migraine: introduction
    Stephen D Silberstein
    Jefferson Headache Center, Philadelphia, PA 19107, USA
    Headache 42:S45-6. 2002
  57. ncbi request reprint How to pick optimal acute treatment for migraine headache
    M Sanchez del Rio
    Jefferson Headache Center, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
    Curr Pain Headache Rep 5:170-8. 2001
    ..This will aid in successful headache management, by increasing compliance and decreasing disability and cost...
  58. ncbi request reprint Intravenous propofol in the treatment of refractory headache
    Paula M Mendes
    Thomas Jefferson University Hospital, Jefferson Headache Center, Philadelphia, Pennsylvania 19107, USA
    Headache 42:638-41. 2002
    ..There were no complications. Intravenous propofol is safe and effective when used under monitored conditions and should be considered for patients who have refractory chronic daily headache and have failed other interventions...
  59. doi request reprint Headache prophylaxis with BoNTA: patient characteristics
    Stephen D Silberstein
    Jefferson Headache Center, Thomas Jefferson University Hospital, Philadelphia, PA, USA
    Headache 50:63-70. 2010
    ..To assess the characteristics of patients receiving botulinum toxin type A (BoNTA; BOTOX((R))) in the treatment of headache (HA) disorders...
  60. ncbi request reprint Further evaluation of rizatriptan in menstrual migraine: retrospective analysis of long-term data
    Stephen D Silberstein
    Jefferson Headache Center, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA
    Headache 42:917-23. 2002
    ..To determine the long-term efficacy of oral rizatriptan 10-mg wafers in the treatment of menstrual migraine attacks...
  61. ncbi request reprint The headache of SAH responds to sumatriptan
    Jay H Rosenberg
    UCSD School of Medicine, La Jolla, CA and Jefferson Headache Center, Philadelphia, PA 19107, USA
    Headache 45:597-8. 2005
    ..The failure to respond in the reported cases of meningitis may be due to sensitization...
  62. ncbi request reprint Botulinum toxin and other new approaches to migraine therapy
    Avi Ashkenazi
    Jefferson Headache Center, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107, USA
    Annu Rev Med 55:505-18. 2004
    ..Another new approach to migraine prevention is angiotensin type 1 (AT1) receptor blockade. The high tolerability of the AT1 receptor blocker candesartan warrants further studies to assess its role in migraine prevention...
  63. ncbi request reprint Chronic migraine: diagnosis and management strategy
    Stephen D Silberstein
    Department of Neurology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA
    Rev Neurol Dis 1:155-60. 2004
    ..Management strategies are presented and the revised IHS criteria are discussed...
  64. ncbi request reprint Acute migraine treatment: patterns of use and satisfaction in a clinical population
    Shahram N Malik
    Thomas Jefferson University, Jefferson Headache Center, Philadelphia, PA 19107, USA
    Headache 46:773-80. 2006
    ..The sequence and timing of taking migraine medications, whether prescription or over-the-counter, and the patient's response to their treatment, is unknown...
  65. ncbi request reprint Olanzapine in the treatment of refractory migraine and chronic daily headache
    Stephen D Silberstein
    Jefferson Headache Center, Department of Neurology, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
    Headache 42:515-8. 2002
    ..We thus decided to assess the value of olanzapine in the treatment of chronic refractory headache...
  66. ncbi request reprint Tramadol/acetaminophen for the treatment of acute migraine pain: findings of a randomized, placebo-controlled trial
    Stephen D Silberstein
    Jefferson Medical College, Philadelphia, PA, USA
    Headache 45:1317-27. 2005
    ..To compare tramadol/acetaminophen (APAP) and placebo for the management of acute migraine pain...
  67. ncbi request reprint Topiramate in migraine prophylaxis: long-term impact on resource utilization and cost
    Stephen D Silberstein
    Department of Neurology, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Headache 47:500-10. 2007
    ..Background.-Preventive migraine therapy with TPM significantly reduces the frequency of migraine attacks. Limited data exist on the real-world health care consumption associated with TPM therapy for migraine prevention...
  68. ncbi request reprint Hemicrania continua
    Stephen D Silberstein
    Thomas Jefferson University Hospital, Jefferson Headache Center, Gibbon Bldg, Suite 8130, 111 S 11th St, Philadelphia, PA 19107, USA
    Arch Neurol 59:1029-30. 2002
  69. doi request reprint Single-pulse transcranial magnetic stimulation for acute treatment of migraine with aura: a randomised, double-blind, parallel-group, sham-controlled trial
    Richard B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Lancet Neurol 9:373-80. 2010
    ..We aimed to assess the efficacy and safety of a new portable sTMS device for acute treatment of migraine with aura...
  70. doi request reprint Intravenous lidocaine infusion for the treatment of post-acoustic neuroma resection headache: a case report
    Daniel Schere
    Thomas Jefferson University Hospital, Jefferson Headache Center, Philadelphia, PA 19107 2060, USA
    Headache 49:302-3. 2009
    ..Presentation of a case report of a 47-year-old male with a post-acoustic neuroma resection intractable headache responding to intravenous lidocaine infusion. The patient was then switched to mexiletine, with good response...
  71. ncbi request reprint Ergotamine and dihydroergotamine: history, pharmacology, and efficacy
    Stephen D Silberstein
    Department of Neurology, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
    Headache 43:144-66. 2003
    ..The scientific evidence for efficacy is stronger for dihydroergotamine than for ergotamine. Their wide use is based on long-term experience...
  72. ncbi request reprint Removing barriers to appropriate migraine treatment: formulary limitations and triptan package size
    Stephen D Silberstein
    Jefferson Headache Center, Philadelphia, PA 19107, USA
    Headache 45:1250-4. 2005
    ....
  73. ncbi request reprint Headache management for the pain specialist
    Avi Ashkenazi
    Jefferson Headache Center, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
    Reg Anesth Pain Med 29:462-75. 2004
    ..Cervicogenic headache is common and needs to be diagnosed correctly since it may require specific therapy. Nerve blocks are useful for some patients with primary, as well as secondary, headaches...
  74. ncbi request reprint Hemicrania continua-like headache associated with internal carotid artery dissection may respond to indomethacin
    Avi Ashkenazi
    Department of Neurology, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
    Headache 47:127-30. 2007
    ..Patients with a clinical picture similar to HC should be managed with a high index of suspicion for a possible cervical arterial dissection...
  75. ncbi request reprint Pharmacological approaches to managing migraine and associated comorbidities--clinical considerations for monotherapy versus polytherapy
    Stephen D Silberstein
    Thomas Jefferson University, Philadelphia, PA 19107, USA
    Headache 47:585-99. 2007
    ....
  76. ncbi request reprint Less is not more: underutilization of headache medications in a university hospital emergency department
    Madhavi X Gupta
    Jefferson Headache Center, Department of Neurology, Thomas Jefferson University, Philadelphia, PA 19013, USA
    Headache 47:1125-33. 2007
    ..To gain knowledge of episodic headache patients who seek care at an urban university emergency department (ED), to evaluate the care they receive and to examine the impact of the ED on these headache patients...
  77. ncbi request reprint Neurotoxins in the neurobiology of pain
    Stephen D Silberstein
    Jefferson Headache Center, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
    Headache 43:S2-8. 2003
    ..This review describes in detail the neurobiological mechanisms and pathways for pain sensation, with a focus on migraine pain...
  78. pmc Migraine in pregnancy
    Peter J Goadsby
    Headache Group, Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    BMJ 336:1502-4. 2008
  79. ncbi request reprint Combination therapy in acute migraine treatment: the rationale behind the current treatment options
    Stephen D Silberstein
    Postgrad Med . 2006
    ..The rationale for using combination therapy will first be discussed within the context of clinical conditions in which it is already the standard of care. This will be followed by a discussion of the rationale for use in migraine...
  80. ncbi request reprint Efficacy and tolerability of oral zolmitriptan in menstrually associated migraine: a randomized, prospective, parallel-group, double-blind, placebo-controlled study
    Elizabeth Loder
    Spaulding Rehabilitation Hospital, Boston, Mass 02114, USA
    Headache 44:120-30. 2004
    ..Approximately 60% of female migraineurs report experiencing migraine in association with menstruation, while 7% to 25% experience attacks almost exclusively with menstruation...
  81. ncbi request reprint Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial
    Jerome Goldstein
    San Francisco Headache Clinic, San Francisco Clinical Research Center, CA 94109, USA
    Headache 45:973-82. 2005
    ..To address the need for a rigorous, direct comparison of prescription and over-the-counter (OTC) migraine drugs and to expand the database on early treatment of migraine...
  82. ncbi request reprint Productivity cost benefit to employers of treating migraine with rizatriptan: a specific worksite analysis and model
    William C Gerth
    Worldwide Outcomes Research, Merck and Co, Inc, Whitehouse Station, New Jersey 08889, USA
    J Occup Environ Med 46:48-54. 2004
    ..S. company. There is a substantial productivity cost burden of migraine from a U.S. employer perspective. These productivity costs can be reduced significantly by treating migraine headaches with rizatriptan...
  83. ncbi request reprint Acetaminophen, aspirin, and caffeine in combination versus ibuprofen for acute migraine: results from a multicenter, double-blind, randomized, parallel-group, single-dose, placebo-controlled study
    Jerome Goldstein
    San Francisco Headache Clinic, CA 94109, USA
    Headache 46:444-53. 2006
    ..Compare the effectiveness of a combination analgesic containing acetaminophen, aspirin, and caffeine to that of ibuprofen in the treatment of migraine...
  84. ncbi request reprint Hemicrania continua responds to cyclooxygenase-2 inhibitors
    Mario F P Peres
    Jefferson Headache Center, Department of Neurology, Thomas Jefferson University Hospital, Philadelphia, PA, USA
    Headache 42:530-1. 2002
    ..We report the treatment response to two cyclooxygenase-2 inhibitors, celecoxib and rofecoxib, in a series of patients with hemicrania continua...
  85. ncbi request reprint Analyses of cost-effectiveness of migraine therapies should consider multiple measures
    Stephen D Silberstein
    J Manag Care Pharm 9:279-80; author reply 280-1. 2003
  86. ncbi request reprint Control of topiramate-induced paresthesias with supplemental potassium
    Stephen D Silberstein
    Headache 42:85. 2002
  87. ncbi request reprint Tricyclic antidepressant medication, stress management therapy, and their combination in the management of chronic tension-type headache
    Stephen D Silberstein
    Curr Neurol Neurosci Rep 2:105-7. 2002
  88. ncbi request reprint Procedures for administering botulinum toxin type A for migraine and tension-type headache
    Andrew M Blumenfeld
    San Diego, Calif 92130, USA
    Headache 43:884-91. 2003
  89. ncbi request reprint Botulinum toxin type A: myths, facts, and current research
    Stephen D Silberstein
    Headache 43:S1. 2003
  90. ncbi request reprint Painkiller headache
    Stephen D Silberstein
    Neurology 59:972-4. 2002