Andrew B Newberg

Summary

Affiliation: Thomas Jefferson University
Country: USA

Publications

  1. pmc Multi-nutrient supplement improves hormone ratio associated with cancer risk
    Anthony J Bazzan
    Myrna Brind Center of Integrative Medicine, Thomas Jefferson University, 925 Chestnut Street, Suite 120, Philadelphia, PA 19107, USA
    J Transl Med 11:252. 2013
  2. pmc Low brain serotonin transporter binding in major depressive disorder
    Andrew B Newberg
    Myrna Brind Center of Integrative Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Psychiatry Res 202:161-7. 2012
  3. doi request reprint Initial clinical comparison of 18F-florbetapir and 18F-FDG PET in patients with Alzheimer disease and controls
    Andrew B Newberg
    Thomas Jefferson University and Hospital, Philadelphia, Pennsylvania 19107, USA
    J Nucl Med 53:902-7. 2012
  4. doi request reprint Positron emission tomography in psychiatric disorders
    Andrew B Newberg
    Department of Emergency Medicine and Radiology, Thomas Jefferson University, 1015 Chestnut Street, Suite 412, Philadelphia, PA 19107, USA
    Ann N Y Acad Sci 1228:E13-25. 2011
  5. ncbi request reprint 123I-ADAM binding to serotonin transporters in patients with major depression and healthy controls: a preliminary study
    Andrew B Newberg
    Division of Nuclear Medicine, Department of Radiology, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA
    J Nucl Med 46:973-7. 2005
  6. ncbi request reprint Differences in [99mTc]TRODAT-1 SPECT binding to dopamine transporters in patients with multiple system atrophy and Parkinson's disease
    Randel L Swanson
    Division of Nuclear Medicine, 110 Donner Building, H U P, 3400 Spruce Street, Philadelphia, PA, 19104, USA
    Eur J Nucl Med Mol Imaging 32:302-7. 2005
  7. ncbi request reprint Meditation and neurodegenerative diseases
    Andrew B Newberg
    Jefferson Myrna Brind Center of Integrative Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania
    Ann N Y Acad Sci 1307:112-23. 2014
  8. pmc Greater striatal dopamine transporter density may be associated with major depressive episode
    Jay D Amsterdam
    Depression Research Unit, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    J Affect Disord 141:425-31. 2012
  9. doi request reprint Feasibility of estimation of brain volume and 2-deoxy-2-(18)F-fluoro-D-glucose metabolism using a novel automated image analysis method: application in Alzheimer's disease
    Erik S Musiek
    Department of Neurology, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104, USA
    Hell J Nucl Med 15:190-6. 2012
  10. doi request reprint Changes in cerebral blood flow and anxiety associated with an 8-week mindfulness programme in women with breast cancer
    Daniel A Monti
    Jefferson Myrna Brind Center of Integrative Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Stress Health 28:397-407. 2012

Research Grants

Collaborators

Detail Information

Publications43

  1. pmc Multi-nutrient supplement improves hormone ratio associated with cancer risk
    Anthony J Bazzan
    Myrna Brind Center of Integrative Medicine, Thomas Jefferson University, 925 Chestnut Street, Suite 120, Philadelphia, PA 19107, USA
    J Transl Med 11:252. 2013
    ..The present study was designed to evaluate if a multi-nutrient supplement containing targeted botanical constituents would affect the 2-HE/16 alpha-HE ratio in middle-aged women...
  2. pmc Low brain serotonin transporter binding in major depressive disorder
    Andrew B Newberg
    Myrna Brind Center of Integrative Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Psychiatry Res 202:161-7. 2012
    ..These findings confirm prior observations of lower SERT binding in depression, and suggest that low SERT binding may represent a putative biomarker of depression. Future studies are needed to confirm these observations...
  3. doi request reprint Initial clinical comparison of 18F-florbetapir and 18F-FDG PET in patients with Alzheimer disease and controls
    Andrew B Newberg
    Thomas Jefferson University and Hospital, Philadelphia, Pennsylvania 19107, USA
    J Nucl Med 53:902-7. 2012
    ..The purpose of this study was to determine how clinical interpretations of the (18)F-amyloid tracer florbetapir compares diagnostically with (18)F-FDG PET when evaluating patients with Alzheimer disease (AD) and controls...
  4. doi request reprint Positron emission tomography in psychiatric disorders
    Andrew B Newberg
    Department of Emergency Medicine and Radiology, Thomas Jefferson University, 1015 Chestnut Street, Suite 412, Philadelphia, PA 19107, USA
    Ann N Y Acad Sci 1228:E13-25. 2011
    ....
  5. ncbi request reprint 123I-ADAM binding to serotonin transporters in patients with major depression and healthy controls: a preliminary study
    Andrew B Newberg
    Division of Nuclear Medicine, Department of Radiology, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA
    J Nucl Med 46:973-7. 2005
    ..We hypothesized that SERT binding activity may be altered in patients with MDD. This study compared SERT binding in patients with MDD with that in healthy controls...
  6. ncbi request reprint Differences in [99mTc]TRODAT-1 SPECT binding to dopamine transporters in patients with multiple system atrophy and Parkinson's disease
    Randel L Swanson
    Division of Nuclear Medicine, 110 Donner Building, H U P, 3400 Spruce Street, Philadelphia, PA, 19104, USA
    Eur J Nucl Med Mol Imaging 32:302-7. 2005
    ..This study evaluated whether [99mTc]TRODAT-1 binding to the dopamine transporter differentiates MSA from other movement disorders...
  7. ncbi request reprint Meditation and neurodegenerative diseases
    Andrew B Newberg
    Jefferson Myrna Brind Center of Integrative Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania
    Ann N Y Acad Sci 1307:112-23. 2014
    ..This review discusses the current data on meditation, memory, and attention, and the potential applications of meditation techniques in patients with neurodegenerative diseases. ..
  8. pmc Greater striatal dopamine transporter density may be associated with major depressive episode
    Jay D Amsterdam
    Depression Research Unit, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    J Affect Disord 141:425-31. 2012
    ..We hypothesized that striatal DVR values would be greater in depressed versus non-depressed subjects, and that greater DVR values may represent a possible clinical biomarker of depression...
  9. doi request reprint Feasibility of estimation of brain volume and 2-deoxy-2-(18)F-fluoro-D-glucose metabolism using a novel automated image analysis method: application in Alzheimer's disease
    Erik S Musiek
    Department of Neurology, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104, USA
    Hell J Nucl Med 15:190-6. 2012
    ..In conclusion, our findings suggest that ROVER may serve as a useful quantitative adjunct to visual or regional assessment and aid analysis of whole-brain metabolism in AD and other neurologic and psychiatric diseases...
  10. doi request reprint Changes in cerebral blood flow and anxiety associated with an 8-week mindfulness programme in women with breast cancer
    Daniel A Monti
    Jefferson Myrna Brind Center of Integrative Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Stress Health 28:397-407. 2012
    ..The results demonstrate that the MBAT programme was associated with significant changes in CBF, which correlated with decreased anxiety over an 8-week period...
  11. ncbi request reprint Striatal dopamine transporter imaging correlates with anxiety and depression symptoms in Parkinson's disease
    Daniel Weintraub
    Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Nucl Med 46:227-32. 2005
    ..We studied the correlation of striatal dopamine transporter (DAT) imaging with anxiety and depression symptoms in Parkinson's disease (PD)...
  12. doi request reprint Double-blind, placebo-controlled, randomized pilot study of cerebral blood flow patterns employing SPECT imaging in dental postsurgical pain patients with and without pain relief
    Andrew B Newberg
    Division of Nuclear Medicine, Department of Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA
    Clin Ther 33:1894-903. 2011
    ..CBF patterns have not been evaluated in patients with acute postoperative pain...
  13. ncbi request reprint Concurrent CBF and CMRGlc changes during human brain activation by combined fMRI-PET scanning
    Andrew B Newberg
    Department of Radiology, University of Pennsylvania Health System, Philadelphia, PA 19104, USA
    Neuroimage 28:500-6. 2005
    ..Although initially validated using a brief, non-quantitative protocol, this approach can provide quantitative CBF and CMRGlc, with a broad range of potential applications in functional physiology and pathophysiology...
  14. ncbi request reprint Safety, biodistribution, and dosimetry of 123I-IMPY: a novel amyloid plaque-imaging agent for the diagnosis of Alzheimer's disease
    Andrew B Newberg
    Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Nucl Med 47:748-54. 2006
    ..The pharmacologic safety profile of the compound was simultaneously assessed...
  15. pmc Chamomile (Matricaria recutita) may provide antidepressant activity in anxious, depressed humans: an exploratory study
    Jay D Amsterdam
    University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Altern Ther Health Med 18:44-9. 2012
    ..Therefore, the identification of inexpensive and effective alternative therapies for anxiety and depression is of relevance to public health...
  16. pmc 123I-ADAM SPECT imaging of serotonin transporter binding in patients with night eating syndrome: a preliminary report
    Jennifer D Lundgren
    Center for Weight and Eating Disorders, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Psychiatry Res 162:214-20. 2008
    ..These findings, in conjunction with the therapeutic response of NES to sertraline, indicate that the serotonin system is involved in the pathophysiology of NES...
  17. doi request reprint Effects of an 8-week meditation program on mood and anxiety in patients with memory loss
    Aleezé Sattar Moss
    Jefferson Myrna Brind Center of Integrative Medicine, Philadelphia, PA 19107, USA
    J Altern Complement Med 18:48-53. 2012
    ..The purpose of this analysis was to assess outcome measures of mood and affect, and also spirituality, and to determine whether or not results correlated with changes in CBF...
  18. doi request reprint Dosimetry of 11C-carfentanil, a micro-opioid receptor imaging agent
    Andrew B Newberg
    Department of Radiology, Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Nucl Med Commun 30:314-8. 2009
    ..The study was conducted within a regulatory framework that required its pharmacological safety to be assessed simultaneously...
  19. pmc Cerebral blood flow effects of yoga training: preliminary evaluation of 4 cases
    Debbie L Cohen
    Department of Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    J Altern Complement Med 15:9-14. 2009
    ..Experienced practitioners of yoga have been shown to alter brain function, but this case series measured cerebral blood flow before and after a 12-week training program in Iyengar yoga (IY) for naïve subjects...
  20. ncbi request reprint Meditation effects on cognitive function and cerebral blood flow in subjects with memory loss: a preliminary study
    Andrew B Newberg
    Division of Nuclear Medicine, Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Alzheimers Dis 20:517-26. 2010
    ..While the findings are encouraging, there are a number of limitations that can be addressed in future studies with more participants and more detailed analyses...
  21. ncbi request reprint Biodistribution and imaging with (123)I-ADAM: a serotonin transporter imaging agent
    Andrew B Newberg
    University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Nucl Med 45:834-41. 2004
    ..The study was conducted within a regulatory framework that required its pharmacologic safety to be assessed simultaneously...
  22. ncbi request reprint A preliminary study of dopamine transporter binding in bipolar and unipolar depressed patients and healthy controls
    Jay D Amsterdam
    Department of Psychiatry, The Depression Research Unit, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Neuropsychobiology 55:167-70. 2007
    ..We hypothesized that DAT levels might be higher in bipolar versus unipolar patients...
  23. doi request reprint Psychosocial benefits of a novel mindfulness intervention versus standard support in distressed women with breast cancer
    Daniel A Monti
    Jefferson Myrna Brind Center of Integrative Medicine, Thomas Jefferson University, Philadelphia, PA, USA
    Psychooncology 22:2565-75. 2013
    ....
  24. ncbi request reprint Neuroimaging in patients with head injury
    Andrew B Newberg
    Division of Nuclear Medicine, Philadelphia, PA 19104, USA
    Semin Nucl Med 33:136-47. 2003
    ..This article will review the current uses of neuroimaging techniques in head trauma and delineate future applications...
  25. ncbi request reprint Early uncoupling of cerebral blood flow and metabolism after bilateral thalamic infarction
    Beau M Ances
    Department of Neurology, University of Pennsylvania, Philadelphia, PA, USA
    AJNR Am J Neuroradiol 25:1685-7. 2004
    ..We chronicled the evolving relationship of blood flow and metabolism with concomitant single photon emission CT and positron emission tomography from the subacute to chronic phase following bilateral thalamic infarction...
  26. ncbi request reprint The role of PET imaging in the management of patients with central nervous system disorders
    Andrew B Newberg
    Division of Nuclear Medicine, Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, 110 Donner Building, Philadelphia, PA 19104, USA
    Radiol Clin North Am 43:49-65. 2005
    ..As such applications become more widely tested, their introduction into the clinical arena will further advance the use of PET imaging in the evaluation and management of CNS disorders...
  27. pmc Direct comparison of fluorodeoxyglucose positron emission tomography and arterial spin labeling magnetic resonance imaging in Alzheimer's disease
    Erik S Musiek
    Department of Neurology, University of Pennsylvania, Philadelphia, USA
    Alzheimers Dement 8:51-9. 2012
    ..Recently, measurement of cerebral blood flow using arterial spin labeling magnetic resonance imaging (ASL-MRI) has shown diagnostic potential in AD, although it has never been directly compared with FDG-PET...
  28. ncbi request reprint Cerebral blood flow effects of pain and acupuncture: a preliminary single-photon emission computed tomography imaging study
    Andrew B Newberg
    Department of Radiology, University of Pennsylvania Health System, Philadelphia, USA
    J Neuroimaging 15:43-9. 2005
    ..The purpose of this study was to investigate the cerebral blood flow changes associated with the analgesic effect of acupuncture in patients with chronic pain...
  29. doi request reprint Current evidence regarding the management of mood and anxiety disorders using complementary and alternative medicine
    Anthony J Bazzan
    Thomas Jefferson University Integrative Medicine, Philadelphia, PA, USA
    Expert Rev Neurother 14:411-23. 2014
    ..There are a growing number of research studies on the effectiveness of CAM interventions in mood and anxiety disorders, and this review evaluates and critiques such data. ..
  30. ncbi request reprint Visual processing impairments and decrements in regional brain activity in Alzheimer's disease
    Salina J van Rhijn
    Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Clin Exp Neuropsychol 26:11-23. 2004
    ....
  31. ncbi request reprint FDG-PET findings in patients with suspected encephalitis
    Bruce Y Lee
    Division of Nuclear Medicine, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Clin Nucl Med 29:620-5. 2004
    ..We explore the role of FDG-PET in the diagnostic evaluation of encephalitis...
  32. doi request reprint Metastatic melanoma causing complete atrioventricular block--the role of FDG PET/CT in diagnosis
    Gang Cheng
    Division of Nuclear Medicine, Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104, USA
    Clin Imaging 35:312-4. 2011
    ..This was confirmed by a repeat myocardial FDG PET scan. In this case report, the role of FDG PET in melanoma patients with cardiac involvement is discussed...
  33. ncbi request reprint Stability of cerebral blood flow measures using a split-dose technique with (99m)Tc-exametazime SPECT
    Andrew B Newberg
    Division of Nuclear Medicine, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
    Nucl Med Commun 26:475-8. 2005
    ..Such a paradigm is frequently used in the clinical and research setting to assess various brain states...
  34. doi request reprint Positron emission tomography in seizure disorders
    Abass Alavi
    University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Ann N Y Acad Sci 1228:E1-E12. 2011
    ....
  35. doi request reprint Complementary and alternative medicine therapies in mood disorders
    Aleeze S Moss
    Myrna Brind Center of Integrative Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Expert Rev Neurother 11:1049-56. 2011
    ..There is an increasing number of research studies on CAM intervention in mood disorders, and this article critiques such data and attempts to provide a clinical perspective within which these CAM interventions might be considered...
  36. pmc Phase I evaluation of intravenous ascorbic acid in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer
    Daniel A Monti
    Myrna Brind Center of Integrative Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 7:e29794. 2012
    ..Preclinical data support further investigation of ascorbic acid in pancreatic cancer. There are currently insufficient safety data in human subjects, particularly when ascorbic acid is combined with chemotherapy...
  37. ncbi request reprint The measurement of regional cerebral blood flow during glossolalia: a preliminary SPECT study
    Andrew B Newberg
    Division of Nuclear Medicine, Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    Psychiatry Res 148:67-71. 2006
    ..This is the first functional neuroimaging study to demonstrate changes in cerebral activity during glossolalia. The frontal lobes, parietal lobes, and left caudate were most affected...
  38. ncbi request reprint PET in seizure disorders
    Andrew B Newberg
    Division of Nuclear Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, 110 Donner Building, Philadelphia, PA 19104, USA
    Radiol Clin North Am 43:79-92. 2005
    ..PET will continue to play a major role, not only in the clinical arena, but also in investigating the pathogenesis and treatment of various seizure disorders...
  39. ncbi request reprint Clinical comparison of 99mTc exametazime and 123I Ioflupane SPECT in patients with chronic mild traumatic brain injury
    Andrew B Newberg
    Myrna Brind Center of Integrative Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 9:e87009. 2014
    ..The goal was to determine how these two different scan might be used and compared to each other in this patient population...
  40. ncbi request reprint Normal patterns and variants in single-photon emission computed tomography and positron emission tomography brain imaging
    Andrew B Newberg
    Division of Nuclear Medicine, Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Semin Nucl Med 33:42-55. 2003
    ....
  41. doi request reprint A preliminary study of the acute effects of religious ritual on anxiety
    Matthew W Anastasi
    University of Pennsylvania, Philadelphia, PA 19104, USA
    J Altern Complement Med 14:163-5. 2008
    ..However, many rituals have multiple components that can account for such effects. Few studies have distinguished between the effects of ritual and those related specifically to religious content and teachings...

Research Grants1