Affiliation: Thomas Jefferson University
- Epidemiology and outcomes of candidemia in 2019 patients: data from the prospective antifungal therapy alliance registryDavid L Horn
Div of Infectious Diseases, Thomas Jefferson University, Ste 210, 211 S 9th St, Philadelphia, PA 19107, USA
Clin Infect Dis 48:1695-703. 2009..Candidemia remains a major cause of morbidity and mortality in the health care setting, and the epidemiology of Candida infection is changing...
- A case of recurrent episodes of Candida parapsilosis fungemiaDionissios Neofytos
Division of Infectious Diseases and Environmental Medicine, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA
Mycopathologia 162:295-8. 2006..The incidence of recurrent candidemia is likely to increase in the near future. Studies and therapeutic interventions for patients at risk for recurrent candidemias are warranted...
- Treatment of adenovirus disease in stem cell transplant recipients with cidofovirDionissios Neofytos
Division of Infectious Diseases and Environment Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
Biol Blood Marrow Transplant 13:74-81. 2007..In conclusion, early treatment of AdV disease with cidofovir inhibits viral replication in vivo and reduces mortality in allogeneic SCT recipients compared with historical data...
- Rhodotorula mucilaginosa catheter-related fungemia in a patient with sickle cell disease: case presentation and literature reviewDionissios Neofytos
Division of Infectious Diseases and Environmental Medicine, Thomas Jefferson University Hospital, 125 South 9th Street, Suite 403, Philadelphia, PA 19107, USA
South Med J 100:198-200. 2007..Rhodotorula mucilaginosa can be a significant, recalcitrant pathogen in immunocompromised patients and prompt treatment should be instituted...
- Emergence of staphylococcal cassette chromosome mec type IV methicillin-resistant Staphylococcus aureus as a cause of ventilator-associated pneumoniaD Neofytos
Division of Infectious Diseases and Environmental Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA
Infect Control Hosp Epidemiol 28:1206-9. 2007..There were no significant differences in VAP severity and crude mortality rates between patients with SCCmec type II strains and patients with SCCmec type IV strains...
- Initial treatment and outcome of Candida glabrata versus Candida albicans bloodstream infectionMichael J Klevay
Department of Medicine, University of Iowa, Iowa City, 52242, USA
Diagn Microbiol Infect Dis 64:152-7. 2009..The lack of difference in mortality between species may reflect the overriding importance of host variables and/or a difference in virulence by species: further study is needed to investigate these hypotheses...
- Epidemiology and outcome of multiple-species candidemia at a tertiary care center between 2004 and 2007Heather L Nace
Temple University School of Medicine, Philadelphia, PA 19140, USA
Diagn Microbiol Infect Dis 64:289-94. 2009..9% and 66.7%, respectively. In this contemporary sampling of patients with MSC, the combination of C. albicans/C. glabrata was most frequently observed and mortality was high...
- Epidemiology and outcomes of Clostridium difficile infections in hematopoietic stem cell transplant recipientsCarolyn D Alonso
Department of Medicine, The Johns Hopkins Hospital, Baltimore, MD 21205, USA
Clin Infect Dis 54:1053-63. 2012..A potentially important interplay between CDI and GVHD involving the gastrointestinal tract was observed...
- Aspergillus osteomyelitis: review of 12 cases identified by the Prospective Antifungal Therapy Alliance registryDavid Horn
Thomas Jefferson University, Philadelphia, PA, USA
Diagn Microbiol Infect Dis 63:384-7. 2009..Voriconazole was commonly administered (11/12; 91.7%), and 9 (75.0%) underwent surgery. Seven (58.3%) responded to treatment, and 12-week mortality was 25.0% (3/12). Survival was improved with surgical intervention (P = 0.05)...
- Candidemia in the 21st centuryAmy Chang
Division of Infectious Diseases, Thomas Jefferson University, Suite 210, 211 South 9th Street, Philadelphia, PA 19107, USA
Future Microbiol 3:463-72. 2008..This review will focus on the changing epidemiology of candidal bloodstream infections, its impact on healthcare and new advances in the diagnosis and treatment of candidemia...
- Presentation of the PATH Alliance registry for prospective data collection and analysis of the epidemiology, therapy, and outcomes of invasive fungal infectionsDavid L Horn
Division of Infectious Diseases, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
Diagn Microbiol Infect Dis 59:407-14. 2007..As enrollment continues, additional data will be analyzed and published, which will provide valuable information concerning the epidemiology, therapy, and outcomes of IFIs...
- Epidemiology, outcomes, and risk factors of invasive fungal infections in adult patients with acute myelogenous leukemia after induction chemotherapyDionissios Neofytos
Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Diagn Microbiol Infect Dis 75:144-9. 2013..Host-related variables (demographics and baseline organ dysfunction) were identified as the most significant risk factors for IFI and mortality predictors in this series...