F T Leone

Summary

Affiliation: Thomas Jefferson University
Country: USA

Publications

  1. ncbi request reprint The utility of peak flow, symptom scores, and beta-agonist use as outcome measures in asthma clinical research
    F T Leone
    Thomas Jefferson University, Philadelphia, PA, USA
    Chest 119:1027-33. 2001
  2. ncbi request reprint Systematic review of the evidence regarding potential complications of inhaled corticosteroid use in asthma: collaboration of American College of Chest Physicians, American Academy of Allergy, Asthma, and Immunology, and American College of Allergy, Asthm
    Frank T Leone
    Jefferson Medical College, Thomas Jefferson University, 1015 Chestnut Street, Suite M100, Philadelphia, PA 19107, USA
    Chest 124:2329-40. 2003
  3. ncbi request reprint The initial attitudes of patients toward longer maintenance hemodialysis
    W J Gaughan
    Department of Medicine, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107, USA
    Clin Nephrol 56:150-4. 2001
  4. ncbi request reprint The solitary pulmonary nodule: not always bronchogenic carcinoma
    Bobbak Vahid
    Department of Pulmonary and Critical Care Medicine, Thomas Jefferson University, 1015 Chestnut Street, Suite M 100, Philadelphia, PA 19107, USA
    Prim Care Respir J 15:256-8. 2006
  5. ncbi request reprint Daily versus as-needed corticosteroids for mild persistent asthma
    Homer A Boushey
    University of California at San Francisco, San Francisco, USA
    N Engl J Med 352:1519-28. 2005
  6. ncbi request reprint Medical symptoms associated with tobacco smoking with and without marijuana abuse among crack cocaine-dependent patients
    Ashwin A Patkar
    Department of Psychiatry and Human Behavior, Department of Medicine, Thomas Jefferson University, Philadelphia, PA, USA
    Am J Addict 14:43-53. 2005
  7. ncbi request reprint Tobacco smoking: current concepts in etiology and treatment
    Ashwin A Patkar
    Department of Psychiatry, Thomas Jefferson University, 33 South 9th Street, Suite 210E, Philadelphia, PA 19107, USA
    Psychiatry 66:183-99. 2003
  8. ncbi request reprint A comparison of smoking habits among medical and nursing students
    Ashwin A Patkar
    Department of Psychiatry and Human Behavior, Jefferson Medical College and Thomas Jefferson University, Philadelphia, PA 19107, USA
    Chest 124:1415-20. 2003
  9. ncbi request reprint Nicotine dependence and treatment outcome among African American cocaine-dependent patients
    Ashwin A Patkar
    Department of Psychiatry and Human Behavior, Thomas Jefferson University, Philadelphia, PA, USA
    Nicotine Tob Res 5:411-8. 2003
  10. ncbi request reprint The genetic determinants of smoking
    Vikas Batra
    Department of Medicine, Division of Critical Care, Pulmonary, Allergic and Immunologic Diseases, Thomas Jefferson University, Philadelphia, USA
    Chest 123:1730-9. 2003

Research Grants

  1. ASTHMA CLINICAL RESEARCH NETWORK
    Frank Leone; Fiscal Year: 2002

Detail Information

Publications22

  1. ncbi request reprint The utility of peak flow, symptom scores, and beta-agonist use as outcome measures in asthma clinical research
    F T Leone
    Thomas Jefferson University, Philadelphia, PA, USA
    Chest 119:1027-33. 2001
    ..It remains unclear, however, as to which surrogate markers of disease status are discriminative indicators of treatment failure, suitable for use in clinical trials...
  2. ncbi request reprint Systematic review of the evidence regarding potential complications of inhaled corticosteroid use in asthma: collaboration of American College of Chest Physicians, American Academy of Allergy, Asthma, and Immunology, and American College of Allergy, Asthm
    Frank T Leone
    Jefferson Medical College, Thomas Jefferson University, 1015 Chestnut Street, Suite M100, Philadelphia, PA 19107, USA
    Chest 124:2329-40. 2003
    ....
  3. ncbi request reprint The initial attitudes of patients toward longer maintenance hemodialysis
    W J Gaughan
    Department of Medicine, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107, USA
    Clin Nephrol 56:150-4. 2001
    ..Male gender was associated with a positive response (p = 0.03). Various suggested and spontaneous reasons were given for a negative response...
  4. ncbi request reprint The solitary pulmonary nodule: not always bronchogenic carcinoma
    Bobbak Vahid
    Department of Pulmonary and Critical Care Medicine, Thomas Jefferson University, 1015 Chestnut Street, Suite M 100, Philadelphia, PA 19107, USA
    Prim Care Respir J 15:256-8. 2006
    ..4% of all lymphomas. We present a case of primary pulmonary non-Hodgkins lymphoma which presented as a SLN in an 87-year old lady with a smoking history of 50 pack years...
  5. ncbi request reprint Daily versus as-needed corticosteroids for mild persistent asthma
    Homer A Boushey
    University of California at San Francisco, San Francisco, USA
    N Engl J Med 352:1519-28. 2005
    ....
  6. ncbi request reprint Medical symptoms associated with tobacco smoking with and without marijuana abuse among crack cocaine-dependent patients
    Ashwin A Patkar
    Department of Psychiatry and Human Behavior, Department of Medicine, Thomas Jefferson University, Philadelphia, PA, USA
    Am J Addict 14:43-53. 2005
    ..Tobacco smoking was not related to changes in cocaine use. Also, marijuana smoking does not appear to be associated with a reduction in tobacco or cocaine use...
  7. ncbi request reprint Tobacco smoking: current concepts in etiology and treatment
    Ashwin A Patkar
    Department of Psychiatry, Thomas Jefferson University, 33 South 9th Street, Suite 210E, Philadelphia, PA 19107, USA
    Psychiatry 66:183-99. 2003
    ..It also makes recommendations for the rational use of these interventions to treat nicotine dependence in individuals with psychiatric disorders...
  8. ncbi request reprint A comparison of smoking habits among medical and nursing students
    Ashwin A Patkar
    Department of Psychiatry and Human Behavior, Jefferson Medical College and Thomas Jefferson University, Philadelphia, PA 19107, USA
    Chest 124:1415-20. 2003
    ..We compared smoking habits among medical and nursing students, and examined whether these habits changed during the course of education for each cohort...
  9. ncbi request reprint Nicotine dependence and treatment outcome among African American cocaine-dependent patients
    Ashwin A Patkar
    Department of Psychiatry and Human Behavior, Thomas Jefferson University, Philadelphia, PA, USA
    Nicotine Tob Res 5:411-8. 2003
    ..It seems that severity of tobacco use predicts poor outcome for cocaine-dependent patients who are cocaine free at the time of admission into outpatient treatment...
  10. ncbi request reprint The genetic determinants of smoking
    Vikas Batra
    Department of Medicine, Division of Critical Care, Pulmonary, Allergic and Immunologic Diseases, Thomas Jefferson University, Philadelphia, USA
    Chest 123:1730-9. 2003
    ..Insights into the genetic contributions to smoking can potentially lead to more effective strategies to reduce smoking...
  11. ncbi request reprint Relationship between tobacco smoking and medical symptoms among cocaine-, alcohol-, and opiate-dependent patients
    Ashwin A Patkar
    Division of Substance Abuse Programs, Department of Psychiatry, Jefferson Medical College and Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
    Am J Addict 11:209-18. 2002
    ..In particular, cocaine patients seem to be affected differently than alcohol and opiate patients...
  12. ncbi request reprint Relationship between tobacco smoking and positive and negative symptoms in schizophrenia
    Ashwin A Patkar
    Department of Psychiatry and Human Behavior, Thomas Jefferson University, 833 Chestnut Street East, Suite 210E, Philadelphia, Pennsylvania, 19107, USA
    J Nerv Ment Dis 190:604-10. 2002
    ..A combination of negative symptoms, duration of illness, and alcohol use optimally predicted smoking in the sample. Neurobiological mechanisms could possibly underlie some of our findings and require further investigation...
  13. ncbi request reprint Tobacco and alcohol use and medical symptoms among cocaine dependent patients
    Ashwin A Patkar
    Department of Psychiatry, Jefferson Medical College and Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA
    Subst Abus 23:105-14. 2002
    ....
  14. ncbi request reprint Tobacco smoking as a chronic disease: notes on prevention and treatment
    Vikas Batra
    Division of Critical Care, Pulmonary, Allergic and Immunologic Diseases, Thomas Jefferson University, 1025 Walnut Street, 805 College Bldg, Philadelphia, PA 19107, USA
    Prim Care 29:629-48. 2002
    ..Physicians who take steps to engage in local public health initiatives are likely to magnify the effects of their efforts at the bedside [148, 149]...
  15. ncbi request reprint Differences in platelet serotonin transporter sites between African-American tobacco smokers and non-smokers
    Ashwin A Patkar
    Department of Psychiatry and Human Behavior, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Psychopharmacology (Berl) 166:221-7. 2003
    ..Although nicotine and other constituents of tobacco smoke may influence serotonin turnover among animals, few studies have examined whether smoking is associated with alteration in 5HTT in humans...
  16. ncbi request reprint Lung cancer: the oncologist's role in smoking cessation
    Rohit Ahuja
    Division of Critical Care, Pulmonary, Allergic and Immunologic Diseases, Thomas Jefferson University, Jefferson Medical College, Philadelphia, PA 19107, USA
    Semin Oncol 30:94-103. 2003
    ..Pharmacologic and behavioral interventions for smokers, including the role of nicotine replacement therapies and bupropion, and their relevance to oncologic practice are reviewed...
  17. ncbi request reprint Do physicians in Delaware follow national guidelines for tobacco counseling?
    James M Gill
    Health Services Research, Christiana Care Health Services, Newark, Delaware, USA
    Del Med J 76:297-308. 2004
    ..This survey study examined tobacco cessation behaviors among physicians in Delaware as part of the state's tobacco control program called Plan for a Tobacco-Free Delaware...
  18. ncbi request reprint Changes in tobacco smoking following treatment for cocaine dependence
    Ashwin A Patkar
    Department of Psychiatry Behavioral Sciences, Duke University, Durham, North Carolina 27704, USA
    Am J Drug Alcohol Abuse 32:135-48. 2006
    ..There is no evidence that reduction in crack cocaine smoking following treatment is accompanied by an increase in tobacco smoking. It appears that concerns over tobacco being substituted for cocaine may be unfounded in this population...
  19. ncbi request reprint Teaching smoking cessation: an expert interview with Vikas Batra, MD, and Frank T. Leone, MD
    Vikas Batra
    MedGenMed 4:24. 2002
  20. pmc Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthma
    Stephen C Lazarus
    University of California, San Francisco, 505 Parnassus Avenue, M 1083, San Francisco, CA 94143 0111, USA
    Am J Respir Crit Care Med 175:783-90. 2007
    ..One-quarter to one-third of individuals with asthma smoke, which may affect response to therapy and contribute to poor asthma control...
  21. pmc The Predicting Response to Inhaled Corticosteroid Efficacy (PRICE) trial
    Richard J Martin
    National Jewish Medical and Research Center, Denver, CO 80206, USA
    J Allergy Clin Immunol 119:73-80. 2007
    ..Although guidelines recommend anti-inflammatory therapy for persistent asthma, recent studies suggest that 25% to 35% of patients with asthma may not improve lung function with inhaled corticosteroids...
  22. ncbi request reprint The efficacy and safety of varenicline for smoking cessation using a flexible dosing strategy in adult smokers: a randomized controlled trial
    Raymond Niaura
    Brown University, Providence, RI, USA
    Curr Med Res Opin 24:1931-41. 2008
    ..To determine whether self-regulated flexible dosing with varenicline tartrate is safe and effective for smoking cessation...

Research Grants1

  1. ASTHMA CLINICAL RESEARCH NETWORK
    Frank Leone; Fiscal Year: 2002
    ..Other planned studies are also briefly discussed, with the understanding that they could be modified or replaced in response to new information, new therapies, or changing clinical research priorities. ..