Research Topics
| F P GasparroSummaryAffiliation: Thomas Jefferson University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Psoralen photochemotherapy, clinical efficacy, and photomutagenicity: the role of molecular epidemiology in minimizing risksF P Gasparro
Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA
Environ Mol Mutagen 31:105-12. 1998..Thus, the PUVA SCC may have arisen from the solar mutations and PUVA may enhance tumor progression by other epigenetic effects...
The role of PUVA in the treatment of psoriasis. Photobiology issues related to skin cancer incidenceF P Gasparro
Photobiology Laboratory, Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Am J Clin Dermatol 1:337-48. 2000..To relate clinical observations to molecular events, the nature of p53 mutations found in skin cancers from psoriasis patients is also analyzed. Finally some suggestions for improving the delivery of PUVA therapy are presented...
Photodermatology: progress, problems and prospectsF P Gasparro
Department of Dermatology, Thomas Jefferson University, Philadelphia, PA 19107, USA
Eur J Dermatol 10:250-4. 2000..This review is structured so as to report on recent progress, existing problem areas and prospects for advances in the near future...
Sunscreens, skin photobiology, and skin cancer: the need for UVA protection and evaluation of efficacyF P Gasparro
Photobiology Laboratory, Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
Environ Health Perspect 108:71-8. 2000..It is proposed that SPF ("sun" protection factor) be renamed "sunburn" protection factor and that "critical wavelength" be designated "long wave index."..
Psoralen photobiology and photochemotherapy: 50 years of science and medicineD Bethea
Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA
J Dermatol Sci 19:78-88. 1999..These will be surveyed in this review commemorating the 50 years of modern psoralen photobiology and photomedicine...
A review of sunscreen safety and efficacyF P Gasparro
Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA
Photochem Photobiol 68:243-56. 1998..Further, the regular use of appropriate broad-spectrum sunscreen products could have a significant and favorable impact on public health as part of an overall strategy to reduce UVR exposure...
The nitroxide Tempol affords protection against ultraviolet radiation in a transgenic murine fibroblast culture model of cutaneous photoagingE F Bernstein
Department of Dermatology and Cutaneous Biology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA
Exp Dermatol 10:55-61. 2001..These results demonstrate the ability of the superoxide dismutase mimic, Tempol, to protect against ultraviolet induced elastin promoter activation. This compound could be a useful pharmacological agent to prevent cutaneous photoaging...
Ultraviolet-filtering properties of commonly used tissue cell culture plasticwareD B Brown
Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, PA, USA
Photodermatol Photoimmunol Photomed 17:126-9. 2001..In addition, in vitro experiments utilizing filtered fluorescent sunlamps require the removal of plastic tissue cell culture lids, increasing the possibility of contamination...
Kinetic analysis of apoptosis induction in human cell lines by UVA and 8-MOPB R Vowels
Department of Dermatology, School of Medicine, University of Pennsylvania, Philidelphia 19104 6142, USA
Photochem Photobiol 63:572-6. 1996..This correlation provides an important tool for studying the relationship of UVA-induced DNA damage to apoptosis induction. moreover, it will provide a means by which early events in the apoptotic pathway can be dissected...
UVA-340 as energy source, mimicking natural sunlight, activates the transcription factor AP-1 in cultured fibroblasts: evidence for involvement of protein kinase-CH Nakano
Departments of Dermatology and Cutaneous Biology and Biochemistry and Molecular Pharmacology, Jefferson Medical College, Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, PA, USA
Photochem Photobiol 74:274-82. 2001..Collectively, these results suggest that AP-1 is an important mediator of UVR action in fibroblasts...
Keratinocyte apoptosis induced by ultraviolet B radiation and CD95 ligation -- differential protection through epidermal growth factor receptor activation and Bcl-x(L) expressionM Jost
Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, and Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania
J Invest Dermatol 116:860-6. 2001....
