C T Derk

Summary

Affiliation: Thomas Jefferson University
Country: USA

Publications

  1. ncbi A case of anti-Jo1 myositis with pleural effusions and pericardial tamponade developing after exposure to a fermented Kombucha beverage
    Chris T Derk
    Division of Rheumatology, Thomas Jefferson University Hospital, Philadelphia, PA 1910, USA
    Clin Rheumatol 23:355-7. 2004
  2. ncbi Goodpasture-like syndrome induced by D-penicillamine in a patient with systemic sclerosis: report and review of the literature
    Chris T Derk
    Division of Rheumatology, Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107 5541, USA
    J Rheumatol 30:1616-20. 2003
  3. ncbi Autoantibodies in patients with systemic sclerosis and cancer: a case-control study
    Chris T Derk
    Division of Rheumatology, Department of Medicine, Thomas Jefferson University, 233 South 10th Street, 509 BLSB, Philadelphia, PA 19107, USA
    J Rheumatol 30:1994-6. 2003
  4. ncbi Inclusion body myositis in connective tissue disorders: case report and review of the literature
    C T Derk
    Thomas Jefferson University Hospital, Pennsylvania, Philadelphia, USA
    Clin Rheumatol 22:324-8. 2003
  5. ncbi Primary B-cell lymphoma of the tongue in a patient with systemic sclerosis
    Chris T Derk
    Division of Rheumatology, Thomas Jefferson University, 613 Curtis Bldg, 1015 Walnut Street, Philadelphia, PA 19107, USA
    Oral Oncol 40:103-6. 2004
  6. doi The spectrum of clinical manifestations, outcome and treatment of pericardial tamponade in patients with systemic lupus erythematosus: a retrospective study and literature review
    E Rosenbaum
    Division of Rheumatology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107 5541, USA
    Lupus 18:608-12. 2009
  7. doi A retrospective randomly selected cohort study of D-penicillamine treatment in rapidly progressive diffuse cutaneous systemic sclerosis of recent onset
    C T Derk
    Division of Rheumatology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Br J Dermatol 158:1063-8. 2008
  8. ncbi Systemic sclerosis at the cellular level: molecular pathways of pathogenesis and its implication on future drug design
    S W Schulz
    Division of Rheumatology, Thomas Jefferson University, 613 Curtis Bldg, 1015 Walnut Street, Philadelphia, PA 19107, USA
    Curr Med Chem 16:3986-95. 2009
  9. ncbi Septic arthritis caused by Actinobacillus ureae in a patient with rheumatoid arthritis receiving anti-tumor necrosis factor-alpha therapy
    Primal P Kaur
    Division of Rheumatology, Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    J Rheumatol 31:1663-5. 2004
  10. doi Eosinophilic fasciitis: demographics, disease pattern and response to treatment: report of 12 cases and review of the literature
    Lindsay Bischoff
    Jefferson Medical College, Philadelphia PA, 19107, USA
    Int J Dermatol 47:29-35. 2008

Detail Information

Publications25

  1. ncbi A case of anti-Jo1 myositis with pleural effusions and pericardial tamponade developing after exposure to a fermented Kombucha beverage
    Chris T Derk
    Division of Rheumatology, Thomas Jefferson University Hospital, Philadelphia, PA 1910, USA
    Clin Rheumatol 23:355-7. 2004
    ..Kombucha 'mushroom', a symbiosis of yeast and bacteria, is postulated to be the trigger for our patient's disease owing to the proximity of his symptoms to the consumption of the Kombucha beverage...
  2. ncbi Goodpasture-like syndrome induced by D-penicillamine in a patient with systemic sclerosis: report and review of the literature
    Chris T Derk
    Division of Rheumatology, Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107 5541, USA
    J Rheumatol 30:1616-20. 2003
    ..We review the cases reported to date in the literature and describe the clinical characteristics, therapy, and outcome of this group of patients...
  3. ncbi Autoantibodies in patients with systemic sclerosis and cancer: a case-control study
    Chris T Derk
    Division of Rheumatology, Department of Medicine, Thomas Jefferson University, 233 South 10th Street, 509 BLSB, Philadelphia, PA 19107, USA
    J Rheumatol 30:1994-6. 2003
    ..To determine the prevalence of specific autoantibodies in a cohort of patients with systemic sclerosis (SSc) and a diagnosis of cancer, and to compare it to that in a group of patients with SSc who were never diagnosed with cancer...
  4. ncbi Inclusion body myositis in connective tissue disorders: case report and review of the literature
    C T Derk
    Thomas Jefferson University Hospital, Pennsylvania, Philadelphia, USA
    Clin Rheumatol 22:324-8. 2003
    ..This is the first case report of IBM in a patient who had the dual diagnosis of SLE and SS...
  5. ncbi Primary B-cell lymphoma of the tongue in a patient with systemic sclerosis
    Chris T Derk
    Division of Rheumatology, Thomas Jefferson University, 613 Curtis Bldg, 1015 Walnut Street, Philadelphia, PA 19107, USA
    Oral Oncol 40:103-6. 2004
    ..A careful review of the English medical literature disclosed that B-cell lymphoma of the tongue in a patient with systemic sclerosis is an association which has not been described previously...
  6. doi The spectrum of clinical manifestations, outcome and treatment of pericardial tamponade in patients with systemic lupus erythematosus: a retrospective study and literature review
    E Rosenbaum
    Division of Rheumatology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107 5541, USA
    Lupus 18:608-12. 2009
    ..A low C4 level at presentation was predictive of the development of tamponade physiology...
  7. doi A retrospective randomly selected cohort study of D-penicillamine treatment in rapidly progressive diffuse cutaneous systemic sclerosis of recent onset
    C T Derk
    Division of Rheumatology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Br J Dermatol 158:1063-8. 2008
    ..Several uncontrolled studies in systemic sclerosis have shown that D-penicillamine may cause improvement in skin sclerosis, decrease the rate of new visceral organ involvement, and improve overall survival...
  8. ncbi Systemic sclerosis at the cellular level: molecular pathways of pathogenesis and its implication on future drug design
    S W Schulz
    Division of Rheumatology, Thomas Jefferson University, 613 Curtis Bldg, 1015 Walnut Street, Philadelphia, PA 19107, USA
    Curr Med Chem 16:3986-95. 2009
    ..Such knowledge will help us to further current treatments options and design novel therapies for Systemic Sclerosis and other fibrotic disorders...
  9. ncbi Septic arthritis caused by Actinobacillus ureae in a patient with rheumatoid arthritis receiving anti-tumor necrosis factor-alpha therapy
    Primal P Kaur
    Division of Rheumatology, Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    J Rheumatol 31:1663-5. 2004
    ..We describe a case of septic arthritis and abscess formation caused by this unusual organism in a patient with rheumatoid arthritis, who was being treated with tumor necrosis factor-alpha inhibitors...
  10. doi Eosinophilic fasciitis: demographics, disease pattern and response to treatment: report of 12 cases and review of the literature
    Lindsay Bischoff
    Jefferson Medical College, Philadelphia PA, 19107, USA
    Int J Dermatol 47:29-35. 2008
    ..Eosinophilic fasciitis is a rare scleroderma-like illness. The clinical spectrum of the disease has evolved since its initial description...
  11. ncbi Rheumatoid arthritis: an update
    Chris T Derk
    Division of Rheumatology, Department of Medicine, at Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Del Med J 77:59-63. 2005
    ..Improved understanding of the molecular mechanisms involved in the pathogenesis of rheumatoid arthritis has led to long awaited, highly effective treatments for this disorder...
  12. ncbi Morbidity and mortality of patients diagnosed with systemic sclerosis after the age of 75: a nested case-control study
    Chris T Derk
    Department of Medicine, Division of Rheumatology, Thomas Jefferson University, Philadelphia, PA, 19017, USA
    Clin Rheumatol 25:831-4. 2006
    ..A higher clinical suspicion will lead to an earlier diagnosis and a potential decrease in morbidity and mortality...
  13. ncbi A cohort study of cancer incidence in systemic sclerosis
    Chris T Derk
    Division of Rhematology, Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    J Rheumatol 33:1113-6. 2006
    ..To describe the incidence of cancer in a large cohort of patients with systemic sclerosis (SSc) and compare it to the Surveillance Epidemiology and End Results (SEER) cancer registries...
  14. ncbi The use of mycophenolate mofetil for the treatment of systemic sclerosis
    Max Shenin
    Division of Rheumatology, Thomas Jefferson University, 613 Curtis Bldg, 1015 Walnut Street, Philadelphia, PA 19107, USA
    Endocr Metab Immune Disord Drug Targets 8:11-4. 2008
    ..Disease modification early on during the inflammatory stage of systemic sclerosis may lead to an overall decrease in fibrotic complications both in relation to cutaneous and internal organ involvement...
  15. pmc Development of a provisional core set of response measures for clinical trials of systemic sclerosis
    D Khanna
    Division of Rheumatology, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, California 90095, USA
    Ann Rheum Dis 67:703-9. 2008
    ..To develop a provisional core set of response measures for clinical trials of systemic sclerosis (SSc)...
  16. ncbi Systemic sclerosis mortality in the United States: 1999-2002 implications for patient care
    Fabian Mendoza
    Division of Rheumatology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107 5541, USA
    J Clin Rheumatol 13:187-92. 2007
    ..To describe the systemic sclerosis mortality rates in the United States between 1999 and 2002, a time period in which a new coding system was used to record deaths, and to describe its implications in patient care...
  17. ncbi Associations of breast cancer development in patients with systemic sclerosis: an exploratory study
    Chris T Derk
    Division of Rheumatology, Department of Medicine, Thomas Jefferson University, 613 Curtis Bldg, 1015 Walnut Street, Philadelphia, PA 19107 5541, USA
    Clin Rheumatol 26:1615-9. 2007
    ..9 +/- 13.5) (p = 0.03). An older age at diagnosis of systemic sclerosis, a lack of ANA positivity, and the presence of pulmonary fibrosis were more commonly seen in patients with systemic sclerosis who have a diagnosis of breast cancer...
  18. ncbi Osteoporosis in premenopause. When are screening and treatment prudent?
    Chris T Derk
    Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Postgrad Med 119:8-15. 2006
    ..In this article, Dr Derk identifies high-risk groups, presents an approach to judicious screening, and recommends prevention and treatment strategies...
  19. ncbi Acute myocardial infarction in systemic sclerosis patients: a case series
    Chris T Derk
    Division of Rheumatology, Thomas Jefferson University, 613 Curtis Bldg, 1015 Walnut Street, Philadelphia, PA 19107 5541, USA
    Clin Rheumatol 26:965-8. 2007
    ..Normal coronaries are seen more commonly in these patients as compared to the general population, while vascular, gastrointestinal, and renal involvement is prevalent in these patients...
  20. ncbi Statins and the vasculopathy of systemic sclerosis: potential therapeutic agents?
    Chris T Derk
    Division of Rheumatology, Department of Medicine, Thomas Jefferson University, 613 Curtis Bldg, 1015 Walnut Street, Philadelphia, PA 19107 5541, USA
    Autoimmun Rev 5:25-32. 2006
    ..Here, we review the current literature, which suggests that statins may have a modifying effect on the vasculopathy of systemic sclerosis...
  21. ncbi Increased incidence of carcinoma of the tongue in patients with systemic sclerosis
    Chris T Derk
    Division of Rheumatology, Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    J Rheumatol 32:637-41. 2005
    ..To describe the incidence of carcinoma of the tongue in a large cohort of patients with systemic sclerosis (SSc)...
  22. ncbi A primary care approach to Sjögren's syndrome. Helping patients cope with sicca symptoms, extraglandular manifestations
    Chris T Derk
    Department of Internal Medicine, Division of Rheumatology, Thomas Jefferson University, Philadelphia, PA 19107 5099, USA
    Postgrad Med 116:49-54, 59, 65. 2004
    ..In this article, Drs Derk and Vivino review the criteria for diagnosis, common signs and symptoms, and strategies for increasing patient comfort...
  23. ncbi Systemic lupus erythematosus and acute pancreatitis: a case series
    Chris T Derk
    Division of Rheumatology, Department of Medicine, Thomas Jefferson University, 613 Curtis Bldg, 1015 Walnut Street, Philadelphia, PA 19107, USA
    Clin Rheumatol 23:147-51. 2004
    ..We therefore concluded that acute pancreatitis is a rare manifestation of systemic lupus erythematosus, and corticosteroids do not appear to be the etiological agent...
  24. ncbi Following the molecular pathways toward an understanding of the pathogenesis of systemic sclerosis
    Sergio A Jimenez
    Division of Rheumatology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107 5541, USA
    Ann Intern Med 140:37-50. 2004
  25. ncbi Systemic sclerosis: current views of its pathogenesis
    Chris T Derk
    Department of Medicine, Division of Rheumatology, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Autoimmun Rev 2:181-91. 2003
    ..A better understanding of the pathogenesis of this incurable disorder will help to better target and design effective therapy in the future...