Research Topics
| C T DerkSummaryAffiliation: Thomas Jefferson University Country: USA Publications
| Collaborators
|
Detail Information
Publications
A case of anti-Jo1 myositis with pleural effusions and pericardial tamponade developing after exposure to a fermented Kombucha beverageChris T Derk
Division of Rheumatology, Thomas Jefferson University Hospital, Philadelphia, PA 1910, USA
Clin Rheumatol 23:355-7. 2004..Kombucha 'mushroom', a symbiosis of yeast and bacteria, is postulated to be the trigger for our patient's disease owing to the proximity of his symptoms to the consumption of the Kombucha beverage...- Goodpasture-like syndrome induced by D-penicillamine in a patient with systemic sclerosis: report and review of the literatureChris T Derk
Division of Rheumatology, Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107 5541, USA
J Rheumatol 30:1616-20. 2003..We review the cases reported to date in the literature and describe the clinical characteristics, therapy, and outcome of this group of patients... - Autoantibodies in patients with systemic sclerosis and cancer: a case-control studyChris T Derk
Division of Rheumatology, Department of Medicine, Thomas Jefferson University, 233 South 10th Street, 509 BLSB, Philadelphia, PA 19107, USA
J Rheumatol 30:1994-6. 2003..To determine the prevalence of specific autoantibodies in a cohort of patients with systemic sclerosis (SSc) and a diagnosis of cancer, and to compare it to that in a group of patients with SSc who were never diagnosed with cancer... - Inclusion body myositis in connective tissue disorders: case report and review of the literatureC T Derk
Thomas Jefferson University Hospital, Pennsylvania, Philadelphia, USA
Clin Rheumatol 22:324-8. 2003..This is the first case report of IBM in a patient who had the dual diagnosis of SLE and SS... - Primary B-cell lymphoma of the tongue in a patient with systemic sclerosisChris T Derk
Division of Rheumatology, Thomas Jefferson University, 613 Curtis Bldg, 1015 Walnut Street, Philadelphia, PA 19107, USA
Oral Oncol 40:103-6. 2004..A careful review of the English medical literature disclosed that B-cell lymphoma of the tongue in a patient with systemic sclerosis is an association which has not been described previously... 
The spectrum of clinical manifestations, outcome and treatment of pericardial tamponade in patients with systemic lupus erythematosus: a retrospective study and literature reviewE Rosenbaum
Division of Rheumatology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107 5541, USA
Lupus 18:608-12. 2009..A low C4 level at presentation was predictive of the development of tamponade physiology...- A retrospective randomly selected cohort study of D-penicillamine treatment in rapidly progressive diffuse cutaneous systemic sclerosis of recent onsetC T Derk
Division of Rheumatology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA
Br J Dermatol 158:1063-8. 2008..Several uncontrolled studies in systemic sclerosis have shown that D-penicillamine may cause improvement in skin sclerosis, decrease the rate of new visceral organ involvement, and improve overall survival... - Systemic sclerosis at the cellular level: molecular pathways of pathogenesis and its implication on future drug designS W Schulz
Division of Rheumatology, Thomas Jefferson University, 613 Curtis Bldg, 1015 Walnut Street, Philadelphia, PA 19107, USA
Curr Med Chem 16:3986-95. 2009..Such knowledge will help us to further current treatments options and design novel therapies for Systemic Sclerosis and other fibrotic disorders... - Septic arthritis caused by Actinobacillus ureae in a patient with rheumatoid arthritis receiving anti-tumor necrosis factor-alpha therapyPrimal P Kaur
Division of Rheumatology, Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
J Rheumatol 31:1663-5. 2004..We describe a case of septic arthritis and abscess formation caused by this unusual organism in a patient with rheumatoid arthritis, who was being treated with tumor necrosis factor-alpha inhibitors... - Eosinophilic fasciitis: demographics, disease pattern and response to treatment: report of 12 cases and review of the literatureLindsay Bischoff
Jefferson Medical College, Philadelphia PA, 19107, USA
Int J Dermatol 47:29-35. 2008..Eosinophilic fasciitis is a rare scleroderma-like illness. The clinical spectrum of the disease has evolved since its initial description... - Rheumatoid arthritis: an updateChris T Derk
Division of Rheumatology, Department of Medicine, at Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Del Med J 77:59-63. 2005..Improved understanding of the molecular mechanisms involved in the pathogenesis of rheumatoid arthritis has led to long awaited, highly effective treatments for this disorder... - Morbidity and mortality of patients diagnosed with systemic sclerosis after the age of 75: a nested case-control studyChris T Derk
Department of Medicine, Division of Rheumatology, Thomas Jefferson University, Philadelphia, PA, 19017, USA
Clin Rheumatol 25:831-4. 2006..A higher clinical suspicion will lead to an earlier diagnosis and a potential decrease in morbidity and mortality... - A cohort study of cancer incidence in systemic sclerosisChris T Derk
Division of Rhematology, Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
J Rheumatol 33:1113-6. 2006..To describe the incidence of cancer in a large cohort of patients with systemic sclerosis (SSc) and compare it to the Surveillance Epidemiology and End Results (SEER) cancer registries... - The use of mycophenolate mofetil for the treatment of systemic sclerosisMax Shenin
Division of Rheumatology, Thomas Jefferson University, 613 Curtis Bldg, 1015 Walnut Street, Philadelphia, PA 19107, USA
Endocr Metab Immune Disord Drug Targets 8:11-4. 2008..Disease modification early on during the inflammatory stage of systemic sclerosis may lead to an overall decrease in fibrotic complications both in relation to cutaneous and internal organ involvement... - Development of a provisional core set of response measures for clinical trials of systemic sclerosisD Khanna
Division of Rheumatology, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, California 90095, USA
Ann Rheum Dis 67:703-9. 2008..To develop a provisional core set of response measures for clinical trials of systemic sclerosis (SSc)... - Systemic sclerosis mortality in the United States: 1999-2002 implications for patient careFabian Mendoza
Division of Rheumatology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107 5541, USA
J Clin Rheumatol 13:187-92. 2007..To describe the systemic sclerosis mortality rates in the United States between 1999 and 2002, a time period in which a new coding system was used to record deaths, and to describe its implications in patient care... - Associations of breast cancer development in patients with systemic sclerosis: an exploratory studyChris T Derk
Division of Rheumatology, Department of Medicine, Thomas Jefferson University, 613 Curtis Bldg, 1015 Walnut Street, Philadelphia, PA 19107 5541, USA
Clin Rheumatol 26:1615-9. 2007..9 +/- 13.5) (p = 0.03). An older age at diagnosis of systemic sclerosis, a lack of ANA positivity, and the presence of pulmonary fibrosis were more commonly seen in patients with systemic sclerosis who have a diagnosis of breast cancer... - Osteoporosis in premenopause. When are screening and treatment prudent?Chris T Derk
Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA
Postgrad Med 119:8-15. 2006..In this article, Dr Derk identifies high-risk groups, presents an approach to judicious screening, and recommends prevention and treatment strategies... - Acute myocardial infarction in systemic sclerosis patients: a case seriesChris T Derk
Division of Rheumatology, Thomas Jefferson University, 613 Curtis Bldg, 1015 Walnut Street, Philadelphia, PA 19107 5541, USA
Clin Rheumatol 26:965-8. 2007..Normal coronaries are seen more commonly in these patients as compared to the general population, while vascular, gastrointestinal, and renal involvement is prevalent in these patients... - Statins and the vasculopathy of systemic sclerosis: potential therapeutic agents?Chris T Derk
Division of Rheumatology, Department of Medicine, Thomas Jefferson University, 613 Curtis Bldg, 1015 Walnut Street, Philadelphia, PA 19107 5541, USA
Autoimmun Rev 5:25-32. 2006..Here, we review the current literature, which suggests that statins may have a modifying effect on the vasculopathy of systemic sclerosis... - Increased incidence of carcinoma of the tongue in patients with systemic sclerosisChris T Derk
Division of Rheumatology, Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
J Rheumatol 32:637-41. 2005..To describe the incidence of carcinoma of the tongue in a large cohort of patients with systemic sclerosis (SSc)... - A primary care approach to Sjögren's syndrome. Helping patients cope with sicca symptoms, extraglandular manifestationsChris T Derk
Department of Internal Medicine, Division of Rheumatology, Thomas Jefferson University, Philadelphia, PA 19107 5099, USA
Postgrad Med 116:49-54, 59, 65. 2004..In this article, Drs Derk and Vivino review the criteria for diagnosis, common signs and symptoms, and strategies for increasing patient comfort... - Systemic lupus erythematosus and acute pancreatitis: a case seriesChris T Derk
Division of Rheumatology, Department of Medicine, Thomas Jefferson University, 613 Curtis Bldg, 1015 Walnut Street, Philadelphia, PA 19107, USA
Clin Rheumatol 23:147-51. 2004..We therefore concluded that acute pancreatitis is a rare manifestation of systemic lupus erythematosus, and corticosteroids do not appear to be the etiological agent... - Following the molecular pathways toward an understanding of the pathogenesis of systemic sclerosisSergio A Jimenez
Division of Rheumatology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107-5541, USA
Ann Intern Med 140:37-50. 2004 - Systemic sclerosis: current views of its pathogenesisChris T Derk
Department of Medicine, Division of Rheumatology, Thomas Jefferson University, Philadelphia, PA 19107, USA
Autoimmun Rev 2:181-91. 2003..A better understanding of the pathogenesis of this incurable disorder will help to better target and design effective therapy in the future...