Inna Chervoneva

Summary

Affiliation: Thomas Jefferson University
Country: USA

Publications

  1. ncbi request reprint Relative quantification based on logistic models for individual polymerase chain reactions
    Inna Chervoneva
    Division of Biostatistics, Department of Clinical Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Stat Med 26:5596-611. 2007
  2. ncbi request reprint Statistical algorithm for assuring similar efficiency in standards and samples for absolute quantification by real-time reverse transcription polymerase chain reaction
    Inna Chervoneva
    Division of Biostatistics, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Anal Biochem 348:198-208. 2006
  3. pmc Increased SIAH expression predicts ductal carcinoma in situ (DCIS) progression to invasive carcinoma
    Kathryn C Behling
    Department of Pathology, Thomas Jefferson University and Kimmel Cancer Center, Philadelphia, PA 19107, USA
    Breast Cancer Res Treat 129:717-24. 2011
  4. pmc Selection of optimal reference genes for normalization in quantitative RT-PCR
    Inna Chervoneva
    Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA 19107, USA
    BMC Bioinformatics 11:253. 2010
  5. doi request reprint The influence of prognostic factors and adjuvant chemoradiation on survival after pancreaticoduodenectomy for ampullary carcinoma
    Timothy N Showalter
    Department of Radiation Oncology, Jefferson Medical College of Thomas Jefferson University, Kimmel Cancer Center, Philadelphia, PA, USA
    J Gastrointest Surg 15:1411-6. 2011
  6. pmc Constrained S-estimators for linear mixed effects models with covariance components
    Inna Chervoneva
    Division of Biostatistics, Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Stat Med 30:1735-50. 2011
  7. pmc Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine
    Peng Li
    Division of Clinical Pharmacology, Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, 1100 Walnut St MOB 810, Philadelphia, PA 19107, USA
    Am J Pathol 171:1847-58. 2007
  8. doi request reprint Effects of antiepileptic drugs on lipids, homocysteine, and C-reactive protein
    Scott Mintzer
    Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Ann Neurol 65:448-56. 2009
  9. ncbi request reprint The effectiveness of low-frequency stimulation for mapping cortical function
    Andro Zangaladze
    Department of Neurology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Epilepsia 49:481-7. 2008
  10. pmc Clinical need for continuous glucose monitoring in the hospital
    Jeffrey I Joseph
    The Artificial Pancreas Center, Department of Anesthesiology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    J Diabetes Sci Technol 3:1309-18. 2009

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Relative quantification based on logistic models for individual polymerase chain reactions
    Inna Chervoneva
    Division of Biostatistics, Department of Clinical Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Stat Med 26:5596-611. 2007
    ..Real kinetic RT-PCR data are used to compare the proposed and standard methods. The methods are applied to the clinical data from the ongoing study of guanylyl cyclase C as a biomarker for colorectal cancer...
  2. ncbi request reprint Statistical algorithm for assuring similar efficiency in standards and samples for absolute quantification by real-time reverse transcription polymerase chain reaction
    Inna Chervoneva
    Division of Biostatistics, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Anal Biochem 348:198-208. 2006
    ..These studies demonstrate that elimination of kinetic outliers from calibration standards and test samples improves the accuracy of absolute transcript quantification by RT-PCR...
  3. pmc Increased SIAH expression predicts ductal carcinoma in situ (DCIS) progression to invasive carcinoma
    Kathryn C Behling
    Department of Pathology, Thomas Jefferson University and Kimmel Cancer Center, Philadelphia, PA 19107, USA
    Breast Cancer Res Treat 129:717-24. 2011
    ..23, P = 0.067). In conclusion, SIAH may represent a useful prognostic biomarker that predicts DCIS progression to invasive breast cancer...
  4. pmc Selection of optimal reference genes for normalization in quantitative RT-PCR
    Inna Chervoneva
    Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA 19107, USA
    BMC Bioinformatics 11:253. 2010
    ..Current methods of selecting reference genes make an assumption of independence in their innate variation. This assumption is not always justified, which may lead to selecting a suboptimal set of reference genes...
  5. doi request reprint The influence of prognostic factors and adjuvant chemoradiation on survival after pancreaticoduodenectomy for ampullary carcinoma
    Timothy N Showalter
    Department of Radiation Oncology, Jefferson Medical College of Thomas Jefferson University, Kimmel Cancer Center, Philadelphia, PA, USA
    J Gastrointest Surg 15:1411-6. 2011
    ..Decisions regarding adjuvant therapy are influenced by factors such as nodal status, stage, and grade, but the influence of these individual variables on survival is unclear...
  6. pmc Constrained S-estimators for linear mixed effects models with covariance components
    Inna Chervoneva
    Division of Biostatistics, Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Stat Med 30:1735-50. 2011
    ..The proposed methodology is applied to jointly analyze repeated measures on three cholesterol components, HDL, LDL, and triglycerides...
  7. pmc Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine
    Peng Li
    Division of Clinical Pharmacology, Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, 1100 Walnut St MOB 810, Philadelphia, PA 19107, USA
    Am J Pathol 171:1847-58. 2007
    ..In the context of uniform loss of GC-C signaling during tumorigenesis, dysregulation of those homeostatic processes may contribute to mechanisms underlying colon cancer...
  8. doi request reprint Effects of antiepileptic drugs on lipids, homocysteine, and C-reactive protein
    Scott Mintzer
    Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Ann Neurol 65:448-56. 2009
    ..We sought to determine whether these drugs have an effect on cholesterol and other serological markers of vascular risk...
  9. ncbi request reprint The effectiveness of low-frequency stimulation for mapping cortical function
    Andro Zangaladze
    Department of Neurology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Epilepsia 49:481-7. 2008
    ..To establish the efficacy and safety of low-frequency electrical stimulation for cortical brain mapping...
  10. pmc Clinical need for continuous glucose monitoring in the hospital
    Jeffrey I Joseph
    The Artificial Pancreas Center, Department of Anesthesiology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    J Diabetes Sci Technol 3:1309-18. 2009
    ..Numerous available and up-and-coming technologies are targeted for the hospital patient population. Advantages and limitations of these devices are discussed herewith in...
  11. pmc Non-enzymatic glycation of type I collagen diminishes collagen-proteoglycan binding and weakens cell adhesion
    Kristin L Reigle
    Department of Medicine, Cardeza Foundation for Hematologic Research, Thomas Jefferson University, Philadelphia, Pennsylvania 19107 5099, USA
    J Cell Biochem 104:1684-98. 2008
    ..Therefore in vivo, collagen glycation may weaken PG-collagen interactions, thereby disrupting matrix integrity and cell-collagen interactions, adhesion, and migration...
  12. doi request reprint Overexpression of matrix metalloproteinase 9 in tumor epithelial cells correlates with colorectal cancer metastasis
    David S Zuzga
    Department of Pharmacology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Clin Transl Sci 1:136-41. 2008
    ..Thus, cancer cell MMP-9 represents a novel, selective prognostic and predictive factor that may be exploited for more effective disease stage stratification and therapeutic regimen selection in patients with colorectal cancer...
  13. pmc Prognostic significance of lymph node metastases and ratio in esophageal cancer
    Matthew Wilson
    Department of Surgery, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA
    J Surg Res 146:11-5. 2008
    ..The incidence of carcinoma of the distal esophagus and GE junction is rapidly increasing. A large single-center experience was reviewed to determine the impact of lymph node positivity and ratio on survival...
  14. ncbi request reprint A general approach for two-stage analysis of multilevel clustered non-Gaussian data
    Inna Chervoneva
    Division of Biostatistics, Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Biometrics 62:752-9. 2006
    ....
  15. ncbi request reprint Bile acids induce ectopic expression of intestinal guanylyl cyclase C Through nuclear factor-kappaB and Cdx2 in human esophageal cells
    Philip R Debruyne
    Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Gastroenterology 130:1191-206. 2006
    ..The present studies examine the expression of GC-C in normal tissues and tumors from esophagus and stomach and mechanisms regulating its expression by acid and bile acids...
  16. ncbi request reprint A multivariate test for population bioequivalence
    Inna Chervoneva
    Department of Pharmacology and Experimental Therapeutics, Division of Biostatistics, Thomas Jefferson University, Philadelphia, PA 19107, U S A
    Stat Med 26:1208-23. 2007
    ..The proposed methodology is illustrated with an example of testing equivalence of the spray pattern of nasal sprays...
  17. doi request reprint Prognostic markers and long-term outcomes in ductal carcinoma in situ of the breast treated with excision alone
    Phoebe Holmes
    Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA
    Cancer 117:3650-7. 2011
    ..We analyzed the significance of biological markers and tumor characteristics in predicting recurrence in a large series of DCIS patients with long-term follow-up treated with breast conservation surgery (BCS) alone...
  18. doi request reprint Tumor-derived interleukin-10 as a prognostic factor in stage III patients undergoing adjuvant treatment with an autologous melanoma cell vaccine
    Amit Mahipal
    Department of Medical Oncology, Thomas Jefferson University, 1025 Walnut Street, Philadelphia, PA 19107, USA
    Cancer Immunol Immunother 60:1039-45. 2011
    ....
  19. ncbi request reprint Latency to first seizure after temporal lobectomy predicts long-term outcome
    Sarah E Buckingham
    Jefferson Medical College, Philadelphia, Pennsylvania, USA
    Epilepsia 51:1987-93. 2010
    ..Little is known about the prognostic significance of the time from surgery to first seizure relapse in predicting long-term outcome...
  20. pmc Stromal CD10 and SPARC expression in ductal carcinoma in situ (DCIS) patients predicts disease recurrence
    Agnieszka K Witkiewicz
    Department of Pathology, Thomas Jefferson University, Philadelphia, PA, USA
    Cancer Biol Ther 10:391-6. 2010
    ..Thus, stromal CD10 and SPARC expression levels are promising markers of DCIS recurrence and warrant evaluation in larger prospective studies...
  21. ncbi request reprint Decorin regulates assembly of collagen fibrils and acquisition of biomechanical properties during tendon development
    Guiyun Zhang
    Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    J Cell Biochem 98:1436-49. 2006
    ..Our findings indicate that decorin is a key regulatory molecule and that the temporal switch from biglycan to decorin is an important event in the coordinate regulation of fibrillogenesis and tendon development...
  22. ncbi request reprint Importance of margin extent as a predictor of outcome after adjuvant radiotherapy for Gleason score 7 pT3N0 prostate cancer
    Richard K Valicenti
    Department of Radiation Oncology, Jefferson Medical College and Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Int J Radiat Oncol Biol Phys 58:1093-7. 2004
    ....
  23. ncbi request reprint Prostate-specific antigen and insulin-like growth factor binding protein-3 in nipple aspirate fluid are associated with breast cancer
    Edward R Sauter
    Department of Surgery, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Cancer Detect Prev 26:149-57. 2002
    ..001). When considered jointly, only NAF PSA was significant. Therefore, NAF PSA, and to a lesser extent NAF IGFBP-3 and serum PSA, seem to be important predictors of breast cancer...
  24. pmc Circulating testosterone and prostate-specific antigen in nipple aspirate fluid and tissue are associated with breast cancer
    Edward R Sauter
    Department of Surgery, Thomas Jefferson University Hospital, 1025 Walnut Street, Suite 605, Philadelphia, PA 19107, USA
    Environ Health Perspect 110:241-6. 2002
    ..NAF and serum PSA levels in postmenopausal women are correlated, suggesting that as laboratory assessment of PSA becomes more sensitive, serum PSA may become useful in identifying women with breast cancer...
  25. ncbi request reprint The prognostic significance of multiple morphologic features and biologic markers in ductal carcinoma in situ of the breast: a study of a large cohort of patients treated with surgery alone
    Dennis B Cornfield
    Department of Pathology, Health Network Laboratories Lehigh Valley Hospital, Allentown, Pennsylvania 18103, USA
    Cancer 100:2317-27. 2004
    ..To the authors' knowledge, very little is known regarding the prognostic significance of the many biologic markers that have been studied in DCIS in the past decade...