Research Topics
| George C BrainardSummaryAffiliation: Thomas Jefferson University Country: USA Publications
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Detail Information
Publications
Blue light from light-emitting diodes elicits a dose-dependent suppression of melatonin in humansKathleen E West
Dept of Neurology, Thomas Jefferson Univ, Philadelphia, Pennsylvania 19107, USA
J Appl Physiol 110:619-26. 2011....
Photons, clocks, and consciousnessGeorge C Brainard
Department of Neurology, Thomas Jefferson University, Philadelphia, PA 19107, USA
J Biol Rhythms 20:314-25. 2005..These findings open the door to innovations in light therapy for circadian and affective disorders, as well as possible architectural light applications...
Sensitivity of the human circadian system to short-wavelength (420-nm) lightGeorge C Brainard
Department of Neurology, Thomas Jefferson University, Philadelphia, PA 19107, USA
J Biol Rhythms 23:379-86. 2008..04). Together, the results clarify the visible short-wavelength sensitivity of the human melatonin suppression action spectrum. This basic physiological finding may be useful for optimizing lighting for therapeutic and other applications...
Dim light adaptation attenuates acute melatonin suppression in humansSamar A Jasser
Department of Neurology, Thomas Jefferson University, Philadelphia, PA 19107, USA
J Biol Rhythms 21:394-404. 2006....
Toward optimizing lighting as a countermeasure to sleep and circadian disruption in space flightRobert L Fucci
Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Acta Astronaut 56:1017-24. 2005..04 and p<0.002). These studies will help optimize lighting countermeasures to circadian and sleep disruption during spaceflight...
High-intensity red light suppresses melatoninJohn P Hanifin
Thomas Jefferson University, Philadelphia, PA 19107, USA
Chronobiol Int 23:251-68. 2006..That physiology, and its potential for responding to red light, has implications for domestic applications involving animal care, the lighting of typical human environments, and advanced applications such as space exploration...
Inferior retinal light exposure is more effective than superior retinal exposure in suppressing melatonin in humansGena Glickman
Department of Neurology, Jefferson Medical College, Philadelphia, PA 19107, USA
J Biol Rhythms 18:71-9. 2003..Findings suggest a greater sensitivity or denser distribution of photoreceptors in the inferior retina are involved in light detection for the retinohypothalamic tract of humans...
Photoreception for circadian, neuroendocrine, and neurobehavioral regulationJohn P Hanifin
Department of Neurology, Thomas Jefferson University, Philadelphia, PA 19107, USA
J Physiol Anthropol 26:87-94. 2007..These findings are important in understanding how humans adapt to lighting conditions in modern society and will provide the basis for major changes in future architectural lighting strategies...
Light during darkness and cancer: relationships in circadian photoreception and tumor biologySamar A Jasser
Department of Neurology, Light Research Program, Thomas Jefferson University, 1025 Walnut Street, Suite 507, Philadelphia, PA 19107, USA
Cancer Causes Control 17:515-23. 2006..Continued rigorous empirical inquiry into the physiology and clinical implications of these habitual, integrated aspects of life is highly warranted at this time...
Ocular input for human melatonin regulation: relevance to breast cancerGena Glickman
Department of Neurology, Jefferson Medical College, 1015 Walnut Street, Philadelphia, PA 19107, USA
Neuro Endocrinol Lett 23:17-22. 2002..It is now necessary to reevaluate lighting strategies, with consideration of circadian influences, in an effort to maximize physiological homeostasis and health...
Light therapy for seasonal affective disorder with blue narrow-band light-emitting diodes (LEDs)Gena Glickman
Department of Neurology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
Biol Psychiatry 59:502-7. 2006..45, p = .019 for average over the post-treatment times). CONCLUSIONS: Narrow bandwidth blue light at 607 microW/cm2 outperforms dimmer red light in reversing symptoms of major depression with a seasonal pattern...
A randomized, controlled trial of mindfulness-based art therapy (MBAT) for women with cancerDaniel A Monti
Thomas Jefferson University, Philadelphia, PA 19107, USA
Psychooncology 15:363-73. 2006..This investigation of MBAT provides initial encouraging data that support a possible future role for the intervention as a psychosocial treatment option for cancer patients...
Mindfulness-based stress reduction lowers psychological distress in medical studentsSteven Rosenzweig
Center for Integrative Medicine, Jefferson Medical College, Philadelphia, Pennsylvania, USA
Teach Learn Med 15:88-92. 2003..Mindfulness-based stress reduction (MBSR) is an educational intervention designed to improve coping skills and reduce emotional distress...
