Ryan J Bourgo

Summary

Affiliation: Thomas Jefferson University
Country: USA

Publications

  1. pmc RB deletion disrupts coordination between DNA replication licensing and mitotic entry in vivo
    Ryan J Bourgo
    Department of Cancer Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Mol Biol Cell 22:931-9. 2011
  2. pmc SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity
    Ryan J Bourgo
    Department of Cancer Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Mol Biol Cell 20:3192-9. 2009
  3. doi request reprint RB and p53 cooperate to prevent liver tumorigenesis in response to tissue damage
    A Kathleen McClendon
    Department of Cancer Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Gastroenterology 141:1439-50. 2011
  4. doi request reprint RB restricts DNA damage-initiated tumorigenesis through an LXCXE-dependent mechanism of transcriptional control
    Ryan J Bourgo
    Department of Cancer Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Mol Cell 43:663-72. 2011

Collaborators

Detail Information

Publications4

  1. pmc RB deletion disrupts coordination between DNA replication licensing and mitotic entry in vivo
    Ryan J Bourgo
    Department of Cancer Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Mol Biol Cell 22:931-9. 2011
    ..Combined, these findings demonstrate the critical role of RB in controlling cell-cycle transitions and underscore the importance of intrinsic tissue environments in resultant phenotypes...
  2. pmc SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity
    Ryan J Bourgo
    Department of Cancer Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Mol Biol Cell 20:3192-9. 2009
    ..Brg1 deficiency is associated with the appearance of micronuclei and aberrant mitoses that are a by-product of dissociated chromatin structure. Thus, Brg1 plays a critical role in maintaining chromatin structural integrity...
  3. doi request reprint RB and p53 cooperate to prevent liver tumorigenesis in response to tissue damage
    A Kathleen McClendon
    Department of Cancer Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Gastroenterology 141:1439-50. 2011
    ..We analyzed the cooperation of RB and p53 in liver development and pathogenesis of hepatocellular carcinoma...
  4. doi request reprint RB restricts DNA damage-initiated tumorigenesis through an LXCXE-dependent mechanism of transcriptional control
    Ryan J Bourgo
    Department of Cancer Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Mol Cell 43:663-72. 2011
    ..Together, these studies establish an essential role of the LXCXE binding motif for RB-mediated transcriptional control, response to genotoxic insult, and tumor suppression...